DK18984A - 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer - Google Patents

1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer Download PDF

Info

Publication number
DK18984A
DK18984A DK18984A DK18984A DK18984A DK 18984 A DK18984 A DK 18984A DK 18984 A DK18984 A DK 18984A DK 18984 A DK18984 A DK 18984A DK 18984 A DK18984 A DK 18984A
Authority
DK
Denmark
Prior art keywords
pyrrolo
pyrrole
dihydro
carboxylic acids
vinyl
Prior art date
Application number
DK18984A
Other languages
Danish (da)
English (en)
Other versions
DK18984D0 (da
Inventor
Joseph M Muchowski
Stefan H Unger
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK18984D0 publication Critical patent/DK18984D0/da
Publication of DK18984A publication Critical patent/DK18984A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK18984A 1983-01-17 1984-01-16 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer DK18984A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/458,243 US4560699A (en) 1983-01-17 1983-01-17 5-(4-Vinylbenzoyl)-1,2-dihydro-3H-pyrrolo-[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof and use as analgesics and anti-inflammatories
US45824383 1983-01-17

Publications (2)

Publication Number Publication Date
DK18984D0 DK18984D0 (da) 1984-01-16
DK18984A true DK18984A (da) 1984-07-18

Family

ID=23819967

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18984A DK18984A (da) 1983-01-17 1984-01-16 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer

Country Status (15)

Country Link
US (1) US4560699A (de)
EP (1) EP0114632B1 (de)
JP (1) JPS59137483A (de)
KR (1) KR840007413A (de)
AT (1) ATE29721T1 (de)
AU (1) AU558271B2 (de)
CA (1) CA1229088A (de)
DE (1) DE3466219D1 (de)
DK (1) DK18984A (de)
FI (1) FI78698C (de)
HU (1) HU190543B (de)
IL (1) IL70691A (de)
NO (1) NO161675C (de)
NZ (1) NZ206839A (de)
ZA (1) ZA84326B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4849526A (en) * 1987-01-14 1989-07-18 Syntex (U.S.A.) Inc. Process for preparing (±)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4874872A (en) * 1987-01-14 1989-10-17 Syntex (U.S.A.) Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
HU198927B (en) * 1987-01-14 1989-12-28 Richter Gedeon Vegyeszet Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4835288A (en) * 1987-01-14 1989-05-30 Syntex Inc. Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE4338770A1 (de) * 1993-11-12 1995-05-18 Matthias Dr Lehr Indol-2-alkansäuren und ihre Derivate als Hemmstoffe der Phospholipase A¶2¶
KR0140134B1 (ko) * 1994-11-16 1998-06-01 강재헌 피롤리진 유도체의 제조방법
ES2449194T3 (es) * 2000-01-19 2014-03-18 Cadila Healthcare Limited Compuestos que tienen actividades hipolipidémica e hipocolesterolémica, procedimiento para su preparación y composiciones farmacéuticas que los contienen
DE10004157A1 (de) 2000-02-01 2001-08-02 Merckle Gmbh Chem Pharm Fabrik 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
JPS584711B2 (ja) * 1978-08-02 1983-01-27 参天製薬株式会社 ピロリジン誘導体
US4347186A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
US4347185A (en) * 1980-10-20 1982-08-31 Syntex (U.S.A.) Inc. Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4612325A (en) * 1982-06-08 1986-09-16 Syntex (U.S.A) Inc. 5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories

Also Published As

Publication number Publication date
FI840153L (fi) 1984-07-18
ZA84326B (en) 1985-09-25
AU2351884A (en) 1984-07-19
DE3466219D1 (en) 1987-10-22
NO161675C (no) 1989-09-13
IL70691A (en) 1986-08-31
ATE29721T1 (de) 1987-10-15
AU558271B2 (en) 1987-01-22
EP0114632B1 (de) 1987-09-16
CA1229088A (en) 1987-11-10
EP0114632A1 (de) 1984-08-01
JPS59137483A (ja) 1984-08-07
FI78698B (fi) 1989-05-31
KR840007413A (ko) 1984-12-07
NO840145L (no) 1984-07-18
FI840153A0 (fi) 1984-01-16
HU190543B (en) 1986-09-29
IL70691A0 (en) 1984-04-30
US4560699A (en) 1985-12-24
NO161675B (no) 1989-06-05
NZ206839A (en) 1987-09-30
DK18984D0 (da) 1984-01-16
FI78698C (fi) 1989-09-11

Similar Documents

Publication Publication Date Title
RU2217431C2 (ru) Тиенопиримидины, способ их получения, фармацевтическая композиция, обладающая действием ингибиторов фосфодиэстеразы v
DK18984A (da) 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer
DE3369972D1 (en) Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids, their preparation and use
KR930000514A (ko) 7-아자이소인돌리닐-퀴놀론- 및 -나프티리돈카르복실산 유도체
ATE36517T1 (de) Optisch aktive alpha-substituierte arylketone, verfahren zu ihrer herstellung und ihre anwendung in der herstellung von alphaarylalkancarbons|uren.
YU43235B (en) Process for preparing 6-chloro-or 6-bromo-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylic acid and alkyl esthers thereoff
DE3165209D1 (en) 2-substituted-4-hydroxy-3-quinolinecarboxylic acids, their preparation, their use as medicaments, compositions containing them and intermediates
SE7903976L (sv) Nya purinderivat anvendbara sasom icke-adrenenergiska bronkodilatorer
YU45810B (sh) Postupak za dobijanje hinolin karboksilnih kiselina
JPS57109754A (en) N-benzoyl-omega-anilinoalkane carboxylic acid compound
JPS5758668A (en) Manufacture of quinoline, naphthyridine and other nitrogen-bi-heterocyclic compound
ATE29141T1 (de) Epoxidharz-diammoniumsalz-emulsion und verfahren zu ihrer herstellung.
ATE15040T1 (de) Verbessertes verfahren zur herstellung von 1hpyrrol-2-essigsaeureestern.
JPS5289695A (en) Novel 7alpha-methoxycephalosporins and preparation thereof
GR80358B (en) Substituted pyrido (1,2-c) imidazo (1,2-a) benzimidazole, method for the preparation thereof, the use thereof, pharmaceutical preparations based on said compounds
ES8704971A1 (es) Procedimiento para preparar triesteres de acido corticosteroidefosforico
SE7710933L (sv) 5-alkoxi-pikolinsyror
YU42307B (en) Process for preparing imidazo (1,2-a)imidazoles
FI803887L (fi) Nya substituerade 2-fenylamino-imidazoliner-(2) deras syraadditionssalter dessa innehaollande laekemedel och deras framstaellningsfoerfarande
FI803969L (fi) Nya substituerade 2-fenylamino-imidazoliner-(2) deras syraadditionssalter dessa innehaollande laekemedel och foerfarande foer deras framstaellning
IE42992L (en) PYRIMIDO [1,2-a] QUINOLINE DERIVATIVES
SE7707418L (sv) Nya svavelhaltiga n-bensylaminosyror och forfarande for framstellning derav
JPS6432254A (en) Recording material
JPS5474845A (en) Halogen-containing resin composition having improved processability
JPS5373566A (en) 7,8,9,10,-tetrahydrophenanthridone-3-acetic acids

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment