ATE549022T1 - Behandlung von infektionen und deren folgeleiden mit kombinierten dissoziierten glocucorticoid- rezeptor-agonisten und antiinfektionswirkstoffen - Google Patents

Behandlung von infektionen und deren folgeleiden mit kombinierten dissoziierten glocucorticoid- rezeptor-agonisten und antiinfektionswirkstoffen

Info

Publication number: ATE549022T1
Authority: AT; Austria
Prior art keywords: infections; glocucorticoid; dissociate; consequences; treatment
Prior art date: 2006-08-07

Application number

AT07813634T

Other languages

English (en)

Inventor

Zhenze Hu

Keith Ward

Gary Phillips

Raili Kerppola

Original Assignee

Bausch & Lomb

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-08-07

Filing date

2007-08-01

Publication date

2012-03-15

2007-08-01 Application filed by Bausch & Lomb filed Critical Bausch & Lomb

2012-03-15 Application granted granted Critical

2012-03-15 Publication of ATE549022T1 publication Critical patent/ATE549022T1/de

Links

208000015181 infectious disease Diseases 0.000 title abstract 2
230000002924 anti-infective effect Effects 0.000 title 1
239000000018 receptor agonist Substances 0.000 title 1
229940044601 receptor agonist Drugs 0.000 title 1
239000000203 mixture Substances 0.000 abstract 2
JFUAWXPBHXKZGA-IBGZPJMESA-N 4-fluoro-2-[(4r)-5,5,5-trifluoro-4-hydroxy-2-methyl-4-(1h-pyrrolo[2,3-c]pyridin-2-ylmethyl)pentan-2-yl]phenol Chemical compound C([C@@](O)(CC=1NC2=CN=CC=C2C=1)C(F)(F)F)C(C)(C)C1=CC(F)=CC=C1O JFUAWXPBHXKZGA-IBGZPJMESA-N 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
229960005475 antiinfective agent Drugs 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
239000003904 antiprotozoal agent Substances 0.000 abstract 1
229940124750 glucocorticoid receptor agonist Drugs 0.000 abstract 1
238000002513 implantation Methods 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
230000000699 topical effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/04—Amoebicides

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Bioinformatics & Cheminformatics (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)
Ophthalmology & Optometry (AREA)
Rheumatology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Plural Heterocyclic Compounds (AREA)

AT07813634T 2006-08-07 2007-08-01 Behandlung von infektionen und deren folgeleiden mit kombinierten dissoziierten glocucorticoid- rezeptor-agonisten und antiinfektionswirkstoffen ATE549022T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US83611006P	2006-08-07	2006-08-07
PCT/US2007/074936 WO2008021728A2 (en)	2006-08-07	2007-08-01	Treating infections and sequelae thereof with combined dissociated' glucocorticoid receptor agonists and anti-infective agents

Publications (1)

Publication Number	Publication Date
ATE549022T1 true ATE549022T1 (de)	2012-03-15

Family

ID=38823623

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07813634T ATE549022T1 (de)	2006-08-07	2007-08-01	Behandlung von infektionen und deren folgeleiden mit kombinierten dissoziierten glocucorticoid- rezeptor-agonisten und antiinfektionswirkstoffen

Country Status (19)

Country	Link
US (1)	US20080033008A1 (de)
EP (2)	EP2364707B1 (de)
JP (1)	JP2010500363A (de)
KR (1)	KR20090040369A (de)
CN (1)	CN101522196A (de)
AT (1)	ATE549022T1 (de)
AU (1)	AU2007284175A1 (de)
BR (1)	BRPI0714815A2 (de)
CA (1)	CA2660151C (de)
CY (1)	CY1113007T1 (de)
DK (1)	DK2049112T3 (de)
ES (2)	ES2381045T3 (de)
MX (1)	MX2009001334A (de)
PL (1)	PL2049112T3 (de)
PT (1)	PT2049112E (de)
SG (1)	SG174031A1 (de)
SI (1)	SI2049112T1 (de)
TW (1)	TWI343918B (de)
WO (1)	WO2008021728A2 (de)

