DK189982A - Oligosaccharider med korte kaeder der har biologiske egenskaber deres fremstilling og deres anvendelse som laegemidler - Google Patents

Oligosaccharider med korte kaeder der har biologiske egenskaber deres fremstilling og deres anvendelse som laegemidler Download PDF

Info

Publication number
DK189982A
DK189982A DK189982A DK189982A DK189982A DK 189982 A DK189982 A DK 189982A DK 189982 A DK189982 A DK 189982A DK 189982 A DK189982 A DK 189982A DK 189982 A DK189982 A DK 189982A
Authority
DK
Denmark
Prior art keywords
octasaccharides
abreviation
preparation
see diagramm
denoted below
Prior art date
Application number
DK189982A
Other languages
English (en)
Inventor
J C Lormeau
J Choay
M Petitou
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Choay Sa filed Critical Choay Sa
Publication of DK189982A publication Critical patent/DK189982A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/02—Carbon-oxygen lyases (4.2) acting on polysaccharides (4.2.2)
    • C12Y402/02007—Heparin lyase (4.2.2.7), i.e. heparinase I

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
DK189982A 1981-04-29 1982-04-28 Oligosaccharider med korte kaeder der har biologiske egenskaber deres fremstilling og deres anvendelse som laegemidler DK189982A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8108604A FR2504928A1 (fr) 1981-04-29 1981-04-29 Oligosaccharides a chaines courtes possedant des proprietes biologiques, leur preparation et leurs applications en tant que medicaments

Publications (1)

Publication Number Publication Date
DK189982A true DK189982A (da) 1982-10-30

Family

ID=9257922

Family Applications (1)

Application Number Title Priority Date Filing Date
DK189982A DK189982A (da) 1981-04-29 1982-04-28 Oligosaccharider med korte kaeder der har biologiske egenskaber deres fremstilling og deres anvendelse som laegemidler

Country Status (9)

Country Link
EP (1) EP0064452B1 (da)
JP (1) JPS57190001A (da)
AT (1) ATE12791T1 (da)
CA (1) CA1180292A (da)
DE (1) DE3263083D1 (da)
DK (1) DK189982A (da)
ES (1) ES8302094A1 (da)
FR (1) FR2504928A1 (da)
IE (1) IE52906B1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0209924A1 (en) * 1985-07-12 1987-01-28 Akzo N.V. New anti-trombosis agent based on glycosaminoglycan, process for its preparation, and pharmaceutical compositions
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
US5106734A (en) * 1986-04-30 1992-04-21 Novo Nordisk A/S Process of using light absorption to control enzymatic depolymerization of heparin to produce low molecular weight heparin
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
EP0861903A1 (en) * 1997-02-22 1998-09-02 Lansing, Manfred Method for reversible immobilizing oligo and/or polysaccharides
US5985582A (en) * 1997-12-09 1999-11-16 Sigma-Aldrich Co. Thrombin-based assay for antithrombin III
FR2845686B1 (fr) * 2002-10-10 2013-08-30 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
FR2857971B1 (fr) * 2003-07-24 2005-08-26 Aventis Pharma Sa Melanges d'oligosaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
EP1582531A1 (en) 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
EP1792621B1 (en) 2005-11-30 2012-04-04 Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni" Orally administrable heparin derivatives
EP2279249A4 (en) 2008-05-30 2014-03-05 Momenta Pharmaceuticals Inc Saccharide structures and process for their preparation and use
US20190002596A1 (en) * 2015-12-30 2019-01-03 Shenzhen Hepalink Pharmaceutical Group Co., Ltd. Sulfated heparin oligosaccharide and preparation method and application thereof
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
CA3144968A1 (en) 2019-07-09 2021-01-14 Optimvia Llc Methods for synthesizing anticoagulant polysaccharides
JP7611465B2 (ja) * 2019-10-10 2025-01-10 ジェイ・アイ・サイエンス有限会社 溶離液性の利用フラクションコレクター

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766167A (en) * 1971-03-26 1973-10-16 Research Corp Orally active anticoagulant
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
JPH0231721A (ja) * 1988-07-20 1990-02-01 Matsushita Electric Ind Co Ltd 充電式掃除機

Also Published As

Publication number Publication date
DE3263083D1 (en) 1985-05-23
ATE12791T1 (de) 1985-05-15
EP0064452A1 (fr) 1982-11-10
CA1180292A (en) 1985-01-02
FR2504928A1 (fr) 1982-11-05
JPS57190001A (en) 1982-11-22
ES511470A0 (es) 1983-02-01
ES8302094A1 (es) 1983-02-01
EP0064452B1 (fr) 1985-04-17
IE52906B1 (en) 1988-04-13
FR2504928B1 (da) 1984-02-24
IE820741L (en) 1982-10-29

Similar Documents

Publication Publication Date Title
JPS57190001A (en) Biological short chain oligosaccharide, manufacture and use as drug
US5578590A (en) Pharmaceutical composition preparation for use in inhibiting protein kinase C
TR200000671T2 (tr) FP agonistleri olarak yararlı aromatik C16-C20-ikameli tetrahidro prostaglandinler.
ES2174064T3 (es) Derivados de 1,3 - dihidro - 1 - (fenilalquil) - 2h - imidazol - 2 - ona que presentan una actividad frente a pde iv y a citoquinas.
GB1043489A (en) Imidazo[2,1-b]thiazoles and process for preparing them
TR200000673T2 (tr) FP agonistleri olarak yararlı aromatik C16-C20- ikameli tetrahidro prostaglandinler.
BR9811779A (pt) Tetrahidro prostaglandina s substituìdas por c16-c20 aromáticos úteis como agonistas fp
BR9713465A (pt) Inibidores metalotprotease de amina cìclica sibstituìda
ATE82681T1 (de) 2',3'-dideoxy-3'-fluorothymidin und verwandte verbindungen zur behandlung von adenovirusinfektionen.
NO932120L (no) Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling
BR0008778A (pt) Análogos de prostaglandinas seletivos para fpc16 insaturados
BR0008776A (pt) Análogos de prostaglandinas fp-seletivosinsaturados c16
BR0109328A (pt) Inibidores de metaloprotease n-substituìdos, contendo cadeia lateral heterocìclica
ES2149403T3 (es) Benciloxicarbonilguanidinas sustituidas como inhibidores del intercambiador de protones de sodio, procedimiento para su preparacion, su empleo como medicamento o agente de diagnostico, asi como medicamento que las contiene.
DK1115697T3 (da) Umættede hydroximsyrederivater som PARP-inhibitorer
BR0109617A (pt) Composição farmacêutica, oligossacarìdeo, processo de preparação de oligossacarìdeos, e, utilização de oligossacarìdeos
BR9909268A (pt) C11 oximil e hidroxilamino prostaglandinas úteis como agonistas de fp
ATE7202T1 (de) Nichtadsorbierbare, mukolytische verbindungen, verfahren zu ihrer herstellung und therapeutische zusammensetzungen, die diese verbindungen als wirkstoff enthalten.
BR0014759A (pt) Inibidores de metaloprotease beta dissubstituìdos
DK0561882T3 (da) Hydroxamsyrederivater, som inhiberer lipoxygenase
JPH06248267A (ja) 新規抗酸化剤
DK291786A (da) Neuroleptisk aktivt, farmaceutisk praeparat og fremgangsmaade til dets fremstilling
US4205081A (en) Composition and method for preventing or treating swine dysentery
ES2044534T3 (es) Un metodo para la preparacion de una composicion tromboliticamente activa.
ES2055440T3 (es) Derivados del acido quinurenico, su preparacion y composiciones farmaceuticas que los contienen.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment