DK1294876T3 - EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse - Google Patents
EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelseInfo
- Publication number
- DK1294876T3 DK1294876T3 DK01946701T DK01946701T DK1294876T3 DK 1294876 T3 DK1294876 T3 DK 1294876T3 DK 01946701 T DK01946701 T DK 01946701T DK 01946701 T DK01946701 T DK 01946701T DK 1294876 T3 DK1294876 T3 DK 1294876T3
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptides
- methods
- present
- vegf
- well
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
- A61K38/1866—Vascular endothelial growth factor [VEGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/515—Angiogenesic factors; Angiogenin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21363700P | 2000-06-23 | 2000-06-23 | |
| US23097800P | 2000-09-07 | 2000-09-07 | |
| PCT/US2000/032678 WO2001040466A2 (en) | 1999-12-01 | 2000-12-01 | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| PCT/US2001/020116 WO2002000711A2 (en) | 2000-06-23 | 2001-06-22 | Ev-vegf nucleic acids and polypeptides and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1294876T3 true DK1294876T3 (da) | 2009-06-02 |
Family
ID=26908256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01946701T DK1294876T3 (da) | 2000-06-23 | 2001-06-22 | EV-VEGF-nukleinsyrer og -polypeptider samt fremgangsmåder til deres benyttelse |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20020172678A1 (da) |
| EP (2) | EP2075334B1 (da) |
| JP (1) | JP5081361B2 (da) |
| KR (1) | KR100871735B1 (da) |
| CN (2) | CN101269214B (da) |
| AT (1) | ATE424458T1 (da) |
| AU (3) | AU6871401A (da) |
| CA (1) | CA2412612C (da) |
| DE (1) | DE60137847D1 (da) |
| DK (1) | DK1294876T3 (da) |
| ES (1) | ES2323569T3 (da) |
| MX (1) | MXPA03000150A (da) |
| WO (1) | WO2002000711A2 (da) |
Families Citing this family (32)
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| US6956108B2 (en) * | 1997-06-16 | 2005-10-18 | Genentech, Inc. | PRO1184 antibodies |
| US7264801B2 (en) * | 1998-08-11 | 2007-09-04 | Genentech, Inc. | EG-VEGF nucleic acids and polypeptides and method of use |
| US20020172678A1 (en) * | 2000-06-23 | 2002-11-21 | Napoleone Ferrara | EG-VEGF nucleic acids and polypeptides and methods of use |
| US6485938B1 (en) * | 1999-11-16 | 2002-11-26 | Zymogenetics, Inc. | Nucleic acid molecules that encodes human Zven1 |
| CA2427800A1 (en) | 2000-11-03 | 2002-05-10 | The Regents Of The University Of California | Prokineticin polypeptides, related compositions and methods |
| US20050271663A1 (en) * | 2001-06-28 | 2005-12-08 | Domantis Limited | Compositions and methods for treating inflammatory disorders |
| AU2002319402B2 (en) * | 2001-06-28 | 2008-09-11 | Domantis Limited | Dual-specific ligand and its use |
| BR0212070A (pt) | 2001-08-29 | 2004-09-28 | Genentech Inc | ácidos nucléicos e polipeptìdeos bv8 com atividade mitogênica |
| US7498414B2 (en) * | 2002-03-04 | 2009-03-03 | Imclone Systems Incorporated | Human antibodies specific to KDR and uses thereof |
| WO2003088904A2 (en) * | 2002-04-15 | 2003-10-30 | The Regents Of The University Of California | Screening and therapeutic methods for treating circadian rhythm disorders |
| DE10229379A1 (de) * | 2002-06-26 | 2004-01-29 | Schering Ag | EG-VEGF Rezeptor Antagonisten |
| US7696320B2 (en) | 2004-08-24 | 2010-04-13 | Domantis Limited | Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor |
| US9321832B2 (en) * | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| EP1600459A3 (en) * | 2002-06-28 | 2005-12-07 | Domantis Limited | Ligand |
| CA2500962A1 (en) * | 2002-10-07 | 2004-04-15 | Zymogenetics, Inc. | Uses of human zven proteins and polynucleotides |
| JP2006523090A (ja) * | 2002-12-27 | 2006-10-12 | ドマンティス リミテッド | リガンドに、そしてリガンド受容体に特異的な二重特異性単一ドメイン抗体 |
| WO2004065419A1 (ja) * | 2003-01-22 | 2004-08-05 | Takeda Pharmaceutical Company Limited | 抗体およびその用途 |
| AU2004219592C1 (en) * | 2003-03-12 | 2011-02-24 | Genentech, Inc. | Use of Bv8 and/or EG-VEGF to promote hematopoiesis |
| GB0320238D0 (en) | 2003-08-29 | 2003-10-01 | Medical Res Council | Treatment of disease |
| EP1924603A2 (en) * | 2005-09-13 | 2008-05-28 | Zymogenetics, Inc. | Prok2 antagonists and methods of use |
