DK2049112T3 - Behandling af infektioner og følgesygdomme deraf med kombinerede, dissocierede glucocorticoid-receptor-agonister og anti-infektionsmidler - Google Patents

Behandling af infektioner og følgesygdomme deraf med kombinerede, dissocierede glucocorticoid-receptor-agonister og anti-infektionsmidler

Info

Publication number: DK2049112T3
Authority: DK; Denmark
Prior art keywords: infections; glucocorticoid receptor; sequelae; treatment; combined
Prior art date: 2006-08-07

Application number

DK07813634.8T

Other languages

English (en)

Inventor

Keith Wayne Ward

Gary Phillips

Raili Kerppola

Zhenze Hu

Original Assignee

Bausch & Lomb

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-08-07

Filing date

2007-08-01

Publication date

2012-04-23

2007-08-01 Application filed by Bausch & Lomb filed Critical Bausch & Lomb

2012-04-23 Application granted granted Critical

2012-04-23 Publication of DK2049112T3 publication Critical patent/DK2049112T3/da

Links

229960005475 antiinfective agent Drugs 0.000 title abstract 2
239000004599 antimicrobial Substances 0.000 title abstract 2
229940124750 glucocorticoid receptor agonist Drugs 0.000 title abstract 2
208000015181 infectious disease Diseases 0.000 title abstract 2
239000000203 mixture Substances 0.000 abstract 2
JFUAWXPBHXKZGA-IBGZPJMESA-N 4-fluoro-2-[(4r)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-(1h-pyrrolo[2,3-c]pyridin-2-ylmethyl)pentan-2-yl]phenol Chemical compound C([C@@](O)(CC=1NC2=CN=CC=C2C=1)C(F)(F)F)C(C)(C)C1=CC(F)=CC=C1O JFUAWXPBHXKZGA-IBGZPJMESA-N 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000003904 antiprotozoal agent Substances 0.000 abstract 1
238000002513 implantation Methods 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

DK07813634.8T 2006-08-07 2007-08-01 Behandling af infektioner og følgesygdomme deraf med kombinerede, dissocierede glucocorticoid-receptor-agonister og anti-infektionsmidler DK2049112T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US83611006P	2006-08-07	2006-08-07
PCT/US2007/074936 WO2008021728A2 (en)	2006-08-07	2007-08-01	Treating infections and sequelae thereof with combined dissociated' glucocorticoid receptor agonists and anti-infective agents

Publications (1)

Publication Number	Publication Date
DK2049112T3 true DK2049112T3 (da)	2012-04-23

Family

ID=38823623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK07813634.8T DK2049112T3 (da)	2006-08-07	2007-08-01	Behandling af infektioner og følgesygdomme deraf med kombinerede, dissocierede glucocorticoid-receptor-agonister og anti-infektionsmidler

Country Status (19)

Country	Link
US (1)	US20080033008A1 (da)
EP (2)	EP2364707B1 (da)
JP (1)	JP2010500363A (da)
KR (1)	KR20090040369A (da)
CN (1)	CN101522196A (da)
AT (1)	ATE549022T1 (da)
AU (1)	AU2007284175A1 (da)
BR (1)	BRPI0714815A2 (da)
CA (1)	CA2660151C (da)
CY (1)	CY1113007T1 (da)
DK (1)	DK2049112T3 (da)
ES (2)	ES2381045T3 (da)
MX (1)	MX2009001334A (da)
PL (1)	PL2049112T3 (da)
PT (1)	PT2049112E (da)
SG (1)	SG174031A1 (da)
SI (1)	SI2049112T1 (da)
TW (1)	TWI343918B (da)
WO (1)	WO2008021728A2 (da)

