DK207688A - Quinolinderivater - Google Patents

Quinolinderivater

Info

Publication number
DK207688A
DK207688A DK207688A DK207688A DK207688A DK 207688 A DK207688 A DK 207688A DK 207688 A DK207688 A DK 207688A DK 207688 A DK207688 A DK 207688A DK 207688 A DK207688 A DK 207688A
Authority
DK
Denmark
Prior art keywords
quinoline
Prior art date
Application number
DK207688A
Other languages
English (en)
Other versions
DK170640B1 (da
DK207688D0 (da
Inventor
Hiraki Ueda
Hisashi Miyamoto
Hiroshi Yamashita
Hitoshi Tone
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of DK207688D0 publication Critical patent/DK207688D0/da
Publication of DK207688A publication Critical patent/DK207688A/da
Application granted granted Critical
Publication of DK170640B1 publication Critical patent/DK170640B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK207688A 1987-04-16 1988-04-15 Quinolinderivater DK170640B1 (da)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
JP9419887 1987-04-16
JP9419887 1987-04-16
JP10235187 1987-04-24
JP10235187 1987-04-24
JP10836187 1987-04-30
JP10836187 1987-04-30
JP12659887 1987-05-22
JP12659887 1987-05-22
JP14954487 1987-06-16
JP14954487 1987-06-16
JP17612687 1987-07-14
JP17612687 1987-07-14
JP28377687 1987-11-09
JP28377687 1987-11-09
JP28710887 1987-11-12
JP28710887 1987-11-12

Publications (3)

Publication Number Publication Date
DK207688D0 DK207688D0 (da) 1988-04-15
DK207688A true DK207688A (da) 1988-10-17
DK170640B1 DK170640B1 (da) 1995-11-20

Family

ID=27572879

Family Applications (2)

Application Number Title Priority Date Filing Date
DK207688A DK170640B1 (da) 1987-04-16 1988-04-15 Quinolinderivater
DK101492A DK171820B1 (da) 1987-04-16 1992-08-13 Quinolinderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK101492A DK171820B1 (da) 1987-04-16 1992-08-13 Quinolinderivater

Country Status (13)

Country Link
US (5) US5563138A (da)
EP (3) EP0565132B1 (da)
JP (2) JPH0696557B2 (da)
KR (2) KR940002113B1 (da)
CN (1) CN1053666C (da)
CY (1) CY2050B1 (da)
DE (4) DE19775083I2 (da)
DK (2) DK170640B1 (da)
ES (3) ES2152936T3 (da)
HK (1) HK128797A (da)
NL (1) NL980011I2 (da)
SA (1) SA97180461A (da)
SG (3) SG97777A1 (da)

