DK0983058T3 - Medicinske aerosolprodukter - Google Patents

Medicinske aerosolprodukter

Info

Publication number: DK0983058T3
Authority: DK; Denmark
Prior art keywords: ciclesonide; butyl; formulations; aerosol products; medical aerosol
Prior art date: 1997-05-21

Application number

DK98922409T

Other languages

English (en)

Inventor

Martin J Oliver

Kanu M Fatania

John S Scott

Helgert Muller

Original Assignee

Altana Pharma Ag

Minnesota Mining & Mfg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-05-21

Filing date

1998-05-18

Publication date

2003-11-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26311564&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0983058(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-05-21 Priority claimed from GBGB9710496.2A external-priority patent/GB9710496D0/en

1998-02-25 Priority claimed from GBGB9803990.2A external-priority patent/GB9803990D0/en

1998-05-18 Application filed by Altana Pharma Ag, Minnesota Mining & Mfg filed Critical Altana Pharma Ag

2003-11-24 Application granted granted Critical

2003-11-24 Publication of DK0983058T3 publication Critical patent/DK0983058T3/da

Links

239000000443 aerosol Substances 0.000 title 1
238000009472 formulation Methods 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 3
LUKZNWIVRBCLON-GXOBDPJESA-N Ciclesonide Chemical compound C1([C@H]2O[C@@]3([C@H](O2)C[C@@H]2[C@@]3(C[C@H](O)[C@@H]3[C@@]4(C)C=CC(=O)C=C4CC[C@H]32)C)C(=O)COC(=O)C(C)C)CCCCC1 LUKZNWIVRBCLON-GXOBDPJESA-N 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
229960003728 ciclesonide Drugs 0.000 abstract 2
LVGUZGTVOIAKKC-UHFFFAOYSA-N 1,1,1,2-tetrafluoroethane Chemical compound FCC(F)(F)F LVGUZGTVOIAKKC-UHFFFAOYSA-N 0.000 abstract 1
125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
239000002260 anti-inflammatory agent Substances 0.000 abstract 1
239000006184 cosolvent Substances 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
239000004615 ingredient Substances 0.000 abstract 1
-1 isobutanoyl Chemical group 0.000 abstract 1
125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
239000008249 pharmaceutical aerosol Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
239000003380 propellant Substances 0.000 abstract 1
125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
239000004094 surface-active agent Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/124—Aerosols; Foams characterised by the propellant
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Materials For Medical Uses (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Thermotherapy And Cooling Therapy Devices (AREA)
Steroid Compounds (AREA)

DK98922409T 1997-05-21 1998-05-18 Medicinske aerosolprodukter DK0983058T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9710496.2A GB9710496D0 (en)	1997-05-21	1997-05-21	Medicinal aerosol products
GBGB9803990.2A GB9803990D0 (en)	1998-02-25	1998-02-25	Medicinal aerosol products
PCT/US1998/010155 WO1998052542A1 (en)	1997-05-21	1998-05-18	Medicinal aerosol products

Publications (1)

Publication Number	Publication Date
DK0983058T3 true DK0983058T3 (da)	2003-11-24

Family

ID=26311564

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK98922409T DK0983058T3 (da)	1997-05-21	1998-05-18	Medicinske aerosolprodukter

Country Status (27)

Country	Link
US (1)	US6120752A (da)
EP (1)	EP0983058B1 (da)
JP (4)	JP2001526685A (da)
KR (1)	KR100527643B1 (da)
CN (1)	CN1149073C (da)
AT (1)	ATE245966T1 (da)
AU (1)	AU726835B2 (da)
BG (1)	BG64268B1 (da)
BR (1)	BR9809448A (da)
CA (1)	CA2290521C (da)
CZ (1)	CZ298253B6 (da)
DE (1)	DE69816811T2 (da)
DK (1)	DK0983058T3 (da)
EA (1)	EA002381B1 (da)
ES (1)	ES2205491T3 (da)
HU (1)	HU226694B1 (da)
IL (1)	IL132738A (da)
ME (1)	ME01631B (da)
NO (2)	NO327716B1 (da)
NZ (1)	NZ500874A (da)
PL (1)	PL191523B1 (da)
PT (1)	PT983058E (da)
RS (1)	RS49628B (da)
SK (1)	SK283930B6 (da)
TR (1)	TR199902863T2 (da)
UA (1)	UA58551C2 (da)
WO (1)	WO1998052542A1 (da)

