DK0941738T3 - Antigene konjugater af bevarede lipooligosaccharider af gramnegative bakterier - Google Patents

Antigene konjugater af bevarede lipooligosaccharider af gramnegative bakterier

Info

Publication number: DK0941738T3
Authority: DK; Denmark
Prior art keywords: negative bacteria; conserved; gram; lipooligosaccharides; lipopolysaccharide
Prior art date: 1998-03-10

Application number

DK99301747T

Other languages

Danish (da)

English (en)

Inventor

Rasappa G Arumugham

Maria Fortuna-Nevin

Michael A Apicella

Bradford W Gibson

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-10

Filing date

1999-03-09

Publication date

2005-08-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21894823&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0941738(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-03-09 Application filed by Wyeth Corp filed Critical Wyeth Corp

2005-08-08 Application granted granted Critical

2005-08-08 Publication of DK0941738T3 publication Critical patent/DK0941738T3/da

Links

241000894006 Bacteria Species 0.000 title abstract 3
230000000890 antigenic effect Effects 0.000 title abstract 2
239000002158 endotoxin Substances 0.000 abstract 3
229920006008 lipopolysaccharide Polymers 0.000 abstract 3
102000014914 Carrier Proteins Human genes 0.000 abstract 1
108010078791 Carrier Proteins Proteins 0.000 abstract 1
230000028993 immune response Effects 0.000 abstract 1
GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical compound O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Immunology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Microbiology (AREA)
Epidemiology (AREA)
Mycology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DK99301747T 1998-03-10 1999-03-09 Antigene konjugater af bevarede lipooligosaccharider af gramnegative bakterier DK0941738T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US3752998A	1998-03-10	1998-03-10
EP99301747A EP0941738B1 (de)	1998-03-10	1999-03-09	Antigenkonjugate von konservierten Lipooligosacchariden aus gram-negativen Bakterien

Publications (1)

Publication Number	Publication Date
DK0941738T3 true DK0941738T3 (da)	2005-08-08

Family

ID=21894823

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99301747T DK0941738T3 (da)	1998-03-10	1999-03-09	Antigene konjugater af bevarede lipooligosaccharider af gramnegative bakterier

Country Status (12)