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JP2011527709A (ja) *	2008-07-10	2011-11-04	インスパイアーファーマシューティカルズ，インコーポレイティド	眼瞼炎の治療方法
EP2393355A4 (de) *	2009-01-23	2012-07-25	Inspire Pharmaceuticals Inc	Verfahren zur behandlung von trockenem auge mit azithromycin
US20100247606A1 (en) *	2009-03-25	2010-09-30	Allergan, Inc.	Intraocular sustained release drug delivery systems and methods for treating ocular conditions
US20110077270A1 (en) *	2009-04-21	2011-03-31	Pfeffer Bruce A	Compositions and Methods for Treating Ocular Inflammation with Lower Risk of Increased Intraocular Pressure
GR1008168B (el) *	2013-03-14	2014-04-08	"Φαρματεν Α.Β.Ε.Ε.",	Παρεντερικο σκευασμα αντιβακτηριακου παραγοντα φθοριοκινολονης και μεθοδος για την παρασκευη αυτου
CA3123490A1 (en)	2019-01-22	2020-07-30	Akribes Biomedical Gmbh	Selective glucocorticoid receptor modifiers for treating impaired skin wound healing
CN111686239B (zh) *	2019-03-11	2021-12-24	中国科学院微生物研究所	抗真菌化合物的应用
CN115516773A (zh) *	2020-05-08	2022-12-23	瑞典爱立信有限公司	多功能aas接收机
WO2021228349A1 (en)	2020-05-11	2021-11-18	Telefonaktiebolaget Lm Ericsson (Publ)	Efficient prach scheduling
WO2026019875A1 (en) *	2024-07-17	2026-01-22	Jnd Therapeutics, Inc.	Methods and formulations for treatment of liver cancer using trifluridine

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2007
- 2007-08-01 BR BRPI0714815-1A patent/BRPI0714815A2/pt not_active IP Right Cessation
- 2007-08-01 EP EP11169315A patent/EP2364707B1/de not_active Not-in-force
- 2007-08-01 PL PL07813634T patent/PL2049112T3/pl unknown
- 2007-08-01 AU AU2007284175A patent/AU2007284175A1/en not_active Abandoned
- 2007-08-01 SG SG2011055688A patent/SG174031A1/en unknown
- 2007-08-01 AT AT07813634T patent/ATE549022T1/de active
- 2007-08-01 CN CNA2007800366571A patent/CN101522196A/zh active Pending
- 2007-08-01 US US11/832,265 patent/US20080033008A1/en not_active Abandoned
- 2007-08-01 CA CA2660151A patent/CA2660151C/en not_active Expired - Fee Related
- 2007-08-01 DK DK07813634.8T patent/DK2049112T3/da active
- 2007-08-01 ES ES07813634T patent/ES2381045T3/es active Active
- 2007-08-01 EP EP07813634A patent/EP2049112B1/de not_active Not-in-force
- 2007-08-01 WO PCT/US2007/074936 patent/WO2008021728A2/en not_active Ceased
- 2007-08-01 JP JP2009523900A patent/JP2010500363A/ja active Pending
- 2007-08-01 PT PT07813634T patent/PT2049112E/pt unknown
- 2007-08-01 KR KR1020097004767A patent/KR20090040369A/ko not_active Ceased
- 2007-08-01 MX MX2009001334A patent/MX2009001334A/es active IP Right Grant
- 2007-08-01 SI SI200730912T patent/SI2049112T1/sl unknown
- 2007-08-01 ES ES11169315T patent/ES2403512T3/es active Active
- 2007-08-06 TW TW096128888A patent/TWI343918B/zh not_active IP Right Cessation
2012
- 2012-05-25 CY CY20121100476T patent/CY1113007T1/el unknown

