DK0988862T3 - Formulering indeholdende et antigen, en TH-1 inducerende adjuvant og en sparsomt vandoplöselig aminosyre til brug ved immunisering - Google Patents
Formulering indeholdende et antigen, en TH-1 inducerende adjuvant og en sparsomt vandoplöselig aminosyre til brug ved immuniseringInfo
- Publication number
- DK0988862T3 DK0988862T3 DK99307406T DK99307406T DK0988862T3 DK 0988862 T3 DK0988862 T3 DK 0988862T3 DK 99307406 T DK99307406 T DK 99307406T DK 99307406 T DK99307406 T DK 99307406T DK 0988862 T3 DK0988862 T3 DK 0988862T3
- Authority
- DK
- Denmark
- Prior art keywords
- antigen
- amino acid
- immunization
- formulation containing
- soluble amino
- Prior art date
Links
- 239000002671 adjuvant Substances 0.000 title abstract 2
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 230000001939 inductive effect Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 230000003053 immunization Effects 0.000 title 1
- 238000002649 immunization Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9820525.5A GB9820525D0 (en) | 1998-09-21 | 1998-09-21 | Formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0988862T3 true DK0988862T3 (da) | 2006-12-27 |
Family
ID=10839197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99307406T DK0988862T3 (da) | 1998-09-21 | 1999-09-17 | Formulering indeholdende et antigen, en TH-1 inducerende adjuvant og en sparsomt vandoplöselig aminosyre til brug ved immunisering |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6440426B1 (da) |
| EP (1) | EP0988862B1 (da) |
| JP (2) | JP4743928B2 (da) |
| KR (1) | KR100642877B1 (da) |
| AT (1) | ATE346610T1 (da) |
| AU (1) | AU766251B2 (da) |
| CA (1) | CA2282779C (da) |
| DE (1) | DE69934179T2 (da) |
| DK (1) | DK0988862T3 (da) |
| ES (1) | ES2277413T3 (da) |
| GB (2) | GB9820525D0 (da) |
| NZ (1) | NZ337885A (da) |
| PT (1) | PT988862E (da) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6380376B1 (en) * | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| GB9706957D0 (en) | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| CA2396237A1 (en) * | 2000-01-07 | 2001-07-19 | Jacob Gabriel Michael | Selective activation of a th1 or th2 lymphocyte regulated immune response |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
| US6680059B2 (en) * | 2000-08-29 | 2004-01-20 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| US6858590B2 (en) * | 2000-08-17 | 2005-02-22 | Tripep Ab | Vaccines containing ribavirin and methods of use thereof |
| CN100400101C (zh) * | 2000-08-17 | 2008-07-09 | 特里帕普股份公司 | 包含病毒唑的疫苗及其使用方法 |
| US7022830B2 (en) * | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
| DE60139944D1 (de) * | 2000-10-12 | 2009-10-29 | Genentech Inc | Niederviskose konzentrierte proteinformulierungen |
| US8703126B2 (en) | 2000-10-12 | 2014-04-22 | Genentech, Inc. | Reduced-viscosity concentrated protein formulations |
| ATE363522T1 (de) * | 2001-01-30 | 2007-06-15 | Schwan Stabilo Schwanhaeusser | Markierungsflüssigkeit |
| DE10125731A1 (de) * | 2001-05-17 | 2003-03-06 | A I D Autoimmun Diagnostika Gm | Darreichungsform von immunologischen Wirkstoffen |
| US20050158303A1 (en) * | 2003-04-04 | 2005-07-21 | Genentech, Inc. | Methods of treating IgE-mediated disorders comprising the administration of high concentration anti-IgE antibody formulations |
| PT1610820E (pt) * | 2003-04-04 | 2010-12-16 | Novartis Ag | Formulações de elevada concentração de anticorpos e proteínas |
| US8333976B2 (en) * | 2003-08-28 | 2012-12-18 | Sandor Sipka | Processes for inhibiting development of allergic disease |
| WO2006079989A2 (en) * | 2005-01-28 | 2006-08-03 | North-West University | Lipid and nitrous oxide combination as adjuvant for the enhancement of the efficacy of vaccines |
| EP1888751A2 (en) * | 2005-05-25 | 2008-02-20 | Tripep Ab | A hepatitis c virus non-structural ns3/4a fusion gene |
| WO2009022236A2 (en) | 2007-08-16 | 2009-02-19 | Tripep Ab | Immunogen platform |
| WO2009130588A2 (en) * | 2008-04-22 | 2009-10-29 | Tripep Ab | Immunogen platform |