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EP2393355A4 (en) *	2009-01-23	2012-07-25	Inspire Pharmaceuticals Inc	METHOD FOR TREATING A DRY EYE WITH AZITHROMYCIN
US20100247606A1 (en) *	2009-03-25	2010-09-30	Allergan, Inc.	Intraocular sustained release drug delivery systems and methods for treating ocular conditions
US20110077270A1 (en) *	2009-04-21	2011-03-31	Pfeffer Bruce A	Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure
GR1008168B (el) *	2013-03-14	2014-04-08	"Φαρματεν Α.Β.Ε.Ε.",	Παρεντερικο σκευασμα αντιβακτηριακου παραγοντα φθοριοκινολονης και μεθοδος για την παρασκευη αυτου
CA3123490A1 (en)	2019-01-22	2020-07-30	Akribes Biomedical Gmbh	Selective glucocorticoid receptor modifiers for treating impaired skin wound healing
CN111686239B (zh) *	2019-03-11	2021-12-24	中国科学院微生物研究所	抗真菌化合物的应用
CN115516773A (zh) *	2020-05-08	2022-12-23	瑞典爱立信有限公司	多功能aas接收机
WO2021228349A1 (en)	2020-05-11	2021-11-18	Telefonaktiebolaget Lm Ericsson (Publ)	Efficient prach scheduling
WO2026019875A1 (en) *	2024-07-17	2026-01-22	Jnd Therapeutics, Inc.	Methods and formulations for treatment of liver cancer using trifluridine

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2007
- 2007-08-01 BR BRPI0714815-1A patent/BRPI0714815A2/pt not_active IP Right Cessation
- 2007-08-01 EP EP11169315A patent/EP2364707B1/en not_active Not-in-force
- 2007-08-01 PL PL07813634T patent/PL2049112T3/pl unknown
- 2007-08-01 AU AU2007284175A patent/AU2007284175A1/en not_active Abandoned
- 2007-08-01 SG SG2011055688A patent/SG174031A1/en unknown
- 2007-08-01 AT AT07813634T patent/ATE549022T1/de active
- 2007-08-01 CN CNA2007800366571A patent/CN101522196A/zh active Pending
- 2007-08-01 US US11/832,265 patent/US20080033008A1/en not_active Abandoned
- 2007-08-01 CA CA2660151A patent/CA2660151C/en not_active Expired - Fee Related
- 2007-08-01 DK DK07813634.8T patent/DK2049112T3/da active
- 2007-08-01 ES ES07813634T patent/ES2381045T3/es active Active
- 2007-08-01 EP EP07813634A patent/EP2049112B1/en not_active Not-in-force
- 2007-08-01 WO PCT/US2007/074936 patent/WO2008021728A2/en not_active Ceased
- 2007-08-01 JP JP2009523900A patent/JP2010500363A/ja active Pending
- 2007-08-01 PT PT07813634T patent/PT2049112E/pt unknown
- 2007-08-01 KR KR1020097004767A patent/KR20090040369A/ko not_active Ceased
- 2007-08-01 MX MX2009001334A patent/MX2009001334A/es active IP Right Grant
- 2007-08-01 SI SI200730912T patent/SI2049112T1/sl unknown
- 2007-08-01 ES ES11169315T patent/ES2403512T3/es active Active
- 2007-08-06 TW TW096128888A patent/TWI343918B/zh not_active IP Right Cessation
2012
- 2012-05-25 CY CY20121100476T patent/CY1113007T1/el unknown

Also Published As

Publication number	Publication date
CA2660151A1 (en)	2008-02-21
PL2049112T3 (pl)	2012-07-31
EP2049112A2 (en)	2009-04-22
SG174031A1 (en)	2011-09-29
MX2009001334A (es)	2009-02-13
US20080033008A1 (en)	2008-02-07
ES2403512T3 (es)	2013-05-20
CA2660151C (en)	2012-04-17
KR20090040369A (ko)	2009-04-23
WO2008021728A3 (en)	2008-10-09
JP2010500363A (ja)	2010-01-07
EP2364707A3 (en)	2011-12-28
EP2364707A2 (en)	2011-09-14
HK1131046A1 (en)	2010-01-15
EP2049112B1 (en)	2012-03-14
BRPI0714815A2 (pt)	2013-05-21
TWI343918B (en)	2011-06-21
SI2049112T1 (sl)	2012-05-31
AU2007284175A1 (en)	2008-02-21
WO2008021728A2 (en)	2008-02-21
CN101522196A (zh)	2009-09-02
TW200815410A (en)	2008-04-01
PT2049112E (pt)	2012-06-05
ATE549022T1 (de)	2012-03-15
ES2381045T3 (es)	2012-05-22
CY1113007T1 (el)	2016-04-13
EP2364707B1 (en)	2013-04-03

