|
US6824777B1
(en)
|
1992-10-09 |
2004-11-30 |
Licentia Ltd. |
Flt4 (VEGFR-3) as a target for tumor imaging and anti-tumor therapy
|
|
US7423125B2
(en)
|
1995-08-01 |
2008-09-09 |
Vegenics Limited |
Antibodies to VEGF-C
|
|
JPH09154588A
(ja)
*
|
1995-10-07 |
1997-06-17 |
Toagosei Co Ltd |
Vegf結合性ポリペプチド
|
|
US6100071A
(en)
|
1996-05-07 |
2000-08-08 |
Genentech, Inc. |
Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production
|
|
DE69736222T2
(de)
*
|
1996-11-21 |
2007-05-24 |
Kyowa Hakko Kogyo K.K. |
Gegen humanen vegf-rezeptor flt-1 gerichteter, monoklonaler antikörper.
|
|
WO1998031794A1
(fr)
*
|
1997-01-17 |
1998-07-23 |
Toa Gosei Co., Ltd. |
Polypeptide liant le facteur vegf
|
|
US7125714B2
(en)
|
1997-02-05 |
2006-10-24 |
Licentia Ltd. |
Progenitor cell materials and methods
|
|
US6485942B1
(en)
*
|
1997-02-14 |
2002-11-26 |
Genentech, Inc. |
Variants of vascular endothelial cell growth factor having altered pharmacological properties, and recombinant methods of production
|
|
US6887674B1
(en)
|
1998-04-13 |
2005-05-03 |
California Institute Of Technology |
Artery- and vein-specific proteins and uses therefor
|
|
US6864227B1
(en)
|
1998-04-13 |
2005-03-08 |
California Institute Of Technology |
Artery-and vein-specific proteins and uses therefor
|
|
ATE489108T1
(de)
*
|
1998-10-09 |
2010-12-15 |
Vegenics Ltd |
Flt4 (vegfr-3) als ziel für tumornachweis (imaging) und antitumortherapie
|
|
HK1042114B
(zh)
|
1998-10-23 |
2006-09-29 |
Amgen K-A, Inc. |
与mp1受体结合并具有血小板生成活性的模拟二聚体血小板生成素肽
|
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
CN1342077A
(zh)
*
|
1998-11-06 |
2002-03-27 |
诺尔股份公司 |
抑制血管渗透性过高的形成
|
|
EP2016953A3
(de)
*
|
1998-12-22 |
2009-04-15 |
Genentech, Inc. |
Vaskuläre endotheliale Zellwachstumsfaktor-Antagonisten und Verwendungen
|
|
EP1553414A1
(de)
*
|
1999-04-13 |
2005-07-13 |
Medarex, Inc. |
Methoden zur Diagnose und Behandlung metastasierender Prostata-Tumore
|
|
US6833349B2
(en)
*
|
1999-06-08 |
2004-12-21 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating inflammatory skin diseases
|
|
MXPA01012630A
(es)
*
|
1999-06-08 |
2002-07-22 |
Regeneron Pharma |
Polipeptidos quimericos modificados con propiedades farmacocineticas mejoradas.
