DK0941994T3 - Pyrazolopyrimidiner og pyrazolotriaziner med 5-HT6 receptoraffinitet - Google Patents

Pyrazolopyrimidiner og pyrazolotriaziner med 5-HT6 receptoraffinitet

Info

Publication number: DK0941994T3
Authority: DK; Denmark
Prior art keywords: pyrazolotriazines; pyrazolopyrimidines; receptor affinity; affinity; receptor
Prior art date: 1998-03-11

Application number

DK99102872T

Other languages

English (en)

Inventor

Michael Boes

Claus Riemer

Heinz Stadler

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-11

Filing date

1999-03-03

Publication date

2003-09-08

1999-03-03 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2003-09-08 Application granted granted Critical

2003-09-08 Publication of DK0941994T3 publication Critical patent/DK0941994T3/da

Links

APXRHPDHORGIEB-UHFFFAOYSA-N 1H-pyrazolo[4,3-d]pyrimidine Chemical class N1=CN=C2C=NNC2=C1 APXRHPDHORGIEB-UHFFFAOYSA-N 0.000 title 1
108091005435 5-HT6 receptors Proteins 0.000 title 1
PEYVWBGHBCDXRT-UHFFFAOYSA-N N1=NNC2=CN=NC2=C1 Chemical class N1=NNC2=CN=NC2=C1 PEYVWBGHBCDXRT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Psychiatry (AREA)
Psychology (AREA)
Vascular Medicine (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK99102872T 1998-03-11 1999-03-03 Pyrazolopyrimidiner og pyrazolotriaziner med 5-HT6 receptoraffinitet DK0941994T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP98104346		1998-03-11

Publications (1)

Publication Number	Publication Date
DK0941994T3 true DK0941994T3 (da)	2003-09-08

Family

ID=8231568

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99102872T DK0941994T3 (da)	1998-03-11	1999-03-03	Pyrazolopyrimidiner og pyrazolotriaziner med 5-HT6 receptoraffinitet

Country Status (33)

