DK1200606T3 - Streptomyces avermitilis genet, der styrer ratioen af B2:B1 avermectiner - Google Patents

Streptomyces avermitilis genet, der styrer ratioen af B2:B1 avermectiner

Info

Publication number: DK1200606T3
Authority: DK; Denmark
Prior art keywords: avermectins; controls; ratio; streptomyces avermitilis; avermitilis gene
Prior art date: 1999-08-12

Application number

DK00944154T

Other languages

Danish (da)

English (en)

Inventor

Yan Chen

Claes Gustafsson

Sun Ai Raillard

Anke Krebber

Jeremy Stephen Minshull

Kim Jonelle Stutzman-Engwall

Original Assignee

Pfizer Prod Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-12

Filing date

2000-07-24

Publication date

2007-01-08

2000-07-24 Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc

2007-01-08 Application granted granted Critical

2007-01-08 Publication of DK1200606T3 publication Critical patent/DK1200606T3/da

Links

239000005660 Abamectin Substances 0.000 title 1
241001468227 Streptomyces avermitilis Species 0.000 title 1
108090000623 proteins and genes Proteins 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK00944154T 1999-08-12 2000-07-24 Streptomyces avermitilis genet, der styrer ratioen af B2:B1 avermectiner DK1200606T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US14864599P	1999-08-12	1999-08-12

Publications (1)

Publication Number	Publication Date
DK1200606T3 true DK1200606T3 (da)	2007-01-08

Family

ID=22526696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00944154T DK1200606T3 (da)	1999-08-12	2000-07-24	Streptomyces avermitilis genet, der styrer ratioen af B2:B1 avermectiner

Country Status (39)

Country	Link
US (3)	US6632673B1 (de)
EP (1)	EP1200606B1 (de)
JP (1)	JP3884651B2 (de)
KR (1)	KR100489856B1 (de)
CN (1)	CN1186446C (de)
AP (1)	AP2002002418A0 (de)
AR (1)	AR022646A1 (de)
AT (1)	ATE341632T1 (de)
AU (1)	AU778837B2 (de)
BG (1)	BG65902B1 (de)
BR (1)	BRPI0013119B8 (de)
CA (1)	CA2380872C (de)
CO (1)	CO5290295A1 (de)
CY (1)	CY1105778T1 (de)
CZ (1)	CZ304402B6 (de)
DE (1)	DE60031126T2 (de)
DK (1)	DK1200606T3 (de)
EA (1)	EA200200056A1 (de)
ES (1)	ES2272299T3 (de)
GT (1)	GT200000136A (de)
HK (1)	HK1046710B (de)
HR (1)	HRP20020130A2 (de)
HU (1)	HU230600B1 (de)
IL (2)	IL147563A0 (de)
IS (1)	IS6250A (de)
MA (1)	MA26813A1 (de)
MX (1)	MXPA02001513A (de)
NO (1)	NO20020664D0 (de)
NZ (1)	NZ516517A (de)
OA (1)	OA11998A (de)
PA (1)	PA8499501A1 (de)
PE (1)	PE20010690A1 (de)
PL (1)	PL203818B1 (de)
PT (1)	PT1200606E (de)
SK (1)	SK288086B6 (de)
TN (1)	TNSN00171A1 (de)
UY (1)	UY26286A1 (de)
WO (1)	WO2001012821A1 (de)
ZA (1)	ZA200201072B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2001012821A1 (en) *	1999-08-12	2001-02-22	Pfizer Products Inc.	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins
RS50813B (sr) *	2002-02-12	2010-08-31	Pfizer Products Inc.	Streptomyces avermitilis gen koji određuje odnos b2:b1 avermektina
US7943160B2 (en) *	2002-05-09	2011-05-17	Scimetrics Limited Corp.	Pest control methods
US9493744B2 (en) *	2012-06-20	2016-11-15	Genentech, Inc.	Methods for viral inactivation and other adventitious agents
KR102657859B1 (ko)	2021-04-07	2024-04-16	윤재식	일체형 내화 소켓

