DK0974356T3 - Tabletter omfattende en kombination af metformin og glibenclamid - Google Patents

Tabletter omfattende en kombination af metformin og glibenclamid

Info

Publication number
DK0974356T3
DK0974356T3 DK98401781T DK98401781T DK0974356T3 DK 0974356 T3 DK0974356 T3 DK 0974356T3 DK 98401781 T DK98401781 T DK 98401781T DK 98401781 T DK98401781 T DK 98401781T DK 0974356 T3 DK0974356 T3 DK 0974356T3
Authority
DK
Denmark
Prior art keywords
glibenclamide
metformin
tablets
combination
Prior art date
Application number
DK98401781T
Other languages
Danish (da)
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0974356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of DK0974356T3 publication Critical patent/DK0974356T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98401781T 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid DK0974356T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (fr) 1998-07-15 1998-07-15 Comprimés contenant une combinaison de glibenclamide et de metformine

Publications (1)

Publication Number Publication Date
DK0974356T3 true DK0974356T3 (da) 2003-10-27

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98401781T DK0974356T3 (da) 1998-07-15 1998-07-15 Tabletter omfattende en kombination af metformin og glibenclamid

Country Status (27)

Country Link
US (2) US6303146B1 (fr)
EP (4) EP0974356B1 (fr)
JP (2) JP2002520371A (fr)
KR (2) KR20040053177A (fr)
CN (2) CN1146427C (fr)
AP (1) AP1450A (fr)
AR (2) AR013052A1 (fr)
AT (1) ATE250418T1 (fr)
AU (2) AU753604B2 (fr)
BR (1) BR9906600A (fr)
CA (1) CA2303537C (fr)
DE (1) DE69818444T2 (fr)
DK (1) DK0974356T3 (fr)
DZ (1) DZ2846A1 (fr)
ES (1) ES2206868T3 (fr)
ID (1) ID25784A (fr)
MA (1) MA24930A1 (fr)
MY (1) MY129552A (fr)
NZ (1) NZ503248A (fr)
OA (1) OA11400A (fr)
PT (1) PT974356E (fr)
RU (2) RU2226396C2 (fr)
SI (1) SI0974356T1 (fr)
TW (2) TW555560B (fr)
UY (1) UY25611A1 (fr)
WO (1) WO2000003742A2 (fr)
ZA (1) ZA200001159B (fr)