Families Citing this family (35)

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US7101534B1 (en)	1991-12-18	2006-09-05	3M Innovative Properties Company	Suspension aerosol formulations
US7105152B1 (en)	1991-12-18	2006-09-12	3M Innovative Properties Company	Suspension aerosol formulations
US6315985B1 (en)	1999-06-18	2001-11-13	3M Innovative Properties Company	C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
AR026072A1 (es) *	1999-10-20	2002-12-26	Nycomed Gmbh	Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
AR026073A1 (es) *	1999-10-20	2002-12-26	Nycomed Gmbh	Composicion farmaceutica acuosa que contiene ciclesonida
GB0002798D0 (en) *	2000-02-09	2000-03-29	Glaxo Group Ltd	Actuator nozzle for metered dose inhaler
GB0208742D0 (en)	2002-04-17	2002-05-29	Bradford Particle Design Ltd	Particulate materials
GB0207899D0 (en) *	2002-04-05	2002-05-15	3M Innovative Properties Co	Formoterol and cielesonide aerosol formulations
US7582284B2 (en)	2002-04-17	2009-09-01	Nektar Therapeutics	Particulate materials
US20040235811A1 (en) *	2002-10-08	2004-11-25	Sepracor Inc.	Fatty acid modified forms of glucocorticoids
PT2277972T (pt) *	2002-10-25	2019-06-11	Honeywell Int Inc	Composições contendo olefinas substituídas por flúor
ES2312844T3 (es) *	2002-12-12	2009-03-01	Nycomed Gmbh	Medicamento de combinacion de r, r-formoterol y ciclesonida.
MY143936A (en) *	2003-03-27	2011-07-29	Nycomed Gmbh	Process for preparing crystalline ciclesonide with defined particle size
AU2004241746A1 (en) *	2003-05-22	2004-12-02	Nycomed Gmbh	Salmeterol and ciclesonide combination
AU2004246819A1 (en)	2003-06-13	2004-12-23	Nycomed Gmbh	Formoterol and ciclesonide combination
WO2005025578A1 (en) *	2003-09-16	2005-03-24	Altana Pharma Ag	Use of ciclesonide for the treatment of respiratory diseases
GB2406283B (en)	2003-09-24	2006-04-05	Altana Pharma Ag	Compliance monitor and method
US9308199B2 (en)	2004-04-29	2016-04-12	Honeywell International Inc.	Medicament formulations
AR041873A1 (es) *	2003-10-30	2005-06-01	Pablo Cassara Srl Lab	Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
PE20050941A1 (es)	2003-12-16	2005-11-08	Nycomed Gmbh	Suspensiones acuosas de ciclesonida para nebulizacion
US20050153946A1 (en) *	2003-12-24	2005-07-14	Collegium Pharmaceuticals, Inc.	Temperature-stable formulations, and methods of development thereof
JP2007533706A (ja) *	2004-04-20	2007-11-22	ニコメッドゲゼルシャフトミットベシュレンクテルハフツング	喫煙患者における呼吸器疾患の治療のためのシクレソニドの使用
CA2579007A1 (en) *	2004-09-10	2006-03-16	Altana Pharma Ag	Ciclesonide and syk inhibitor combination and methods of use thereof
WO2006101882A2 (en) *	2005-03-16	2006-09-28	Honeywell International Inc.	Medicament delivery formulations, devices and methods
WO2007068007A1 (en) *	2005-12-07	2007-06-14	Harm Benjamin Steyn	Use of a disinfectant for treating respiratory tract infections
PL2425820T3 (pl)	2007-02-11	2015-08-31	Map Pharmaceuticals Inc	Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
US20100120737A1 (en) *	2008-11-10	2010-05-13	Martin Feth	Amorphous ciclesonide
ES2471145T3 (es) *	2009-03-09	2014-06-25	Mikasa Seiyaku Co,. Ltd.	Compuesto esteroide
WO2011135585A2 (en)	2010-04-28	2011-11-03	Cadila Healthcare Limited	Aqueous pharmaceutical solution of ciclesonide
KR20180028563A (ko) *	2010-10-12	2018-03-16	시플라 리미티드	약학 조성물
WO2013024070A1 (en)	2011-08-18	2013-02-21	Nycomed Gmbh	Pharmaceutical aerosol product for administration by oral or nasal inhalation
CN102335132A (zh) *	2011-10-12	2012-02-01	中山大学	一种细辛脑吸入气雾剂及其制备方法
WO2013114371A1 (en)	2012-02-01	2013-08-08	Protalix Ltd.	Dry powder formulations of dnase i
WO2013132497A1 (en)	2012-03-07	2013-09-12	Advanced Inhilation Therapies (Ait) Ltd.	Inhalation of nitric oxide for treating respiratory diseases
US20170304459A1 (en)	2014-10-10	2017-10-26	Alnylam Pharmaceuticals, Inc.	Methods and compositions for inhalation delivery of conjugated oligonucleotide

