DK2007396T3 - Enfumafungin-derivat som antimykotika - Google Patents

Enfumafungin-derivat som antimykotika

Info

Publication number: DK2007396T3
Authority: DK; Denmark
Prior art keywords: antimycotics; enfumafungin derivatives; enfumafungin; derivatives
Prior art date: 2006-04-03

Application number

DK07754382.5T

Other languages

English (en)

Inventor

James M Balkovec

Frances Aileen Bouffard

Bruno Tse

James Dropinski

Dongfang Meng

Mark L Greenlee

Michael Peel

Weiming Fan

Ahmed Mamai

Hao Liu

Keqaing Li

Original Assignee

Merck Sharp & Dohme

Scynexis Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-04-03

Filing date

2007-03-29

Publication date

2013-03-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38357146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2007396(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2007-03-29 Application filed by Merck Sharp & Dohme, Scynexis Inc filed Critical Merck Sharp & Dohme

2013-03-18 Application granted granted Critical

2013-03-18 Publication of DK2007396T3 publication Critical patent/DK2007396T3/da

Links

230000001857 anti-mycotic effect Effects 0.000 title 1
239000002543 antimycotic Substances 0.000 title 1
IAOFPTKYKOAKGZ-CRWQHXLTSA-N enfumafungin Chemical class O([C@H]1[C@H](OC(C)=O)C[C@@]23C(O)OC[C@]1(C)[C@@H]2CC[C@@H]1[C@@]2(C)CC[C@]([C@H]([C@]2(C)CC=C13)C(O)=O)(C)[C@H](C)C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O IAOFPTKYKOAKGZ-CRWQHXLTSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)

DK07754382.5T 2006-04-03 2007-03-29 Enfumafungin-derivat som antimykotika DK2007396T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US78864806P	2006-04-03	2006-04-03
US87220106P	2006-12-01	2006-12-01
PCT/US2007/007856 WO2007127012A1 (en)	2006-04-03	2007-03-29	Antifungal agents

Publications (1)

Publication Number	Publication Date
DK2007396T3 true DK2007396T3 (da)	2013-03-18

Family

ID=38357146

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07754382.5T DK2007396T3 (da)	2006-04-03	2007-03-29	Enfumafungin-derivat som antimykotika

Country Status (12)

Country	Link
US (1)	US7863465B2 (da)
EP (1)	EP2007396B1 (da)
JP (1)	JP5245057B2 (da)
CN (1)	CN101454010B (da)
AU (1)	AU2007245024B2 (da)
CA (1)	CA2649432C (da)
CL (1)	CL2007000918A1 (da)
DK (1)	DK2007396T3 (da)
ES (1)	ES2402659T3 (da)
PE (1)	PE20080131A1 (da)
TW (1)	TW200811194A (da)
WO (2)	WO2007127012A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN101861150B (zh) *	2007-09-28	2014-07-16	默克夏普和道赫莫公司	抗真菌制剂
EA018337B1 (ru) *	2008-08-12	2013-07-30	Мерк Шарп Энд Дом Корп.	Противогрибковые средства
CN104877001B (zh) *	2008-08-12	2020-07-03	西尼克斯公司	抗真菌制剂
CN102176828B (zh) *	2008-08-12	2015-11-25	西尼克斯公司	抗真菌制剂
WO2011028654A1 (en)	2009-09-03	2011-03-10	Merck Sharp & Dohme Corp.	Processes for isolation and purification of enfumafungin
US9388126B2 (en)	2012-07-19	2016-07-12	Drexel University	Sigma receptor ligands and methods of modulating cellular protein homeostasis using same
EA201992413A1 (ru) *	2017-04-10	2020-03-16	Сайнексис, Инк.	Противогрибковые средства, используемые в комбинации
KR102807716B1 (ko)	2017-08-04	2025-05-13	싸이넥시스, 인크.	산성 pH에서 증진된 활성을 갖는 항진균제
WO2019089902A1 (en)	2017-11-01	2019-05-09	Drexel University	Compounds, compositions, and methods for treating diseases
IL318793A (en)	2018-01-02	2025-04-01	Scynexis Inc	Injectable compositions of antifungal triterpenoids encapsulated in liposomes
JP7562542B2 (ja)	2019-01-30	2024-10-07	サイネクシス，インコーポレーテッド	真菌性骨－関節感染症を治療するためのトリテルペノイド系抗真菌薬
EP3930716B1 (en)	2019-02-27	2025-09-10	Scynexis, Inc.	Triterpenoid antifungals for the treatment of pneumocystis spp. pneumonia
IL288165B2 (en)	2019-05-16	2026-05-01	Scynexis Inc	Antifungal agents for decolonization of Candida auris
WO2025147685A1 (en)	2024-01-05	2025-07-10	Scynexis, Inc.	Triterpenoid antifungals for use in the treatment of mucormycosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5756472A (en) *	1996-01-31	1998-05-26	Merck & Co., Inc.	Antifungal agent obtained from hormonema
CA2244142C (en)	1996-01-31	2005-03-29	Merck & Co., Inc.	Antifungal compound from hormonema sp.