|
|
US7303746B2
(en)
|
1999-06-08 |
2007-12-04 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating eye disorders with modified chimeric polypeptides
|
|
US7070959B1
(en)
*
|
1999-06-08 |
2006-07-04 |
Regeneron Pharmaceuticals, Inc. |
Modified chimeric polypeptides with improved pharmacokinetic properties
|
|
US7396664B2
(en)
*
|
1999-06-08 |
2008-07-08 |
Regeneron Pharmaceuticals, Inc. |
VEGF-binding fusion proteins and nucleic acids encoding the same
|
|
US7087411B2
(en)
*
|
1999-06-08 |
2006-08-08 |
Regeneron Pharmaceuticals, Inc. |
Fusion protein capable of binding VEGF
|
|
US7306799B2
(en)
*
|
1999-06-08 |
2007-12-11 |
Regeneron Pharmaceuticals, Inc. |
Use of VEGF inhibitors for treatment of eye disorders
|
|
US20020142982A1
(en)
*
|
1999-09-02 |
2002-10-03 |
Timothy Hla |
Method for regulating angiogenesis
|
|
GB9928950D0
(en)
*
|
1999-12-07 |
2000-02-02 |
Metris Therapeutics Limited |
Binding protein
|
|
AU2001239884B2
(en)
|
2000-02-25 |
2006-08-10 |
Vegenics Limited |
Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators
|
|
AU5943201A
(en)
*
|
2000-05-03 |
2001-11-12 |
Amgen Inc |
Modified peptides as therapeutic agents
|
|
AU2002220720B2
(en)
*
|
2000-11-28 |
2006-09-14 |
Mondobiotech Ag |
Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
|
|
US7611711B2
(en)
*
|
2001-01-17 |
2009-11-03 |
Vegenics Limited |
VEGFR-3 inhibitor materials and methods
|
|
CA2435503C
(en)
|
2001-01-19 |
2011-02-22 |
Ludwig Institute For Cancer Research |
Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy
|
|
CN1555488A
(zh)
*
|
2001-07-12 |
2004-12-15 |
路德维格癌症研究院 |
淋巴管内皮细胞物质及方法
|
|
US20040214766A1
(en)
*
|
2001-10-01 |
2004-10-28 |
Kari Alitalo |
VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
|
|
US20030113324A1
(en)
*
|
2001-10-01 |
2003-06-19 |
Kari Alitalo |
Neuropilin/VEGF-C/VEGFR-3 materials and methods
|
|
US20030181377A1
(en)
*
|
2002-02-12 |
2003-09-25 |
Vanderbilt University |
Inhibition of VEGF receptor signaling reverses tumor resistance to radiotherapy
|
|
CA2485166A1
(en)
|
2002-05-21 |
2003-12-04 |
Amgen Inc. |
Substituted pyrimidinone and pyridinone compounds
|
|
EP2430923A1
(de)
*
|
2002-06-05 |
2012-03-21 |
Genentech, Inc. |
Zusammensetzungen und Verfahren zum Leberwachstum und Leberschutz
|
|
US7335362B2
(en)
*
|
2002-07-19 |
2008-02-26 |
Beth Israel Deaconess Medical Center |
Methods of treating pre-eclampsia or eclampsia
|
|
BRPI0312818B8
(pt)
*
|
2002-07-19 |
2021-05-25 |
Beth Israel Deaconess Medical Ct Inc |
uso de uma medida do nível do polipeptídeo sflt-1 em uma amostra de uma paciente e uso de uma medida dos níveis de pelo menos dois dos peptídeos sflt1, vegf livre ou polipeptídio pigf livre em uma amostra de um paciente usando um métrico
|
|
US7435419B2
(en)
*
|
2002-07-19 |
2008-10-14 |
Beth Israel Deaconess Medical Center |
Methods of diagnosing and treating pre-eclampsia or eclampsia
|
|
DK2261249T3
(en)
|
2002-09-12 |
2015-02-16 |
Oncotherapy Science Inc |
KDR peptides and vaccines comprising the same
|
|
US7432341B2
(en)
*
|
2002-10-24 |
2008-10-07 |
Valo Hsj, Limited Partnership |
Cytokine receptor modulators and method of modulating cytokine receptor activity
|
|
US20040120950A1
(en)
*
|
2002-12-20 |
2004-06-24 |
Kari Alitalo |
Modulation of VEGF-C/VEGFR-3 interactions in the treatment of rheumatoid arthritis
|
|
EP1594527A2
(de)
*
|
2003-02-04 |
2005-11-16 |
Ludwig Institute For Cancer Research |
Vegf-b und pdgf modulierung von stammzellen
|
|
EP1606305A4
(de)
|
2003-03-12 |
2009-06-24 |
Vasgene Therapeutics Inc |