Country	Link
EP (1)	EP0941738B1 (de)
JP (1)	JPH11322793A (de)
KR (1)	KR100628664B1 (de)
AT (1)	ATE295181T1 (de)
AU (2)	AU766184B2 (de)
BR (1)	BR9902008A (de)
CA (1)	CA2264970A1 (de)
DE (1)	DE69925187T2 (de)
DK (1)	DK0941738T3 (de)
ES (1)	ES2241240T3 (de)
PT (1)	PT941738E (de)
SI (1)	SI0941738T1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2364726A3 (de) *	1999-09-30	2011-11-09	Isis Innovation Limited	Impfstoff gegen Neisseria-Infektion
WO2001078787A2 (en)	2000-04-18	2001-10-25	Endobiologics, Incorporated	Lipopolysaccharide-conjugate vaccine for sepsis treatment
US7749511B2 (en)	2000-04-18	2010-07-06	Endobiologics, Incorporated	Anti-sepsis conjugate vaccine
ES2284681T3 (es)	2000-08-25	2007-11-16	Aventis Pasteur Limited	Epitopos de oligosacaridos del nucleo de lipopolisacaridos de maemophilus influenzae como vacunas para la prevencion de infecciones por haemophilus influenzae.
US7527797B1 (en) *	2000-09-01	2009-05-05	The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services	Vibrio cholerae 0139 conjugate vaccines
EP1374892A1 (de) *	2002-06-28	2004-01-02	Braun, Jan Matthias, Dr.	Arzneimittel zur Behandlung von infektiösen Krankheiten infolge Neisseria Meningitidis
US20060057160A1 (en) *	2002-08-02	2006-03-16	Ralph Biemans	Vaccine composition
PL229487B1 (pl)	2002-11-12	2018-07-31	Brigham & Womens Hospital Inc	Kompozycja zawierająca polimer β-1,6-glukozaminy, kompozycja zawierająca przeciwciało, kompozycja farmaceutyczna, sposób wytwarzania wyodrębnionego polisacharydu, sposób identyfikacji obecności deacetylowanej poli-N-acetyloglukozaminy (dPNAG) i/ lub poli-N-acetyloglukozaminy (PNAG), wyodrębniony polisacharyd do zastosowania w leczeniu lub profilaktyce zakażenia, wyodrębniony polisacharyd do zastosowania do wytwarzania przeciwciał, w tym przeciwciał monoklonalnych, wyodrębniony polisacharyd do zastosowania w identyfikacji przeciwciała monoklonalnego
JP4696079B2 (ja)	2003-12-17	2011-06-08	ヤンセンアルツハイマーイミュノセラピー	Ａβ免疫原性ペプチド担体結合物およびそれの製造方法
KR101157694B1 (ko) *	2003-12-17	2012-06-20	와이어쓰 엘엘씨	면역원성 펩티드 캐리어 컨쥬게이트 및 이의 제조 방법
BRPI0519923A8 (pt) *	2004-12-17	2018-01-23	De Staat Der Nederlanden Vertegenwoordigd Door De Mini Van Vws	polipeptídeo, seqüência de dna, vetor de dna, anticorpo, bactéria, método para produzir lps parcialmente 3-0-desacilado, composição, usos da bactéria, e de lps de bordetella isolado compreendendo lps pelo menos parcialmente 3-0-desacilado, vacina, e, método in vitro para a desacilação de lps gram-negativo ou de composições compreendendo lps gram-negativo, e, para induzir uma resposta imune contra bordetella.
PE20110072A1 (es)	2005-06-27	2011-02-04	Glaxosmithkline Biolog Sa	Composicion inmunogenica
TW200806315A (en) *	2006-04-26	2008-02-01	Wyeth Corp	Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
CA2654706A1 (en)	2006-06-12	2007-12-21	Nathalie Devos	Neisseria meningitidis lipooligosaccharide vaccine
CN102159540B (zh)	2008-07-21	2015-08-12	布赖汉姆妇女医院	与合成的β-1,6葡糖胺寡糖相关的方法和组合物
CA2761924C (fr)	2009-05-14	2017-10-31	Sanofi Pasteur	Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6
WO2010130896A2 (fr)	2009-05-14	2010-11-18	Sanofi Pasteur	Procédé pour adjuver le lipopolysaccharide (lps) des bactéries à gram-négatif
WO2010134225A1 (ja) *	2009-05-20	2010-11-25	国立大学法人鳥取大学	部分糖鎖エピトープを用いた、病原性ナイセリア属細菌感染の検出方法およびそれら細菌に対するワクチン
CA2792687A1 (en)	2010-03-10	2011-09-15	Glaxosmithkline Biologicals S.A.	Immunogenic composition
PL2575870T3 (pl)	2010-06-04	2017-05-31	Wyeth Llc	Preparaty szczepionek
PL404229A1 (pl)	2013-06-06	2014-12-08	Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Odpowiedzialnością	Wyizolowany immunogenny antygen bakteryjny i jego zastosowanie w profilaktyce i leczeniu zakażeń wywołanych przez Gram-ujemne bakterie
CN103308686B (zh) *	2013-06-28	2016-04-06	武汉云克隆科技股份有限公司	脂多糖酶联免疫吸附测定试剂盒的制备方法
KR101509456B1 (ko) *	2013-10-04	2015-04-14	아이진 주식회사	리포폴리사카라이드 유사체 및 이를 포함하는 면역보조 조성물
CN104352762A (zh) *	2014-12-11	2015-02-18	谭清平	一种用于治疗脓毒症的中药及其制备方法
BR112019003992A2 (pt)	2016-09-02	2019-05-28	Sanofi Pasteur Inc	vacina contra neisseria meningitidis
BR112019010227A2 (pt) *	2016-11-25	2019-10-08	Glaxosmithkline Biologicals S.A.	conjugado imunogênico, processo para preparação de conjugado imunogênico, composição imunogênica, vacina, e, uso de nomv
US12397014B2 (en)	2019-02-05	2025-08-26	The Brigham And Women's Hospital, Inc.	Polysaccharide compositions for use in treating filariasis
CN112125832B (zh) *	2020-08-12	2022-09-20	北京大学	刺突蛋白受体结合结构域纳米凝胶及其制备方法与应用
AU2022241364A1 (en) *	2021-03-15	2023-10-05	Griffith University	Pathogen moieties and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6887483B2 (en) *	1995-12-01	2005-05-03	University Of Iowa Research Foundation	Non-toxic mutants of pathogenic gram-negative bacteria

