DK1555265T3 - 7-phenylpyrazolopyridin-forbindelser - Google Patents

7-phenylpyrazolopyridin-forbindelser

Info

Publication number: DK1555265T3
Authority: DK; Denmark
Prior art keywords: phenylpyrazolopyridin; compounds; compound; äwherein; tetrahydropyranyl
Prior art date: 2002-10-22

Application number

DK03758781T

Other languages

English (en)

Inventor

Shigeki Hibi

Yorihisa Hoshino

Koichi Kikuchi

Kogyoku Shin

Yoshinori Takahashi

Masae Fujisawa

Hisashi Shibata

Mitsuhiro Ino

Original Assignee

Eisai R&D Man Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-22

Filing date

2003-10-22

Publication date

2009-06-22

2003-10-22 Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd

2009-06-22 Application granted granted Critical

2009-06-22 Publication of DK1555265T3 publication Critical patent/DK1555265T3/da

Links

FMVFEDWZIRSTGL-UHFFFAOYSA-N 7-phenyl-1h-pyrazolo[4,3-b]pyridine Chemical class C1=CN=C2C=NNC2=C1C1=CC=CC=C1 FMVFEDWZIRSTGL-UHFFFAOYSA-N 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
-1 methoxy, methylthio, ethyl Chemical group 0.000 abstract 2
125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
108010056643 Corticotropin-Releasing Hormone Receptors Proteins 0.000 abstract 1
102100038018 Corticotropin-releasing factor receptor 1 Human genes 0.000 abstract 1
230000008485 antagonism Effects 0.000 abstract 1
125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
125000004184 methoxymethyl group Chemical group [H]C([H])([H])OC([H])([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Otolaryngology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Plural Heterocyclic Compounds (AREA)

DK03758781T 2002-10-22 2003-10-22 7-phenylpyrazolopyridin-forbindelser DK1555265T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP2002306695		2002-10-22
US42107102P	2002-10-25	2002-10-25
PCT/JP2003/013490 WO2004037822A1 (ja)	2002-10-22	2003-10-22	７−フェニルピラゾロピリジン化合物

Publications (1)

Publication Number	Publication Date
DK1555265T3 true DK1555265T3 (da)	2009-06-22

Family

ID=32179072

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK03758781T DK1555265T3 (da)	2002-10-22	2003-10-22	7-phenylpyrazolopyridin-forbindelser

Country Status (21)

