DK1373230T3 - Enantiselektiv syntese af azetidinon mellemprodukter - Google Patents

Enantiselektiv syntese af azetidinon mellemprodukter

Info

Publication number
DK1373230T3
DK1373230T3 DK02728561T DK02728561T DK1373230T3 DK 1373230 T3 DK1373230 T3 DK 1373230T3 DK 02728561 T DK02728561 T DK 02728561T DK 02728561 T DK02728561 T DK 02728561T DK 1373230 T3 DK1373230 T3 DK 1373230T3
Authority
DK
Denmark
Prior art keywords
enantiselective
synthesis
azetidinone intermediates
azetidinone
intermediates
Prior art date
Application number
DK02728561T
Other languages
English (en)
Inventor
Chou-Hong Tann
Xiaoyong Fu
Timothy L Mcallister
T K Thiruvengadam
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK1373230T3 publication Critical patent/DK1373230T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/26—Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK02728561T 2001-03-28 2002-03-25 Enantiselektiv syntese af azetidinon mellemprodukter DK1373230T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27928801P 2001-03-28 2001-03-28

Publications (1)

Publication Number Publication Date
DK1373230T3 true DK1373230T3 (da) 2005-11-07

Family

ID=23068350

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02728561T DK1373230T3 (da) 2001-03-28 2002-03-25 Enantiselektiv syntese af azetidinon mellemprodukter

Country Status (28)

Country Link
US (1) US6627757B2 (da)
EP (1) EP1373230B1 (da)
JP (1) JP4145663B2 (da)
KR (1) KR100590342B1 (da)
CN (1) CN1275949C (da)
AT (1) ATE305459T1 (da)
AU (1) AU2002258605B2 (da)
BG (1) BG66189B1 (da)
BR (1) BRPI0208384B1 (da)
CA (1) CA2442219C (da)
CZ (1) CZ304929B6 (da)
DE (1) DE60206365T2 (da)
DK (1) DK1373230T3 (da)
EA (1) EA006898B1 (da)
EE (1) EE05453B1 (da)
ES (1) ES2245733T3 (da)
HR (1) HRP20030760B1 (da)
HU (1) HU230229B1 (da)
IL (2) IL157552A0 (da)
MX (1) MXPA03008803A (da)
NZ (1) NZ527852A (da)
PL (1) PL205952B1 (da)
RS (1) RS50386B (da)
SI (1) SI1373230T1 (da)
SK (1) SK287408B6 (da)
UA (1) UA75644C2 (da)
WO (1) WO2002079174A2 (da)
ZA (1) ZA200306612B (da)

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Also Published As

Publication number Publication date
CZ304929B6 (cs) 2015-01-28
IL157552A0 (en) 2004-03-28
JP2004532210A (ja) 2004-10-21
CA2442219C (en) 2007-09-11
SI1373230T1 (sl) 2005-12-31
CA2442219A1 (en) 2002-10-10
KR100590342B1 (ko) 2006-06-15
EE05453B1 (et) 2011-08-15
ATE305459T1 (de) 2005-10-15
CN1500083A (zh) 2004-05-26
US6627757B2 (en) 2003-09-30
JP4145663B2 (ja) 2008-09-03
EE200300464A (et) 2003-12-15
SK287408B6 (sk) 2010-09-07
CN1275949C (zh) 2006-09-20
PL205952B1 (pl) 2010-06-30
PL363864A1 (en) 2004-11-29
YU74803A (sh) 2006-05-25
HUP0303526A2 (hu) 2004-01-28
MXPA03008803A (es) 2004-02-18
BG66189B1 (bg) 2011-12-30
DE60206365D1 (de) 2005-11-03
HK1057546A1 (en) 2004-04-08
RS50386B (sr) 2009-12-31
ZA200306612B (en) 2004-10-12
HRP20030760B1 (hr) 2011-07-31
BG108168A (en) 2004-09-30
EP1373230A2 (en) 2004-01-02
WO2002079174A3 (en) 2003-02-27
HUP0303526A3 (en) 2004-11-29
US20020193607A1 (en) 2002-12-19
SK11862003A3 (sk) 2004-04-06
NZ527852A (en) 2005-03-24
IL157552A (en) 2009-08-03
CZ20032610A3 (en) 2004-03-17
AU2002258605B2 (en) 2006-01-12
EP1373230B1 (en) 2005-09-28
BRPI0208384B1 (pt) 2016-05-31
EA200300970A1 (ru) 2004-04-29
BR0208384A (pt) 2004-06-15
WO2002079174A2 (en) 2002-10-10
EA006898B1 (ru) 2006-04-28
HU230229B1 (hu) 2015-10-28
ES2245733T3 (es) 2006-01-16
KR20030085573A (ko) 2003-11-05
DE60206365T2 (de) 2006-07-06
UA75644C2 (en) 2006-05-15
HRP20030760A2 (en) 2004-08-31

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