DK1467998T3 - Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer - Google Patents

Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer

Info

Publication number
DK1467998T3
DK1467998T3 DK02797167T DK02797167T DK1467998T3 DK 1467998 T3 DK1467998 T3 DK 1467998T3 DK 02797167 T DK02797167 T DK 02797167T DK 02797167 T DK02797167 T DK 02797167T DK 1467998 T3 DK1467998 T3 DK 1467998T3
Authority
DK
Denmark
Prior art keywords
estrogen receptor
receptor modulators
hetero compounds
tetracyclic
tetracyclic hetero
Prior art date
Application number
DK02797167T
Other languages
Danish (da)
English (en)
Inventor
Ramesh M Kanojia
Nareshkumar F Jain
Raymond Ng
Zhihua Sui
Jiayi Xu
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1467998T3 publication Critical patent/DK1467998T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
DK02797167T 2001-12-19 2002-12-02 Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer DK1467998T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34195701P 2001-12-19 2001-12-19

Publications (1)

Publication Number Publication Date
DK1467998T3 true DK1467998T3 (da) 2006-07-31

Family

ID=23339719

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02797167T DK1467998T3 (da) 2001-12-19 2002-12-02 Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer

Country Status (21)

Country Link
EP (1) EP1467998B1 (de)
JP (1) JP2005513133A (de)
CN (1) CN1620457A (de)
AR (1) AR038661A1 (de)
AT (1) ATE321764T1 (de)
AU (1) AU2002362041A1 (de)
BR (1) BR0215152A (de)
CA (1) CA2471107A1 (de)
CY (1) CY1105361T1 (de)
DE (1) DE60210333T2 (de)
DK (1) DK1467998T3 (de)
ES (1) ES2264737T3 (de)
HU (1) HUP0500103A3 (de)
IL (1) IL162295A0 (de)
MX (1) MXPA04006034A (de)
NZ (1) NZ533281A (de)
PL (1) PL371045A1 (de)
PT (1) PT1467998E (de)
RU (1) RU2305099C2 (de)
WO (1) WO2003053977A1 (de)
ZA (1) ZA200405653B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7329654B2 (en) * 2001-12-19 2008-02-12 Janssen Pharmaceutica N.V. Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
US7105679B2 (en) 2001-12-19 2006-09-12 Kanojia Ramesh M Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
EP1713820A1 (de) * 2004-01-22 2006-10-25 Eli Lilly And Company Selektive östrogen-rezeptor-modulatoren
AU2005300030B2 (en) 2004-09-20 2012-01-12 Janssen Pharmaceutica N.V. Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators
MX2007016160A (es) 2005-06-15 2008-03-07 Fibrogen Inc Uso de moduladoers de hif-1 alfa para el tratamiento contra el cancer.
DE102006024032A1 (de) * 2006-05-23 2007-11-29 Voith Patent Gmbh Anordnung zur Bandregelung
RU2360670C1 (ru) * 2007-10-03 2009-07-10 Закрытое акционерное общество "Биологические исследования и системы" Фармацевтическая композиция для местного и наружного применения при климактерических расстройствах на основе сигетина
RS56042B1 (sr) * 2010-06-10 2017-09-29 Seragon Pharmaceuticals Inc Modulatori estrogenih receptora i njihove upotrebe
WO2013090829A1 (en) * 2011-12-14 2013-06-20 Aragon Pharmaceuticals, Inc. Estrogen receptor modulators and uses thereof
CN113135884B (zh) * 2020-01-20 2023-03-10 西华大学 一种异色烯类化合物及其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL124481C (de) * 1964-11-04
SU1607348A1 (ru) * 1989-03-02 1994-09-30 Пятигорский фармацевтический институт 7-(3-фенилпропеноилокси)- 4' -фторизофлавон, обладающий гипотензивным действием
CA2214196A1 (en) * 1996-09-26 1998-03-26 Eli Lilly And Company Benzo[b]indeno[2,1-d]thiophene compounds, intermediates, processes, compositions and methods
US6153768A (en) * 1996-12-13 2000-11-28 C & C Research Laboratories Benzopyran derivatives
RU2138669C1 (ru) * 1997-07-02 1999-09-27 Гнедых Александр Михайлович Воздушный ракетный двигатель

Also Published As

Publication number Publication date
CA2471107A1 (en) 2003-07-03
ES2264737T3 (es) 2007-01-16
HUP0500103A3 (en) 2009-01-28
EP1467998B1 (de) 2006-03-29
JP2005513133A (ja) 2005-05-12
MXPA04006034A (es) 2005-03-31
BR0215152A (pt) 2004-10-19
AR038661A1 (es) 2005-01-26
PL371045A1 (en) 2005-06-13
NZ533281A (en) 2007-05-31
ATE321764T1 (de) 2006-04-15
DE60210333T2 (de) 2006-11-30
WO2003053977A1 (en) 2003-07-03
CN1620457A (zh) 2005-05-25
DE60210333D1 (de) 2006-05-18
RU2004118606A (ru) 2006-01-10
HK1068875A1 (en) 2005-05-06
CY1105361T1 (el) 2010-03-03
AU2002362041A1 (en) 2003-07-09
PT1467998E (pt) 2006-08-31
RU2305099C2 (ru) 2007-08-27
EP1467998A1 (de) 2004-10-20
IL162295A0 (en) 2005-11-20
HUP0500103A2 (hu) 2005-05-30
ZA200405653B (en) 2006-06-28

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