DK167342B1 - Terapeutisk praeparat til behandling af virussygdomme samt anvendelse af et 9-(fosfonylmetoxyalkyl)adeninderivat til fremstilling af praeparatet - Google Patents

Terapeutisk praeparat til behandling af virussygdomme samt anvendelse af et 9-(fosfonylmetoxyalkyl)adeninderivat til fremstilling af praeparatet Download PDF

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Publication number
DK167342B1
DK167342B1 DK184186A DK184186A DK167342B1 DK 167342 B1 DK167342 B1 DK 167342B1 DK 184186 A DK184186 A DK 184186A DK 184186 A DK184186 A DK 184186A DK 167342 B1 DK167342 B1 DK 167342B1
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Prior art keywords
preparation
compounds
formula
compound
treatment
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DK184186A
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Danish (da)
English (en)
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DK184186A (da
DK184186D0 (da
Inventor
Erik De Clercq
Antonin Holy
Ivan Rosenberg
Original Assignee
Stichting Rega V Z W
Ceskoslovenska Akademie Ved
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Application filed by Stichting Rega V Z W, Ceskoslovenska Akademie Ved filed Critical Stichting Rega V Z W
Publication of DK184186D0 publication Critical patent/DK184186D0/da
Publication of DK184186A publication Critical patent/DK184186A/da
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
DK184186A 1985-04-25 1986-04-22 Terapeutisk praeparat til behandling af virussygdomme samt anvendelse af et 9-(fosfonylmetoxyalkyl)adeninderivat til fremstilling af praeparatet DK167342B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CS853018A CS263952B1 (en) 1985-04-25 1985-04-25 Remedy with antiviral effect
CS301885 1985-04-25

Publications (3)

Publication Number Publication Date
DK184186D0 DK184186D0 (da) 1986-04-22
DK184186A DK184186A (da) 1986-10-26
DK167342B1 true DK167342B1 (da) 1993-10-18

Family

ID=5369042

Family Applications (1)

Application Number Title Priority Date Filing Date
DK184186A DK167342B1 (da) 1985-04-25 1986-04-22 Terapeutisk praeparat til behandling af virussygdomme samt anvendelse af et 9-(fosfonylmetoxyalkyl)adeninderivat til fremstilling af praeparatet

Country Status (17)

Country Link
US (1) US4724233A (cs)
EP (1) EP0205826B1 (cs)
JP (1) JPH0692307B2 (cs)
AT (1) ATE73663T1 (cs)
AU (1) AU586860B2 (cs)
CA (1) CA1272956A (cs)
CS (1) CS263952B1 (cs)
DE (1) DE3684363D1 (cs)
DK (1) DK167342B1 (cs)
EG (1) EG18436A (cs)
GR (1) GR861089B (cs)
HK (1) HK217296A (cs)
IL (1) IL78553A (cs)
NZ (1) NZ215939A (cs)
PH (1) PH23112A (cs)
PT (1) PT82457B (cs)
ZA (1) ZA863133B (cs)

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DK0481214T3 (da) * 1990-09-14 1999-02-22 Acad Of Science Czech Republic Prolægemidler af phosphonater
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US6057305A (en) 1992-08-05 2000-05-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Antiretroviral enantiomeric nucleotide analogs
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US5468752A (en) * 1994-04-04 1995-11-21 Freeman; William R. Treatment of conditions of abnormally increased intraocular pressure by administration of HPMPC and related phosphonylmethoxyalkylcytosines
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
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US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US20030187261A1 (en) * 2000-01-07 2003-10-02 Libor Havlicek Purine derivatives, process for their preparation and use thereof
HRP20030047B1 (hr) 2000-07-21 2016-02-26 Gilead Sciences, Inc. Prolijekovi koji su fosfonatni analozi nukleotida i metode njihovog odabira te njihova priprava
BRPI0210746B8 (pt) 2001-06-29 2021-05-25 Inst Of Organic Chemistry And Biochemistry Ascr derivados de 6-'2-(fosfonometóxi)alcóxi-pirimidina e seu método de preparação
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AU2003235501A1 (en) * 2002-05-13 2003-11-11 Metabasis Therapeutics, Inc. PMEA and PMPA cyclic producing synthesis
RU2225223C1 (ru) * 2002-06-14 2004-03-10 Закрытое акционерное общество Фирма "ВИТАФАРМА" Лиофилизированная антигерпетическая вакцина
WO2004043972A1 (fr) * 2002-11-12 2004-05-27 Tianjin Kinsly Pharmaceutical Co., Ltd. Nouvelle forme cristalline d'adefovir dipivoxil et sa composition
PT1583542E (pt) 2003-01-14 2008-09-17 Gilead Sciences Inc Composições e métodos para terapia de combinação antiviral
NZ543864A (en) 2003-06-16 2009-10-30 Leuven K U Res & Dev Pyrimidine compounds having phosphonate groups as antiviral nucleotide analogs
MXPA06014013A (es) * 2004-06-08 2007-03-15 Metabasis Therapeutics Inc Sintesis mediada por acidos de lewis de esteres ciclicos.
CN100338080C (zh) * 2004-06-16 2007-09-19 山东中科泰斗化学有限公司 9-[2-(膦羧基甲氧基)乙基]腺嘌呤双环醇酯及其制备方法
PT2258376T (pt) 2004-07-27 2019-05-31 Gilead Sciences Inc Análogos fosfonatados de compostos inibidores do vih
US8101745B2 (en) * 2004-12-16 2012-01-24 The Regents Of The University Of California Lung-targeted drugs
US20090156545A1 (en) * 2005-04-01 2009-06-18 Hostetler Karl Y Substituted Phosphate Esters of Nucleoside Phosphonates
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FR2908133B1 (fr) * 2006-11-08 2012-12-14 Centre Nat Rech Scient Nouveaux analogues de nucleotides comme molecules precurseurs d'antiviraux
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CS238038B1 (en) * 1983-10-07 1985-11-13 Antonin Holy Medical drug with antivirus effect

Also Published As

Publication number Publication date
ZA863133B (en) 1987-02-25
PH23112A (en) 1989-04-19
AU586860B2 (en) 1989-07-27
ATE73663T1 (de) 1992-04-15
EP0205826B1 (en) 1992-03-18
IL78553A (en) 1989-09-28
EP0205826A2 (en) 1986-12-30
EG18436A (en) 1993-02-28
HK217296A (en) 1996-12-27
DK184186A (da) 1986-10-26
CA1272956A (en) 1990-08-21
DE3684363D1 (de) 1992-04-23
NZ215939A (en) 1988-09-29
AU5646886A (en) 1986-10-30
PT82457B (pt) 1988-03-03
JPH0692307B2 (ja) 1994-11-16
IL78553A0 (en) 1986-08-31
JPS61275218A (ja) 1986-12-05
US4724233A (en) 1988-02-09
DK184186D0 (da) 1986-04-22
GR861089B (en) 1986-08-26
EP0205826A3 (en) 1989-05-10
CS263952B1 (en) 1989-05-12
PT82457A (en) 1986-05-01

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B1 Patent granted (law 1993)
PUP Patent expired