PL2049112T3 - Leczenie infekcji i ich następstw za pomocą połączonych zdysocjowanych agonistów receptora glukokortykoidowego i środków przeciwzapalnych - Google Patents
Leczenie infekcji i ich następstw za pomocą połączonych zdysocjowanych agonistów receptora glukokortykoidowego i środków przeciwzapalnychInfo
- Publication number
- PL2049112T3 PL2049112T3 PL07813634T PL07813634T PL2049112T3 PL 2049112 T3 PL2049112 T3 PL 2049112T3 PL 07813634 T PL07813634 T PL 07813634T PL 07813634 T PL07813634 T PL 07813634T PL 2049112 T3 PL2049112 T3 PL 2049112T3
- Authority
- PL
- Poland
- Prior art keywords
- glucocorticoid receptor
- sequelae
- combined
- receptor agonists
- infective agents
- Prior art date
Links
- 229960005475 antiinfective agent Drugs 0.000 title abstract 2
- 239000004599 antimicrobial Substances 0.000 title abstract 2
- 229940124750 glucocorticoid receptor agonist Drugs 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- JFUAWXPBHXKZGA-IBGZPJMESA-N 4-fluoro-2-[(4r)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-(1h-pyrrolo[2,3-c]pyridin-2-ylmethyl)pentan-2-yl]phenol Chemical compound C([C@@](O)(CC=1NC2=CN=CC=C2C=1)C(F)(F)F)C(C)(C)C1=CC(F)=CC=C1O JFUAWXPBHXKZGA-IBGZPJMESA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83611006P | 2006-08-07 | 2006-08-07 | |
| EP07813634A EP2049112B1 (en) | 2006-08-07 | 2007-08-01 | Treating infections and sequelae thereof with combined dissociated glucocorticoid receptor agonists and anti-infective agents |
| PCT/US2007/074936 WO2008021728A2 (en) | 2006-08-07 | 2007-08-01 | Treating infections and sequelae thereof with combined dissociated' glucocorticoid receptor agonists and anti-infective agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2049112T3 true PL2049112T3 (pl) | 2012-07-31 |
Family
ID=38823623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07813634T PL2049112T3 (pl) | 2006-08-07 | 2007-08-01 | Leczenie infekcji i ich następstw za pomocą połączonych zdysocjowanych agonistów receptora glukokortykoidowego i środków przeciwzapalnych |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20080033008A1 (pl) |
| EP (2) | EP2364707B1 (pl) |
| JP (1) | JP2010500363A (pl) |
| KR (1) | KR20090040369A (pl) |
| CN (1) | CN101522196A (pl) |
| AT (1) | ATE549022T1 (pl) |
| AU (1) | AU2007284175A1 (pl) |
| BR (1) | BRPI0714815A2 (pl) |
| CA (1) | CA2660151C (pl) |
| CY (1) | CY1113007T1 (pl) |
| DK (1) | DK2049112T3 (pl) |
| ES (2) | ES2381045T3 (pl) |
| MX (1) | MX2009001334A (pl) |
| PL (1) | PL2049112T3 (pl) |
| PT (1) | PT2049112E (pl) |
| SG (1) | SG174031A1 (pl) |
| SI (1) | SI2049112T1 (pl) |
| TW (1) | TWI343918B (pl) |
| WO (1) | WO2008021728A2 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090042936A1 (en) * | 2007-08-10 | 2009-02-12 | Ward Keith W | Compositions and Methods for Treating or Controlling Anterior-Segment Inflammation |
| CA2723954A1 (en) * | 2008-05-19 | 2009-11-26 | Alcon Research, Ltd. | Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer |
| JP2011527709A (ja) * | 2008-07-10 | 2011-11-04 | インスパイアー ファーマシューティカルズ,インコーポレイティド | 眼瞼炎の治療方法 |
| EP2393355A4 (en) * | 2009-01-23 | 2012-07-25 | Inspire Pharmaceuticals Inc | METHOD FOR TREATING A DRY EYE WITH AZITHROMYCIN |
| US20100247606A1 (en) * | 2009-03-25 | 2010-09-30 | Allergan, Inc. | Intraocular sustained release drug delivery systems and methods for treating ocular conditions |
