DK169335B1 - N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum - Google Patents

N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum Download PDF

Info

Publication number: DK169335B1
Authority: DK; Denmark
Prior art keywords: compound; formula; acid addition; pharmaceutical; addition salt
Prior art date: 1987-06-23

Application number

DK340188A

Other languages

Danish (da)

English (en)

Other versions

DK340188A (da

DK340188D0 (da

Inventor

Walter Haefliger

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-23

Filing date

1988-06-21

Publication date

1994-10-10

1988-06-21 Application filed by Sandoz Ag filed Critical Sandoz Ag

1988-06-21 Publication of DK340188D0 publication Critical patent/DK340188D0/da

1988-12-24 Publication of DK340188A publication Critical patent/DK340188A/da

1994-10-10 Application granted granted Critical

1994-10-10 Publication of DK169335B1 publication Critical patent/DK169335B1/da

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)

DK340188A 1987-06-23 1988-06-21 N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum DK169335B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3720656		1987-06-23
DE3720656		1987-06-23

Publications (3)

Publication Number	Publication Date
DK340188D0 DK340188D0 (da)	1988-06-21
DK340188A DK340188A (da)	1988-12-24
DK169335B1 true DK169335B1 (da)	1994-10-10

Family

ID=6330087

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK340188A DK169335B1 (da)	1987-06-23	1988-06-21	N-((5R,8S,10R)-2,6-dimethyl-ergolin-8-yl)-2-ethyl-2-methyl-butanamid, fremgangsmåde til fremstilling_deraf, farmaceutiske præparater indeholdende forbindelsen samt anvendelse af forbindelsen som farmaceutikum

Country Status (28)

Country	Link
US (1)	US5075318A (it)
JP (1)	JPH0670052B2 (it)
KR (1)	KR970001527B1 (it)
AT (1)	AT395242B (it)
AU (1)	AU615657B2 (it)
BE (1)	BE1004034A3 (it)
CA (1)	CA1302404C (it)
CH (1)	CH674646A5 (it)
CY (1)	CY1752A (it)
DK (1)	DK169335B1 (it)
ES (1)	ES2010282A6 (it)
FI (1)	FI88302C (it)
FR (1)	FR2617166B1 (it)
GB (1)	GB2206115B (it)
GR (1)	GR1002318B (it)
HK (1)	HK2794A (it)
HU (2)	HU203097B (it)
IE (1)	IE60550B1 (it)
IL (1)	IL86820A (it)
IT (1)	IT1219652B (it)
LU (1)	LU87251A1 (it)
MY (1)	MY103584A (it)
NL (1)	NL8801597A (it)
NZ (1)	NZ225112A (it)
PH (1)	PH24690A (it)
PT (1)	PT87781B (it)
SE (1)	SE467925B (it)
ZA (1)	ZA884505B (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL193541C (nl) *	1984-01-12	2000-01-04	Novartis Ag	8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
JP3630888B2 (ja) *	1996-10-31	2005-03-23	株式会社ニデック	レンズ搬送装置と眼鏡レンズを搬送するための眼鏡レンズ用固定カップ及びレンズ搬送方法
AU2009303389B2 (en)	2008-10-17	2014-10-16	Wisconsin Alumni Research Foundation	Method of making biologically active alpha-beta peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL193541C (nl) *	1984-01-12	2000-01-04	Novartis Ag	8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
CH666035A5 (de) *	1984-12-24	1988-06-30	Sandoz Ag	8-alpha-acylaminoergolene.

1988
- 1988-06-17 IT IT48097/88A patent/IT1219652B/it active
- 1988-06-20 FR FR888808357A patent/FR2617166B1/fr not_active Expired - Lifetime
- 1988-06-20 BE BE8800702A patent/BE1004034A3/fr not_active IP Right Cessation
- 1988-06-20 LU LU87251A patent/LU87251A1/fr unknown
- 1988-06-20 GB GB8814615A patent/GB2206115B/en not_active Expired - Lifetime
- 1988-06-21 HU HU883159A patent/HU203097B/hu not_active IP Right Cessation
- 1988-06-21 SE SE8802323A patent/SE467925B/sv not_active IP Right Cessation
- 1988-06-21 MY MYPI88000682A patent/MY103584A/en unknown
- 1988-06-21 IL IL86820A patent/IL86820A/xx not_active IP Right Cessation
- 1988-06-21 AU AU18194/88A patent/AU615657B2/en not_active Ceased
- 1988-06-21 PT PT87781A patent/PT87781B/pt not_active IP Right Cessation
- 1988-06-21 CH CH2387/88A patent/CH674646A5/de not_active IP Right Cessation
- 1988-06-21 GR GR880100401A patent/GR1002318B/el unknown
- 1988-06-21 IE IE186788A patent/IE60550B1/en not_active IP Right Cessation
- 1988-06-21 NZ NZ225112A patent/NZ225112A/en unknown
- 1988-06-21 DK DK340188A patent/DK169335B1/da not_active IP Right Cessation
- 1988-06-22 PH PH37103A patent/PH24690A/en unknown
- 1988-06-22 AT AT0161788A patent/AT395242B/de not_active IP Right Cessation
- 1988-06-22 FI FI883008A patent/FI88302C/fi not_active IP Right Cessation
- 1988-06-22 JP JP63154570A patent/JPH0670052B2/ja not_active Expired - Lifetime
- 1988-06-22 CA CA000570102A patent/CA1302404C/en not_active Expired - Lifetime
- 1988-06-22 KR KR1019880007511A patent/KR970001527B1/ko not_active Expired - Fee Related
- 1988-06-23 ZA ZA884505A patent/ZA884505B/xx unknown
- 1988-06-23 NL NL8801597A patent/NL8801597A/nl active Search and Examination
- 1988-06-23 ES ES8801948A patent/ES2010282A6/es not_active Expired
1990
- 1990-11-02 US US07/608,454 patent/US5075318A/en not_active Expired - Lifetime
1994
- 1994-01-13 HK HK27/94A patent/HK2794A/xx not_active IP Right Cessation
- 1994-06-03 CY CY175294A patent/CY1752A/en unknown
1995
- 1995-06-15 HU HU95P/P00209P patent/HU211651A9/hu unknown