Also Published As

Publication number	Publication date
CA2660151A1 (en)	2008-02-21
PL2049112T3 (pl)	2012-07-31
EP2049112A2 (de)	2009-04-22
SG174031A1 (en)	2011-09-29
MX2009001334A (es)	2009-02-13
DK2049112T3 (da)	2012-04-23
US20080033008A1 (en)	2008-02-07
ES2403512T3 (es)	2013-05-20
CA2660151C (en)	2012-04-17
KR20090040369A (ko)	2009-04-23
WO2008021728A3 (en)	2008-10-09
JP2010500363A (ja)	2010-01-07
EP2364707A3 (de)	2011-12-28
EP2364707A2 (de)	2011-09-14
HK1131046A1 (en)	2010-01-15
EP2049112B1 (de)	2012-03-14
BRPI0714815A2 (pt)	2013-05-21
TWI343918B (en)	2011-06-21
SI2049112T1 (sl)	2012-05-31
AU2007284175A1 (en)	2008-02-21
WO2008021728A2 (en)	2008-02-21
CN101522196A (zh)	2009-09-02
TW200815410A (en)	2008-04-01
PT2049112E (pt)	2012-06-05
ES2381045T3 (es)	2012-05-22
CY1113007T1 (el)	2016-04-13
EP2364707B1 (de)	2013-04-03

Publication	Publication Date	Title
ATE549022T1 (de)	2012-03-15	Behandlung von infektionen und deren folgeleiden mit kombinierten dissoziierten glocucorticoid- rezeptor-agonisten und antiinfektionswirkstoffen
AR051322A1 (es)	2007-01-03	Composiciones de amitraz
BRPI0706676B8 (pt)	2021-05-25	uso de uma solução aquosa com potencial de oxirredução
EA200802166A1 (ru)	2009-06-30	Стабильная фармацевтическая композиция с защитным действием от раздражения (варианты), способ ее получения и способ лечения кальций-миметиком с ее помощью
CL2012000623A1 (es)	2012-09-14	Compuestos derivados de 4-[4,4-dimetil-5oxo-3-(piridin-ilmetil)-2-tioxoimidazolidin-1-il]-2-(trifluorometil)benzonitrilo, con propiedades antiandrogenicas; metodo de preparacion; composcion farmaceutica; y su uso para el tratamiento y/o profilaxis de cancer de prostata.
ECSP088763A (es)	2008-10-31	Nuevas combinaciones terapéuticas para el tratamiento de la depresión
EA033311B1 (ru)	2019-09-30	Производные бензоксаборола в качестве антибактериальных средств
EA200870391A1 (ru)	2009-06-30	Тетрагидропирролопиримидиндионы и их применение в качестве ингибиторов эластазы нейтрофилов человека
BRPI0813450B8 (pt)	2021-05-25	composto, formulação farmacêutica, e, usos do composto
DE602004021644D1 (de)	2009-07-30	Gyraseinhibitoren und deren verwendungen
NO20023473D0 (no)	2002-07-19	Sammensetninger for levering av en kortisol antagonist
SI2051710T1 (sl)	2012-02-29	Sestavki in postopki za zdravljenje, zmanjšanje, izboljšanje ali lajšanje oftalmičnih bolezni posteriornega segmenta
GEP20135927B (en)	2013-10-10	1-benzyl-3-hydroxymethylindaz-ole derivatives and usage thereat treatment of diseases based on mcp-1, cx3cr1 and p40 expression
WO2007143557A3 (en)	2008-05-08	Compounds and methods for treating mammalian gastrointestinal parasitic infections
CL2008002429A1 (es)	2009-01-02	Compuestos derivados de n-bencil, n'-arilcarbonilpiperazina, con actividad agonista de los receptores x del higado (lxrs); composicion farmaceutica que los contiene; y el uso de los compuestos en el tratamiento de la aterosclerosis.
SE0300971D0 (sv)	2003-04-03	Nitric oxide in treatment of inflammation
NO20045215L (no)	2005-03-17	Anvendelse av tio-oxindolderivater for behandling av hudlidelser
BR112019003136A2 (pt)	2019-05-21	forma de dosagem multiunitária de composição farmacêutica, forma de dosagem unitária de composição farmacêutica, forma de dosagem multiunitária / unitária, kit e método de tratamento de uma condição tratável por administração oral de um agente terapeuticamente ativo
TW200734344A (en)	2007-09-16	Antibacterial agents
CL2011003327A1 (es)	2013-01-25	Composicion farmaceutica que comprende finafloxacina y un agente antiinflamatorio; uso en el tratamiento de infecciones oftalmicas, oticas o nasales.
NO20092073L (no)	2009-06-26	Modulatorer av C3A-reseptor, og fremgangsmater for anvendelse derav
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