MA24930A1 - Forme posologique a usage oral comprenant une combinaison de metformine et de glibenclamide - Google Patents

Forme posologique a usage oral comprenant une combinaison de metformine et de glibenclamide

Info

Publication number
MA24930A1
MA24930A1 MA25681A MA25681A MA24930A1 MA 24930 A1 MA24930 A1 MA 24930A1 MA 25681 A MA25681 A MA 25681A MA 25681 A MA25681 A MA 25681A MA 24930 A1 MA24930 A1 MA 24930A1
Authority
MA
Morocco
Prior art keywords
glibenclamide
metformin
combination
dosage form
oral dosage
Prior art date
Application number
MA25681A
Other languages
English (en)
Inventor
Yves Bonhomme
Geoffrey Nicholson
Sarah J Nicholson
Gillian Cave
Original Assignee
Lipha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8235441&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA24930(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lipha filed Critical Lipha
Publication of MA24930A1 publication Critical patent/MA24930A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/64Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA PRÉSENTE INVENTION CONCERNE UNE FORME POSOLOGIQUE SOLIDE À USAGE ORAL COMPRENANT UNE COMBINAISON DE METFORMINE ET DE GLIBENCLAMIDE, DANS LAQUELLE LA TAILLE DU GLIBENCLAMIDE EST TELLE QUE LA BIODISPONIBILITÉ DU GLIBENCLAMIDE SOIT COMPARABLE À LA BIODDISPONIBILITÉ DU GLIBENCLAMIDE OBTENUE AVEC UNE ADMINISTRATION SÉPARÉE DE METFORMINE ET DE GLIBENCLAMIDE.
MA25681A 1998-07-15 1999-07-13 Forme posologique a usage oral comprenant une combinaison de metformine et de glibenclamide MA24930A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98401781A EP0974356B1 (fr) 1998-07-15 1998-07-15 Comprimés contenant une combinaison de glibenclamide et de metformine

Publications (1)

Publication Number Publication Date
MA24930A1 true MA24930A1 (fr) 2000-04-01

Family

ID=8235441

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25681A MA24930A1 (fr) 1998-07-15 1999-07-13 Forme posologique a usage oral comprenant une combinaison de metformine et de glibenclamide

Country Status (27)

Country Link
US (2) US6303146B1 (fr)
EP (4) EP0974356B1 (fr)
JP (2) JP2002520371A (fr)
KR (2) KR20040053177A (fr)
CN (2) CN1486698A (fr)
AP (1) AP1450A (fr)
AR (2) AR013052A1 (fr)
AT (1) ATE250418T1 (fr)
AU (2) AU753604B2 (fr)
BR (1) BR9906600A (fr)
CA (1) CA2303537C (fr)
DE (1) DE69818444T2 (fr)
DK (1) DK0974356T3 (fr)
DZ (1) DZ2846A1 (fr)
ES (1) ES2206868T3 (fr)
ID (1) ID25784A (fr)
MA (1) MA24930A1 (fr)
MY (1) MY129552A (fr)
NZ (1) NZ503248A (fr)
OA (1) OA11400A (fr)
PT (1) PT974356E (fr)
RU (2) RU2286788C2 (fr)
SI (1) SI0974356T1 (fr)
TW (2) TWI245632B (fr)
UY (1) UY25611A1 (fr)
WO (1) WO2000003742A2 (fr)
ZA (1) ZA200001159B (fr)

