DK1329461T3 - Fremgangsmåde til fjernelse af humane serum-albumin-polymerer - Google Patents

Fremgangsmåde til fjernelse af humane serum-albumin-polymerer

Info

Publication number
DK1329461T3
DK1329461T3 DK01978882.7T DK01978882T DK1329461T3 DK 1329461 T3 DK1329461 T3 DK 1329461T3 DK 01978882 T DK01978882 T DK 01978882T DK 1329461 T3 DK1329461 T3 DK 1329461T3
Authority
DK
Denmark
Prior art keywords
serum albumin
human serum
removal
albumin polymers
multimers
Prior art date
Application number
DK01978882.7T
Other languages
English (en)
Inventor
Satoshi Adachi
Hiroshi Mizokami
Yoshitaka Tajima
Yoshinobu Miyatsu
Toshinobu Nouchi
Yoshitaka Ushio
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Application granted granted Critical
Publication of DK1329461T3 publication Critical patent/DK1329461T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK01978882.7T 2000-10-24 2001-10-24 Fremgangsmåde til fjernelse af humane serum-albumin-polymerer DK1329461T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000324029A JP4798832B2 (ja) 2000-10-24 2000-10-24 ヒト血清アルブミン多量体の除去方法
PCT/JP2001/009335 WO2002034786A1 (en) 2000-10-24 2001-10-24 Method of eliminating human serum albumin polymers

Publications (1)

Publication Number Publication Date
DK1329461T3 true DK1329461T3 (da) 2012-01-30

Family

ID=18801620

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01978882.7T DK1329461T3 (da) 2000-10-24 2001-10-24 Fremgangsmåde til fjernelse af humane serum-albumin-polymerer

Country Status (11)

Country Link
US (1) US7001885B2 (da)
EP (1) EP1329461B8 (da)
JP (1) JP4798832B2 (da)
KR (1) KR100847883B1 (da)
CN (1) CN1406245B (da)
AT (1) ATE535544T1 (da)
AU (1) AU783871B2 (da)
CA (1) CA2395589C (da)
DK (1) DK1329461T3 (da)
ES (1) ES2373035T3 (da)
WO (1) WO2002034786A1 (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
DE60121196T2 (de) * 2000-10-24 2007-07-12 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Verfahren zur monomerisierung von humanen serumalbumin-polymeren
SE526227C2 (sv) * 2002-05-15 2005-08-02 North China Pharmaceutical Group Metod för rening av rekombinant humant serumalbumin
JPWO2005004902A1 (ja) * 2003-07-10 2006-08-24 ニプロ株式会社 プラスチック容器入り組換えヒト血清アルブミン製剤
FR2866890B1 (fr) 2004-02-27 2008-04-04 Lab Francais Du Fractionnement Procede de purification d'albumine comprenant une etape de nanofiltration, solution et composition a usage therapeutique la contenant
CN102190722B (zh) * 2010-03-16 2014-03-26 上海欣瑞特生物医药技术有限公司 一种纯化重组人血白蛋白的方法
KR101595151B1 (ko) * 2012-01-31 2016-02-18 이화여자대학교 산학협력단 일산화질소에 의해 형성되는 알부민 다량체 및 알부민 구조변형체
US20140186447A1 (en) * 2012-12-28 2014-07-03 Abraxis Bioscience, Llc Nanoparticle compositions of albumin and paclitaxel
US10705070B1 (en) 2015-03-05 2020-07-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug
US10527604B1 (en) 2015-03-05 2020-01-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
KR102662031B1 (ko) 2016-10-04 2024-05-03 알부메딕스 리미티드 재조합 효모-유래 혈청 알부민의 용도
CN107216383A (zh) * 2017-07-13 2017-09-29 同路生物制药有限公司 一种人血白蛋白的制备方法及该人血白蛋白
JP7832108B2 (ja) 2019-10-28 2026-03-17 アブラクシス バイオサイエンス， エルエルシー アルブミンおよびラパマイシンの医薬組成物
EP4069200A1 (en) 2019-12-04 2022-10-12 Albumedix Ltd Methods and compositions produced thereby
US12161777B2 (en) 2020-07-02 2024-12-10 Davol Inc. Flowable hemostatic suspension
US11739166B2 (en) 2020-07-02 2023-08-29 Davol Inc. Reactive polysaccharide-based hemostatic agent
EP4267210A1 (en) 2020-12-28 2023-11-01 Davol Inc. Reactive dry powdered hemostatic materials comprising a protein and a multifunctionalized modified polyethylene glycol based crosslinking agent

