DK172440B1 - Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til - Google Patents

Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til Download PDF

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Publication number
DK172440B1
DK172440B1 DK198900022A DK2289A DK172440B1 DK 172440 B1 DK172440 B1 DK 172440B1 DK 198900022 A DK198900022 A DK 198900022A DK 2289 A DK2289 A DK 2289A DK 172440 B1 DK172440 B1 DK 172440B1
Authority
DK
Denmark
Prior art keywords
cea
monoclonal antibody
derivatives
antibodies
antibody
Prior art date
Application number
DK198900022A
Other languages
Danish (da)
English (en)
Other versions
DK2289D0 (da
DK2289A (da
Inventor
Jean-Pierre Mach
Franz Buchegger
Original Assignee
Res Corp Technologies Inc
Franz Buchegger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Corp Technologies Inc, Franz Buchegger filed Critical Res Corp Technologies Inc
Publication of DK2289D0 publication Critical patent/DK2289D0/da
Publication of DK2289A publication Critical patent/DK2289A/da
Application granted granted Critical
Publication of DK172440B1 publication Critical patent/DK172440B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198900022A 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til DK172440B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8800078 1988-01-05
GB888800078A GB8800078D0 (en) 1988-01-05 1988-01-05 Novel antibodies

Publications (3)

Publication Number Publication Date
DK2289D0 DK2289D0 (da) 1989-01-04
DK2289A DK2289A (da) 1989-07-06
DK172440B1 true DK172440B1 (da) 1998-07-27

Family

ID=10629465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900022A DK172440B1 (da) 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til

Country Status (12)

Country Link
US (1) US5047507A (fr)
EP (1) EP0323805B1 (fr)
JP (1) JPH025893A (fr)
AT (1) ATE101202T1 (fr)
AU (1) AU619232B2 (fr)
CA (1) CA1315219C (fr)
DE (1) DE3887675T2 (fr)
DK (1) DK172440B1 (fr)
ES (1) ES2061730T3 (fr)
GB (1) GB8800078D0 (fr)
IE (1) IE62439B1 (fr)
PT (1) PT89385B (fr)

Families Citing this family (47)