Country	Link
US (1)	US6194410B1 (da)
EP (1)	EP0941994B1 (da)
JP (1)	JP3231288B2 (da)
KR (1)	KR100313181B1 (da)
CN (1)	CN1118468C (da)
AR (1)	AR016453A1 (da)
AT (1)	ATE240332T1 (da)
AU (1)	AU752408B2 (da)
BR (1)	BR9901095A (da)
CA (1)	CA2265095C (da)
CZ (1)	CZ291514B6 (da)
DE (1)	DE69907784T2 (da)
DK (1)	DK0941994T3 (da)
ES (1)	ES2198095T3 (da)
HR (1)	HRP990077B1 (da)
HU (1)	HUP9900589A1 (da)
ID (1)	ID23575A (da)
IL (1)	IL128869A (da)
MA (1)	MA26612A1 (da)
MY (1)	MY119536A (da)
NO (1)	NO312297B1 (da)
NZ (1)	NZ334526A (da)
PE (1)	PE20000337A1 (da)
PL (1)	PL331875A1 (da)
PT (1)	PT941994E (da)
RU (1)	RU2218340C2 (da)
SG (1)	SG78336A1 (da)
SI (1)	SI0941994T1 (da)
TR (1)	TR199900531A3 (da)
TW (1)	TW585865B (da)
UY (1)	UY25419A1 (da)
YU (1)	YU12099A (da)
ZA (1)	ZA991946B (da)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2000059907A2 (en)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolotriazines as crf antagonists
DE19956791A1 (de) *	1999-11-25	2001-05-31	Merck Patent Gmbh	Neue Sulfonyloxazolamine
PE20020394A1 (es)	2000-08-18	2002-06-21	Agouron Pharma	Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2
IL157615A0 (en) *	2001-03-13	2004-03-28	Bristol Myers Squibb Co	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl) pyrazolo-[1,5-a]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands
JP4187642B2 (ja)	2001-06-07	2008-11-26	エフ．ホフマン−ラロシュアーゲー	５−ｈｔ６受容体親和性を有する新規インドール誘導体
ES2268113T3 (es)	2001-06-15	2007-03-16	F. Hoffmann-La Roche Ag	Derivados de 4-piperazinilindol con afinidad al receptor 5-ht6.
JP2005527463A (ja) *	2001-08-07	2005-09-15	スミスクライン　ビーチャム　パブリック　リミテッド　カンパニー	Ｃｎｓ疾患を治療するための５−ｈｔ６受容体アフィニティーを有する３−アリールスルホニル−７−ピペラジニル−インドール、−ベンゾフランおよび−ベンゾチオフェン
AU2002357270B2 (en) *	2001-12-20	2007-06-14	Wyeth	Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
US6642381B2 (en) *	2001-12-27	2003-11-04	Hoffman-La Roche Inc.	Pyrimido[5,4-e][1,2,4]triazine-5,7-diamine compounds as protein tyrosine phosphatase inhibitors
GB0202679D0 (en) *	2002-02-05	2002-03-20	Glaxo Group Ltd	Novel compounds
UA78999C2 (en) *	2002-06-04	2007-05-10	Wyeth Corp	1-(aminoalkyl)-3-sulfonylazaindoles as ligands of 5-hydroxytryptamine-6
US6875771B2 (en)	2002-07-26	2005-04-05	Bristol-Myers Squibb Company	Pyridopyrimidine derivatives as 5-HT6 antagonists
US7196078B2 (en) *	2002-09-04	2007-03-27	Schering Corpoartion	Trisubstituted and tetrasubstituted pyrazolopyrimidines as cyclin dependent kinase inhibitors
RU2380369C9 (ru) *	2002-09-04	2011-07-10	Шеринг Корпорейшн	Новые пиразолопиримидины как ингибиторы циклин-зависимой киназы
US7329658B2 (en) *	2003-02-06	2008-02-12	Pfizer Inc	Cannabinoid receptor ligands and uses thereof
AU2004213375A1 (en) *	2003-02-14	2004-09-02	Wyeth	Heterocyclyl-3-sulfonylazaindole or -azaindazole derivatives as 5-Hydroxytryptamine-6 ligands
EP1599482A4 (en)	2003-02-28	2008-10-01	Teijin Pharma Ltd	PYRAZOLO1,5-A PYRIMIDINE DERIVATIVES
GB0305559D0 (en) *	2003-03-11	2003-04-16	Teijin Ltd	Compounds
US7585881B2 (en) *	2004-02-18	2009-09-08	Astrazeneca Ab	Additional heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
WO2005112936A1 (en) *	2004-05-14	2005-12-01	The Regents Of The University Of Michigan	Compositions and methods relating to protein kinase inhibitors
EP1812440B1 (en) *	2004-11-04	2010-09-22	Vertex Pharmaceuticals, Inc.	Pyrazolo[1,5-a]pyrimidines useful as inhibitors of protein kinases
RU2390523C2 (ru) *	2005-10-21	2010-05-27	Мицубиси Танабе Фарма Корпорейшн	ПРОИЗВОДНОЕ ПИРАЗОЛ[1,5-a]ПИРИМИДИНА
RU2330854C2 (ru) *	2006-03-15	2008-08-10	Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУВПО "ПГФА Росздрава")	Способ получения конденсированных гем-диметилзамещенных амино-1,3,5-триазинов
JP5584626B2 (ja) *	2008-01-24	2014-09-03	アンドレイ・アレクサンドロビッチ・イワシェンコ	２−アルキルアミノ−３−（アリールスルホニル）−シクロアルキル［ｅ又はｄ］ピラゾロ［１，５−ａ］ピリミジン−セロトニン５−ＨＴ６受容体アンタゴニスト、その調製の方法及び使用
EA017968B1 (ru)	2008-01-24	2013-04-30	Андрей Александрович ИВАЩЕНКО	ЗАМЕЩЕННЫЕ 2-АМИНО-3-СУЛЬФОНИЛПИРАЗОЛО[1,5-a]ПИРИМИДИНЫ-АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-НТРЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
US8629154B2 (en) *	2008-01-24	2014-01-14	Andrey Alexandrovich Ivashchenko	Substituted cycloalcano[e and d] pyrazolo [1,5-a]pyrimidines/antagonists of serotonin 5-HT6 receptors and methods for production and the use thereof
