DK1307457T3 - Azabicycliske forbindelser, deres fremstilling og deres anvendelse som medikamenter, især som antibakterielle midler - Google Patents
Azabicycliske forbindelser, deres fremstilling og deres anvendelse som medikamenter, især som antibakterielle midlerInfo
- Publication number
- DK1307457T3 DK1307457T3 DK01958173T DK01958173T DK1307457T3 DK 1307457 T3 DK1307457 T3 DK 1307457T3 DK 01958173 T DK01958173 T DK 01958173T DK 01958173 T DK01958173 T DK 01958173T DK 1307457 T3 DK1307457 T3 DK 1307457T3
- Authority
- DK
- Denmark
- Prior art keywords
- drugs
- preparation
- antibacterial agents
- azabicyclic compounds
- azabicyclic
- Prior art date
Links
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0010121A FR2812635B1 (fr) | 2000-08-01 | 2000-08-01 | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| PCT/FR2001/002418 WO2002010172A1 (fr) | 2000-08-01 | 2001-07-24 | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1307457T3 true DK1307457T3 (da) | 2004-08-09 |
Family
ID=8853181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01958173T DK1307457T3 (da) | 2000-08-01 | 2001-07-24 | Azabicycliske forbindelser, deres fremstilling og deres anvendelse som medikamenter, især som antibakterielle midler |
Country Status (41)
| Country | Link |
|---|---|
| US (5) | US7112592B2 (de) |
| EP (1) | EP1307457B1 (de) |
| JP (2) | JP4515704B2 (de) |
| KR (1) | KR100632906B1 (de) |
| CN (1) | CN1289500C (de) |
| AP (1) | AP1614A (de) |
| AR (1) | AR031716A1 (de) |
| AT (1) | ATE263768T1 (de) |
| AU (2) | AU7990501A (de) |
| BG (1) | BG66094B1 (de) |
| BR (1) | BRPI0112986B8 (de) |
| CA (1) | CA2417475C (de) |
| CR (1) | CR6895A (de) |
| CZ (1) | CZ294956B6 (de) |
| DE (1) | DE60102702T2 (de) |
| DK (1) | DK1307457T3 (de) |
| DZ (1) | DZ3397A1 (de) |
| EA (1) | EA004920B1 (de) |
| EC (1) | ECSP034460A (de) |
| EE (1) | EE05183B1 (de) |
| ES (1) | ES2220793T3 (de) |
| FR (1) | FR2812635B1 (de) |
| HR (1) | HRP20030034B1 (de) |
| HU (1) | HU226889B1 (de) |
| IL (2) | IL154187A0 (de) |
| MA (1) | MA26938A1 (de) |
| ME (2) | MEP17108A (de) |
| MX (1) | MXPA03000881A (de) |
| NO (1) | NO324940B1 (de) |
| NZ (1) | NZ523707A (de) |
| OA (1) | OA12347A (de) |
| PL (2) | PL216028B1 (de) |
| PT (1) | PT1307457E (de) |
| RS (1) | RS50214B (de) |
| SI (1) | SI1307457T1 (de) |
| SK (1) | SK287597B6 (de) |
| TR (1) | TR200400859T4 (de) |
| TW (1) | TWI292401B (de) |
| UA (1) | UA73791C2 (de) |
| WO (1) | WO2002010172A1 (de) |
| ZA (1) | ZA200300676B (de) |
Families Citing this family (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2844273B1 (fr) * | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| FR2848210B1 (fr) * | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
| US7439253B2 (en) * | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| ATE529111T1 (de) | 2005-12-07 | 2011-11-15 | Basilea Pharmaceutica Ag | Nützliche monobactam-antibiotika |
| CA2657618C (en) | 2006-07-13 | 2016-10-11 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication |
| WO2008008398A2 (en) * | 2006-07-14 | 2008-01-17 | Shionogi & Co., Ltd. | Oxime compounds and the use thereof |
| WO2008039420A2 (en) * | 2006-09-27 | 2008-04-03 | Merck & Co., Inc. | Novel inhibitors of beta-lactamase |
| CN101589047A (zh) * | 2006-10-23 | 2009-11-25 | Irm责任有限公司 | 组织蛋白酶类抑制剂 |
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| ES2422603T3 (es) * | 2007-05-31 | 2013-09-12 | Shionogi & Co | Compuestos oxiimino y el uso de estos |
