DK1126823T3 - Fremgangsmåde til fremstilling af sterilt terapeutisk acceptabelt beclometason-dipropionat - Google Patents

Fremgangsmåde til fremstilling af sterilt terapeutisk acceptabelt beclometason-dipropionat

Info

Publication number
DK1126823T3
DK1126823T3 DK99955895T DK99955895T DK1126823T3 DK 1126823 T3 DK1126823 T3 DK 1126823T3 DK 99955895 T DK99955895 T DK 99955895T DK 99955895 T DK99955895 T DK 99955895T DK 1126823 T3 DK1126823 T3 DK 1126823T3
Authority
DK
Denmark
Prior art keywords
preparation
sterile
therapeutically acceptable
beclometasone dipropionate
directed
Prior art date
Application number
DK99955895T
Other languages
English (en)
Inventor
Eva Bernini
Chiara Malvolti
Raffaella Garzia
Gaetano Brambilla
Paolo Chiesi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of DK1126823T3 publication Critical patent/DK1126823T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DK99955895T 1998-11-03 1999-10-28 Fremgangsmåde til fremstilling af sterilt terapeutisk acceptabelt beclometason-dipropionat DK1126823T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002364A IT1303692B1 (it) 1998-11-03 1998-11-03 Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
PCT/EP1999/008176 WO2000025746A2 (en) 1998-11-03 1999-10-28 A process for the preparation of suspensions of drug particles for inhalation delivery

Publications (1)

Publication Number Publication Date
DK1126823T3 true DK1126823T3 (da) 2007-05-21

Family

ID=11380994

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06017746.6T DK1832279T3 (da) 1998-11-03 1999-10-28 Fremgangsmåde til fremstilling af suspensioner indeholdende partikler med aktivt stof til brug for en indgivelse ved inhalation
DK99955895T DK1126823T3 (da) 1998-11-03 1999-10-28 Fremgangsmåde til fremstilling af sterilt terapeutisk acceptabelt beclometason-dipropionat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06017746.6T DK1832279T3 (da) 1998-11-03 1999-10-28 Fremgangsmåde til fremstilling af suspensioner indeholdende partikler med aktivt stof til brug for en indgivelse ved inhalation

Country Status (26)

Country Link
US (1) US6464958B1 (da)
EP (2) EP1832279B1 (da)
JP (1) JP2002528484A (da)
KR (1) KR100783096B1 (da)
CN (1) CN1158997C (da)
AT (1) ATE352288T1 (da)
AU (1) AU762367B2 (da)
BR (2) BRPI9915251B8 (da)
CA (2) CA2614633C (da)
CY (2) CY1107659T1 (da)
CZ (2) CZ306939B6 (da)
DE (1) DE69935002T2 (da)
DK (2) DK1832279T3 (da)
EA (1) EA003228B1 (da)
ES (1) ES2281197T3 (da)
HU (2) HU230121B1 (da)
IT (1) IT1303692B1 (da)
NO (1) NO20012175L (da)
NZ (1) NZ511305A (da)
PL (1) PL195908B1 (da)
PT (1) PT1126823E (da)
SI (1) SI1126823T1 (da)
SK (2) SK288316B6 (da)
TR (1) TR200101209T2 (da)
WO (1) WO2000025746A2 (da)
ZA (1) ZA200103526B (da)