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN167980B (de) *	1987-01-23	1991-01-19	Pfizer
US5525506A (en)	1987-01-23	1996-06-11	Pfizer Inc.	Process for production of avermectins and cultures therefor
US5238848A (en)	1987-01-23	1993-08-24	Pfizer Inc	Cultures for production of avermectins
US5234831A (en)	1987-01-23	1993-08-10	Pfizer Inc	Cultures for production of B avermectins
ATE89604T1 (de)	1987-10-23	1993-06-15	Pfizer	Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen.
US5240850A (en)	1987-10-23	1993-08-31	Pfizer Inc.	Cultures for production of avermectin aglycones
US5252474A (en)	1989-03-31	1993-10-12	Merck & Co., Inc.	Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
DE69023036T2 (de)	1989-03-31	1996-06-13	Merck & Co Inc	Klonierung von Streptomyces avermitilis Genen zur Biosynthese von Avermectin und Verfahren zu ihrer Verwendung.
KR100221385B1 (ko)	1993-07-30	1999-10-01	디. 제이. 우드	스트렙토마이세스 아베르미틸리스로 부터의 측쇄 알파-케토산 데하이드로게나제 복합체를 암호화하는 유전자
FI942725A7 (fi)	1993-12-16	1995-06-17	Pfizer	Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
US5837458A (en)	1994-02-17	1998-11-17	Maxygen, Inc.	Methods and compositions for cellular and metabolic engineering
US6335160B1 (en)	1995-02-17	2002-01-01	Maxygen, Inc.	Methods and compositions for polypeptide engineering
US6117679A (en)	1994-02-17	2000-09-12	Maxygen, Inc.	Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en)	1994-02-17	1997-02-25	Affymax Technologies N.V.	Methods for in vitro recombination
US6096548A (en)	1996-03-25	2000-08-01	Maxygen, Inc.	Method for directing evolution of a virus
CA2266423A1 (en)	1996-09-27	1998-04-02	Maxygen, Inc.	Methods for optimization of gene therapy by recursive sequence shuffling and selection
EP1717322B1 (de)	1997-01-17	2012-07-18	Codexis Mayflower Holdings, LLC	Evolution ganzer Zellen durch rekursive Sequenzrekombination
AU1449499A (en)	1997-10-31	1999-05-24	Maxygen, Incorporated	Modification of virus tropism and host range by viral genome shuffling
PL194270B1 (pl) *	1998-02-13	2007-05-31	Pfizer Prod Inc	Wyizolowana cząsteczka polinukleotydowa, cząsteczka oligonukleotydowa, zrekombinowany wektor, komórka gospodarza, wyizolowany produkt genu AveC S. avermitilis, wyizolowany produkt homologu genu AveC S. hygroscopicus, sposób wytwarzania zrekombinowanego produktu genu AveC, sposób wytwarzania zrekombinowanego produktu homologu genu AveC, cząsteczka polinukleotydowa, wektor do zastępowania genu, sposób identyfikowania mutacji otwartej ramki odczytuAveC, sposób wytwarzania nowych szczepów S. avermitilis, szczep S. avermitilis i sposób wytwarzaniaawermektyn
US6248579B1 (en) *	1998-02-13	2001-06-19	Pfizer Inc	Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins
WO2001012821A1 (en) *	1999-08-12	2001-02-22	Pfizer Products Inc.	Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins