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AU618317B2 (en) * 1987-12-31 1991-12-19 Tanox Biosystems, Inc. Unique antigenic epitopes on ige-bearing b lymphocytes
US5843708A (en) * 1988-01-05 1998-12-01 Ciba-Geigy Corporation Chimeric antibodies
GB8800077D0 (en) * 1988-01-05 1988-02-10 Ciba Geigy Ag Novel chimeric antibodies
EP0457875A4 (en) * 1989-11-13 1993-03-03 Xoma Corporation Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
JPH07506484A (ja) * 1992-01-29 1995-07-20 サイ−クロン，インコーポレーテッド カルチノーマ関連抗原（ｓｋ１），ｓｋ１に対するモノクローナル抗体，これら抗体を産生する方法及びその使用
WO1993016193A1 (fr) * 1992-02-14 1993-08-19 Suntory Limited Anticorps inhibant l'adhesion cellulaire et inhibiteur d'adhesion cellulaire le contenant
EP0584343B1 (fr) * 1992-03-10 1999-01-20 La Jolla Cancer Research Foundation Phosphatase alcaline intestinale recombinee du veau
US5502037A (en) * 1993-07-09 1996-03-26 Neuromed Technologies, Inc. Pro-cytotoxic drug conjugates for anticancer therapy
US5874540A (en) 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
ATE223060T1 (de) * 1994-11-28 2002-09-15 Abbott Lab Stabile wässrige steroid-standardproben für immuntests
US5648268A (en) * 1994-12-06 1997-07-15 Ibm Corporation Radionuclide exchange detection of ultra trace ionic impurities in water
US6207805B1 (en) 1997-07-18 2001-03-27 University Of Iowa Research Foundation Prostate cell surface antigen-specific antibodies
US6682940B2 (en) * 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6828157B1 (en) 1999-05-04 2004-12-07 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
US20020139628A1 (en) * 2001-03-30 2002-10-03 Wen-Chen Chang Retractable handle assembly
AU2003249366A1 (en) * 2002-06-24 2004-01-06 Tufts University Silk biomaterials and methods of use thereof
CN101972478B (zh) 2002-10-08 2012-10-31 免疫医疗公司 抗体治疗
WO2004062697A2 (fr) 2003-01-07 2004-07-29 Tufts University Matières de fibroïne de soie et utilisation de celles-ci
EP1613796B1 (fr) * 2003-04-10 2017-03-22 Tufts University Solution aqueuse concentree de fibroine et utilisation
WO2005000483A1 (fr) * 2003-06-06 2005-01-06 Tufts University Procede de formation d'enrobages inorganiques
JP2006214765A (ja) * 2005-02-01 2006-08-17 Bml Inc ヒトＡｐｏＡ−Ｖ蛋白質に対する抗体、及び、当該抗体を用いたヒトＡｐｏＡ−Ｖ蛋白質定量測定系
US9102916B2 (en) * 2007-02-27 2015-08-11 Trustees Of Tufts College Tissue-engineered silk organs
US8187616B2 (en) 2007-05-29 2012-05-29 Trustees Of Tufts College Method for silk fibroin gelation using sonication
WO2009100280A2 (fr) * 2008-02-07 2009-08-13 Trustees Of Tufts College Compositions d'hydroxyapatite et de soie en trois dimensions
WO2009140588A1 (fr) * 2008-05-15 2009-11-19 Trustees Of Tufts College Libération d'adénosine à base de polymère de soie : potentiel thérapeutique pour l'épilepsie
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
JP5896743B2 (ja) * 2008-10-09 2016-03-30 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ グリセロールを含有する改変された絹フィルム
EP2453931A4 (fr) 2009-07-14 2014-04-30 Tufts College Systèmes de matériau de soie électrofilée pour cicatrisation
EP2483460B1 (fr) 2009-09-28 2015-09-02 Trustees Of Tufts College Procédé de préparation de fibres de soie électrogélifiées étirées
IN2012DN02358A (fr) 2009-09-29 2015-08-21 Tufts College
WO2011109691A2 (fr) 2010-03-05 2011-09-09 Trustees Of Tufts College Compositions ionomères à base de soie
US9566365B2 (en) 2010-09-01 2017-02-14 Trustees Of Tufts College Silk fibroin and polyethylene glycol-based biomaterials
EP3495015B1 (fr) 2010-10-19 2022-12-07 Trustees Of Tufts College Micro-aiguilles à base de fibroïne de soie et leurs procédés de fabrication
RU2578468C2 (ru) 2010-12-16 2016-03-27 Дженентек, Инк. Способы диагностики и лечения, связанные с ингибированием th2
WO2012145652A1 (fr) 2011-04-20 2012-10-26 Trustees Of Tufts College Revêtements de soie dynamiques pour dispositifs implantables
EP3884931A3 (fr) 2012-02-06 2021-12-01 Children's Medical Center, Corp. Biomatériau multicouche pour la régénération tissulaire et la cicatrisation de plaies
MX338711B (es) 2012-10-12 2016-04-28 Medimmune Ltd Pirrolobenzodiazepinas y conjugados de las mismas.
MX362970B (es) 2013-03-13 2019-02-28 Medimmune Ltd Pirrolobenzodiazepinas y conjugados de las mismas.
EP3193940A1 (fr) 2014-09-10 2017-07-26 Medimmune Limited Pyrrolobenzodiazépines et leurs conjugués
EP3525829A1 (fr) 2016-10-11 2019-08-21 Medimmune Limited Conjugués anticorps-médicament associés à des agents thérapeutiques à médiation immunitaire
CA3098103A1 (fr) 2018-05-23 2019-11-28 Adc Therapeutics Sa Adjuvant moleculaire
US20230372528A1 (en) 2020-10-16 2023-11-23 University Of Georgia Research Foundation, Inc. Glycoconjugates
GB202102396D0 (en) 2021-02-19 2021-04-07 Adc Therapeutics Sa Molecular adjuvant
EP4426727A2 (fr) 2021-11-03 2024-09-11 Hangzhou Dac Biotech Co., Ltd. Conjugaison spécifique d'un anticorps

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361544A (en) * 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
JPH0811075B2 (ja) * 1982-06-30 1996-02-07 雄治 松岡 単クローン性抗ｃｅａ抗体
WO1984002983A1 (fr) * 1983-01-21 1984-08-02 Frederick James Primus Antigenes specifiques de la famille cea (antigene carcino-embryonaire), anticorps specifiques de ces antigenes et leurs procedes d'utilisation
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung

Also Published As

Publication number Publication date
EP0323805B1 (fr) 1994-02-02
AU619232B2 (en) 1992-01-23
EP0323805A3 (en) 1990-04-25
ATE101202T1 (de) 1994-02-15
AU2739188A (en) 1989-07-06
DK2289D0 (da) 1989-01-04
CA1315219C (fr) 1993-03-30
PT89385A (pt) 1990-02-08
US5047507A (en) 1991-09-10
GB8800078D0 (en) 1988-02-10
DK2289A (da) 1989-07-06
PT89385B (pt) 1993-09-30
ES2061730T3 (es) 1994-12-16
IE62439B1 (en) 1995-02-08
EP0323805A2 (fr) 1989-07-12
JPH025893A (ja) 1990-01-10
DE3887675T2 (de) 1994-06-30
IE890018L (en) 1989-07-05
DE3887675D1 (de) 1994-03-17

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed