DK13788A - Fremgangsmaade til fremstilling af et polypeptid - Google Patents

Fremgangsmaade til fremstilling af et polypeptid

Info

Publication number
DK13788A
DK13788A DK013788A DK13788A DK13788A DK 13788 A DK13788 A DK 13788A DK 013788 A DK013788 A DK 013788A DK 13788 A DK13788 A DK 13788A DK 13788 A DK13788 A DK 13788A
Authority
DK
Denmark
Prior art keywords
pct
polypeptide
secretion sequence
terminal secretion
preparing
Prior art date
Application number
DK013788A
Other languages
English (en)
Other versions
DK13788D0 (da
Inventor
Ian Barry Holland
Nigel Mackman
Jean-Marc Nicaud
Original Assignee
Ian Barry Holland
Nigel Mackman
Nicaud Jean Marc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ian Barry Holland, Nigel Mackman, Nicaud Jean Marc filed Critical Ian Barry Holland
Publication of DK13788D0 publication Critical patent/DK13788D0/da
Publication of DK13788A publication Critical patent/DK13788A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478Aspartic endopeptidases (3.4.23)
    • C12N9/6481Pepsins (3.4.23.1; 3.4.23.2; 3.4.23.3)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/61Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK013788A 1986-05-15 1988-01-13 Fremgangsmaade til fremstilling af et polypeptid DK13788A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB868611832A GB8611832D0 (en) 1986-05-15 1986-05-15 Polypeptide
PCT/GB1987/000331 WO1987006953A1 (en) 1986-05-15 1987-05-14 Process for the production of a polypeptide

Publications (2)

Publication Number Publication Date
DK13788D0 DK13788D0 (da) 1988-01-13
DK13788A true DK13788A (da) 1988-03-15

Family

ID=10597902

Family Applications (1)

Application Number Title Priority Date Filing Date
DK013788A DK13788A (da) 1986-05-15 1988-01-13 Fremgangsmaade til fremstilling af et polypeptid

Country Status (9)

Country Link
US (1) US5143830A (da)
EP (1) EP0267224B1 (da)
JP (1) JPS63503274A (da)
AT (1) ATE80660T1 (da)
AU (1) AU600949B2 (da)
DE (1) DE3781765T2 (da)
DK (1) DK13788A (da)
GB (2) GB8611832D0 (da)
WO (1) WO1987006953A1 (da)

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GB8611832D0 (en) 1986-06-25
JPS63503274A (ja) 1988-12-02
DE3781765D1 (de) 1992-10-22
EP0267224A1 (en) 1988-05-18
US5143830A (en) 1992-09-01
WO1987006953A1 (en) 1987-11-19
GB8800141D0 (en) 1988-03-02
GB2197324B (en) 1990-04-11
ATE80660T1 (de) 1992-10-15
AU600949B2 (en) 1990-08-30
DE3781765T2 (de) 1993-04-22
EP0267224B1 (en) 1992-09-16
DK13788D0 (da) 1988-01-13
GB2197324A (da) 1988-05-18
AU7392387A (en) 1987-12-01

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