| PE20120359A1 (es) * | 2009-03-06 | 2012-04-13 | Genentech Inc | Formulacion con anticuerpo |
| PT2542257T (pt) | 2010-03-01 | 2017-10-09 | Bayer Healthcare Llc | Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi) |
| GB201106802D0 (en) | 2011-04-21 | 2011-06-01 | Allergy Therapeutics Ltd | Process for preparing vaccine composition |
| US8613919B1 (en) | 2012-08-31 | 2013-12-24 | Bayer Healthcare, Llc | High concentration antibody and protein formulations |
| US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
| CN105530953A (zh) * | 2013-10-03 | 2016-04-27 | 日东电工株式会社 | 注射疫苗组合物 |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1128637A (en) | 1966-09-13 | 1968-09-25 | Beecham Group Ltd | Influenza vaccine |
| US3541201A (en) * | 1968-12-18 | 1970-11-17 | Ethan Alan Brown | Novel sodium chloride encapsulated injectionable substances |
| GB1377074A (en) | 1971-07-13 | 1974-12-11 | Beecham Group Ltd | Process for preparing injectable compositions |
| GB1492973A (en) | 1974-02-16 | 1977-11-23 | Beecham Group Ltd | Process for preparing injectable compositions |
| US4070455A (en) | 1974-02-16 | 1978-01-24 | Beecham Group Limited | Process for preparing injectable desensitizing compositions and products thereof in microparticle form |
| EP0182442B2 (en) | 1978-12-22 | 1996-04-03 | Biogen, Inc. | Recombinant DNA molecules and their method of production |
| US4258029A (en) | 1979-04-23 | 1981-03-24 | Connaught Laboratories Limited | Synthetic adjuvants for stimulation of antigenic responses |
| US4987237A (en) | 1983-08-26 | 1991-01-22 | Ribi Immunochem Research, Inc. | Derivatives of monophosphoryl lipid A |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5244663A (en) * | 1987-01-28 | 1993-09-14 | Medibrevex | Therapeutic method against allergy |
| FR2621916B1 (fr) * | 1987-10-19 | 1990-03-09 | Bioeurope | Derives de la l-tyrosine solubles dans l'eau et procede pour leur preparation |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| GB9106048D0 (en) | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccines |
| US5338543A (en) * | 1992-02-27 | 1994-08-16 | Ambico, Inc. | Thimerosal inactivated mycoplasma hyopneumoniae vaccine |
| FI944052A0 (fi) | 1992-03-03 | 1994-09-02 | Daiichi Seiyaku Co | Oraalinen rokote |
| DE69313134T2 (de) * | 1992-06-25 | 1998-02-26 | Smithkline Beecham Biolog | Adjuvantien enthaltende impfstoffzusammensetzung |
| CA2156525A1 (en) * | 1993-02-19 | 1994-09-01 | Susan Dillon | Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a |
| KR100310510B1 (ko) * | 1993-03-23 | 2002-07-04 | 장 스테판느 | 3-0-탈아세틸화모노포스포릴지질a를함유하는백신조성물 |
| US5958457A (en) * | 1993-04-22 | 1999-09-28 | Emisphere Technologies, Inc. | Compositions for the delivery of antigens |
| RU2160119C2 (ru) | 1993-05-25 | 2000-12-10 | Американ Цианамид Компани | Вакцинная композиция, содержащая белок респираторно-синцитиального вируса (варианты) |
| JPH09502604A (ja) | 1993-08-27 | 1997-03-18 | エンテリック リサーチ ラボラトリーズ インコーポレイテッド | Campylobacterjejuni抗原、並びにそれらの製造及び利用 |
| GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
| US5646115A (en) * | 1994-10-07 | 1997-07-08 | Heska Corporation | Ectoparasite saliva proteins and apparatus to collect such proteins |
| AU4977896A (en) | 1995-02-17 | 1996-09-04 | Immunotherapy, Inc. | Immunotherapy screening, prognosis, and treatment methods and compositions |
| GB9508785D0 (en) | 1995-04-29 | 1995-06-21 | Smithkline Beecham Plc | Novel compositions |
| US5762943A (en) * | 1996-05-14 | 1998-06-09 | Ribi Immunochem Research, Inc. | Methods of treating type I hypersensitivity using monophosphoryl lipid A |
| US5973128A (en) * | 1996-11-22 | 1999-10-26 | The Hospital For Sick Children Research And Development Lp | Glycolipid mimics and methods of use thereof |
| AU743114B2 (en) | 1997-04-01 | 2002-01-17 | Corixa Corporation | Aqueous immunologic adjuvant compositions of monophosphoryl lipid A |
| US6491919B2 (en) | 1997-04-01 | 2002-12-10 | Corixa Corporation | Aqueous immunologic adjuvant compostions of monophosphoryl lipid A |
