DK171782B1 - Anvendelse af 3,4-dihydro-2H-benzo[b]pyraner til fremstilling af et lægemiddel imod obstruktive funktionsforstyrrelser af lungerne - Google Patents

Anvendelse af 3,4-dihydro-2H-benzo[b]pyraner til fremstilling af et lægemiddel imod obstruktive funktionsforstyrrelser af lungerne Download PDF

Info

Publication number: DK171782B1
Authority: DK; Denmark
Prior art keywords: formula; dihydro; benzo; compounds; dimethyl
Prior art date: 1988-07-19

Application number

DK355489A

Other languages

Danish (da)

English (en)

Other versions

DK355489D0 (da

DK355489A (da

Inventor

Heinrich Christian Englert

Erik Klaus

Dieter Mania

Bernward Schoelkens

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-07-19

Filing date

1989-07-18

Publication date

1997-05-26

1989-07-18 Application filed by Hoechst Ag filed Critical Hoechst Ag

1989-07-18 Publication of DK355489D0 publication Critical patent/DK355489D0/da

1990-01-20 Publication of DK355489A publication Critical patent/DK355489A/da

1997-05-26 Application granted granted Critical

1997-05-26 Publication of DK171782B1 publication Critical patent/DK171782B1/da

Links

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LJZPPWWHKPGCHS-UHFFFAOYSA-N propargyl chloride Chemical class ClCC#C LJZPPWWHKPGCHS-UHFFFAOYSA-N 0.000 description 1
239000003380 propellant Substances 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
230000036387 respiratory rate Effects 0.000 description 1
229960002052 salbutamol Drugs 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000000926 separation method Methods 0.000 description 1
230000016160 smooth muscle contraction Effects 0.000 description 1
QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
239000007921 spray Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000008107 starch Substances 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
125000001424 substituent group Chemical group 0.000 description 1
235000000346 sugar Nutrition 0.000 description 1
239000002600 sunflower oil Substances 0.000 description 1
239000002511 suppository base Substances 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
239000003826 tablet Substances 0.000 description 1
YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
RWRDLPDLKQPQOW-UHFFFAOYSA-N tetrahydropyrrole Substances C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 description 1
229960000278 theophylline Drugs 0.000 description 1
210000001635 urinary tract Anatomy 0.000 description 1
210000004291 uterus Anatomy 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
235000013311 vegetables Nutrition 0.000 description 1
238000005303 weighing Methods 0.000 description 1
238000010626 work up procedure Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Pyrane Compounds (AREA)

DK355489A 1988-07-19 1989-07-18 Anvendelse af 3,4-dihydro-2H-benzo[b]pyraner til fremstilling af et lægemiddel imod obstruktive funktionsforstyrrelser af lungerne DK171782B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3824446A DE3824446A1 (de)	1988-07-19	1988-07-19	Verwendung substituierter 3,4-dihydro-2h-benzopyrane als heilmittel gegen obstruktive funktionsstoerungen der lunge und/oder stoerungen der ableitenden harnwege
DE3824446		1988-07-19

Publications (3)

Publication Number	Publication Date
DK355489D0 DK355489D0 (da)	1989-07-18
DK355489A DK355489A (da)	1990-01-20
DK171782B1 true DK171782B1 (da)	1997-05-26

Family

ID=6359009

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK355489A DK171782B1 (da)	1988-07-19	1989-07-18	Anvendelse af 3,4-dihydro-2H-benzo[b]pyraner til fremstilling af et lægemiddel imod obstruktive funktionsforstyrrelser af lungerne

Country Status (18)

Country	Link
EP (2)	EP0351720B1 (cs)
JP (1)	JPH0273015A (cs)
KR (1)	KR900001367A (cs)
AT (1)	ATE110270T1 (cs)
AU (1)	AU621388B2 (cs)
CA (1)	CA1336891C (cs)
CZ (1)	CZ417091A3 (cs)
DE (2)	DE3824446A1 (cs)
DK (1)	DK171782B1 (cs)
ES (1)	ES2061816T3 (cs)
FI (1)	FI893460A7 (cs)
HU (1)	HU210149B (cs)
IE (1)	IE63872B1 (cs)
IL (1)	IL91015A (cs)
NZ (1)	NZ229961A (cs)
PH (1)	PH26696A (cs)
PT (1)	PT91197B (cs)
ZA (1)	ZA895459B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW244350B (cs) *	1991-12-14	1995-04-01	Hoechst Ag
TW316850B (cs) *	1992-02-28	1997-10-01	Takeda Pharm Industry Co Ltd
HUT72741A (en) *	1992-12-19	1996-05-28	Alkaloida Vegyeszeti Gyar	Method for producing benzopyrane derivatives and pharmaceutical compositions containing them
GB9316111D0 (en) *	1993-08-04	1993-09-22	Pfizer Ltd	Benzopyrans
AU2273301A (en)	1999-12-23	2001-07-09	Robert E. Coifman	Methods and formulations for the efficient delivery of water-insoluble drugs by nebulizer
KR100475147B1 (ko) *	2002-09-09	2005-03-10	정의상	알루미나 분진 중의 유해가스 제거를 위한 탈취제 조성물
ATE407724T1 (de)	2002-11-12	2008-09-15	Warner Lambert Co	Methode zur stimulierung von haarwuchs auf der basis von benzopyranen