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DE4003272A1 (de) *	1990-02-03	1991-08-08	Boehringer Ingelheim Kg	Neue treibgasmischungen und ihre verwendung in arzneimittelzubereitungen
JPH05505824A (ja) *	1990-03-23	1993-08-26	ミネソタ　マイニング　アンド　マニュファクチャリング　カンパニー	所定投与量エアロゾル製剤の製造のための可溶性弗素界面活性剤の使用
GR1001529B (el) *	1990-09-07	1994-03-31	Elmuquimica Farm Sl	Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
ATE114112T1 (de) *	1990-10-18	1994-12-15	Minnesota Mining & Mfg	Aerosolzubereitung, die beclometason 17,21- dipropionat enthält.
IL104068A (en) *	1991-12-12	1998-10-30	Glaxo Group Ltd	Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
US5653962A (en) *	1991-12-12	1997-08-05	Glaxo Group Limited	Aerosol formulations containing P134a and particulate medicaments
US5474758A (en) *	1993-07-28	1995-12-12	Minnesota Mining And Manufacturing Company	Seals for use in an aerosol delivery device
EP0735884B1 (en) *	1993-12-20	2000-04-26	Minnesota Mining And Manufacturing Company	Flunisolide aerosol formulations
DE19541689A1 (de) *	1994-11-14	1996-05-15	Byk Gulden Lomberg Chem Fab	Kombinationsarzneimittel
US5653961A (en) *	1995-03-31	1997-08-05	Minnesota Mining And Manufacturing Company	Butixocort aerosol formulations in hydrofluorocarbon propellant
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1998
- 1998-05-13 US US09/076,958 patent/US6120752A/en not_active Expired - Lifetime
- 1998-05-18 BR BR9809448-3A patent/BR9809448A/pt not_active Application Discontinuation
- 1998-05-18 HU HU0002691A patent/HU226694B1/hu active Protection Beyond IP Right Term
- 1998-05-18 NZ NZ500874A patent/NZ500874A/en not_active IP Right Cessation
- 1998-05-18 TR TR1999/02863T patent/TR199902863T2/xx unknown
- 1998-05-18 CZ CZ0412499A patent/CZ298253B6/cs not_active IP Right Cessation
- 1998-05-18 ES ES98922409T patent/ES2205491T3/es not_active Expired - Lifetime
- 1998-05-18 RS YUP-598/99A patent/RS49628B/sr unknown
- 1998-05-18 WO PCT/US1998/010155 patent/WO1998052542A1/en not_active Ceased
- 1998-05-18 CA CA002290521A patent/CA2290521C/en not_active Expired - Lifetime
- 1998-05-18 AU AU74962/98A patent/AU726835B2/en not_active Expired
- 1998-05-18 DK DK98922409T patent/DK0983058T3/da active
- 1998-05-18 EA EA199900991A patent/EA002381B1/ru not_active IP Right Cessation
- 1998-05-18 CN CNB98805261XA patent/CN1149073C/zh not_active Expired - Lifetime
- 1998-05-18 IL IL13273898A patent/IL132738A/en not_active IP Right Cessation
- 1998-05-18 PL PL336885A patent/PL191523B1/pl unknown
- 1998-05-18 KR KR10-1999-7010773A patent/KR100527643B1/ko not_active Expired - Lifetime
- 1998-05-18 DE DE69816811T patent/DE69816811T2/de not_active Expired - Lifetime
- 1998-05-18 EP EP98922409A patent/EP0983058B1/en not_active Expired - Lifetime
- 1998-05-18 JP JP55049498A patent/JP2001526685A/ja active Pending
- 1998-05-18 ME MEP-1999-598A patent/ME01631B/me unknown
- 1998-05-18 UA UA99116244A patent/UA58551C2/uk unknown
- 1998-05-18 AT AT98922409T patent/ATE245966T1/de active
- 1998-05-18 SK SK1576-99A patent/SK283930B6/sk not_active IP Right Cessation
- 1998-05-18 PT PT98922409T patent/PT983058E/pt unknown
1999
- 1999-11-18 NO NO995667A patent/NO327716B1/no not_active IP Right Cessation
- 1999-11-19 BG BG103902A patent/BG64268B1/bg unknown
2009
- 2009-10-26 NO NO2009024C patent/NO2009024I2/no unknown
2010
- 2010-12-03 JP JP2010270854A patent/JP2011102301A/ja not_active Withdrawn
2014
- 2014-09-16 JP JP2014187710A patent/JP6087882B2/ja not_active Expired - Lifetime
2016
- 2016-05-19 JP JP2016100499A patent/JP6178459B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
SK283930B6 (sk)	2004-05-04
KR20010012810A (ko)	2001-02-26
JP2016169222A (ja)	2016-09-23
RS49628B (sr)	2007-08-03
PL336885A1 (en)	2000-07-17
SK157699A3 (en)	2000-05-16
EP0983058B1 (en)	2003-07-30
CN1149073C (zh)	2004-05-12
UA58551C2 (uk)	2003-08-15
BR9809448A (pt)	2000-06-20
PT983058E (pt)	2003-12-31
HK1027027A1 (en)	2001-01-05
CN1257421A (zh)	2000-06-21
NZ500874A (en)	2001-09-28
CZ298253B6 (cs)	2007-08-08
JP2011102301A (ja)	2011-05-26
CA2290521C (en)	2006-10-10
BG64268B1 (bg)	2004-08-31
JP2015024999A (ja)	2015-02-05
NO2009024I2 (no)	2010-08-16
JP6178459B2 (ja)	2017-08-09
NO327716B1 (no)	2009-09-14
AU726835B2 (en)	2000-11-23
JP6087882B2 (ja)	2017-03-01
ES2205491T3 (es)	2004-05-01
BG103902A (en)	2000-05-31
HUP0002691A2 (hu)	2001-02-28
CZ412499A3 (cs)	2000-02-16
NO995667L (no)	1999-11-18
ME01631B (me)	2007-08-03
IL132738A0 (en)	2001-03-19
US6120752A (en)	2000-09-19
JP2001526685A (ja)	2001-12-18
EA002381B1 (ru)	2002-04-25
NO995667D0 (no)	1999-11-18
EP0983058A1 (en)	2000-03-08
IL132738A (en)	2004-06-20
WO1998052542A1 (en)	1998-11-26
TR199902863T2 (xx)	2000-05-22
AU7496298A (en)	1998-12-11
CA2290521A1 (en)	1998-11-26
ATE245966T1 (de)	2003-08-15
HUP0002691A3 (en)	2001-04-28
PL191523B1 (pl)	2006-06-30
EA199900991A1 (ru)	2000-08-28
KR100527643B1 (ko)	2005-11-15
HU226694B1 (en)	2009-06-29
DE69816811D1 (de)	2003-09-04
NO2009024I1 (no)	2009-10-26
YU59899A (sh)	2002-06-19
DE69816811T2 (de)	2004-04-15

Publication	Publication Date	Title
NO995667D0 (no)	1999-11-18	Medisinske aerosolprodukter
DE60126599D1 (de)	2007-03-29	Cannabis enthaltende pharmazeutische zusammensetzungen
ATE401056T1 (de)	2008-08-15	Formoterol und ciclesonid aerosol-formulierungen
DK1303258T3 (da)	2007-01-22	Hidtil ukendte aerosolformuleringer, der indeholder et polært, floureret molekyle
BR9916829A (pt)	2001-10-23	Formulações aerossóis farmacêuticas contendo fluoroalcanos, budesonida e formoterol
NZ240237A (en)	1994-06-27	An aerosol formulation (free of surfactant) for treatment of asthma comprising: a hydrofluorocarbon propellant, ethanol, and beclomethasone 17,21 dipropionate; preparation thereof
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KR970706021A (ko)	1997-11-03	N-치환-o-톨루이딘유도체로 이루어진 약용배합제 및 경피흡수형제제(MEDICINAL ADJUVANTS CONSISTIONG OF AN N-SUBSTITUED-o-TOLUIDING DERIVANTIVE, AND PERCUTANEOUSLY ABSORBALE PREPARATIONS COMPRISING THE ADJUVANTS)
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