2000
- 2000-07-24 WO PCT/IB2000/001017 patent/WO2001012821A1/en not_active Ceased
- 2000-07-24 KR KR10-2002-7001807A patent/KR100489856B1/ko not_active Expired - Lifetime
- 2000-07-24 HU HU0202487A patent/HU230600B1/hu unknown
- 2000-07-24 ES ES00944154T patent/ES2272299T3/es not_active Expired - Lifetime
- 2000-07-24 PL PL353874A patent/PL203818B1/pl unknown
- 2000-07-24 HK HK02108367.6A patent/HK1046710B/zh unknown
- 2000-07-24 DE DE60031126T patent/DE60031126T2/de not_active Expired - Lifetime
- 2000-07-24 CZ CZ2002-296A patent/CZ304402B6/cs not_active IP Right Cessation
- 2000-07-24 OA OA1200200025A patent/OA11998A/en unknown
- 2000-07-24 AU AU58386/00A patent/AU778837B2/en not_active Expired
- 2000-07-24 BR BRPI0013119A patent/BRPI0013119B8/pt not_active IP Right Cessation
- 2000-07-24 EA EA200200056A patent/EA200200056A1/ru unknown
- 2000-07-24 AP APAP/P/2002/002418A patent/AP2002002418A0/en unknown
- 2000-07-24 AT AT00944154T patent/ATE341632T1/de active
- 2000-07-24 EP EP00944154A patent/EP1200606B1/de not_active Expired - Lifetime
- 2000-07-24 SK SK139-2002A patent/SK288086B6/sk not_active IP Right Cessation
- 2000-07-24 DK DK00944154T patent/DK1200606T3/da active
- 2000-07-24 PT PT00944154T patent/PT1200606E/pt unknown
- 2000-07-24 NZ NZ516517A patent/NZ516517A/en unknown
- 2000-07-24 JP JP2001516908A patent/JP3884651B2/ja not_active Expired - Lifetime
- 2000-07-24 CN CNB008117470A patent/CN1186446C/zh not_active Expired - Lifetime
- 2000-07-24 MX MXPA02001513A patent/MXPA02001513A/es active IP Right Grant
- 2000-07-24 CA CA002380872A patent/CA2380872C/en not_active Expired - Lifetime
- 2000-07-24 IL IL14756300A patent/IL147563A0/xx unknown
- 2000-07-24 HR HR20020130A patent/HRP20020130A2/hr not_active Application Discontinuation
- 2000-08-04 CO CO00058605A patent/CO5290295A1/es not_active Application Discontinuation
- 2000-08-10 US US09/637,040 patent/US6632673B1/en not_active Expired - Lifetime
- 2000-08-10 GT GT200000136A patent/GT200000136A/es unknown
- 2000-08-10 PE PE2000000812A patent/PE20010690A1/es not_active Application Discontinuation
- 2000-08-10 UY UY26286A patent/UY26286A1/es not_active Application Discontinuation
- 2000-08-10 PA PA20008499501A patent/PA8499501A1/es unknown
- 2000-08-10 AR ARP000104131A patent/AR022646A1/es active IP Right Grant
- 2000-08-11 TN TNTNSN00171A patent/TNSN00171A1/fr unknown
2002
- 2002-01-10 IL IL147563A patent/IL147563A/en active IP Right Grant
- 2002-01-25 IS IS6250A patent/IS6250A/is unknown
- 2002-02-07 ZA ZA200201072A patent/ZA200201072B/en unknown
- 2002-02-07 MA MA26513A patent/MA26813A1/fr unknown
- 2002-02-11 NO NO20020664A patent/NO20020664D0/no not_active Application Discontinuation
- 2002-03-05 BG BG106479A patent/BG65902B1/bg unknown
2003
- 2003-06-11 US US10/412,444 patent/US20040009560A1/en not_active Abandoned
- 2003-06-11 US US10/412,450 patent/US7858340B2/en not_active Expired - Fee Related
2006
- 2006-11-13 CY CY20061101647T patent/CY1105778T1/el unknown