Country	Link
US (2)	US7323569B2 (da)
EP (1)	EP1555265B1 (da)
JP (1)	JP4322211B2 (da)
KR (1)	KR100984085B1 (da)
AT (1)	ATE426600T1 (da)
AU (1)	AU2003275589B2 (da)
BR (1)	BRPI0313976B8 (da)
CA (1)	CA2494574C (da)
CY (1)	CY1110319T1 (da)
DE (1)	DE60326869D1 (da)
DK (1)	DK1555265T3 (da)
ES (1)	ES2322143T3 (da)
MX (1)	MXPA05002185A (da)
NO (1)	NO331294B1 (da)
NZ (1)	NZ538860A (da)
PL (1)	PL213633B1 (da)
PT (1)	PT1555265E (da)
RU (1)	RU2327699C2 (da)
SI (1)	SI1555265T1 (da)
TW (1)	TWI283679B (da)
WO (1)	WO2004037822A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TWI312347B (en)	2001-02-08	2009-07-21	Eisai R&D Man Co Ltd	Bicyclic nitrogen-containing condensed ring compounds
SI1555265T1 (sl) *	2002-10-22	2009-06-30	Eisai R&D Man Co Ltd	7-fenil pirazolopiridinske spojine
CA2562578C (en) *	2004-04-12	2013-04-02	Eisai R&D Management Co., Ltd.	Process for production of pyrazole-fused ring derivatives
CN102532180B (zh) *	2005-12-30	2016-06-29	安纳考尔医药公司	含硼的小分子
RU2357729C2 (ru) *	2007-05-21	2009-06-10	Эльвира Ивановна Белобородова	Способ лечения язвенной болезни двенадцатиперстной кишки, осложненной коморбидными тревожно-депрессивными расстройствами
JPWO2009051210A1 (ja) *	2007-10-18	2011-03-03	エーザイ・アール・アンド・ディー・マネジメント株式会社	ピラゾール縮合環誘導体の製造方法
RS52561B (sr) *	2008-04-15	2013-04-30	Eisai R&D Management Co., Ltd.	Jedinjenje 3-fenilpirazolo[5,1-b]tiazol
JPWO2011043387A1 (ja) *	2009-10-08	2013-03-04	エーザイ・アール・アンド・ディー・マネジメント株式会社	ピラゾロオキサゾール化合物
AR078521A1 (es) *	2009-10-08	2011-11-16	Eisai R&D Man Co Ltd	Compuesto pirazolotiazol
WO2014009305A1 (en) *	2012-07-09	2014-01-16	Janssen Pharmaceutica Nv	Inhibitors of phosphodiesterase 10 enzyme
CN108373479B (zh) *	2015-08-14	2020-06-12	南京中硼联康医疗科技有限公司	L-bpa的制备方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4925849A (en)	1987-06-15	1990-05-15	Fujisawa Pharmaceutical Company, Ltd.	Pharmaceutically useful pyrazolopyridines
US5338743A (en)	1988-06-06	1994-08-16	Fujisawa Pharmaceutical Co., Ltd.	New use of the adenosine antagonist
JPH085790B2 (ja) *	1988-11-11	1996-01-24	杏林製薬株式会社	記憶障害改善薬
DE3942356A1 (de)	1989-12-21	1991-06-27	Boehringer Mannheim Gmbh	Verwendung von 1-arylsemicarbaziden zur stabilisierung von enzymsubstraten, entsprechende verfahren und diagnostisches mittel enthaltend einen solchen stabilisator
DE3942357A1 (de)	1989-12-21	1991-06-27	Boehringer Mannheim Gmbh	3-aminopyrazolo-heterocyclen, deren verwendung zur bestimmung von wasserstoffperoxid, wasserstoffperoxid-bildenden systemen, peroxidase, peroxidatisch wirksamen substanzen oder von elektronenreichen aromatischen verbindungen, entsprechende bestimmungsverfahren und hierfuer geeignete mittel
FR2687675B1 (fr)	1992-01-31	1997-04-18	Roussel Uclaf	Nouveaux derives bicycliques de la pyridine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DE69323883T2 (de)	1992-06-17	1999-07-22	Pharmacia & Upjohn Co., Kalamazoo, Mich.	Pyrridino-, pyrrolidino- und azepino-substituierte oxime als antiatherosklerosemittel und antihypercholesterolemiemittel
TW336932B (en)	1992-12-17	1998-07-21	Pfizer	Amino-substituted pyrazoles
DK0674624T3 (da)	1992-12-17	1999-09-13	Pfizer	Pyrazoler med CRF-antagonistisk aktivitet
ATE177101T1 (de)	1992-12-17	1999-03-15	Pfizer	Pyrrolopyrimidine als crf antagonisten
TW370529B (en)	1992-12-17	1999-09-21	Pfizer	Pyrazolopyrimidines
KR100190730B1 (ko)	1992-12-17	1999-06-01	디. 제이. 우드, 스피겔 알렌 제이	부신피질 호르몬 유리인자(crf) 길항물질로서 치환된 피라졸
FR2701708B1 (fr)	1993-02-19	1995-05-19	Sanofi Elf	Dérivés de 2-amido-4-phénylthiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament.
DE4311460A1 (de)	1993-04-08	1994-10-13	Boehringer Mannheim Gmbh	Verfahren zur kolorimetrischen Bestimmung eines Analyten mittels Benzylalkoholdehydrogenase und einem chromogenen Redoxindikator
RU2153494C2 (ru)	1993-10-12	2000-07-27	Дзе Дюпон Мерк Фармасьютикал Компани	1-n-алкил-n-арилпиримидинамины, способ лечения заболеваний, фармацевтическая композиция
FR2714059B1 (fr)	1993-12-21	1996-03-08	Sanofi Elf	Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
WO1995034563A1 (en)	1994-06-16	1995-12-21	Pfizer Inc.	Pyrazolo and pyrrolopyridines
ES2167710T3 (es)	1996-02-07	2002-05-16	Janssen Pharmaceutica Nv	Tiofenopirimidinas.
JP3356291B2 (ja)	1996-02-07	2002-12-16	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	Ｃｒｆレセプター拮抗薬としてのピラゾロピリミジン類
US6022978A (en)	1996-06-11	2000-02-08	Pfizer Inc.	Benzimidazole derivatives
IL127566A0 (en)	1996-08-28	1999-10-28	Pfizer	Substituted 6,5-hetero- bicyclic derivatives
JP2001511813A (ja)	1997-02-18	2001-08-14	ニューロクラインバイオサイエンシーズ，インコーポレイテッド	Ｃｒｆレセプターアンタゴニストおよびそれらに関連する方法
PL337888A1 (en)	1997-07-03	2000-09-11	Du Pont Pharm Co	Imidazoprimidines and imidazopyridines for use in treating neurological disorders
AU9021598A (en)	1997-08-22	1999-03-16	Du Pont Pharmaceuticals Company	Nitrogen substituted imidazo{4,5-c}pyrazoles as corticotropin relea sing hormone antagonists
US6365589B1 (en)	1998-07-02	2002-04-02	Bristol-Myers Squibb Pharma Company	Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
US6271380B1 (en)	1998-12-30	2001-08-07	Dupont Pharmaceuticals Company	1H-imidazo[4,5-d]pyridazin-7-ones, 3H-imidazo-[4,5-c]pyridin-4-ones and corresponding thiones as corticotropin releasing factor (CRF) receptor ligands
WO2000059908A2 (en)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolopyrimidines as crf antagonists
WO2000059907A2 (en)	1999-04-06	2000-10-12	Du Pont Pharmaceuticals Company	Pyrazolotriazines as crf antagonists
JP3795305B2 (ja) *	1999-07-19	2006-07-12	田辺製薬株式会社	医薬組成物
FR2801308B1 (fr)	1999-11-19	2003-05-09	Oreal	COMPOSITIONS DE TEINTURE DE FIBRES KERATINIQUES CONTENANT DE DES 3-AMINO PYRAZOLO-[1,(-a]-PYRIDINES, PROCEDE DE TEINTURE, NOUVELLES 3-AMINO PYRAZOLO-[1,5-a]-PYRIDINES
EP1244666A1 (en)	1999-12-17	2002-10-02	Bristol-Myers Squibb Pharma Company	Imidazopyrimidinyl and imidazopyridinyl derivatives
WO2002006286A2 (en)	2000-07-14	2002-01-24	Bristol-Myers Squibb Pharma Company	IMIDAZO[1,2-a]PYRAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
MY129000A (en)	2000-08-31	2007-03-30	Tanabe Seiyaku Co	INHIBITORS OF a4 MEDIATED CELL ADHESION
KR20040034594A (ko)	2001-01-26	2004-04-28	브리스톨-마이어스스퀴브컴파니	코르티코트로핀 방출 인자 억제제로서의 이미다졸릴 유도체
WO2002088121A1 (en) *	2001-04-27	2002-11-07	Eisai Co., Ltd.	Pyrazolo[1,5-a]pyridines and medicines containing the same
MY140707A (en)	2002-02-28	2010-01-15	Mitsubishi Tanabe Pharma Corp	Process for preparing a phenylalanine derivative and intermediates thereof
CA2478715A1 (en) *	2002-03-13	2003-09-25	Pharmacia & Upjohn Company	Novel pyrazolo [1,5-a]pyridine derivatives and their use as neurotransmitter modulators
US7176216B2 (en)	2002-10-22	2007-02-13	Eisai Co., Ltd.	7-phenylpyrazolopyridine compounds
SI1555265T1 (sl) *	2002-10-22	2009-06-30	Eisai R&D Man Co Ltd	7-fenil pirazolopiridinske spojine