Nukleinsäureverbindungen für die inhibierung von angiogenese und tumorwachstum
|
|
US7381410B2
(en)
|
2003-03-12 |
2008-06-03 |
Vasgene Therapeutics, Inc. |
Polypeptide compounds for inhibiting angiogenesis and tumor growth
|
|
WO2004103159A2
(en)
*
|
2003-05-14 |
2004-12-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods for modulating endometrium
|
|
WO2005016966A2
(en)
*
|
2003-05-16 |
2005-02-24 |
Receptor Biologix, Inc. |
Intron fusion proteins, and methods of identifying and using same
|
|
US7186699B2
(en)
|
2003-06-03 |
2007-03-06 |
Cell Genesys, Inc. |
Method for treating cancer by vector-mediated delivery of one or more anti-angiogenic or pro-apoptotic genes
|
|
CA2519875C
(en)
*
|
2003-06-06 |
2014-01-14 |
Regeneron Pharmaceuticals, Inc. |
Method of tumor regression with vegf inhibitors
|
|
EP1635860A2
(de)
*
|
2003-06-12 |
2006-03-22 |
Ludwig Institute For Cancer Research |
Verwendung von vegf-c oder vegf-d in der wiederherstellende chirurgie
|
|
WO2005016963A2
(en)
*
|
2003-06-12 |
2005-02-24 |
Ludwig Institute For Cancer Research |
Heparin binding veger-3 ligands
|
|
US7399612B2
(en)
|
2003-06-30 |
2008-07-15 |
Regeneron Pharmaceuticals, Inc. |
VEGF-binding fusion proteins and nucleic acids encoding the same
|
|
AR046510A1
(es)
*
|
2003-07-25 |
2005-12-14 |
Regeneron Pharma |
Composicion de un antagonista de vegf y un agente anti-proliferativo
|
|
NZ592039A
(en)
|
2003-08-27 |
2013-03-28 |
Ophthotech Corp |
Combination therapy for the treatment of ocular neovascular disorders
|
|
US7582726B2
(en)
*
|
2003-11-10 |
2009-09-01 |
Ghc Research Development Corporation |
VEGF receptor antagonists
|
|
US8003613B2
(en)
*
|
2003-11-17 |
2011-08-23 |
University Of Florida Research Foundation, Inc. |
Methods and compositions for inducing apoptosis
|
|
ATE507240T1
(de)
*
|
2004-03-05 |
2011-05-15 |
Vegenics Pty Ltd |
Materialien und verfahren für wachstumsfaktorbindende konstrukte
|
|
EP2275445A3
(de)
|
2004-03-12 |
2012-02-29 |
Vasgene Therapeutics, Inc. |
Ephb4-bindende Antikörper zur Inhibierung von Angiogenese und Tumorwachstum
|
|
DE602005025459D1
(de)
|
2004-03-12 |
2011-02-03 |
Vasgene Therapeutics Inc |
Ephb4-bindende antikörper zur inhibierung von angiogenese und tumorwachstum
|
|
AU2005244167A1
(en)
*
|
2004-05-04 |
2005-11-24 |
Beth Israel Deaconess Medical Center |
Methods and compositions for treatment of preeclampsia
|
|
US8618054B2
(en)
*
|
2004-05-05 |
2013-12-31 |
Valorisation-Rechereche Société en Commandite |
Interleukin-1 receptor antagonists, compositions, and methods of treatment
|
|
AU2005245896A1
(en)
*
|
2004-05-14 |
2005-12-01 |
Receptor Biologix, Inc. |
Cell surface receptor isoforms and methods of identifying and using the same
|
|
PL1767546T3
(pl)
*
|
2004-06-08 |
2012-07-31 |
Chengdu Kanghong Biotechnologies Co Ltd |
Hamujące angiogenezę białka chimeryczne i ich zastosowanie
|
|
CN1304427C
(zh)
*
|
2004-06-08 |
2007-03-14 |
成都康弘生物科技有限公司 |
抑制血管新生的融合蛋白质及其用途
|
|
CA2567686A1
(en)
*
|
2004-06-10 |
2005-12-29 |
Regeneron Pharmaceuticals, Inc. |
Use of vegf inhibitors for the treatment of human cancer
|
|
CA2576030A1
(en)
*
|
2004-08-09 |
2006-02-23 |
Alios Biopharma Inc. |
Synthetic hyperglycosylated, protease-resistant polypeptide variants, oral formulations and methods of using the same
|
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
|
US20080171033A1
(en)
*
|
2004-08-26 |
2008-07-17 |
Chiwen Chang |
Compositions and methods for treating diseases associated with angiogenesis and inflammation
|
|
CN101094688B
(zh)
|
2004-09-13 |
2013-05-01 |
建新公司 |
多聚构建体
|
|
CA2581423A1
