DK1015608T3 - Fremgangsmåder til undersögelse for receptoraktivitet og konstruktioner, som er anvendelige i sådanne fremgangsmåder - Google Patents

Fremgangsmåder til undersögelse for receptoraktivitet og konstruktioner, som er anvendelige i sådanne fremgangsmåder

Info

Publication number
DK1015608T3
DK1015608T3 DK98925260T DK98925260T DK1015608T3 DK 1015608 T3 DK1015608 T3 DK 1015608T3 DK 98925260 T DK98925260 T DK 98925260T DK 98925260 T DK98925260 T DK 98925260T DK 1015608 T3 DK1015608 T3 DK 1015608T3
Authority
DK
Denmark
Prior art keywords
methods
constructs useful
receptor activity
gpcr
activity
Prior art date
Application number
DK98925260T
Other languages
English (en)
Inventor
Lawrence S Barak
Marc G Caron
Stephen S Ferguson
Jie Zhang
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of DK1015608T3 publication Critical patent/DK1015608T3/da

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/91—Transferases (2.)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK98925260T 1997-06-05 1998-06-04 Fremgangsmåder til undersögelse for receptoraktivitet og konstruktioner, som er anvendelige i sådanne fremgangsmåder DK1015608T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/869,568 US5891646A (en) 1997-06-05 1997-06-05 Methods of assaying receptor activity and constructs useful in such methods

Publications (1)

Publication Number Publication Date
DK1015608T3 true DK1015608T3 (da) 2004-06-01

Family

ID=25353824

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98925260T DK1015608T3 (da) 1997-06-05 1998-06-04 Fremgangsmåder til undersögelse for receptoraktivitet og konstruktioner, som er anvendelige i sådanne fremgangsmåder

Country Status (10)

Country Link
US (5) US5891646A (da)
EP (2) EP1441032B1 (da)
AT (2) ATE482276T1 (da)
AU (1) AU759347B2 (da)
CA (1) CA2305810C (da)
DE (3) DE69841908D1 (da)
DK (1) DK1015608T3 (da)
ES (1) ES2182736T3 (da)
PT (1) PT1015608E (da)
WO (1) WO1998055635A1 (da)

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ATE482276T1 (de) 2010-10-15
AU759347B2 (en) 2003-04-10
ES2182736T3 (es) 2004-09-01
EP1441032B1 (en) 2010-09-22
WO1998055635A1 (en) 1998-12-10
AU7725598A (en) 1998-12-21
DE1015608T1 (de) 2002-11-14
CA2305810C (en) 2007-11-20
PT1015608E (pt) 2004-07-30
US20080261256A1 (en) 2008-10-23
US20040101887A1 (en) 2004-05-27
DE69822484D1 (de) 2004-04-22
DE69822484T2 (de) 2005-01-13
US5891646A (en) 1999-04-06
CA2305810A1 (en) 1998-12-10
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EP1015608A1 (en) 2000-07-05
WO1998055635A9 (en) 2003-05-08
DE69841908D1 (de) 2010-11-04
EP1441032A1 (en) 2004-07-28
US20060188944A1 (en) 2006-08-24
US6110693A (en) 2000-08-29
US7138240B2 (en) 2006-11-21
ES2182736T1 (es) 2003-03-16

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