DK1294876T3 - EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse - Google Patents

EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse

Info

Publication number
DK1294876T3
DK1294876T3 DK01946701T DK01946701T DK1294876T3 DK 1294876 T3 DK1294876 T3 DK 1294876T3 DK 01946701 T DK01946701 T DK 01946701T DK 01946701 T DK01946701 T DK 01946701T DK 1294876 T3 DK1294876 T3 DK 1294876T3
Authority
DK
Denmark
Prior art keywords
polypeptides
methods
present
vegf
well
Prior art date
Application number
DK01946701T
Other languages
English (en)
Inventor
Napoleone Ferrara
William I Wood
Colin Watanabe
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1294876T3 publication Critical patent/DK1294876T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1858Platelet-derived growth factor [PDGF]
    • A61K38/1866Vascular endothelial growth factor [VEGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475Assays involving growth factors
    • G01N2333/515Angiogenesic factors; Angiogenin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
DK01946701T 2000-06-23 2001-06-22 EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse DK1294876T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21363700P 2000-06-23 2000-06-23
US23097800P 2000-09-07 2000-09-07
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same
PCT/US2001/020116 WO2002000711A2 (en) 2000-06-23 2001-06-22 Ev-vegf nucleic acids and polypeptides and methods of use

Publications (1)

Publication Number Publication Date
DK1294876T3 true DK1294876T3 (da) 2009-06-02

Family

ID=26908256

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01946701T DK1294876T3 (da) 2000-06-23 2001-06-22 EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse

Country Status (13)

Country Link
US (4) US20020172678A1 (da)
EP (2) EP2075334B1 (da)
JP (1) JP5081361B2 (da)
KR (1) KR100871735B1 (da)
CN (2) CN101269214B (da)
AT (1) ATE424458T1 (da)
AU (3) AU6871401A (da)
CA (1) CA2412612C (da)
DE (1) DE60137847D1 (da)
DK (1) DK1294876T3 (da)
ES (1) ES2323569T3 (da)
MX (1) MXPA03000150A (da)
WO (1) WO2002000711A2 (da)

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AU2002319402B2 (en) * 2001-06-28 2008-09-11 Domantis Limited Dual-specific ligand and its use
BR0212070A (pt) 2001-08-29 2004-09-28 Genentech Inc ácidos nucléicos e polipeptìdeos bv8 com atividade mitogênica
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US7696320B2 (en) 2004-08-24 2010-04-13 Domantis Limited Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
US9321832B2 (en) * 2002-06-28 2016-04-26 Domantis Limited Ligand
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WO2002000711A2 (en) 2002-01-03
KR20030011104A (ko) 2003-02-06
CN101269214A (zh) 2008-09-24
US7727536B2 (en) 2010-06-01
US8557238B2 (en) 2013-10-15
EP2075334B1 (en) 2013-11-20
AU2006252241A1 (en) 2007-01-25
HK1059452A1 (en) 2004-07-02
JP2004511432A (ja) 2004-04-15
KR100871735B1 (ko) 2008-12-03
ES2323569T3 (es) 2009-07-21
ATE424458T1 (de) 2009-03-15
US20070122412A1 (en) 2007-05-31
CA2412612A1 (en) 2002-01-03
EP2075334A1 (en) 2009-07-01
AU2006252241B2 (en) 2010-03-04
CA2412612C (en) 2013-04-30
US20050064522A1 (en) 2005-03-24
CN1449445A (zh) 2003-10-15
US20020172678A1 (en) 2002-11-21
MXPA03000150A (es) 2003-09-22
AU6871401A (en) 2002-01-08
AU2001268714B2 (en) 2006-09-21
US20100254999A1 (en) 2010-10-07
CN1449445B (zh) 2012-07-18
EP1294876B1 (en) 2009-03-04
EP1294876A2 (en) 2003-03-26
CN101269214B (zh) 2013-09-04
JP5081361B2 (ja) 2012-11-28
DE60137847D1 (de) 2009-04-16
HK1132298A1 (en) 2010-02-19
WO2002000711A3 (en) 2002-06-20
US7446168B2 (en) 2008-11-04

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