Also Published As

Publication number	Publication date
FI88302B (fi)	1993-01-15
IE60550B1 (en)	1994-07-27
SE467925B (sv)	1992-10-05
NZ225112A (en)	1991-03-26
SE8802323D0 (sv)	1988-06-21
SE8802323L (sv)	1988-12-24
ES2010282A6 (es)	1989-11-01
FI883008L (fi)	1988-12-24
FR2617166A1 (fr)	1988-12-30
MY103584A (en)	1993-08-28
JPH0670052B2 (ja)	1994-09-07
GB2206115B (en)	1991-04-03
HU211651A9 (en)	1995-12-28
IE881867L (en)	1988-12-23
CY1752A (en)	1994-06-03
CH674646A5 (it)	1990-06-29
GB8814615D0 (en)	1988-07-27
AT395242B (de)	1992-10-27
AU1819488A (en)	1989-01-05
KR970001527B1 (ko)	1997-02-11
NL8801597A (nl)	1989-01-16
DK340188A (da)	1988-12-24
HUT50174A (en)	1989-12-28
CA1302404C (en)	1992-06-02
FR2617166B1 (fr)	1992-07-17
BE1004034A3 (fr)	1992-09-15
IT8848097A0 (it)	1988-06-17
PT87781A (pt)	1989-05-31
HK2794A (en)	1994-01-21
LU87251A1 (fr)	1989-03-08
PT87781B (pt)	1992-10-30
GR880100401A (el)	1989-03-08
AU615657B2 (en)	1991-10-10
ATA161788A (de)	1992-03-15
IT1219652B (it)	1990-05-24
PH24690A (en)	1990-09-07
KR890000479A (ko)	1989-03-14
US5075318A (en)	1991-12-24
HU203097B (en)	1991-05-28
IL86820A (en)	1991-07-18
GB2206115A (en)	1988-12-29
FI88302C (fi)	1993-04-26
FI883008A0 (fi)	1988-06-22
DK340188D0 (da)	1988-06-21
GR1002318B (el)	1996-05-13
ZA884505B (en)	1990-02-28
JPS6422876A (en)	1989-01-25
IL86820A0 (en)	1988-11-30

Legal Events

Date	Code	Title	Description
1994-10-10	B1	Patent granted (law 1993)
2001-03-05	PBP	Patent lapsed

Publication	Publication Date	Title
US5177112A (en)	1993-01-05	Substituted 2-aminotetralins
AU655075B2 (en)	1994-12-01	N-alkyl-3-phenyl-3-(2-alkylthiophenoxy)propylamines
CS227019B2 (en)	1984-04-16	Method of preparing (-)-n-methyl-3-(2-methylphenyloxy)-3-phenylpropylamine
HU211575A9 (en)	1995-12-28	2-methyl-thieno-benzodiazepine
KR100417506B1 (ko)	2004-02-05	항우울 치료를 위한 5ｈｔ1 길항제
ES2204154T3 (es)	2004-04-16	Ligandos del receptor 5-ht-1 azabiciclicos.
CA2599872A1 (en)	2006-09-14	Novel salt of quinuclidine derivative
US5256661A (en)	1993-10-26	Substituted 2-aminotetralins and pharmaceutical use
AU615657B2 (en)	1991-10-10	N-{(5R,8S,10R)-2,6-dimethyl-ergoline-8-yl}-2-ethyl-2-methyl- butan-amide, its preparation and pharmaceutical compositions containing it
JPS6335547A (ja)	1988-02-16	置換２−アミノテトラリンおよびその製造方法
CS204036B2 (en)	1981-03-31	Method of producing novel 4-phenyl-thieno/2,3-c/piperid
FI94860B (fi)	1995-07-31	Menetelmä terapeuttisesti käyttökelpoisen (+)-1-/(3,4,5-trimetoksi)bentsyylioksimetyyli/-1-fenyyli-N,N-dimetyyli-n-propyyliamiinin valmistamiseksi
PT86424B (pt)	1990-11-20	Processo para a preparacao de tetra-hidropirido-indoles substituidos
KR100222238B1 (ko)	1999-10-01	스피로 교상 및 비교상 헤테로고리 화합물
FI89796B (fi)	1993-08-13	Oxisalicylamidoderivaters mellanprodukter
CS216651B2 (en)	1982-11-26	Method of making the p-chloracetophenonoxine derivatives
NZ214066A (en)	1988-04-29	3-amino-2,3-dihydro-1-benzoxepine derivatives and pharmaceutical compositions
PL157529B1 (en)	1992-06-30	Method for manufacturing 8 alfa-acyloaminergoline
MXPA01006669A (en)	2002-03-26	5ht1 antagonists for antidepressant therapy
CS266312B2 (cs)	1989-12-13	Způsob výroby benzamidových derivátů