RU2369600C1 (ru)	2008-01-24	2009-10-10	Андрей Александрович Иващенко	ЗАМЕЩЕННЫЕ 4-СУЛЬФОНИЛ-ПИРАЗОЛЫ И 3-СУЛЬФОНИЛ-ПИРАЗОЛО[1,5-a]ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ5-HT6 РЕЦЕПТОРОВ, АКТИВНЫЙ КОМПОНЕНТ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ЛЕКАРСТВЕННОЕ СРЕДСТВО И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
RU2384581C2 (ru)	2008-05-07	2010-03-20	Андрей Александрович Иващенко	ЗАМЕЩЕННЫЕ 2-АМИНО-3-СУЛЬФОНИЛ-ТЕТРАГИДРО-ПИРАЗОЛО[1,5-a]ПИРИДО-ПИРИМИДИНЫ - АНТАГОНИСТЫ СЕРОТОНИНОВЫХ 5-HT6 РЕЦЕПТОРОВ, СПОСОБЫ ИХ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ
WO2010041983A1 (ru)	2008-10-06	2010-04-15	Алла Хем, Ллс	Замещенные 3-арилсульфoнил-пиpaзoлo[1,5-a]пиpимидины, антагонисты серотониновых 5-ht6 рецепторов, способы их получения и применения
EP2384328B1 (en)	2008-11-27	2013-02-13	Boehringer Ingelheim International GmbH	6,7,8,9-tetrahydro-5h-1,4,7,10a-tetraaza-cyclohept[f]indene derivatives, pharmaceutical compositions containing these compounds, their use and process for preparing them
GB0908394D0 (en)	2009-05-15	2009-06-24	Univ Leuven Kath	Novel viral replication inhibitors
GB0913636D0 (en)	2009-08-05	2009-09-16	Univ Leuven Kath	Novel viral replication inhibitors
NZ610315A (en)	2010-11-15	2015-08-28	Univ Leuven Kath	Antiviral condensed heterocyclic compounds
RU2443697C1 (ru)	2010-12-21	2012-02-27	Александр Васильевич Иващенко	Замещенные метил-амины, антагонисты серотониновых 5-ht6 рецепторов, способы получения и применения
MX342177B (es)	2011-09-30	2016-09-20	Ipsen Pharma Sas	Inhibidores de cinasa 2 de repeticion rica en leucina (lrrk2) macrociclica.
CN104302649B (zh)	2012-03-09	2017-06-23	莱西肯医药有限公司	基于吡唑并[1,5‑a]嘧啶的化合物、包含它们的组合物及其使用方法
TW201542550A (zh) *	2013-09-06	2015-11-16	Lexicon Pharmaceuticals Inc	吡唑并［１，５－ａ］嘧啶基化合物、包含彼之組合物以及使用彼之方法
TW201620911A (zh) *	2014-03-17	2016-06-16	雷西肯製藥股份有限公司	銜接子關聯激酶１之抑制劑、包含其之組成物、及其使用方法
BR112017005299A2 (pt)	2014-09-17	2017-12-12	Ipsen Pharma Sas	inibidores de lrrk2 cinase macrocíclicos
CA2978170C (en)	2015-03-09	2024-02-27	Aurigene Discovery Technologies Limited	Pyrazolo[1,5-a][1,3,5]triazine and pyrazolo[1,5-a]pyrimidine derivatives as cdk inhibitors
WO2017052394A1 (en) *	2015-09-23	2017-03-30	Uniwersytet Jagielloński	Imidazopyridine compounds and their use as 5-ht6 receptor ligands
ES2765738T3 (es)	2015-11-02	2020-06-10	Janssen Pharmaceutica Nv	Compuesto de [1,2,4]triazolo[1,5-a]pirimidin-7-ilo
EP3535269B1 (en)	2016-11-02	2020-12-09	Janssen Pharmaceutica NV	[1,2,4]triazolo[1,5-a]pyrimidine compounds as pde2 inhibitors
UA125302C2 (uk)	2016-11-02	2022-02-16	Янссен Фармацевтика Нв	Похідні [1,2,4]триазоло[1,5-a]піримідину як інгібітори pde2
KR20190067788A (ko)	2016-11-02	2019-06-17	얀센 파마슈티카 엔.브이.	Pde2 억제제로서의 [1,2,4]트리아졸로[1,5-a]피리미딘 화합물
WO2020224568A1 (en)	2019-05-05	2020-11-12	Qilu Regor Therapeutics Inc.	Cdk inhibitors
CN112142744A (zh) *	2019-06-28	2020-12-29	上海瑛派药业有限公司	取代的稠合杂芳双环化合物作为激酶抑制剂及其应用
KR20220140515A (ko)	2020-01-13	2022-10-18	버지 애널리틱스, 인크.	치환된 피라졸로-피리미딘 및 그의 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3907799A (en) *	1971-08-16	1975-09-23	Icn Pharmaceuticals	Xanthine oxidase inhibitors
US4921527A (en) *	1987-07-31	1990-05-01	E. I. Du Pont De Nemours And Company	Herbicidal sulfonamides
EP0368897A1 (en)	1987-07-31	1990-05-23	E.I. Du Pont De Nemours And Company	Herbicidal sulfonamides
DE3825043A1 (de)	1988-07-20	1990-02-15	Schering Ag	3-methylsulfonyl-pyrazolo(1,5-a)pyrimidin-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider, pflanzenwuchsregulierender und fungizider wirkung
US5571813A (en) *	1993-06-10	1996-11-05	Beiersdorf-Lilly Gmbh	Fused pyrimidine compounds and their use as pharmaceuticals
WO1997011075A1 (en)	1995-09-22	1997-03-27	Takeda Chemical Industries, Ltd.	Triazole compounds, their production and use
DZ2376A1 (fr)	1996-12-19	2002-12-28	Smithkline Beecham Plc	Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
JP2001506995A (ja)	1996-12-19	2001-05-29	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	Ｎ−ピペラジン−１−イルフェニル−ベンズアミド誘導体
JP2002511097A (ja)	1997-07-11	2002-04-09	スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー	５−ｈｔ▲下６▼レセプターアンタゴニストであるスルホンアミド誘導体およびその製造方法

1999
- 1999-02-24 US US09/256,927 patent/US6194410B1/en not_active Expired - Fee Related
- 1999-03-03 ES ES99102872T patent/ES2198095T3/es not_active Expired - Lifetime
- 1999-03-03 EP EP99102872A patent/EP0941994B1/en not_active Expired - Lifetime
- 1999-03-03 DK DK99102872T patent/DK0941994T3/da active
- 1999-03-03 DE DE69907784T patent/DE69907784T2/de not_active Expired - Fee Related
- 1999-03-03 AT AT99102872T patent/ATE240332T1/de not_active IP Right Cessation
- 1999-03-03 PT PT99102872T patent/PT941994E/pt unknown
- 1999-03-03 SI SI9930320T patent/SI0941994T1/xx unknown
- 1999-03-08 PE PE1999000183A patent/PE20000337A1/es not_active Application Discontinuation
- 1999-03-08 IL IL12886999A patent/IL128869A/xx not_active IP Right Cessation
- 1999-03-08 MA MA25485A patent/MA26612A1/fr unknown
- 1999-03-08 NZ NZ334526A patent/NZ334526A/xx unknown
- 1999-03-08 YU YU12099A patent/YU12099A/sh unknown
- 1999-03-08 CA CA002265095A patent/CA2265095C/en not_active Expired - Fee Related
- 1999-03-09 JP JP06114999A patent/JP3231288B2/ja not_active Expired - Fee Related
- 1999-03-09 AR ARP990100990A patent/AR016453A1/es unknown
- 1999-03-09 UY UY25419A patent/UY25419A1/es unknown
- 1999-03-09 SG SG1999001080A patent/SG78336A1/en unknown
- 1999-03-09 MY MYPI99000853A patent/MY119536A/en unknown
- 1999-03-10 TW TW088103692A patent/TW585865B/zh not_active IP Right Cessation
- 1999-03-10 PL PL99331875A patent/PL331875A1/xx unknown
- 1999-03-10 BR BR9901095-0A patent/BR9901095A/pt not_active Application Discontinuation
- 1999-03-10 KR KR1019990007881A patent/KR100313181B1/ko not_active Expired - Fee Related
- 1999-03-10 HU HU9900589A patent/HUP9900589A1/hu not_active Application Discontinuation
- 1999-03-10 NO NO19991150A patent/NO312297B1/no unknown
- 1999-03-10 ID IDP990198D patent/ID23575A/id unknown
- 1999-03-10 CZ CZ1999825A patent/CZ291514B6/cs not_active IP Right Cessation
- 1999-03-10 ZA ZA9901946A patent/ZA991946B/xx unknown
- 1999-03-10 RU RU99105137/04A patent/RU2218340C2/ru active
- 1999-03-11 AU AU20383/99A patent/AU752408B2/en not_active Ceased
- 1999-03-11 TR TR1999/00531A patent/TR199900531A3/tr unknown
- 1999-03-11 CN CN99105964A patent/CN1118468C/zh not_active Expired - Fee Related
- 1999-03-11 HR HR990077A patent/HRP990077B1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1023343A1 (en)	2000-09-08
TR199900531A2 (xx)	1999-10-21
HRP990077B1 (en)	2003-08-31
KR19990077741A (ko)	1999-10-25
JP2000186090A (ja)	2000-07-04
PT941994E (pt)	2003-09-30
BR9901095A (pt)	2000-05-02
NO991150L (no)	1999-09-13
DE69907784D1 (de)	2003-06-18
AU752408B2 (en)	2002-09-19
HUP9900589A1 (hu)	2000-03-28
UY25419A1 (es)	2001-11-30
ID23575A (id)	2000-05-04
CN1236780A (zh)	1999-12-01
PE20000337A1 (es)	2000-05-13
CA2265095A1 (en)	1999-09-11
US6194410B1 (en)	2001-02-27
ZA991946B (en)	1999-09-13
IL128869A0 (en)	2000-01-31
ES2198095T3 (es)	2004-01-16
NO991150D0 (no)	1999-03-10
CZ82599A3 (cs)	1999-09-15
HRP990077A2 (en)	2000-02-29
DE69907784T2 (de)	2004-03-25
SI0941994T1 (en)	2003-10-31
CZ291514B6 (cs)	2003-03-12
AR016453A1 (es)	2001-07-04
CA2265095C (en)	2008-07-22
NZ334526A (en)	2000-07-28
PL331875A1 (en)	1999-09-13
HU9900589D0 (en)	1999-05-28
CN1118468C (zh)	2003-08-20
EP0941994A1 (en)	1999-09-15
MA26612A1 (fr)	2004-12-20
YU12099A (sh)	2000-10-30
TW585865B (en)	2004-05-01
ATE240332T1 (de)	2003-05-15
EP0941994B1 (en)	2003-05-14
TR199900531A3 (tr)	1999-10-21
AU2038399A (en)	1999-09-23
RU2218340C2 (ru)	2003-12-10
MY119536A (en)	2005-06-30
JP3231288B2 (ja)	2001-11-19
IL128869A (en)	2003-09-17
KR100313181B1 (ko)	2001-11-05
NO312297B1 (no)	2002-04-22
SG78336A1 (en)	2001-02-20