2007
- 2007-03-29 WO PCT/US2007/007856 patent/WO2007127012A1/en not_active Ceased
- 2007-03-29 ES ES07754382T patent/ES2402659T3/es active Active
- 2007-03-29 DK DK07754382.5T patent/DK2007396T3/da active
- 2007-03-29 CN CN200780019497XA patent/CN101454010B/zh active Active
- 2007-03-29 WO PCT/US2007/007697 patent/WO2007126900A2/en not_active Ceased
- 2007-03-29 JP JP2009504212A patent/JP5245057B2/ja active Active
- 2007-03-29 US US11/727,927 patent/US7863465B2/en active Active
- 2007-03-29 CA CA2649432A patent/CA2649432C/en active Active
- 2007-03-29 EP EP07754382A patent/EP2007396B1/en active Active
- 2007-03-29 AU AU2007245024A patent/AU2007245024B2/en active Active
- 2007-04-02 PE PE2007000397A patent/PE20080131A1/es not_active Application Discontinuation
- 2007-04-02 CL CL200700918A patent/CL2007000918A1/es unknown
- 2007-04-03 TW TW096111918A patent/TW200811194A/zh unknown

Also Published As

Publication number	Publication date
TW200811194A (en)	2008-03-01
WO2007127012B1 (en)	2008-02-21
AU2007245024B2 (en)	2012-09-06
EP2007396B1 (en)	2013-02-13
CN101454010A (zh)	2009-06-10
US20080009504A1 (en)	2008-01-10
WO2007126900A2 (en)	2007-11-08
WO2007126900A3 (en)	2008-01-03
WO2007127012A1 (en)	2007-11-08
CL2007000918A1 (es)	2008-02-08
PE20080131A1 (es)	2008-02-25
CN101454010B (zh)	2012-06-20
JP2009532465A (ja)	2009-09-10
CA2649432C (en)	2014-06-03
AU2007245024A1 (en)	2007-11-08
CA2649432A1 (en)	2007-11-08
JP5245057B2 (ja)	2013-07-24
US7863465B2 (en)	2011-01-04
EP2007396A1 (en)	2008-12-31
ES2402659T3 (es)	2013-05-07

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ATE518837T1 (de)	2011-08-15	Indazolamidderivate
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DK2086968T3 (da)	2012-03-19	5-hydroxymethyl-oxazolidin-2-on-derivater
DK2049480T3 (da)	2014-01-20	2-arylindolderivater som mPGES-1-hæmmere
ATE519760T1 (de)	2011-08-15	Isoxazolimidazolderivate
ATE492529T1 (de)	2011-01-15	Sulfonamidderivate
ATE467626T1 (de)	2010-05-15	Indol-2-yl-piperazin-1-yl-methanon-derivate
DK2167469T3 (da)	2012-11-12	Sulfonylquinolinderivater
ATE518854T1 (de)	2011-08-15	Arylcarbonsäurecyclohexylamidderivate
ATE473994T1 (de)	2010-07-15	Avermectinderivate
UA14575S (uk)	2007-07-10	Профіль
UA15799S (uk)	2008-02-11	Профіль
UA15795S (uk)	2008-02-11	Профіль