(en)
|
2004-09-23 |
2006-03-30 |
Vasgene Therapeutics, Inc. |
Polipeptide compounds for inhibiting angiogenesis and tumor growth
|
|
WO2006034507A2
(en)
*
|
2004-09-24 |
2006-03-30 |
Beth Israel - Deaconess Medical Center |
Methods of diagnosing and treating complications of pregnancy
|
|
US7740849B2
(en)
*
|
2004-09-24 |
2010-06-22 |
Beth Israel Deaconess Medical Center |
Use of compounds that bind soluble endoglin and SFLT-1 for the treatment of pregnancy related hypertensive disorders
|
|
US7442778B2
(en)
|
2004-09-24 |
2008-10-28 |
Amgen Inc. |
Modified Fc molecules
|
|
BRPI0519096A2
(pt)
*
|
2004-12-15 |
2008-12-23 |
Beth Israel Hospital |
Ácidos nuclÉicos e polipeptÍdeos éteis para o diagnàstico e tratamento de complicaÇÕes na gravidez
|
|
EP1877438A2
(de)
|
2005-02-02 |
2008-01-16 |
Regeneron Pharmaceuticals, Inc. |
Verfahren zur behandlung von augenverletzungen durch lokale verabreichung eines vegf-inhibitors
|
|
AU2006213856B2
(en)
*
|
2005-02-11 |
2011-03-17 |
Regeneron Pharmaceuticals, Inc. |
Therapeutic combination of a VEGF antagonist (VEGF trap) and an anti-hypertensive agent
|
|
EP1855707B1
(de)
|
2005-02-28 |
2012-04-04 |
Oncotherapy Science, Inc. |
Epitop peptide, die vom vascular endothelial growth factor rezeptor 1 abgeleitet wurden und impfstoffe, die diese enthalten
|
|
WO2006099154A1
(en)
*
|
2005-03-11 |
2006-09-21 |
Regeneron Pharmaceuticals, Inc. |
Treating anemia by inhibition of vegf
|
|
HUE034109T2
(en)
|
2005-03-25 |
2018-01-29 |
Regeneron Pharma |
VEGF antagonist formulations
|
|
US20060234347A1
(en)
*
|
2005-04-13 |
2006-10-19 |
Harding Thomas C |
Targeting multiple angiogenic pathways for cancer therapy using soluble tyrosine kinase receptors
|
|
US20090170769A1
(en)
*
|
2005-05-13 |
2009-07-02 |
Pei Jin |
Cell surface receptor isoforms and methods of identifying and using the same
|
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
|
US7531172B2
(en)
|
2005-08-12 |
2009-05-12 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating diseases with a VEGF antagonist
|
|
IL172297A
(en)
|
2005-10-03 |
2016-03-31 |
Compugen Ltd |
Soluble vegfr-1 variants for diagnosis of preeclamsia
|
|
US7354582B2
(en)
*
|
2006-03-10 |
2008-04-08 |
Regeneron Pharmaceuticals, Inc. |
Use of VEGF antagonists for the treatment of malignant gliomas
|
|
EP2015768A1
(de)
*
|
2006-03-27 |
2009-01-21 |
Genentech, Inc. |
Verfahren zur behandlung von nierenleiden
|
|
US20070258976A1
(en)
*
|
2006-05-04 |
2007-11-08 |
Ward Keith W |
Combination Therapy for Diseases Involving Angiogenesis
|
|
US20090286271A1
(en)
*
|
2006-05-31 |
2009-11-19 |
Karumanchi Ananth S |
Methods of Diagnosing and Treating Complications of Pregnancy
|
|
SI2944306T1
(sl)
*
|
2006-06-16 |
2021-04-30 |
Regeneron Pharmaceuticals, Inc. |
Formulacije antagonista VEGF, primerne za intravitrealno dajanje
|
|
MY183404A
(en)
|
2006-12-19 |
2021-02-18 |
Genentech Inc |
Vegf-specific antagonists for adjuvant and neoadjuvant therapy and the treatment of early stage tumors
|
|
AU2014201795B2
(en)
*
|
2006-12-19 |
2016-05-19 |
Genentech, Inc. |
VEGF-specific antagonists for adjuvant and neoadjuvant therapy and the treatment of early stage tumors
|
|
EP2125895B1
(de)
*
|
2007-02-02 |
2015-04-08 |
Vegenics Pty Ltd |
Vegf-rezeptorantagonisten zur behandlung von allommunität bei organtransplantationen und atherosklerose
|
|
US10259860B2
(en)
*
|
2007-02-27 |
2019-04-16 |
Aprogen Inc. |
Fusion proteins binding to VEGF and angiopoietin
|
|
EP2574671B1
(de)
|
2007-03-19 |
2016-02-03 |
National Research Council Of Canada |