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169829A (en) * 1972-07-05 1979-10-02 Institut Merieux Process for the preparation of purified albumin and albumin obtained by said process
IL66614A (en) 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
US4705848A (en) * 1986-06-02 1987-11-10 International Minerals & Chemical Corp. Isolation of bioactive, monomeric growth hormone
IL88326A (en) 1987-11-18 1993-03-15 Gist Brocades Nv Purification of serum albumin
JP2926722B2 (ja) 1988-10-20 1999-07-28 吉富製薬株式会社 アルブミン製剤及びその製造方法
JP3554796B2 (ja) * 1988-10-31 2004-08-18 三菱ウェルファーマ株式会社 アルブミン製剤及びその製造方法
JPH0768137B2 (ja) * 1989-06-15 1995-07-26 株式会社ミドリ十字 アルブミン製剤及びその製法
JPH0671434B2 (ja) * 1989-09-18 1994-09-14 株式会社ミドリ十字 ヒト血清アルブミンの製造方法
JPH04234326A (ja) * 1990-12-27 1992-08-24 Green Cross Corp:The アルブミン製剤及びその製法
JPH0671434A (ja) 1991-05-30 1994-03-15 Tadahiro Omi クリーンチャンバーの溶接方法
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
JP3508149B2 (ja) * 1993-02-25 2004-03-22 三菱ウェルファーマ株式会社 ヒト血清アルブミンおよびその製造方法
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
JPH07126182A (ja) 1993-10-27 1995-05-16 Green Cross Corp:The 組換えヒト血清アルブミン製剤の滅菌方法
CA2138349A1 (en) * 1993-12-17 1995-06-18 Welfide Corporation Method for decoloring human serum albumin
JP3702474B2 (ja) * 1994-06-01 2005-10-05 三菱ウェルファーマ株式会社 血清アルブミン製剤の製造方法
JP3840674B2 (ja) 1994-08-31 2006-11-01 三菱ウェルファーマ株式会社 遺伝子操作に由来するヒト血清アルブミンの精製方法
EP1500661A1 (en) * 1998-06-01 2005-01-26 Genetech, Inc. Separation of protein monomers from aggregates by use of ion-exchange chromatography

Also Published As

Publication number Publication date
KR20020065608A (ko) 2002-08-13
ES2373035T3 (es) 2012-01-30
US20020183492A1 (en) 2002-12-05
EP1329461B8 (en) 2012-03-14
EP1329461A1 (en) 2003-07-23
US7001885B2 (en) 2006-02-21
WO2002034786A1 (en) 2002-05-02
EP1329461A4 (en) 2004-12-01
AU783871B2 (en) 2005-12-15
JP2002128795A (ja) 2002-05-09
JP4798832B2 (ja) 2011-10-19
ATE535544T1 (de) 2011-12-15
CA2395589A1 (en) 2002-05-02
KR100847883B1 (ko) 2008-07-23
CN1406245A (zh) 2003-03-26
CN1406245B (zh) 2010-05-26
EP1329461B1 (en) 2011-11-30
CA2395589C (en) 2012-08-28
AU1093502A (en) 2002-05-06

Similar Documents

Publication Publication Date Title
DK1329461T3 (da) Fremgangsmåde til fjernelse af humane serum-albumin-polymerer
DK83093D0 (da) Fremgangsmaade
PE84799A1 (es) Metodos mejorados para el procesamiento de proteina c activada
DE69711034D1 (de) Wässrige fluorpolymerlösungen zur behandlung von harten oberflächen
DE69628564D1 (de) Verfahren zur reinigung von viren mit chromatographie
DE69806498D1 (de) Behandlung von kontaktlinsen mit wässrigen, alkalicarbonat-haltigen lösungen
DE60137836D1 (de) Vorrichtung zur Bearbeitung von Brillengläsern
DE60011540D1 (de) Verfahren zur Desinfektion von Kontaktlinsen
DE69030765D1 (de) Medien zur zellzucht und verfahren dazu
MXPA03000612A (es) Metodos y procesos mejorados para desinfeccion con yodo.
DE59309615D1 (de) Vorrichtung zum Pumpen von Blut
DE50105185D1 (de) Verfahren zur Herstellung von Dithiazolyldisulfiden
DE69029471D1 (de) Wiedergewinnungsverfahren von mikrobiell erzeugtem chymosin
DE69917245D1 (de) Betablocker enthaltende ophtalmische zusammensetzungen
DE59104247D1 (de) Verfahren zur Racemisierung von optisch aktiven 1-Aryl-alkylaminen.
DE60104832D1 (de) Behandlungsanlage zur flüssigkeitsbearbeitung von kontaktlinsen
DE69024806T3 (de) Methode der Reinigung von Proteinen
DE60234811D1 (de) Verfahren und zusammensetzungen zur extraktion von proteinen aus zellen
DK0523406T3 (da) Anvendelse af tri-(n-butyl)-phosphat ved lavt pH i opløsninger af biologisk aktive proteiner til forøget virucid virkning
DK0512087T3 (da) Fremgangsmåde til reaktivering af denaturerede proteiner
DE3775853D1 (de) Verfahren zur behandlung von kontaktlinsen.
ATE76586T1 (de) Loesungen amphoterer tenside zur reinigung oder konservierung von weichkontaktlinsen.
NO2006006I1 (no) Aktivert protein C
ATE249837T1 (de) Caspase 8-inhibitoren zur immunsuppression
DE60028750D1 (de) Verwendung von tagatose zur verbesserung wichtiger blutfaktoren