| CN101454344A (zh) * | 2005-12-01 | 2009-06-10 | 杜门蒂斯有限公司 | 与白细胞介素-1受体1型结合的非竞争性域抗体形式 |
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| NZ580530A (en) * | 2007-06-06 | 2012-04-27 | Domantis Ltd | Anti vegf polypeptides, antibody variable domains and antagonists |
| CN112858672A (zh) * | 2013-01-30 | 2021-05-28 | 弗拉芒区生物技术研究所 | 用于筛选和药物发现目的的新型嵌合多肽 |
| WO2014201283A1 (en) * | 2013-06-12 | 2014-12-18 | The Regents Of The University Of California | Methods for protecting ovarian function |
| JP2015127307A (ja) * | 2013-12-27 | 2015-07-09 | 国立大学法人福井大学 | 抗prok1抗体による大腸癌の治療 |
| JP6320040B2 (ja) * | 2013-12-27 | 2018-05-09 | 国立大学法人福井大学 | 抗prok1抗体及び抗vegf抗体併用による大腸癌の治療 |
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| RU2662944C1 (ru) * | 2017-02-17 | 2018-07-31 | Общество с ограниченной ответственностью "Группа развития "АПЕКС" | Средство для лечения состояний человеческого организма, связанных с уменьшением уровня экспрессии гена prok 1 и/или уменьшением количества белка прокинетицина 1 на основе генно-терапевтических субстанций с геном prok 1, способ получения и использования |
| US11793889B2 (en) | 2018-09-24 | 2023-10-24 | Kinase Pharma Inc. | Methods for selective kinase inhibition by endogenously produced antagonists of one or more kinases |
| CN111621466B (zh) * | 2020-06-09 | 2020-12-29 | 首都医科大学附属北京朝阳医院 | 一种肺动脉组织单细胞悬液的制备方法及应用 |
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-
2001
- 2001-06-20 US US09/886,242 patent/US20020172678A1/en not_active Abandoned
- 2001-06-22 WO PCT/US2001/020116 patent/WO2002000711A2/en not_active Ceased
- 2001-06-22 ES ES01946701T patent/ES2323569T3/es not_active Expired - Lifetime
- 2001-06-22 DE DE60137847T patent/DE60137847D1/de not_active Expired - Lifetime
- 2001-06-22 EP EP09002242.7A patent/EP2075334B1/en not_active Expired - Lifetime
- 2001-06-22 AU AU6871401A patent/AU6871401A/xx active Pending
- 2001-06-22 CA CA2412612A patent/CA2412612C/en not_active Expired - Fee Related
- 2001-06-22 JP JP2002505833A patent/JP5081361B2/ja not_active Expired - Fee Related
- 2001-06-22 KR KR1020027017547A patent/KR100871735B1/ko not_active Expired - Fee Related
- 2001-06-22 AT AT01946701T patent/ATE424458T1/de not_active IP Right Cessation
- 2001-06-22 MX MXPA03000150A patent/MXPA03000150A/es active IP Right Grant
- 2001-06-22 DK DK01946701T patent/DK1294876T3/da active
- 2001-06-22 AU AU2001268714A patent/AU2001268714B2/en not_active Ceased
- 2001-06-22 CN CN2008100991719A patent/CN101269214B/zh not_active Expired - Fee Related
- 2001-06-22 CN CN018146007A patent/CN1449445B/zh not_active Expired - Fee Related
- 2001-06-22 EP EP01946701A patent/EP1294876B1/en not_active Expired - Lifetime
-
2003
- 2003-10-22 US US10/692,299 patent/US7446168B2/en not_active Expired - Fee Related
-
2006
- 2006-09-29 US US11/537,382 patent/US7727536B2/en not_active Expired - Fee Related
- 2006-12-20 AU AU2006252241A patent/AU2006252241B2/en not_active Ceased
-
2010
- 2010-03-16 US US12/724,964 patent/US8557238B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000711A2 (en) | 2002-01-03 |
| KR20030011104A (ko) | 2003-02-06 |
| CN101269214A (zh) | 2008-09-24 |
| US7727536B2 (en) | 2010-06-01 |
| US8557238B2 (en) | 2013-10-15 |
| EP2075334B1 (en) | 2013-11-20 |
| AU2006252241A1 (en) | 2007-01-25 |
| HK1059452A1 (en) | 2004-07-02 |
| JP2004511432A (ja) | 2004-04-15 |
| KR100871735B1 (ko) | 2008-12-03 |
| ES2323569T3 (es) | 2009-07-21 |
| ATE424458T1 (de) | 2009-03-15 |
| US20070122412A1 (en) | 2007-05-31 |
| CA2412612A1 (en) | 2002-01-03 |
| EP2075334A1 (en) | 2009-07-01 |
| AU2006252241B2 (en) | 2010-03-04 |
| CA2412612C (en) | 2013-04-30 |
| US20050064522A1 (en) | 2005-03-24 |
| CN1449445A (zh) | 2003-10-15 |
| US20020172678A1 (en) | 2002-11-21 |
| MXPA03000150A (es) | 2003-09-22 |
| AU6871401A (en) | 2002-01-08 |
| AU2001268714B2 (en) | 2006-09-21 |
| US20100254999A1 (en) | 2010-10-07 |
| CN1449445B (zh) | 2012-07-18 |
| EP1294876B1 (en) | 2009-03-04 |
| EP1294876A2 (en) | 2003-03-26 |
| CN101269214B (zh) | 2013-09-04 |
| JP5081361B2 (ja) | 2012-11-28 |
| DE60137847D1 (de) | 2009-04-16 |
| HK1132298A1 (en) | 2010-02-19 |
| WO2002000711A3 (en) | 2002-06-20 |
| US7446168B2 (en) | 2008-11-04 |
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