| FR2921060B1 (fr) * | 2007-09-14 | 2012-06-15 | Novexel | Nouveau procede de preparation d'une piperidine disubsituee et nouveaux intermediaires |
| MY162532A (en) * | 2008-01-18 | 2017-06-15 | Merck Sharp & Dohme | Beta-lactamase inhibitors |
| WO2009151152A1 (en) | 2008-06-11 | 2009-12-17 | Shionogi & Co., Ltd. | Oxycarbamoyl compounds and the use thereof |
| EP3260551A1 (de) | 2008-06-19 | 2017-12-27 | Astra Zeneca Holding France | Verwendung von (1r,2s,5r)-1,6-diazabicyclo [3.2.1]oktan-2-carboxamid, 7-oxo-6-(sulfooxy)-, mononatriumsalz als diagnostisches reagens zum nachweis von serin-beta-lactamasen |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2937034B1 (fr) | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
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| CN103328476B (zh) * | 2010-12-22 | 2016-12-28 | 明治制果药业株式会社 | 光学活性二氮杂环辛烷衍生物及其制备方法 |
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| KR102790878B1 (ko) | 2018-08-09 | 2025-04-02 | 앤타바이오 에스에이에스 | 세린 베타-락타마제의 억제제로서 다이아자바이사이클로옥타논 |
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| EP4146651B1 (de) | 2021-05-07 | 2026-03-04 | Ningxia Academy of Agriculture and Forestry Sciences | Sulfonylamidinsubstituierte verbindungen und ihre verwendung als beta-lactamase-hemmer |
| US11814385B2 (en) | 2021-06-25 | 2023-11-14 | University Of South Florida | Small molecule inhibitors targeting Clostridioides difficile sporulation |
| KR20240041506A (ko) | 2022-09-23 | 2024-04-01 | 주식회사 경보제약 | 아비박탐 나트륨 염의 안정한 일수화물 형태 및 그의 제조 방법 |
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| JPS4939678B1 (de) * | 1968-05-06 | 1974-10-28 | ||
| US4024147A (en) * | 1972-06-30 | 1977-05-17 | John Wyeth & Brother Limited | Heterocyclic compounds |
| US4049821A (en) * | 1976-05-12 | 1977-09-20 | A. H. Robins Company, Inc. | Method of treating allergy |
| EP0260057A3 (de) * | 1986-09-02 | 1989-02-01 | The University Of Melbourne | 2-Oxo-4-Karboxypyrimidine |
| JPS63119471A (ja) * | 1986-09-02 | 1988-05-24 | ザ・ユニバーシテイ・オブ・メルボルン | 2−オキソ−4−カルボキシ−ピリミジン |
| NZ274915A (en) * | 1993-12-29 | 1997-11-24 | Pfizer | N-(hetero)aryl methyl diazabicycloalkane derivatives |
| TW358097B (en) * | 1996-05-24 | 1999-05-11 | Hoffmann La Roche | Beta-lactams and their process and pharmaceutical compositions |
| HUP0001741A3 (en) * | 1996-08-02 | 2000-11-28 | Smithkline Beecham Plc | Azabicyclic carbamoyloxy mutilin derivatives for antibacterial use, process for preparing them, pharmaceuticals contg. them and their use |
| WO1998034919A1 (en) * | 1997-02-10 | 1998-08-13 | Pfizer Products Inc. | 2-amino-6-(2-substituted-4-phenoxy)-substituted-pyridines |
| US6060585A (en) * | 1997-03-04 | 2000-05-09 | Wisconsin Alumni Research Foundation | β-polypeptide foldamers of well-defined secondary structure |
| KR100207096B1 (ko) * | 1997-07-08 | 1999-07-15 | 이명환 | 시사프라이드의 제조 방법 |
| WO1999054284A1 (en) * | 1998-04-20 | 1999-10-28 | Fujisawa Pharmaceutical Co., Ltd. | Anthranilic acid derivatives as inhibitors of the cgmp-phosphodiesterase |
| GB9817029D0 (en) * | 1998-08-05 | 1998-09-30 | Smithkline Beecham Plc | Novel compounds |
| FR2784682B1 (fr) * | 1998-10-15 | 2002-12-06 | Hoechst Marion Roussel Inc | Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments |
| ATE272633T1 (de) * | 1998-12-23 | 2004-08-15 | Lilly Co Eli | Aromatische amiden |
| KR20010101355A (ko) * | 1999-01-02 | 2001-11-14 | 로버트 흐라이탁, 미쉘 베스트 | 신규한 말론산 유도체, 이의 제조 방법, 이의 용도 및이를 함유하는 약제학적 조성물(인자 xa 활성 억제) |
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
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