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ITMI20022674A1 (it) * 2002-12-18 2004-06-19 Chiesi Farma Spa Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.
US20040208833A1 (en) * 2003-02-04 2004-10-21 Elan Pharma International Ltd. Novel fluticasone formulations
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US8912174B2 (en) * 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
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GB0410995D0 (en) * 2004-05-17 2004-06-23 Norton Healthcare Ltd Heat sterilization of glucocorticosteroids
GB0425266D0 (en) * 2004-11-16 2004-12-15 Norton Healthcare Ltd Pharmaceutical manufacturing process
EP2623095A1 (en) * 2004-11-16 2013-08-07 Elan Pharma International Limited Injectable nanoparticulate olanzapine formulations
GB0427568D0 (en) * 2004-12-16 2005-01-19 Resolution Chemicals Ltd Particle-size reduction apparatus, and the use thereof
ES2388287T3 (es) 2005-01-20 2012-10-11 Eratech S.R.L. Procedimiento para la preparación de suspensiones concentradas de fármacos y kit correspondiente
EP1968547A1 (en) * 2005-11-29 2008-09-17 Farmabios S.p.A. Process for the preparation of micronised sterile steroids
JP2009543803A (ja) * 2006-07-12 2009-12-10 エラン・ファルマ・インターナショナル・リミテッド モダフィニルのナノ粒子製剤
WO2009074666A1 (en) * 2007-12-13 2009-06-18 Novartis Ag Organic compounds
KR20120023663A (ko) * 2009-05-25 2012-03-13 키에시 파르마슈티시 엣스. 피. 에이. 폐 계면활성제 및 스테로이드를 포함하는 치료적 조합
CN103501791B (zh) 2011-05-03 2016-05-18 奇斯药制品公司 用于通过吸入给药的改良皮质类固醇悬浮制剂
DK2704687T3 (da) 2011-05-04 2015-10-05 Chiesi Farma Spa Topisk formulering med en corticosteroid som aktiv bestanddel
CN104739811A (zh) * 2015-02-27 2015-07-01 上海臣邦医药科技有限公司 一种糖皮质激素雾化吸入混悬液及其制备方法
TWI773641B (zh) * 2015-05-08 2022-08-11 日商活效製藥股份有限公司 含有糖皮質類固醇（ｇｌｕｃｏｃｏｒｔｉｃｏｉｄｓ）之奈米微粒子之水性懸浮液劑
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Also Published As

Publication number Publication date
NO20012175D0 (no) 2001-05-02
EP1126823A2 (en) 2001-08-29
EP1832279A3 (en) 2008-03-05
PL347908A1 (en) 2002-04-22
BR9915251A (pt) 2001-10-30
NZ511305A (en) 2003-07-25
DK1832279T3 (da) 2015-10-05
KR100783096B1 (ko) 2007-12-07
TR200101209T2 (tr) 2001-09-21
NO20012175L (no) 2001-07-02
CA2349268A1 (en) 2000-05-11
CZ2007211A3 (cs) 2017-09-27
CA2349268C (en) 2009-03-31
SK285487B6 (sk) 2007-02-01
AU1266600A (en) 2000-05-22
ES2281197T3 (es) 2007-09-16
PT1126823E (pt) 2007-04-30
BRPI9917701B1 (pt) 2016-07-19
SK5932001A3 (en) 2001-11-06
AU762367B2 (en) 2003-06-26
CZ306939B6 (cs) 2017-09-27
WO2000025746A2 (en) 2000-05-11
SI1126823T1 (sl) 2007-04-30
HU226734B1 (en) 2009-08-28
US6464958B1 (en) 2002-10-15
JP2002528484A (ja) 2002-09-03
PL195908B1 (pl) 2007-11-30
IT1303692B1 (it) 2001-02-23
CZ300650B6 (cs) 2009-07-08
CN1335766A (zh) 2002-02-13
BRPI9915251B8 (pt) 2021-05-25
ZA200103526B (en) 2002-06-03
CA2614633C (en) 2010-12-21
DE69935002D1 (de) 2007-03-15
SK288316B6 (sk) 2015-11-03
EP1832279A2 (en) 2007-09-12
ATE352288T1 (de) 2007-02-15
HU230121B1 (hu) 2015-08-28
BRPI9915251B1 (pt) 2015-09-01
DE69935002T2 (de) 2007-07-19
CZ20011541A3 (cs) 2001-09-12
CN1158997C (zh) 2004-07-28
EA003228B1 (ru) 2003-02-27
EP1126823B1 (en) 2007-01-24
CY1107659T1 (el) 2013-04-18
EP1832279B1 (en) 2015-07-01
CA2614633A1 (en) 2000-05-11
HU0700446D0 (en) 2007-08-28
EA200100397A1 (ru) 2001-10-22
WO2000025746A3 (en) 2000-10-26
KR20010075656A (ko) 2001-08-09
ITMI982364A1 (it) 2000-05-03
HUP0104230A2 (hu) 2002-03-28
CY1116943T1 (el) 2017-04-05
HUP0104230A3 (en) 2006-07-28

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