DK117687A - Alfa-heterocyclisk substituerede tolunitriler og salte deraf samt deres fremstilling og anvendelse - Google Patents

Alfa-heterocyclisk substituerede tolunitriler og salte deraf samt deres fremstilling og anvendelse

Info

Publication number
DK117687A
DK117687A DK117687A DK117687A DK117687A DK 117687 A DK117687 A DK 117687A DK 117687 A DK117687 A DK 117687A DK 117687 A DK117687 A DK 117687A DK 117687 A DK117687 A DK 117687A
Authority
DK
Denmark
Prior art keywords
alkyl
substd
opt
salts
alkylene
Prior art date
Application number
DK117687A
Other languages
English (en)
Other versions
DK117687D0 (da
DK172190B1 (da
Inventor
Robert Mathews Bowman
Ronald Edward Steele
Leslie Johnston Browne
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25274596&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK117687(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK117687D0 publication Critical patent/DK117687D0/da
Publication of DK117687A publication Critical patent/DK117687A/da
Application granted granted Critical
Publication of DK172190B1 publication Critical patent/DK172190B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
DK117687A 1986-03-07 1987-03-06 Anvendelse af alfa-heterocyclisk substituerede tolunitriler og salte deraf til fremstilling af farmaceutiske præparater, nye forbindelser af denne klasse samt farmaceutisk præparat DK172190B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/837,489 US4749713A (en) 1986-03-07 1986-03-07 Alpha-heterocycle substituted tolunitriles
US83748986 1986-03-07

Publications (3)

Publication Number Publication Date
DK117687D0 DK117687D0 (da) 1987-03-06
DK117687A true DK117687A (da) 1987-09-08
DK172190B1 DK172190B1 (da) 1997-12-22

Family

ID=25274596

Family Applications (1)

Application Number Title Priority Date Filing Date
DK117687A DK172190B1 (da) 1986-03-07 1987-03-06 Anvendelse af alfa-heterocyclisk substituerede tolunitriler og salte deraf til fremstilling af farmaceutiske præparater, nye forbindelser af denne klasse samt farmaceutisk præparat

Country Status (36)

Country Link
US (1) US4749713A (da)
EP (1) EP0236940B3 (da)
JP (1) JPH0755930B2 (da)
KR (1) KR910000482B1 (da)
AT (1) ATE94873T1 (da)
BG (4) BG46598A3 (da)
CA (1) CA1316928C (da)
CY (1) CY1905A (da)
CZ (3) CZ279028B6 (da)
DD (1) DD264432A5 (da)
DE (2) DE3787480T2 (da)
DK (1) DK172190B1 (da)
DZ (1) DZ1055A1 (da)
ES (1) ES2059317T3 (da)
FI (1) FI91857C (da)
HK (1) HK50296A (da)
HU (1) HU202843B (da)
IE (1) IE61101B1 (da)
IL (1) IL81746A (da)
LU (1) LU90128I2 (da)
LV (1) LV5769B4 (da)
MA (1) MA20888A1 (da)
MC (1) MC1805A1 (da)
MT (1) MTP998B (da)
MX (1) MX5496A (da)
MY (1) MY102428A (da)
NL (1) NL970011I2 (da)
NO (2) NO170277C (da)
PH (1) PH24159A (da)
PL (2) PL151490B1 (da)
PT (1) PT84410B (da)
RO (2) RO101533B1 (da)
SK (3) SK279102B6 (da)
SU (3) SU1470184A3 (da)
TN (1) TNSN87033A1 (da)
ZA (1) ZA871637B (da)

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RU2425038C2 (ru) * 2009-11-27 2011-07-27 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Способ получения 1-[ди(4-цианфенил)метил]-1,2,4-триазола
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CN105828822B (zh) 2013-08-14 2019-10-18 诺华股份有限公司 用于治疗癌症的组合疗法
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Also Published As

Publication number Publication date
FI870903L (fi) 1987-09-08
PT84410B (pt) 1989-10-04
NO1998010I1 (no) 1998-03-04
DZ1055A1 (fr) 2004-09-13
KR910000482B1 (ko) 1991-01-25
MY102428A (en) 1992-06-30
TNSN87033A1 (fr) 1990-01-01
BG46598A3 (bg) 1990-01-15
CZ279027B6 (en) 1994-11-16
CY1905A (en) 1987-03-05
HU202843B (en) 1991-04-29
HUT43822A (en) 1987-12-28
SU1549478A3 (ru) 1990-03-07
MA20888A1 (fr) 1987-10-01
DK117687D0 (da) 1987-03-06
FI870903A0 (fi) 1987-03-02
BG45700A3 (bg) 1989-07-14
FI91857C (fi) 1994-08-25
ATE94873T1 (de) 1993-10-15
EP0236940A3 (en) 1989-10-18
PL264460A1 (en) 1988-07-21
DE3787480D1 (de) 1993-10-28
CA1316928C (en) 1993-04-27
EP0236940A2 (en) 1987-09-16
AU6976887A (en) 1987-09-10
MTP998B (en) 1987-08-21
PT84410A (en) 1987-04-01
NL970011I2 (nl) 1997-09-01
BG61204B2 (bg) 1997-02-28
DK172190B1 (da) 1997-12-22
SU1577695A3 (ru) 1990-07-07
NL970011I1 (nl) 1997-05-01
ES2059317T3 (es) 1994-11-16
ZA871637B (en) 1987-10-28
FI91857B (fi) 1994-05-13
IE870575L (en) 1987-09-07
RO101532B1 (en) 1992-11-03
PH24159A (en) 1990-03-22
AU604011B2 (en) 1990-12-06
MC1805A1 (fr) 1987-12-22
CS8707368A2 (en) 1991-02-12
JPH0755930B2 (ja) 1995-06-14
SK736887A3 (en) 1998-06-03
SK736787A3 (en) 1998-06-03
MX5496A (es) 1993-12-01
IE61101B1 (en) 1994-10-05
SK151287A3 (en) 1998-06-03
CS8701512A2 (en) 1991-02-12
NO870937D0 (no) 1987-03-06
SU1470184A3 (ru) 1989-03-30
HK50296A (en) 1996-03-29
IL81746A0 (en) 1987-10-20
SK279103B6 (sk) 1998-06-03
RO101533B1 (en) 1992-06-25
DE3787480T2 (de) 1994-02-24
IL81746A (en) 1992-02-16
KR870008851A (ko) 1987-10-21
EP0236940B1 (en) 1993-09-22
US4749713A (en) 1988-06-07
CZ279028B6 (en) 1994-11-16
JPS62212369A (ja) 1987-09-18
LV5769B4 (lv) 1997-04-20
PL152025B1 (en) 1990-10-31
BG45701A3 (bg) 1989-07-14
NO870937L (no) 1987-09-08
DD264432A5 (de) 1989-02-01
CZ279026B6 (en) 1994-11-16
LV5769A4 (lv) 1996-12-20
NO170277C (no) 1992-09-30
DE19775016I2 (de) 2002-02-21
EP0236940B3 (en) 2011-03-23
NO170277B (no) 1992-06-22
PL151490B1 (en) 1990-09-28
SK279102B6 (sk) 1998-06-03
CS8707367A2 (en) 1991-02-12
LU90128I2 (fr) 1997-10-06
SK279101B6 (sk) 1998-06-03

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