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3364734D1 (en) *	1982-10-19	1986-08-28	Beecham Group Plc	Novel chromans and chromenes
GB8419515D0 (en) *	1984-07-31	1984-09-05	Beecham Group Plc	Treatment
GB8513369D0 (en) *	1985-05-28	1985-07-03	Beecham Group Plc	Treatment
DE3703227A1 (de) *	1987-02-04	1988-08-18	Hoechst Ag	Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
ES2058148T3 (es) *	1987-02-04	1994-11-01	Hoechst Ag	N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.

1988
- 1988-07-19 DE DE3824446A patent/DE3824446A1/de not_active Withdrawn
1989
- 1989-07-14 EP EP89112897A patent/EP0351720B1/de not_active Expired - Lifetime
- 1989-07-14 AT AT89112897T patent/ATE110270T1/de not_active IP Right Cessation
- 1989-07-14 DE DE58908228T patent/DE58908228D1/de not_active Expired - Fee Related
- 1989-07-14 ES ES89112897T patent/ES2061816T3/es not_active Expired - Lifetime
- 1989-07-17 FI FI893460A patent/FI893460A7/fi not_active IP Right Cessation
- 1989-07-17 HU HU893591A patent/HU210149B/hu not_active IP Right Cessation
- 1989-07-17 EP EP93105146A patent/EP0560399A1/de not_active Withdrawn
- 1989-07-17 PH PH38951A patent/PH26696A/en unknown
- 1989-07-17 NZ NZ229961A patent/NZ229961A/xx unknown
- 1989-07-18 ZA ZA895459A patent/ZA895459B/xx unknown
- 1989-07-18 IE IE232389A patent/IE63872B1/en not_active IP Right Cessation
- 1989-07-18 KR KR1019890010129A patent/KR900001367A/ko not_active Ceased
- 1989-07-18 AU AU38189/89A patent/AU621388B2/en not_active Ceased
- 1989-07-18 IL IL9101589A patent/IL91015A/en not_active IP Right Cessation
- 1989-07-18 PT PT91197A patent/PT91197B/pt not_active IP Right Cessation
- 1989-07-18 DK DK355489A patent/DK171782B1/da not_active IP Right Cessation
- 1989-07-18 JP JP1183848A patent/JPH0273015A/ja active Pending
- 1989-07-18 CA CA000605990A patent/CA1336891C/en not_active Expired - Fee Related
1991
- 1991-12-30 CZ CS914170A patent/CZ417091A3/cs unknown

Also Published As

Publication number	Publication date
NZ229961A (en)	1991-11-26
EP0351720A2 (de)	1990-01-24
AU3818989A (en)	1990-01-25
EP0560399A1 (de)	1993-09-15
FI893460A0 (fi)	1989-07-17
ATE110270T1 (de)	1994-09-15
EP0351720A3 (de)	1992-01-02
JPH0273015A (ja)	1990-03-13
CZ417091A3 (en)	1993-02-17
IE63872B1 (en)	1995-06-14
KR900001367A (ko)	1990-02-27
IL91015A (en)	1994-11-28
FI893460A7 (fi)	1990-01-20
DE3824446A1 (de)	1990-01-25
AU621388B2 (en)	1992-03-12
EP0351720B1 (de)	1994-08-24
CA1336891C (en)	1995-09-05
ZA895459B (en)	1990-03-28
PT91197B (pt)	1995-07-18
DK355489D0 (da)	1989-07-18
ES2061816T3 (es)	1994-12-16
PT91197A (pt)	1990-02-08
DK355489A (da)	1990-01-20
HU210149B (en)	1995-02-28
DE58908228D1 (de)	1994-09-29
HUT55988A (en)	1991-07-29
IE892323L (en)	1990-01-19
PH26696A (en)	1992-09-15

Legal Events

Date	Code	Title	Description
2003-03-03	PBP	Patent lapsed	Country of ref document: DK

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US5250547A (en)	1993-10-05	Benzopyran derivatives
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JPH03145464A (ja)	1991-06-20	光学活性１，４―ジヒドロピリジン誘導体
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JPH0699308B2 (ja)	1994-12-07	ヒダントイン誘導体を有効成分とする循環器系疾患の予防及び治療剤並びに循環器系疾患と糖尿病合併症の同時的予防及び治療剤
JP2000515118A (ja)	2000-11-14	置換６ｈ―１，３，４―チアジアジン―２―アミン、麻酔剤、心臓血管剤および代謝低下剤としてのそれらの使用、およびそれらを含有する医薬組成物
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