Antagonisten von Liganden und ihre Verwendung
|
|
US20080260820A1
(en)
*
|
2007-04-19 |
2008-10-23 |
Gilles Borrelly |
Oral dosage formulations of protease-resistant polypeptides
|
|
AU2008287427B2
(en)
|
2007-08-13 |
2014-10-09 |
Vasgene Therapeutics, Inc. |
Cancer treatment using humanized antibodies that bind to EphB4
|
|
WO2009045370A2
(en)
|
2007-09-28 |
2009-04-09 |
Intrexon Corporation |
Therapeutic gene-switch constructs and bioreactors for the expression of biotherapeutic molecules, and uses thereof
|
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
|
WO2010031168A1
(en)
*
|
2008-09-17 |
2010-03-25 |
National Research Council Of Canada |
HETERO-MULTIVALENT BINDING AGENTS FOR MEMBERS OF THE TGFβ SUPERFAMILY
|
|
WO2009153563A1
(en)
|
2008-06-18 |
2009-12-23 |
Oxford Biomedica (Uk) Limited |
Virus purification
|
|
PL2752189T3
(pl)
|
2008-11-22 |
2017-04-28 |
F. Hoffmann-La Roche Ag |
Zastosowanie przeciwciała anty-VEGF w połączeniu z chemioterapią do leczenia raka sutka
|
|
JO3672B1
(ar)
|
2008-12-15 |
2020-08-27 |
Regeneron Pharma |
أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
|
|
US20130064834A1
(en)
|
2008-12-15 |
2013-03-14 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating hypercholesterolemia using antibodies to pcsk9
|
|
CN101838329A
(zh)
*
|
2009-03-18 |
2010-09-22 |
嘉和生物药业有限公司 |
抗血管新生融合蛋白
|
|
TW201109029A
(en)
|
2009-06-11 |
2011-03-16 |
Oncotherapy Science Inc |
Vaccine therapy for choroidal neovascularization
|
|
SG10201510152RA
(en)
|
2009-07-13 |
2016-01-28 |
Genentech Inc |
Diagnostic methods and compositions for treatment of cancer
|
|
TW201106972A
(en)
|
2009-07-27 |
2011-03-01 |
Genentech Inc |
Combination treatments
|
|
MX336476B
(es)
|
2009-08-15 |
2016-01-20 |
Genentech Inc |
Terapia anti-angiogenesis para el tratamiento de cancer de mama previamente tratado.
|
|
SG179070A1
(en)
|
2009-09-11 |
2012-04-27 |
Genentech Inc |
Method to identify a patient with an increased likelihood of responding to an anti-cancer agent
|
|
MX2012002909A
(es)
|
2009-09-17 |
2012-04-19 |
Hoffmann La Roche |
Metodos y composiciones para su uso en diagnostico de pacientes con cancer.
|
|
WO2011075185A1
(en)
|
2009-12-18 |
2011-06-23 |
Oligasis |
Targeted drug phosphorylcholine polymer conjugates
|
|
TWI619509B
(zh)
|
2010-02-23 |
2018-04-01 |
建南德克公司 |
治療先前未經治療之ⅲ期或ⅳ期卵巢癌、輸卵管癌或原發性腹膜癌之卡鉑、太平洋紫杉醇與抗-vegf抗體之組合
|
|
WO2011106697A1
(en)
|
2010-02-25 |
2011-09-01 |
Schepens Eye Research Institute |
Therapeutic compositions for the treatment of dry eye disease
|
|
EP4450523A3
(de)
|
2010-04-02 |
2025-03-12 |
Amunix Pharmaceuticals, Inc. |
Bindungsfusionsproteine, bindungsfusionsprotein-arzneimittelkonjugate, xten-arzneimittelkonjugate sowie verfahren zur herstellung und verwendung davon
|
|
JP5965392B2
(ja)
|
2010-05-28 |
2016-08-03 |
オックスフォード バイオメディカ (ユーケー) リミテッド |
脳へのレンチウイルスベクターの送達
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
CN103109189A
(zh)
|
2010-07-19 |
2013-05-15 |
霍夫曼-拉罗奇有限公司 |
鉴定响应抗癌疗法的可能性升高的患者的方法
|
|
EP2596359A1
(de)
|
2010-07-19 |
2013-05-29 |
F.Hoffmann-La Roche Ag |
Verfahren zur identifizierung eines patienten mit erhöhter wahrscheinlichkeit des ansprechens auf eine antitumortherapie
|
|
HRP20180154T1
(hr)
|
2010-08-06 |
2018-03-09 |
Genzyme Corporation |
Pripravci vegf antagonista i njihova uporaba
|
|
CN103533950A
(zh)
|
2011-01-13 |
2014-01-22 |
瑞泽恩制药公司 |
Vegf拮抗剂在治疗血管生成眼病中的用途
|
|
MX385311B
(es)
|
2011-01-28 |
2025-03-18 |
Sanofi Biotechnology |
Anticuerpos humanos frente a pcsk9 para su uso en métodos de tratamiento de grupos concretos de pacientes.
