DK545786D0 - Hidtil ukendte insulinderivater og farmaceutiske praeparater, som indeholder disse derivater - Google Patents

Hidtil ukendte insulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Info

Publication number
DK545786D0
DK545786D0 DK545786A DK545786A DK545786D0 DK 545786 D0 DK545786 D0 DK 545786D0 DK 545786 A DK545786 A DK 545786A DK 545786 A DK545786 A DK 545786A DK 545786 D0 DK545786 D0 DK 545786D0
Authority
DK
Denmark
Prior art keywords
derivatives
pharmaceutical preparations
preparations containing
pct
insulin derivatives
Prior art date
Application number
DK545786A
Other languages
English (en)
Other versions
DK159856C (da
DK545786A (da
DK159856B (da
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Priority to DK545786A priority Critical patent/DK159856C/da
Publication of DK545786A publication Critical patent/DK545786A/da
Publication of DK545786D0 publication Critical patent/DK545786D0/da
Publication of DK159856B publication Critical patent/DK159856B/da
Application granted granted Critical
Publication of DK159856C publication Critical patent/DK159856C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK545786A 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater DK159856C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DK119785 1985-03-15
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
PCT/DK1986/000023 WO1986005497A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives
DK8600023 1986-03-14
DK545786 1986-11-14
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Publications (4)

Publication Number Publication Date
DK545786A DK545786A (da) 1986-11-14
DK545786D0 true DK545786D0 (da) 1986-11-14
DK159856B DK159856B (da) 1990-12-17
DK159856C DK159856C (da) 1991-05-06

Family

ID=8102063

Family Applications (3)

Application Number Title Priority Date Filing Date
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
DK545786A DK159856C (da) 1985-03-15 1986-11-14 Humaninsulinderivater og farmaceutiske praeparater, som indeholder disse derivater
DK545686A DK545686D0 (da) 1985-03-15 1986-11-14 Insulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK545686A DK545686D0 (da) 1985-03-15 1986-11-14 Insulinderivater og farmaceutiske praeparater, som indeholder disse derivater

Country Status (11)

Country Link
US (1) US5028586A (da)
EP (2) EP0216832B1 (da)
JP (2) JPS62502538A (da)
AT (2) ATE84546T1 (da)
AU (2) AU596968B2 (da)
DE (2) DE3687500T2 (da)
DK (3) DK119785D0 (da)
FI (2) FI864559L (da)
IL (2) IL78161A0 (da)
NO (2) NO864555D0 (da)
WO (2) WO1986005496A1 (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
FI884914A0 (fi) * 1987-02-25 1988-10-24 Novo Industri As Nya insulinderivat.
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
AU9172991A (en) 1990-12-07 1992-07-08 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (da) * 1991-02-27 1991-02-27 Novo Nordisk As
US5656590A (en) * 1991-05-24 1997-08-12 Amylin Pharmaceuticals, Inc. Treatment of anorexia and related states
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
BR0315818A (pt) * 2002-11-01 2005-09-13 Antares Pharma Inc Método de reduzir os nìveis de glicose sanguìnea médios em um paciente dependente de insulina
EP2033662B1 (en) 2004-01-21 2012-10-17 Novo Nordisk Health Care AG Transglutaminase mediated conjugation of peptides
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
US20090069216A1 (en) * 2006-02-21 2009-03-12 Novo Nordisk A/S Single-Chain Insulin Analogues and Pharmaceutical Formulations Thereof
AU2009210570B2 (en) * 2008-01-30 2014-11-20 Indiana University Research And Technology Corporation Ester-based insulin prodrugs
CN102300580A (zh) * 2008-12-19 2011-12-28 印第安纳大学研究及科技有限公司 二肽连接的药剂
CN102325539A (zh) 2008-12-19 2012-01-18 印第安纳大学研究及科技有限公司 基于酰胺的胰高血糖素超家族肽前药
JP5912112B2 (ja) 2010-06-24 2016-04-27 インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションＩｎｄｉａｎａ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ａｎｄ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐｏｒａｔｉｏｎ アミド系インスリンプロドラッグ
US9573987B2 (en) 2011-12-20 2017-02-21 Indiana University Research And Technology Corporation CTP-based insulin analogs for treatment of diabetes
AU2013323669B2 (en) 2012-09-26 2018-03-01 Indiana University Research And Technology Corporation Insulin analog dimers
WO2014158900A1 (en) 2013-03-14 2014-10-02 Indiana University Research And Technology Corporation Insulin-incretin conjugates
WO2016049174A1 (en) 2014-09-24 2016-03-31 Indiana University Research And Technology Corporation Lipidated amide-based insulin prodrugs
ES2822994T3 (es) 2014-09-24 2021-05-05 Univ Indiana Res & Tech Corp Conjugados de incretina-insulina

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK146482C (da) * 1979-04-13 1986-10-06 Shionogi & Co Fremgangsmaade til fremstilling af et b30-threonin-insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
DE3687500T2 (de) 1993-07-01
IL78160A (en) 1991-06-10
NO864555L (no) 1986-11-14
ATE56022T1 (de) 1990-09-15
DK119785D0 (da) 1985-03-15
JPS62502538A (ja) 1987-10-01
NO174278C (no) 1994-04-13
FI864559A0 (fi) 1986-11-10
FI864559A7 (fi) 1986-11-10
NO864555D0 (no) 1986-11-14
JPS62502196A (ja) 1987-08-27
AU5622786A (en) 1986-10-13
DK159856C (da) 1991-05-06
FI864559L (fi) 1986-11-10
FI864560L (fi) 1986-11-10
NO864556L (no) 1986-11-14
AU596968B2 (en) 1990-05-24
DK545786A (da) 1986-11-14
ATE84546T1 (de) 1993-01-15
EP0216833A1 (en) 1987-04-08
EP0216832B1 (en) 1990-08-29
AU5622686A (en) 1986-10-13
EP0216832A1 (en) 1987-04-08
IL78161A0 (en) 1986-07-31
DE3687500D1 (de) 1993-02-25
US5028586A (en) 1991-07-02
DK159856B (da) 1990-12-17
DK545686A (da) 1986-11-14
DE3673737D1 (de) 1990-10-04
DK545686D0 (da) 1986-11-14
IL78160A0 (en) 1986-07-31
WO1986005497A1 (en) 1986-09-25
FI864560A0 (fi) 1986-11-10
EP0216833B1 (en) 1993-01-13
NO864556D0 (no) 1986-11-14
NO174278B (no) 1994-01-03
WO1986005496A1 (en) 1986-09-25
FI93460B (fi) 1994-12-30
FI93460C (fi) 1995-04-10

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PBP Patent lapsed