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FR2816840B1 (fr) 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
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US20050271737A1 (en) * 2001-06-07 2005-12-08 Chinea Vanessa I Application of a bioactive agent to a substrate
US7767249B2 (en) * 2001-06-07 2010-08-03 Hewlett-Packard Development Company, L.P. Preparation of nanoparticles
US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
ATE378054T1 (de) * 2001-07-30 2007-11-15 Mitsubishi Pharma Corp Mittel zu linderung von hyperglykämie nach dem essen
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
ITFI20010230A1 (it) * 2001-11-29 2003-05-29 Menarini Int Operations Lu Sa Composizioni farmaceutiche per il trattamento del diabete mellito di tipo ii
US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
ES2284829T3 (es) * 2002-01-25 2007-11-16 Laboratorios Silanes, S.A. De C.V. Composicion farmaceutica que se usa para controlar la glucosa en sangre en pacientes con diabetes de tipo 2.
PT1476138E (pt) * 2002-02-21 2012-02-14 Valeant Internat Barbados Srl Formulações de libertação modificada de pelo menos uma forma de tramadol
US20030187074A1 (en) * 2002-03-04 2003-10-02 Javed Hussain Oral compositions for treatment of diabetes
US20030219482A1 (en) * 2002-03-21 2003-11-27 Chaudhari Sunil Sudhakar Multiparticulate compositions for once-a-day administration
MXPA04009968A (es) 2002-04-09 2004-12-13 Flamel Tech Sa Formulacion farmaceutica oral bajo forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de principio (s) activo (s).
DE60323474D1 (de) 2002-04-09 2008-10-23 Flamel Tech Sa Orale pharmazeutische formulierung in form einer wässrigen suspension von mikrokapseln zur modifizierten freisetzung von amoxicillin
WO2003105809A1 (fr) 2002-06-17 2003-12-24 Themis Laboratories Private Limited Comprimes multicouche contenant des thiazolidinediones et des biguanides et procedes de production desdits comprimes
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
US20060002998A1 (en) * 2002-11-15 2006-01-05 Anupam Trehan Pharmaceutical dosage forms of biguanide-sulfonylurea combinations
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
AU2004229285A1 (en) * 2003-04-15 2004-10-28 Chugai Seiyaku Kabushiki Kaisha Remedy for diabetes
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
ATE540681T1 (de) 2006-06-26 2012-01-15 Amgen Inc Verfahren zur behandlung von atherosklerose
WO2008062273A2 (fr) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Forme posologique solide administration orale contenant une combinaison de médicaments antidiabétiques
UA98799C2 (ru) 2007-07-19 2012-06-25 Такеда Фармасьютикал Компани Лимитед Твердый препарат, включающий алоглиптин и гидрохлорид метформина
NZ582794A (en) 2007-07-26 2012-09-28 Amgen Inc Modified lecithin-cholesterol acyltransferase enzymes
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
WO2011135106A1 (fr) * 2010-04-26 2011-11-03 Smart Pharma Solutions, S.L Granulé hautement dispersible pour la préparation de formulations de substances actives de hautes doses et procédé d'obtention de celui-ci
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
CA2858572C (fr) 2011-12-08 2023-01-17 Amgen Inc. Proteines liant un antigene lcat humain et leur utilisation en therapie
WO2013090452A1 (fr) * 2011-12-12 2013-06-20 Orbis Biosciences, Inc. Formulations de particules à libération prolongée
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (fr) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugués pour le traitement du diabète sucré
JP2023528565A (ja) 2020-04-01 2023-07-05 ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー.,エルティーディー. Glp-1受容体アゴニストの結晶形aおよびその調製法
EP4141008A4 (fr) 2020-04-01 2024-04-17 Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. Sel d'acide pharmaceutiquement acceptable de base libre d'agoniste du récepteur glp-1, et son procédé de préparation
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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Also Published As

Publication number Publication date
DE69818444D1 (de) 2003-10-30
EP2269613A2 (fr) 2011-01-05
CN1275082A (zh) 2000-11-29
CN1146427C (zh) 2004-04-21
JP2002520371A (ja) 2002-07-09
RU2226396C2 (ru) 2004-04-10
EP0974356A1 (fr) 2000-01-26
WO2000003742A3 (fr) 2000-04-20
MA24930A1 (fr) 2000-04-01
ID25784A (id) 2000-11-02
KR20010030603A (ko) 2001-04-16
ES2206868T3 (es) 2004-05-16
USRE38629E1 (en) 2004-10-19
NZ503248A (en) 2002-09-27
TW555560B (en) 2003-10-01
KR100478347B1 (ko) 2005-03-23
ZA200001159B (en) 2001-05-31
BR9906600A (pt) 2000-07-18
TWI245632B (en) 2005-12-21
RU2286788C2 (ru) 2006-11-10
CA2303537A1 (fr) 2000-01-27
DZ2846A1 (fr) 2003-12-01
OA11400A (en) 2004-04-08
AP1450A (en) 2005-07-25
WO2000003742A2 (fr) 2000-01-27
AP2000001757A0 (en) 2000-03-31
UY25611A1 (es) 2000-08-21
DE69818444T2 (de) 2004-05-06
KR20040053177A (ko) 2004-06-23
JP2003292443A (ja) 2003-10-15
EP1011684A2 (fr) 2000-06-28
AU2003261560A1 (en) 2005-05-26
AR013052A1 (es) 2000-11-22
AU5417999A (en) 2000-02-07
AR065970A2 (es) 2009-07-15
EP1435240A2 (fr) 2004-07-07
CA2303537C (fr) 2005-12-06
EP1435240A3 (fr) 2009-08-12
EP0974356B1 (fr) 2003-09-24
ATE250418T1 (de) 2003-10-15
RU2003126257A (ru) 2005-02-27
EP2269613A3 (fr) 2012-10-17
PT974356E (pt) 2004-02-27
US6303146B1 (en) 2001-10-16
CN1486698A (zh) 2004-04-07
SI0974356T1 (en) 2003-12-31
AU753604B2 (en) 2002-10-24
MY129552A (en) 2007-04-30
TW200303208A (en) 2003-09-01

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