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US6586438B2 (en) * 1999-11-03 2003-07-01 Bristol-Myers Squibb Co. Antidiabetic formulation and method
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FR2816841B1 (fr) * 2000-11-22 2004-02-06 Lipha Nouvelles compositions pharmaceutiques a action antidiabetique et leur procede de preparation
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FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
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US8206753B2 (en) * 2001-06-20 2012-06-26 Metaproteomics, Llc Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
WO2003011308A1 (fr) * 2001-07-30 2003-02-13 Mitsubishi Pharma Corporation Medicaments destines a l'amelioration de l'hyperglycemie post-prandiale
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
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US7183321B2 (en) * 2001-12-17 2007-02-27 Bristol-Myers Squibb Company Antidiabetic formulation and method
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WO2003084518A2 (fr) 2002-04-09 2003-10-16 Flamel Technologies Suspension orale de microcapsules de principes actifs
ES2314227T7 (es) 2002-04-09 2012-11-19 Flamel Technologies Formulacion farmaceutica oral en forma de suspension acuosa de microcapsulas que permiten la liberacion modificada de amoxilicina.
EP1515701B1 (fr) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Procédé de fabrication de comprimés multicouches comprenant de la thiazolidinedione et du biguanide
US7445796B2 (en) * 2002-08-19 2008-11-04 L. Perrigo Company Pharmaceutically active particles of a monomodal particle size distribution and method
CN1729005A (zh) * 2002-11-15 2006-02-01 兰贝克赛实验室有限公司 含双胍-磺酰脲类组合的药物剂型
FR2853831A1 (fr) * 2003-03-05 2004-10-22 Usv Ltd Forme posologique solide a usage oral de metformine et de glyburide et son procede de preparation
US7662366B2 (en) * 2003-04-15 2010-02-16 Chugai Seiyaku Kabushiki Kaisha Method of preventing β cell disruption in pancreatic Langerhans' islets
US20060121108A1 (en) * 2004-12-02 2006-06-08 Prasad C K System and method for producing a directly compressible, high-potency formulation of metformin hydrochloride
CN100341495C (zh) * 2004-12-29 2007-10-10 三九医药股份有限公司 格列本脲固体分散体、口服组合物及其制备方法
KR100760430B1 (ko) * 2004-12-31 2007-10-04 한미약품 주식회사 당뇨병 치료제의 경구 투여용 서방성 복합 제제 및 이의제조 방법
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
US8529537B2 (en) * 2005-08-05 2013-09-10 Kimberly-Clark Worldwide, Inc. Absorbent article with enclosures
MXPA05009633A (es) * 2005-09-08 2007-03-07 Silanes Sa De Cv Lab Composicion farmaceutica estable de glimepirida de liberacion inmediata y metformina de liberacion prolongada.
AU2007265475B2 (en) 2006-06-26 2010-08-19 Amgen Inc. Methods for treating atherosclerosis
WO2008062273A2 (fr) * 2006-11-20 2008-05-29 Cadila Pharmaceuticals Limited Forme posologique solide administration orale contenant une combinaison de médicaments antidiabétiques
CN101801351B (zh) 2007-07-19 2012-12-12 武田药品工业株式会社 包含阿格列汀和盐酸二甲双胍的固体制剂
PT2489731E (pt) 2007-07-26 2014-09-15 Amgen Inc Enzimas aciltransferase de lecitina-colesterol modificadas
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
WO2011135106A1 (fr) * 2010-04-26 2011-11-03 Smart Pharma Solutions, S.L Granulé hautement dispersible pour la préparation de formulations de substances actives de hautes doses et procédé d'obtention de celui-ci
RU2451506C1 (ru) 2011-06-02 2012-05-27 Сергей Юрьевич Лешков Комбинация для лечения сахарного диабета и его осложнений
WO2013086443A1 (fr) 2011-12-08 2013-06-13 Amgen Inc. Protéines agonistes de liaison à l'antigène lcat humain et leur utilisation thérapeutique
EP2790729A4 (fr) * 2011-12-12 2015-08-12 Orbis Biosciences Inc Formulations de particules à libération prolongée
CN104127424A (zh) * 2014-07-30 2014-11-05 沈阳药科大学 格列本脲衍生物及其制备方法和应用
CN105030793A (zh) * 2015-08-25 2015-11-11 瑞阳制药有限公司 二甲双胍格列本脲胶囊及其制备方法
WO2019070109A1 (fr) * 2017-10-03 2019-04-11 Infinite Clinical Research International, S.A. De C.V. Triconjugués pour le traitement du diabète sucré
JP2023528726A (ja) 2020-04-01 2023-07-06 ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー.,エルティーディー. Glp1rアゴニスト遊離塩基の薬学的に許容される酸塩類およびその調製法
EP4130005A4 (fr) 2020-04-01 2024-04-24 Hangzhou Zhongmeihuadong Pharmaceutical Co., Ltd. Forme cristalline a d'antagoniste du récepteur glp-1 et son procédé de préparation
KR102484756B1 (ko) * 2020-11-13 2023-01-06 한국생산기술연구원 용해성 증대 및 취급용이성을 갖는 파우더 배지의 과립화 방법
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

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Also Published As

Publication number Publication date
BR9906600A (pt) 2000-07-18
USRE38629E1 (en) 2004-10-19
JP2002520371A (ja) 2002-07-09
RU2286788C2 (ru) 2006-11-10
ID25784A (id) 2000-11-02
JP2003292443A (ja) 2003-10-15
EP0974356A1 (fr) 2000-01-26
ES2206868T3 (es) 2004-05-16
EP2269613A2 (fr) 2011-01-05
ATE250418T1 (de) 2003-10-15
AP1450A (en) 2005-07-25
CN1486698A (zh) 2004-04-07
TW200303208A (en) 2003-09-01
CA2303537C (fr) 2005-12-06
EP1435240A3 (fr) 2009-08-12
OA11400A (en) 2004-04-08
KR20010030603A (ko) 2001-04-16
RU2003126257A (ru) 2005-02-27
EP2269613A3 (fr) 2012-10-17
AP2000001757A0 (en) 2000-03-31
EP0974356B1 (fr) 2003-09-24
CN1275082A (zh) 2000-11-29
NZ503248A (en) 2002-09-27
ZA200001159B (en) 2001-05-31
AR065970A2 (es) 2009-07-15
KR100478347B1 (ko) 2005-03-23
PT974356E (pt) 2004-02-27
AU753604B2 (en) 2002-10-24
CN1146427C (zh) 2004-04-21
EP1011684A2 (fr) 2000-06-28
MY129552A (en) 2007-04-30
DE69818444D1 (de) 2003-10-30
EP1435240A2 (fr) 2004-07-07
TW555560B (en) 2003-10-01
US6303146B1 (en) 2001-10-16
TWI245632B (en) 2005-12-21
WO2000003742A3 (fr) 2000-04-20
DK0974356T3 (da) 2003-10-27
RU2226396C2 (ru) 2004-04-10
SI0974356T1 (en) 2003-12-31
WO2000003742A2 (fr) 2000-01-27
UY25611A1 (es) 2000-08-21
AR013052A1 (es) 2000-11-22
DE69818444T2 (de) 2004-05-06
AU2003261560A1 (en) 2005-05-26
DZ2846A1 (fr) 2003-12-01
KR20040053177A (ko) 2004-06-23
CA2303537A1 (fr) 2000-01-27
AU5417999A (en) 2000-02-07

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