1999
- 1999-03-08 CA CA002264970A patent/CA2264970A1/en not_active Abandoned
- 1999-03-09 ES ES99301747T patent/ES2241240T3/es not_active Expired - Lifetime
- 1999-03-09 BR BR9902008-4A patent/BR9902008A/pt not_active Application Discontinuation
- 1999-03-09 PT PT99301747T patent/PT941738E/pt unknown
- 1999-03-09 DE DE69925187T patent/DE69925187T2/de not_active Expired - Fee Related
- 1999-03-09 SI SI9930797T patent/SI0941738T1/xx unknown
- 1999-03-09 AU AU19540/99A patent/AU766184B2/en not_active Ceased
- 1999-03-09 KR KR1019990007668A patent/KR100628664B1/ko not_active Expired - Fee Related
- 1999-03-09 JP JP11061354A patent/JPH11322793A/ja active Pending
- 1999-03-09 EP EP99301747A patent/EP0941738B1/de not_active Revoked
- 1999-03-09 AT AT99301747T patent/ATE295181T1/de not_active IP Right Cessation
- 1999-03-09 DK DK99301747T patent/DK0941738T3/da active
2004
- 2004-01-07 AU AU2004200060A patent/AU2004200060B2/en not_active Ceased

Also Published As

Publication number	Publication date
CA2264970A1 (en)	1999-09-10
ES2241240T3 (es)	2005-10-16
ATE295181T1 (de)	2005-05-15
AU766184B2 (en)	2003-10-09
AU1954099A (en)	1999-09-23
PT941738E (pt)	2005-09-30
KR100628664B1 (ko)	2006-09-27
JPH11322793A (ja)	1999-11-24
AU2004200060B2 (en)	2005-10-13
DE69925187D1 (de)	2005-06-16
SI0941738T1 (en)	2005-10-31
DE69925187T2 (de)	2006-03-09
AU2004200060A1 (en)	2004-01-29
EP0941738A1 (de)	1999-09-15
EP0941738B1 (de)	2005-05-11
BR9902008A (pt)	2000-05-09
KR19990077705A (ko)	1999-10-25

Publication	Publication Date	Title
DK0941738T3 (da)	2005-08-08	Antigene konjugater af bevarede lipooligosaccharider af gramnegative bakterier
ATE397456T1 (de)	2008-06-15	Enterokokkus antigene und vakzine
FI862370A0 (fi)	1986-06-03	Monoklonaalisia vasta-aineita syklosporiineille
NO902909L (no)	1990-08-27	T-celle-epitop som baerermolekyl for konjugat-vaksiner.
DK98595A (da)	1995-09-07	Kovalent modificering af et polyanionisk polysaccharid
FI951568A0 (fi)	1995-04-03	Immobilisoitu beta-mannaasi
EP0694309A3 (de)	1998-04-22	Vakzine, Antigene und Antikörper enthaltende Zusammensetzung für den Schutz und die Hemmung von durch Staphylococcus induzierten Infektionen
AU570405B2 (en)	1988-03-17	Conjugates of muramyl-peptides and haptenes
ES553425A0 (es)	1987-11-01	Perfeccionamientos en la fabricacion de conjugados de proteinas portadores de antigenos inmunogenicos para vacunas contra la malaria
DK101196A (da)	1996-09-17	Histaminderivat, histamin-immunogen-konjugat samt antistof fremstillet mod konjugatet
DE59707944D1 (de)	2002-09-19	Elektromotor
AU3841993A (en)	1993-11-11	Synthetic lipid a glycoconjugate antigens for use in vaccines
Akiyama et al.	1997	Correction To" Scratch Drive Actuator With Mechanical Links For Self-assembly Of Three-dimensional MEMS"
CO5050385A1 (es)	2001-06-27	Derivados de proteinas de fusion mage