Also Published As

Publication number	Publication date
US20030232415A1 (en)	2003-12-18
SK288086B6 (sk)	2013-06-03
PL203818B1 (pl)	2009-11-30
KR20020029379A (ko)	2002-04-18
ATE341632T1 (de)	2006-10-15
CN1186446C (zh)	2005-01-26
ES2272299T3 (es)	2007-05-01
MA26813A1 (fr)	2004-12-20
CA2380872C (en)	2007-11-27
OA11998A (en)	2006-04-18
CA2380872A1 (en)	2001-02-22
BG65902B1 (bg)	2010-04-30
EP1200606B1 (de)	2006-10-04
CY1105778T1 (el)	2011-02-02
US6632673B1 (en)	2003-10-14
CZ2002296A3 (cs)	2002-08-14
JP3884651B2 (ja)	2007-02-21
KR100489856B1 (ko)	2005-05-17
BRPI0013119B8 (pt)	2021-05-25
IL147563A (en)	2009-06-15
IS6250A (is)	2002-01-25
HRP20020130A2 (en)	2003-06-30
UY26286A1 (es)	2001-03-16
EA200200056A1 (ru)	2002-06-27
WO2001012821A1 (en)	2001-02-22
HU230600B1 (hu)	2017-02-28
HUP0202487A3 (en)	2004-07-28
PT1200606E (pt)	2006-12-29
HUP0202487A2 (en)	2002-10-28
BR0013119B1 (pt)	2014-02-25
PA8499501A1 (es)	2001-12-14
EP1200606A1 (de)	2002-05-02
HK1046710A1 (en)	2003-01-24
PL353874A1 (en)	2003-12-01
CO5290295A1 (es)	2003-06-27
NZ516517A (en)	2003-10-31
SK1392002A3 (en)	2002-12-03
ZA200201072B (en)	2003-04-30
HK1046710B (zh)	2005-05-13
MXPA02001513A (es)	2002-07-02
NO20020664L (no)	2002-02-11
PE20010690A1 (es)	2001-07-06
DE60031126T2 (de)	2007-02-08
AP2002002418A0 (en)	2002-03-31
AU778837B2 (en)	2004-12-23
BR0013119A (pt)	2002-04-23
US7858340B2 (en)	2010-12-28
BG106479A (bg)	2002-10-31
CZ304402B6 (cs)	2014-04-16
DE60031126D1 (de)	2006-11-16
JP2003507017A (ja)	2003-02-25
IL147563A0 (en)	2002-08-14
GT200000136A (es)	2002-02-01
NO20020664D0 (no)	2002-02-11
AU5838600A (en)	2001-03-13
TNSN00171A1 (fr)	2005-11-10
US20040009560A1 (en)	2004-01-15
AR022646A1 (es)	2002-09-04
CN1373809A (zh)	2002-10-09

Publication	Publication Date	Title
AU5515901A (en)	2001-07-09	Gamma-phosphoester nucleoside triphosphates
MXPA03001775A (es)	2003-06-04	Derivados de nucleosidos.
AU2002363246A1 (en)	2003-05-12	Game with multiple chambers
AU2001278694A1 (en)	2002-02-18	Avermectin derivatives
AU2002352357A1 (en)	2003-06-17	Trioxane derivatives
NO20020665D0 (no)	2002-02-11	Streptomyces Avermitilis gen som bestemmer forholdet til B2:B1 avermectiner
WO2003075852A3 (en)	2004-07-15	Antibiotic composition
NO20004044D0 (no)	2000-08-11	Streptomyces Avertimilis gen som styrer forholdet av B2:B1 avermectiner
NO20020664D0 (no)	2002-02-11	Streptomyces Avermitilis gen som bestemmer forholdet B2:B1 avermectiner
ZA200405345B (en)	2005-06-14	Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins.
AU2930601A (en)	2001-07-24	Methods of increasing the glucose responsiveness of pancreatic beta-cells
DK1200605T3 (da)	2005-03-21	Streptomyces avermitilis gen, der dirigerer forholdet imellem B2:B1 avermectiner
DK1585753T3 (da)	2006-10-02	Hidtil ukendte, semisyntetiske makrolidantibiotika af azalidserien
AU2690500A (en)	2000-09-14	Avermectin aglycon synthase genes
PL1638984T3 (pl)	2008-02-29	Monosacharydowe pochodne awermektyny B1
MXPA03008589A (es)	2003-12-08	Derivados de azucar citotoxicos selectivos de topoisomerasa i de indolopirrolocarbazoles.
AU2001277712A1 (en)	2002-02-18	Avermectin derivatives
AU2002230657A1 (en)	2002-06-11	Haplotypes of the sah gene
AU5916700A (en)	2001-01-30	Combination chemotherapy
HK1071531A (en)	2005-07-22	Game with multiple chambers
AU2002233703A1 (en)	2002-09-04	Compositions with controlled drug release
ES1049021Y (es)	2002-02-16	Ambientador de sobremesa multiforma.
AU2002346601A1 (en)	2003-06-17	Novel 11-o-substituted ketolide derivatives
AU2002342652A1 (en)	2003-03-24	Pyridine derivatives as raf kinase inhibitors