|
|
JO3283B1
(ar)
|
2011-04-26 |
2018-09-16 |
Sanofi Sa |
تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI)
|
|
AR087305A1
(es)
|
2011-07-28 |
2014-03-12 |
Regeneron Pharma |
Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit
|
|
WO2013028541A1
(en)
|
2011-08-19 |
2013-02-28 |
Children's Medical Center Corporation |
Vegf-binding protein for blockade of angiogenesis
|
|
HUE069234T2
(hu)
|
2011-09-16 |
2025-02-28 |
Regeneron Pharma |
Eljárások lipoprotein(a)-szint csökkentésére proprotein-konvertáz szubtilizin/kexin 9 (PCSK9) inhibitorának beadásával
|
|
SI2825558T1
(sl)
|
2012-03-13 |
2019-08-30 |
F. Hoffmann-La Roche Ag |
Kombinirana terapija za zdravljenje raka jajčnikov
|
|
AU2013263076B2
(en)
|
2012-05-15 |
2017-08-31 |
Bristol-Myers Squibb Company |
Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
|
|
JP6312659B2
(ja)
|
2012-05-31 |
2018-04-18 |
ジェネンテック, インコーポレイテッド |
Pd−1系結合アンタゴニスト及びvegfアンタゴニストを用いた癌の治療方法
|
|
RU2015104001A
(ru)
|
2012-08-07 |
2016-09-27 |
Дженентек, Инк. |
Комбинированная терапия для лечения глиобластомы
|
|
US9106711B2
(en)
|
2012-09-04 |
2015-08-11 |
Telefonaktiebolaget L M Ericsson (Publ) |
Minimizing mapping and signaling for data path aggregation
|
|
WO2014093387A1
(en)
*
|
2012-12-10 |
2014-06-19 |
Kindred Biosciences, Inc. |
Vegf receptor fusion proteins for veterinary use
|
|
WO2014118643A2
(en)
|
2013-02-04 |
2014-08-07 |
Vascular Biogenics Ltd. |
Methods of inducing responsiveness to anti-angiogenic agent
|
|
MY199344A
(en)
|
2013-02-18 |
2023-10-24 |
Vegenics Pty Ltd |
Ligand binding molecules and uses thereof
|
|
KR102049990B1
(ko)
|
2013-03-28 |
2019-12-03 |
삼성전자주식회사 |
c-Met 항체 및 VEGF 결합 단편이 연결된 융합 단백질
|
|
US10274503B2
(en)
|
2013-05-08 |
2019-04-30 |
Vegenics Pty Limited |
Methods of using VEGF-C biomarkers for age-related macular degeneration (AMD) diagnosis
|
|
EP2997039B1
(de)
|
2013-05-14 |
2019-06-26 |
Siemens Healthcare Diagnostics Inc. |
Stabilisierte flüssige formulierungen mit rezeptoren
|
|
US10111953B2
(en)
|
2013-05-30 |
2018-10-30 |
Regeneron Pharmaceuticals, Inc. |
Methods for reducing remnant cholesterol and other lipoprotein fractions by administering an inhibitor of proprotein convertase subtilisin kexin-9 (PCSK9)
|
|
CN103319610B
(zh)
*
|
2013-07-05 |
2016-01-27 |
华博生物医药技术(上海)有限公司 |
重组融合蛋白及其制法和用途
|
|
KR102948178B1
(ko)
|
2013-07-12 |
2026-04-10 |
아스텔라스 유에스 엘엘씨 |
안과적 질환을 치료하거나 예방하기 위한 방법
|
|
WO2015035342A2
(en)
|
2013-09-08 |
2015-03-12 |
Oligasis Llc |
Factor viii zwitterionic polymer conjugates
|
|
EP3068803B1
(de)
|
2013-11-12 |
2021-01-20 |
Sanofi Biotechnology |
Dosierungsschemata zur verwendung von pcsk9 inhibitoren
|
|
US9914769B2
(en)
|
2014-07-15 |
2018-03-13 |
Kymab Limited |
Precision medicine for cholesterol treatment
|
|
GB201322798D0
(en)
|
2013-12-20 |
2014-02-05 |
Oxford Biomedica Ltd |
Production system
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
MX2016012285A
(es)
|
2014-03-24 |
2017-01-23 |
Genentech Inc |
Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.