2003
- 2003-10-22 SI SI200331567T patent/SI1555265T1/sl unknown
- 2003-10-22 WO PCT/JP2003/013490 patent/WO2004037822A1/ja not_active Ceased
- 2003-10-22 JP JP2004546447A patent/JP4322211B2/ja not_active Expired - Lifetime
- 2003-10-22 NZ NZ538860A patent/NZ538860A/en not_active IP Right Cessation
- 2003-10-22 TW TW092129327A patent/TWI283679B/zh not_active IP Right Cessation
- 2003-10-22 BR BRPI0313976A patent/BRPI0313976B8/pt not_active IP Right Cessation
- 2003-10-22 ES ES03758781T patent/ES2322143T3/es not_active Expired - Lifetime
- 2003-10-22 US US10/524,662 patent/US7323569B2/en not_active Expired - Lifetime
- 2003-10-22 KR KR1020057006800A patent/KR100984085B1/ko not_active Expired - Fee Related
- 2003-10-22 EP EP03758781A patent/EP1555265B1/en not_active Expired - Lifetime
- 2003-10-22 RU RU2005115504/04A patent/RU2327699C2/ru active
- 2003-10-22 DE DE60326869T patent/DE60326869D1/de not_active Expired - Lifetime
- 2003-10-22 MX MXPA05002185A patent/MXPA05002185A/es active IP Right Grant
- 2003-10-22 AT AT03758781T patent/ATE426600T1/de active
- 2003-10-22 CA CA2494574A patent/CA2494574C/en not_active Expired - Lifetime
- 2003-10-22 PL PL376132A patent/PL213633B1/pl unknown
- 2003-10-22 PT PT03758781T patent/PT1555265E/pt unknown
- 2003-10-22 DK DK03758781T patent/DK1555265T3/da active
- 2003-10-22 AU AU2003275589A patent/AU2003275589B2/en not_active Expired
2005
- 2005-05-20 NO NO20052443A patent/NO331294B1/no not_active IP Right Cessation
2007
- 2007-09-20 US US11/858,160 patent/US20080076943A1/en not_active Abandoned
2009
- 2009-06-12 CY CY20091100625T patent/CY1110319T1/el unknown

