DK1045906T3 - APO-2-ligand - Google Patents

APO-2-ligand

Info

Publication number
DK1045906T3
DK1045906T3 DK99903166T DK99903166T DK1045906T3 DK 1045906 T3 DK1045906 T3 DK 1045906T3 DK 99903166 T DK99903166 T DK 99903166T DK 99903166 T DK99903166 T DK 99903166T DK 1045906 T3 DK1045906 T3 DK 1045906T3
Authority
DK
Denmark
Prior art keywords
ligand
apo
antibodies
believed
nucleic acid
Prior art date
Application number
DK99903166T
Other languages
English (en)
Inventor
Avi J Ashkenazi
Robert F Kelley
Robert M Pitti
Ralph H Schwall
Mark T O'connel
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1045906T3 publication Critical patent/DK1045906T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK99903166T 1998-01-15 1999-01-15 APO-2-ligand DK1045906T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US788698A 1998-01-15 1998-01-15
US6053398A 1998-04-15 1998-04-15
PCT/US1999/001039 WO1999036535A1 (en) 1998-01-15 1999-01-15 Apo-2 ligand

Publications (1)

Publication Number Publication Date
DK1045906T3 true DK1045906T3 (da) 2009-02-16

Family

ID=26677483

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99903166T DK1045906T3 (da) 1998-01-15 1999-01-15 APO-2-ligand

Country Status (12)

Country Link
US (1) US6740739B1 (da)
EP (2) EP1045906B1 (da)
JP (2) JP2002508962A (da)
AT (1) ATE411385T1 (da)
AU (1) AU2325199A (da)
CA (1) CA2318029C (da)
CY (1) CY1108681T1 (da)
DE (1) DE69939732D1 (da)
DK (1) DK1045906T3 (da)
ES (1) ES2316182T3 (da)
PT (1) PT1045906E (da)
WO (1) WO1999036535A1 (da)

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EP2348043A1 (en) * 2001-10-02 2011-07-27 Genentech, Inc. APO-2 ligand variants and uses thereof
US7741285B2 (en) 2001-11-13 2010-06-22 Genentech, Inc. APO-2 ligand/trail formulations
CA2466054C (en) * 2001-11-13 2012-01-03 Genentech, Inc. Apo-2 ligand/trail formulations
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US8029783B2 (en) 2005-02-02 2011-10-04 Genentech, Inc. DR5 antibodies and articles of manufacture containing same
US20100150931A1 (en) * 2006-11-22 2010-06-17 Centre Hospitalier De L'universite De Montreal Novel receptor for cd40l and uses thereof
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WO2012151317A1 (en) 2011-05-03 2012-11-08 Genentech, Inc. Vascular disruption agents and uses thereof
JP5956580B2 (ja) 2011-09-16 2016-07-27 北京沙▲東▼生物技▲術▼有限公司Ｂｅｉｊｉｎｇ Ｓｕｎｂｉｏ Ｂｉｏｔｅｃｈ Ｃｏ．， Ｌｔｄ． Ｔｒａｉｌ／ａｐｏ２ｌの円順列変異形を含む融合タンパク質、コーディング遺伝子およびそれらの使用
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MX2018006333A (es) 2015-12-01 2018-08-01 Genmab Bv Anticuerpos anti-receptor de muerte 5 (dr5) y metodos de uso de los mismos.
ES2916217T3 (es) 2017-01-05 2022-06-29 Kahr Medical Ltd Una proteína de fusión SIRP1 ALPHA-41BBL y métodos de uso de la misma
DK3565579T3 (da) 2017-01-05 2023-09-04 Kahr Medical Ltd Pd1-41bbl-fusionsprotein og fremgangsmåder til anvendelse deraf
US11299530B2 (en) 2017-01-05 2022-04-12 Kahr Medical Ltd. SIRP alpha-CD70 fusion protein and methods of use thereof
US11566060B2 (en) 2017-01-05 2023-01-31 Kahr Medical Ltd. PD1-CD70 fusion protein and methods of use thereof
IL280102B1 (en) 2018-07-11 2026-07-01 Kahr Medical Ltd Fusion protein containing PD1-4-1BBL and methods of using the same
CA3104780A1 (en) 2018-07-11 2020-01-16 Kahr Medical Ltd. Sirpalpha-4-1bbl variant fusion protein and methods of use thereof

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Also Published As

Publication number Publication date
PT1045906E (pt) 2009-01-27
DE69939732D1 (de) 2008-11-27
CY1108681T1 (el) 2014-04-09
HK1032603A1 (en) 2001-07-27
JP2002508962A (ja) 2002-03-26
ES2316182T3 (es) 2009-04-01
US6740739B1 (en) 2004-05-25
EP2017341A2 (en) 2009-01-21
JP2010246560A (ja) 2010-11-04
EP1045906B1 (en) 2008-10-15
AU2325199A (en) 1999-08-02
EP2017341A3 (en) 2009-04-08
EP1045906A1 (en) 2000-10-25
WO1999036535A9 (en) 2000-03-02
ATE411385T1 (de) 2008-10-15
CA2318029A1 (en) 1999-07-22
WO1999036535A1 (en) 1999-07-22
CA2318029C (en) 2009-05-19

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