Publication	Publication Date	Title
DK2049112T3 (da)	2012-04-23	Behandling af infektioner og følgesygdomme deraf med kombinerede, dissocierede glucocorticoid-receptor-agonister og anti-infektionsmidler
CL2008002042A1 (es)	2009-01-16	Compuestos derivados de heterociclos nitrogenados enlazados; y su uso en el tratamiento de la diabetes y desordenes metabolicos.
EA200802166A1 (ru)	2009-06-30	Стабильная фармацевтическая композиция с защитным действием от раздражения (варианты), способ ее получения и способ лечения кальций-миметиком с ее помощью
AR051322A1 (es)	2007-01-03	Composiciones de amitraz
EP1787321A4 (en)	2008-12-03	TRAINING OF ULTRASONIC TRANSITIONS THROUGH GASCLUSTER ION RADIATION
ECSP11011412A (es)	2012-03-30	Atropisómeros de derivados de 2-purinil-3-tolil-quinazolinona y métodos de uso
BRPI0813450B8 (pt)	2021-05-25	composto, formulação farmacêutica, e, usos do composto
CL2008002273A1 (es)	2009-07-17	Uso de un compuesto capaz de aumentar el flujo de iones a traves de los canales de potasio kcnq, util para reducir los sintomas de, o para tratar trastornos en los cuales el sistema dopaminergico esta perturbado, como esquizofrenia y otros estados psicoticos.
CL2008001301A1 (es)	2008-12-19	Compuestos derivados de heterociclos de nitrogeno; procedimiento de preparacion; composicion farmaceutica; y uso del compuesto en el tratamiento de una condicion inflamatoria o alergica, tal como una enfermedad inflamatoria u obstructiva de las vias respiratorias mediada por el bloqueo del canal de sodio epitelial.
EA033311B1 (ru)	2019-09-30	Производные бензоксаборола в качестве антибактериальных средств
IL198073A0 (en)	2009-12-24	Substituted tetrahydropyrrolopyrazine compounds having affinity with the kcnq2/3 k+ channel and use thereof in medicaments
GEP20135983B (en)	2013-12-10	1-benzyl-3-hydroxymethylindazole derivatives and usage therein treatment of diseases based on mcp-1, cx3cr1 and p40 expression
GEP20135927B (en)	2013-10-10	1-benzyl-3-hydroxymethylindaz-ole derivatives and usage thereat treatment of diseases based on mcp-1, cx3cr1 and p40 expression
NO20091955L (no)	2009-09-04	Antivirale sammensetninger, og fremgangsmater for anvendelse
EA200800501A1 (ru)	2008-10-30	Производные хинолина в качестве антибактериальных средств
TW200734344A (en)	2007-09-16	Antibacterial agents
WO2007143557A3 (en)	2008-05-08	Compounds and methods for treating mammalian gastrointestinal parasitic infections
DK1901723T3 (da)	2011-06-06	Antimikrobielle materialer
WO2007017267A3 (en)	2007-04-26	Novel compounds
WO2008005686A8 (en)	2009-02-05	Compositions comprising a dissociated glucocorticoid receptor agonist and an immunosuppressive agent for treating dry eye
MY159560A (en)	2017-01-13	Quinoline derivatives as antibacterial agents
IL188917A0 (en)	2008-04-13	2-hydroxy-propionic acid derivatives and 3-hydroxy-benzofuran-2-one derivatives with affinity for the gaba-b-receptor
CL2008003602A1 (es)	2009-10-09	Compuestos derivados de triazolotriazinas y triazolopirazinas sustituidas; composicion farmaceutica; y su uso en el tratamiento y/o profilaxis de trastornos hematologicos.
EA201100645A1 (ru)	2011-10-31	Композиции для местного применения, содержащие активные агенты с покрытием
WO2008144347A8 (en)	2010-02-25	Combinations comprising a fluoroquinolone for treating, reducing, ameliorating, or preventing infections