Also Published As

Publication number	Publication date
HK1081536A1 (zh)	2006-05-19
SI1555265T1 (sl)	2009-06-30
NZ538860A (en)	2006-07-28
US7323569B2 (en)	2008-01-29
BRPI0313976B8 (pt)	2021-05-25
WO2004037822A1 (ja)	2004-05-06
EP1555265A4 (en)	2006-08-02
ATE426600T1 (de)	2009-04-15
BRPI0313976B1 (pt)	2018-12-26
JP4322211B2 (ja)	2009-08-26
JPWO2004037822A1 (ja)	2006-02-23
EP1555265A1 (en)	2005-07-20
TWI283679B (en)	2007-07-11
TW200427687A (en)	2004-12-16
AU2003275589B2 (en)	2009-05-28
NO20052443L (no)	2005-07-22
US20080076943A1 (en)	2008-03-27
CA2494574C (en)	2011-05-17
PL376132A1 (en)	2005-12-27
PT1555265E (pt)	2009-05-12
AU2003275589A1 (en)	2004-05-13
CY1110319T1 (el)	2015-01-14
MXPA05002185A (es)	2005-05-23
RU2005115504A (ru)	2006-01-20
ES2322143T3 (es)	2009-06-17
BR0313976A (pt)	2005-07-19
PL213633B1 (pl)	2013-04-30
US20060235011A1 (en)	2006-10-19
KR100984085B1 (ko)	2010-09-30
RU2327699C2 (ru)	2008-06-27
NO20052443D0 (no)	2005-05-20
EP1555265B1 (en)	2009-03-25
NO331294B1 (no)	2011-11-21
CA2494574A1 (en)	2004-05-06
DE60326869D1 (de)	2009-05-07
KR20050070069A (ko)	2005-07-05

Publication	Publication Date	Title
CY1110319T1 (el)	2015-01-14	Ενωσεις 7-φενυλ πυραζολοπυριδινης
EP1720881B8 (en)	2013-01-16	11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-one derivatives as key intermediates for the preparation of c2 substituted pyrrolobenzodiazepins
DE60230266D1 (de)	2009-01-22	Phenylpyridincarbonyl piperazinderivate
ATE211735T1 (de)	2002-01-15	1-phenyl-pyrazolderivate und ihr verwendung als schädlingsbekämpfungsmittel
NO20034595D0 (no)	2003-10-14	Kinolin- og kinazolinderivater med azolylgruppe
AP1902A (en)	2008-10-15	N-aryl-2-oxazolidinone-5-carboxamides and their derivatives and their use as antibacterials
WO2004014913A3 (en)	2004-07-29	Derivatives of 2-trifluormethyl-6-aminopurine as phosphodiesterase 4 inhibitors
DE602004012559D1 (de)	2008-04-30	4-SUBSTITUIERTE DERIVATE VON PYRAZOLOi3,4-D PYRIMIDIN UND DEREN VERWENDUNGEN
MXPA06000185A (es)	2006-04-11	Derivados de quinazolinas 5-sustituidas.
DK1364959T3 (da)	2007-06-04	Krystallinske former af pyrimidinnukleosidderivater
DE60103129D1 (de)	2004-06-09	Benzofurancarboxamide und deren therapeutische verwendung
DE60330038D1 (de)	2009-12-24	Neue alpha-ketoamidderivate und deren verwendung
DE60211018D1 (de)	2006-06-01	Fungizide thiazolderivate
DE60322856D1 (da)	2008-09-25