| US20110077270A1 (en) * | 2009-04-21 | 2011-03-31 | Pfeffer Bruce A | Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure |
| GR1008168B (el) * | 2013-03-14 | 2014-04-08 | "Φαρματεν Α.Β.Ε.Ε.", | Παρεντερικο σκευασμα αντιβακτηριακου παραγοντα φθοριοκινολονης και μεθοδος για την παρασκευη αυτου |
| CA3123490A1 (en) | 2019-01-22 | 2020-07-30 | Akribes Biomedical Gmbh | Selective glucocorticoid receptor modifiers for treating impaired skin wound healing |
| CN111686239B (zh) * | 2019-03-11 | 2021-12-24 | 中国科学院微生物研究所 | 抗真菌化合物的应用 |
| CN115516773A (zh) * | 2020-05-08 | 2022-12-23 | 瑞典爱立信有限公司 | 多功能aas接收机 |
| WO2021228349A1 (en) | 2020-05-11 | 2021-11-18 | Telefonaktiebolaget Lm Ericsson (Publ) | Efficient prach scheduling |
| WO2026019875A1 (en) * | 2024-07-17 | 2026-01-22 | Jnd Therapeutics, Inc. | Methods and formulations for treatment of liver cancer using trifluridine |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
| US6051576A (en) | 1994-01-28 | 2000-04-18 | University Of Kentucky Research Foundation | Means to achieve sustained release of synergistic drugs by conjugation |
| ES2079320B1 (es) * | 1994-05-17 | 1996-10-16 | Cusi Lab | Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones. |
| US5773019A (en) * | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
| US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
| US6242196B1 (en) * | 1997-12-11 | 2001-06-05 | Dana-Farber Cancer Institute | Methods and pharmaceutical compositions for inhibiting tumor cell growth |
| WO2000000194A1 (en) * | 1998-06-27 | 2000-01-06 | Photogenesis, Inc. | Ophthalmic uses of ppargamma agonists and ppargamma antagonists |
| US6716830B2 (en) * | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| US6726918B1 (en) | 2000-07-05 | 2004-04-27 | Oculex Pharmaceuticals, Inc. | Methods for treating inflammation-mediated conditions of the eye |
| PE20020578A1 (es) * | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
| CA2443937A1 (en) * | 2001-04-23 | 2002-10-31 | Randall D. Glickman | Prostanoids augment ocular drug penetration |
| US7216711B2 (en) * | 2002-01-08 | 2007-05-15 | Halliburton Eenrgy Services, Inc. | Methods of coating resin and blending resin-coated proppant |
| AU2003202216A1 (en) * | 2002-01-14 | 2003-07-30 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof |
| CA2478156C (en) * | 2002-03-26 | 2011-02-15 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| WO2003082787A1 (en) | 2002-03-26 | 2003-10-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US6897224B2 (en) | 2002-04-02 | 2005-05-24 | Schering Ag | Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors |
| US7074806B2 (en) * | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| JP4503436B2 (ja) * | 2002-07-08 | 2010-07-14 | ファイザー・プロダクツ・インク | 糖質コルチコイド受容体のモジュレーター |
| CA2512257A1 (en) * | 2003-01-03 | 2004-07-29 | Boehringer Ingelheim Pharmaceuticals, Inc. | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands |
| US20040224992A1 (en) | 2003-02-27 | 2004-11-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| WO2004097410A1 (en) | 2003-04-30 | 2004-11-11 | Pfizer Products Inc. | Screening methods for cataractogenic risk |
| UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