Publication	Publication Date	Title
DK0941994T3 (da)	2003-09-08	Pyrazolopyrimidiner og pyrazolotriaziner med 5-HT6 receptoraffinitet
DE69911378D1 (de)	2003-10-23	Fluorierte ionomere und verwendung davon
DK1454907T3 (da)	2009-03-09	Quninazolin og pyridopyrmidin-derivativer
DE59703646D1 (de)	2001-07-05	Messkugel-reflektor
FI973816A0 (fi)	1997-09-26	Polypropen med hoeg smaeltstyrka
NO992838D0 (no)	1999-06-10	Benzotiofenkarboksamid-derivater og PGD2 antagonister omfattende disse
DE59701856D1 (de)	2000-07-13	Kugelgelenk
DK0915880T3 (da)	2008-02-11	Azolotriaziner og pyrimidiner
DK0906301T3 (da)	2003-02-10	Benzofurylderivater og anvendelsen deraf
DE69726837D1 (de)	2004-01-29	Kautschukzusammensetzung mit verminderter wärmeentwicklung und walzen
DE69736457D1 (de)	2006-09-21	Interatomares messverfahren
NO20004274D0 (no)	2000-08-25	Proteaseaktivert reseptor 4 og anvendelse derav
NO986174L (no)	1999-07-05	Triazinderivater og anvendelse derav
DE69916694D1 (de)	2004-06-03	2-Hydroxy-5-methyl-hexan-3-on und 3-hydroxy-5-methyl-hexan-2-on
DK1025100T3 (da)	2002-05-06	3-substituerede tetrahydropyridopyrimidinonderivater, fremstilling og anvendelsen heraf
FI962419A0 (fi)	1996-06-11	Ringoskillator med hoeg hastighet
DK1140952T3 (da)	2004-01-12	Phosphororganiske forbindelser og anvendelse heraf
NO20001718D0 (no)	2000-04-03	Benzen-fusjonerte heterocykliske derivater og anvendelse derav
NO991372L (no)	2000-02-21	Trinn med reflektorer
IT1288298B1 (it)	1998-09-16	Sedia scolastica e banco scolastico
FI962780L (fi)	1998-01-09	Syöttötuoli-porrasjakkara
DK39696A (da)	1997-10-04	Opblæselig konstruktion
DE69628756D1 (de)	2003-07-24	Kombinierte longitudinale und transversale Spurnachführung
DE59704118D1 (de)	2001-08-30	Sitzeinrichtung
NO20000038L (no)	2000-03-08	Benzodiazepinderivater og tilsvarende anvendelse og sammensetning