| GB9706957D0 (en) * | 1997-04-05 | 1997-05-21 | Smithkline Beecham Plc | Formulation |
| WO1998058956A2 (en) | 1997-06-23 | 1998-12-30 | Ludwig Institute For Cancer Research | Methods for inducing an immune response involving prime-boost protocols |
| GB9717953D0 (en) | 1997-08-22 | 1997-10-29 | Smithkline Beecham Biolog | Vaccine |
| GB9720585D0 (en) | 1997-09-26 | 1997-11-26 | Smithkline Beecham Biolog | Vaccine |
| WO1999024577A1 (en) | 1997-11-10 | 1999-05-20 | Statens Serum Institut | NUCLEIC ACID FRAGMENTS AND POLYPEPTIDE FRAGMENTS DERIVED FROM $i(M. TUBERCULOSIS) |
| GB9812613D0 (en) * | 1998-06-11 | 1998-08-12 | Smithkline Beecham Biolog | Vaccine |
| CA2330209A1 (en) | 1998-06-12 | 1999-12-23 | Smithkline Beecham Biologicals S.A. | Recombinant production of toxoplasma sag1 antigen |
| GB9820525D0 (en) | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
| US6734172B2 (en) | 1998-11-18 | 2004-05-11 | Pacific Northwest Research Institute | Surface receptor antigen vaccines |
| EP1031347B1 (en) | 1999-01-27 | 2002-04-17 | Idea Ag | Transnasal transport/immunisation with highly adaptable carriers |
| EP1154793B1 (en) | 1999-02-26 | 2010-09-15 | Novartis Vaccines and Diagnostics, Inc. | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
| GB9909077D0 (en) | 1999-04-20 | 1999-06-16 | Smithkline Beecham Biolog | Novel compositions |
| EE200100552A (et) | 1999-04-23 | 2002-12-16 | Pharmexa A/S | Meetod kasvuteguri IL-5 aktiivsuse in vivo mahasurumiseks, IL-5 analoog, seda kodeeriv nukleiinhappefragment ning kasutamine immunogeense kompositsiooni valmistamiseks |
| UA81216C2 (en) | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
| GB9924529D0 (en) | 1999-10-15 | 1999-12-15 | Smithkline Beecham Biolog | Novel compounds |
| GB0000891D0 (en) | 2000-01-14 | 2000-03-08 | Allergy Therapeutics Ltd | Formulation |
-
1998
- 1998-09-21 GB GBGB9820525.5A patent/GB9820525D0/en not_active Ceased
-
1999
- 1999-09-17 ES ES99307406T patent/ES2277413T3/es not_active Expired - Lifetime
- 1999-09-17 PT PT99307406T patent/PT988862E/pt unknown
- 1999-09-17 KR KR1019990040180A patent/KR100642877B1/ko not_active Expired - Lifetime
- 1999-09-17 NZ NZ337885A patent/NZ337885A/xx not_active IP Right Cessation
- 1999-09-17 DK DK99307406T patent/DK0988862T3/da active
- 1999-09-17 AT AT99307406T patent/ATE346610T1/de active
- 1999-09-17 DE DE69934179T patent/DE69934179T2/de not_active Expired - Lifetime
- 1999-09-17 AU AU48777/99A patent/AU766251B2/en not_active Revoked
- 1999-09-17 GB GB9922121A patent/GB2341801B/en not_active Expired - Lifetime
- 1999-09-17 CA CA2282779A patent/CA2282779C/en not_active Expired - Lifetime
- 1999-09-17 EP EP99307406A patent/EP0988862B1/en not_active Expired - Lifetime
- 1999-09-17 JP JP26365299A patent/JP4743928B2/ja not_active Expired - Lifetime
- 1999-09-17 US US09/399,217 patent/US6440426B1/en not_active Expired - Lifetime
-
2002
- 2002-08-02 US US10/211,388 patent/US7815920B2/en not_active Expired - Fee Related
-
2010
- 2010-08-27 JP JP2010190949A patent/JP2010265330A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT988862E (pt) | 2007-01-31 |
| GB2341801A (en) | 2000-03-29 |
| GB9922121D0 (en) | 1999-11-17 |
| JP4743928B2 (ja) | 2011-08-10 |
| KR100642877B1 (ko) | 2006-11-13 |
| DE69934179D1 (de) | 2007-01-11 |
| DE69934179T2 (de) | 2007-04-19 |
| US6440426B1 (en) | 2002-08-27 |
| ATE346610T1 (de) | 2006-12-15 |
| EP0988862B1 (en) | 2006-11-29 |
| KR20000023273A (ko) | 2000-04-25 |
| CA2282779C (en) | 2011-02-01 |
| GB9820525D0 (en) | 1998-11-11 |
| EP0988862A2 (en) | 2000-03-29 |
| US20030007977A1 (en) | 2003-01-09 |
| JP2000103745A (ja) | 2000-04-11 |
| CA2282779A1 (en) | 2000-03-21 |
| GB2341801B (en) | 2003-10-29 |
| US7815920B2 (en) | 2010-10-19 |
| NZ337885A (en) | 2001-01-26 |
| EP0988862A3 (en) | 2001-06-20 |
| AU766251B2 (en) | 2003-10-09 |
| JP2010265330A (ja) | 2010-11-25 |
| AU4877799A (en) | 2000-06-08 |
| ES2277413T3 (es) | 2007-07-01 |
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