|
|
WO2015153514A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists
|
|
RU2695332C2
(ru)
|
2014-05-15 |
2019-07-23 |
Бристол-Маерс Сквибб Компани |
Лечение рака легкого с помощью комбинации антитела против pd-1 и другого противоракового средства
|
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
|
CN107206068A
(zh)
|
2014-07-16 |
2017-09-26 |
赛诺菲生物技术公司 |
用于治疗杂合型家族性高胆固醇血症(heFH)患者的方法
|
|
WO2016008975A1
(en)
|
2014-07-18 |
2016-01-21 |
Sanofi |
Method for predicting the outcome of a treatment with aflibercept of a patient suspected to suffer from a cancer
|
|
WO2016025647A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and a cancer vaccine
|
|
WO2016025642A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2 and integrin-binding-fc-fusion protein
|
|
KR20210013299A
(ko)
|
2014-10-17 |
2021-02-03 |
코디악 사이언시스 인코포레이티드 |
부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
|
|
US9139653B1
(en)
|
2015-04-30 |
2015-09-22 |
Kymab Limited |
Anti-human OX40L antibodies and methods of treatment
|
|
JP2018514550A
(ja)
|
2015-04-28 |
2018-06-07 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
抗pd−1抗体および抗ctla−4抗体を使用するpd−l1陰性黒色腫の処置
|
|
WO2016176504A1
(en)
|
2015-04-28 |
2016-11-03 |
Bristol-Myers Squibb Company |
Treatment of pd-l1-positive melanoma using an anti-pd-1 antibody
|
|
US20180155429A1
(en)
|
2015-05-28 |
2018-06-07 |
Bristol-Myers Squibb Company |
Treatment of pd-l1 positive lung cancer using an anti-pd-1 antibody
|
|
US11078278B2
(en)
|
2015-05-29 |
2021-08-03 |
Bristol-Myers Squibb Company |
Treatment of renal cell carcinoma
|
|
HK1251474A1
(zh)
|
2015-06-08 |
2019-02-01 |
豪夫迈‧罗氏有限公司 |
使用抗ox40抗体和pd-1轴结合拮抗剂治疗癌症的方法
|
|
SI3858859T1
(sl)
|
2015-07-14 |
2026-03-31 |
Bristol-Myers Squibb Company |
Postopek zdravljenja raka z uporabo zaviralca imunskih kontrolnih točk; protitelo, ki se veže na receptor programirane celične smrti-1 (pd-1) ali ligand programirane celične smrti 1 (pd-l1)
|
|
KR20240172758A
(ko)
|
2015-08-18 |
2024-12-10 |
리제너론 파아마슈티컬스, 인크. |
지단백질 분리반출술을 경험하고 있는 고지혈증을 갖는 환자를 치료하기 위한 항-pcsk9 억제성 항체
|
|
KR20250057128A
(ko)
|
2015-12-30 |
2025-04-28 |
코디악 사이언시스 인코포레이티드 |
항체 및 이의 접합체
|
|
KR101685532B1
(ko)
*
|
2016-04-26 |
2016-12-13 |
한국프라임제약주식회사 |
혈관내피성장인자 수용체 융합단백질
|
|
IL292302B2
(en)
|
2016-05-20 |
2023-10-01 |
Biohaven Pharm Holding Co Ltd |
Use of glutamate modulating factors in cancer immunotherapy
|
|
JP7461741B2
(ja)
|
2016-06-20 |
2024-04-04 |
カイマブ・リミテッド |
抗pd-l1およびil-2サイトカイン
|
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
|
US10603358B2
(en)
|
2017-01-10 |
2020-03-31 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-Fc fusion protein and immune stimulator
|
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
|
AU2018266324B2
(en)
|
2017-05-06 |
2024-02-01 |
Regeneron Pharmaceuticals, Inc. |
Methods of treating eye disorders with APLNR antagonists and VEGF inhibitors
|
|
EP3694890A4
(de)
|
2017-10-12 |
2021-11-03 |
Immunowake Inc. |