| US7605264B2 (en) * | 2004-01-16 | 2009-10-20 | Bristol-Myers Squibb Company | Heterocyclic modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof |
| US7795272B2 (en) * | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| EP1730145A1 (en) * | 2004-03-22 | 2006-12-13 | Boehringer Ingelheim Pharmaceuticals Inc. | Alpha-trifluoromethyl alcohols or amines as glucocorticoid mimetics |
| US7417056B2 (en) * | 2004-11-12 | 2008-08-26 | Schering Ag | 5-substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents |
| DE102004055633A1 (de) | 2004-11-12 | 2006-05-18 | Schering Ag | 5-substituierte Chinolin- und Isochinolin-Derivate, ein Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| CA2592514A1 (en) | 2004-12-27 | 2006-07-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| CN101484187B (zh) * | 2006-07-07 | 2012-12-26 | 博士伦公司 | 包含解离的糖皮质激素受体激动剂和免疫抑制剂的用于治疗干眼症的组合物 |
-
2007
- 2007-08-01 BR BRPI0714815-1A patent/BRPI0714815A2/pt not_active IP Right Cessation
- 2007-08-01 EP EP11169315A patent/EP2364707B1/en not_active Not-in-force
- 2007-08-01 PL PL07813634T patent/PL2049112T3/pl unknown
- 2007-08-01 AU AU2007284175A patent/AU2007284175A1/en not_active Abandoned
- 2007-08-01 SG SG2011055688A patent/SG174031A1/en unknown
- 2007-08-01 AT AT07813634T patent/ATE549022T1/de active
- 2007-08-01 CN CNA2007800366571A patent/CN101522196A/zh active Pending
- 2007-08-01 US US11/832,265 patent/US20080033008A1/en not_active Abandoned
- 2007-08-01 CA CA2660151A patent/CA2660151C/en not_active Expired - Fee Related
- 2007-08-01 DK DK07813634.8T patent/DK2049112T3/da active
- 2007-08-01 ES ES07813634T patent/ES2381045T3/es active Active
- 2007-08-01 EP EP07813634A patent/EP2049112B1/en not_active Not-in-force
- 2007-08-01 WO PCT/US2007/074936 patent/WO2008021728A2/en not_active Ceased
- 2007-08-01 JP JP2009523900A patent/JP2010500363A/ja active Pending
- 2007-08-01 PT PT07813634T patent/PT2049112E/pt unknown
- 2007-08-01 KR KR1020097004767A patent/KR20090040369A/ko not_active Ceased
- 2007-08-01 MX MX2009001334A patent/MX2009001334A/es active IP Right Grant
- 2007-08-01 SI SI200730912T patent/SI2049112T1/sl unknown
- 2007-08-01 ES ES11169315T patent/ES2403512T3/es active Active
- 2007-08-06 TW TW096128888A patent/TWI343918B/zh not_active IP Right Cessation
-
2012
- 2012-05-25 CY CY20121100476T patent/CY1113007T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2660151A1 (en) | 2008-02-21 |
| EP2049112A2 (en) | 2009-04-22 |
| SG174031A1 (en) | 2011-09-29 |
| MX2009001334A (es) | 2009-02-13 |
| DK2049112T3 (da) | 2012-04-23 |
| US20080033008A1 (en) | 2008-02-07 |
| ES2403512T3 (es) | 2013-05-20 |
| CA2660151C (en) | 2012-04-17 |
| KR20090040369A (ko) | 2009-04-23 |
| WO2008021728A3 (en) | 2008-10-09 |
| JP2010500363A (ja) | 2010-01-07 |
| EP2364707A3 (en) | 2011-12-28 |
| EP2364707A2 (en) | 2011-09-14 |
| HK1131046A1 (en) | 2010-01-15 |
| EP2049112B1 (en) | 2012-03-14 |
| BRPI0714815A2 (pt) | 2013-05-21 |
| TWI343918B (en) | 2011-06-21 |
| SI2049112T1 (sl) | 2012-05-31 |
| AU2007284175A1 (en) | 2008-02-21 |
| WO2008021728A2 (en) | 2008-02-21 |
| CN101522196A (zh) | 2009-09-02 |
| TW200815410A (en) | 2008-04-01 |
| PT2049112E (pt) | 2012-06-05 |
| ATE549022T1 (de) | 2012-03-15 |
| ES2381045T3 (es) | 2012-05-22 |
| CY1113007T1 (el) | 2016-04-13 |
| EP2364707B1 (en) | 2013-04-03 |
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