Leichtkettiges antikörperfusionsprotein mit vegfr
|
|
US20210322574A1
(en)
|
2017-10-20 |
2021-10-21 |
Vascular Biogenics Ltd. |
Diagnostic methods for anti-angiogenic agent therapy
|
|
EP3710483A4
(de)
|
2017-11-16 |
2021-10-20 |
XL-protein GmbH |
Pasylierte vegfr/pdgfr-fusionsproteine und deren verwendung in der therapie
|
|
AU2018375398C1
(en)
|
2017-11-30 |
2026-01-15 |
Regeneron Pharmaceuticals, Inc. |
Use of a VEGF antagonist to treat angiogenic eye disorders
|
|
US11524053B2
(en)
|
2018-01-26 |
2022-12-13 |
The Regents Of The University Of California |
Methods and compositions for treatment of angiogenic disorders using anti-VEGF agents
|
|
US12071476B2
(en)
|
2018-03-02 |
2024-08-27 |
Kodiak Sciences Inc. |
IL-6 antibodies and fusion constructs and conjugates thereof
|
|
EP3937959A1
(de)
|
2019-03-13 |
2022-01-19 |
Vascular Biogenics Ltd. |
Verfahren zur antitumortherapie
|
|
IL290188B2
(en)
|
2019-07-31 |
2026-05-01 |
Memorial Sloan Kettering Cancer Center |
Dose planning for perfusion-modulated tumor with single-dose radiotherapy
|
|
AU2020364071A1
(en)
|
2019-10-10 |
2022-05-26 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
KR20220097492A
(ko)
|
2019-11-12 |
2022-07-07 |
옥스포드 바이오메디카(유케이) 리미티드 |
생산 시스템
|
|
AU2020393842A1
(en)
|
2019-11-25 |
2022-06-16 |
The Regents Of The University Of California |
Long-acting VEGF inhibitors for intraocular neovascularization
|
|
KR20240007293A
(ko)
|
2019-12-06 |
2024-01-16 |
리제너론 파아마슈티컬스, 인크. |
항-vegf 단백질 조성물 및 이를 생산하는 방법
|
|
JP2023513303A
(ja)
|
2020-02-13 |
2023-03-30 |
オックスフォード バイオメディカ(ユーケー)リミテッド |
レンチウイルスベクターの製造
|
|
US20230118587A1
(en)
|
2020-03-13 |
2023-04-20 |
Oxford Biomedica (Uk) Limited |
Lentiviral Vectors
|
|
MX2022013812A
(es)
|
2020-05-08 |
2022-12-15 |
Regeneron Pharma |
Trampas y mini-trampas de vegf y metodos para el tratamiento de trastornos oculares y cancer.
|
|
IL298039A
(en)
|
2020-05-11 |
2023-01-01 |
Regeneron Pharma |
Viral clearance through holding at low ph
|
|
GB202007199D0
(en)
|
2020-05-15 |
2020-07-01 |
Oxford Biomedica Ltd |
Viral vector production
|
|
EP4225330A1
(de)
|
2020-10-06 |
2023-08-16 |
Iovance Biotherapeutics, Inc. |
Behandlung von nsclc-patienten mit tumorinfiltrierenden lymphozytentherapien
|
|
GB202017725D0
(en)
|
2020-11-10 |
2020-12-23 |
Oxford Biomedica Ltd |
Method
|
|
GB202114530D0
(en)
|
2021-10-12 |
2021-11-24 |
Oxford Biomedica Ltd |
Retroviral vectors
|
|
GB202114532D0
(en)
|
2021-10-12 |
2021-11-24 |
Oxford Biomedica Ltd |
Lentiviral Vectors
|
|
GB202114528D0
(en)
|
2021-10-12 |
2021-11-24 |
Oxford Biomedica Ltd |
Lentiviral vectors
|
|
GB202114529D0
(en)
|
2021-10-12 |
2021-11-24 |
Oxford Biomedica Ltd |
Lentiviral vectors
|
|
GB202114534D0
(en)
|
2021-10-12 |
2021-11-24 |
Oxford Biomedica Ltd |
Novel viral regulatory elements
|
|
GB202117844D0
(en)
|
2021-12-09 |
2022-01-26 |
Oxford Biomedica Ltd |
Purification method
|
|
GB202211935D0
(en)
|
2022-08-16 |
2022-09-28 |
Oxford Biomedica Ltd |
envelope proteins
|