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US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
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ES2147721T3 (es) 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
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DE69231422T2 (de) * 1991-05-28 2001-03-29 Daiichi Pharmaceutical Co., Ltd. Pyridoncarbonsäurederivate
FR2692577B1 (fr) * 1992-05-26 1996-02-02 Bouchara Sa Nouvelles quinolones fluorees, leur procede de preparation et les compositions pharmaceutiques en renfermant.
ES2140531T3 (es) * 1993-03-10 2000-03-01 Otsuka Pharma Co Ltd Inhibidor de la interleucina-1.
DE4329600A1 (de) * 1993-09-02 1995-03-09 Bayer Ag Pyrido [1,2,3-d,e] [1,3,4] benzoxadiazinderivate
DE69428206T2 (de) * 1993-10-28 2002-06-13 Kaken Pharmaceutical Co., Ltd. Chinolincarbonsäurederivate und ihre salze
DE4408212A1 (de) * 1994-03-11 1995-09-14 Bayer Ag 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren
DE4431821A1 (de) * 1994-09-07 1996-03-14 Bayer Ag Verfahren zur Herstellung von N-Arylaminoacrylsäurederivaten und die Verwendung so hergestellter N-Arylaminoacrylsäurederivate zur Herstellung von 4-Chinolon-3-carbonsäurederivaten
KR19980701625A (ko) * 1995-01-24 1998-06-25 이토 마사노리 퀴놀린카르본산유도체
US6136823A (en) * 1996-11-28 2000-10-24 Wakunaga Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives or salts thereof and drugs containing the same as the active ingredient
DE19652239A1 (de) 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
ATE365152T1 (de) * 1998-09-14 2007-07-15 Otsuka Pharma Co Ltd Verfahren zur herstellung fluorierter benzoesäuren
WO2000018404A1 (en) * 1998-09-30 2000-04-06 Alcon Laboratories, Inc. Antibiotic compositions for treatment of the eye, ear and nose
US6716830B2 (en) 1998-09-30 2004-04-06 Alcon, Inc. Ophthalmic antibiotic compositions containing moxifloxacin
US6395746B1 (en) 1998-09-30 2002-05-28 Alcon Manufacturing, Ltd. Methods of treating ophthalmic, otic and nasal infections and attendant inflammation
US6509327B1 (en) 1998-09-30 2003-01-21 Alcon Manufacturing, Ltd. Compositions and methods for treating otic, ophthalmic and nasal infections
DE19850788A1 (de) * 1998-11-04 2000-05-11 Clariant Gmbh Verfahren zur Herstellung von Trifluorbenzoesäuren
AU3192700A (en) 1999-03-17 2000-10-04 Daiichi Pharmaceutical Co., Ltd. Medicinal compositions
DE19962470A1 (de) * 1999-12-22 2001-07-12 Schulz Hans Herrmann Verwendung von Chemotherapeutika
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
AU2002239395A1 (en) * 2000-11-01 2002-06-03 The Procter And Gamble Company Hiv treatment with benzimidazoles
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
AU2003220585A1 (en) * 2002-03-26 2003-10-13 Arizona Board of Regents on behalf of the University of Arizone Solubilization of weak bases
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
SK2662004A3 (sk) 2002-11-20 2005-06-02 Japan Tobacco, Inc. Zlúčenina s obsahom 4-oxochinolínu a jej použitie ako inhibítora integráz
JP5255183B2 (ja) 2003-09-04 2013-08-07 ウォックハート リミテッド ベンゾキノリジン−２−カルボン酸アルギニン塩四水和物
WO2005026147A1 (ja) 2003-09-10 2005-03-24 Kyorin Pharmaceutical Co., Ltd. ７−（４−置換−３−シクロプロピルアミノメチル−１−ピロリジニル）キノロンカルボン酸誘導体
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WO2007102499A1 (ja) 2006-03-06 2007-09-13 Japan Tobacco Inc. ４－オキソキノリン化合物の製造方法
KR101438036B1 (ko) 2006-09-29 2014-09-04 씨아이피엘에이 엘티디. 테모졸로미드 및 유사체의 개선된 제조방법
JP5322927B2 (ja) * 2007-05-24 2013-10-23 杏林製薬株式会社 １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
EP2222662A4 (en) * 2007-11-15 2011-08-03 Univ Maryland INHIBITORS OF KYNURENINE AMINO TRANSFERASE
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CN106913569B (zh) * 2016-01-04 2022-04-22 广东工业大学 苯酞类化合物在制备抗耐药菌药物中的应用
CN112266326A (zh) * 2020-11-10 2021-01-26 杭州臻挚生物科技有限公司 二氯甲苯硝化物中间体的制备方法

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Also Published As

Publication number Publication date
DE19775083I2 (de) 2001-06-13
EP0565132A2 (en) 1993-10-13
JP2654537B2 (ja) 1997-09-17
ES2152936T3 (es) 2001-02-16
SA97180461A (ar) 2005-12-03
CY2050B1 (en) 1998-04-30
SG101541A1 (en) 2004-01-30
JPH0696557B2 (ja) 1994-11-30
DE3856515D1 (de) 2002-03-21
ES2091180T3 (es) 1996-11-01
SG49836A1 (en) 1998-06-15
CN1030237A (zh) 1989-01-11
DK171820B1 (da) 1997-06-23
EP0565132A3 (en) 1994-05-18
DK170640B1 (da) 1995-11-20
HK128797A (en) 1997-09-19
EP0287951B1 (en) 1996-07-03
EP0565132B1 (en) 2000-10-25
US5811576A (en) 1998-09-22
DE3855388T2 (de) 1997-02-13
DK101492A (da) 1992-08-13
DE3855388D1 (de) 1996-08-08
ES2172734T3 (es) 2002-10-01
EP0823413A2 (en) 1998-02-11
DK101492D0 (da) 1992-08-13
NL980011I1 (nl) 1998-05-06
JPH01230558A (ja) 1989-09-14
EP0287951A3 (en) 1990-06-13
SG97777A1 (en) 2003-08-20
US5591744A (en) 1997-01-07
EP0823413A3 (en) 1998-12-09
DE3856434T2 (de) 2001-06-13
JPH07138232A (ja) 1995-05-30
EP0823413B1 (en) 2002-02-13
KR880012506A (ko) 1988-11-28
US5495020A (en) 1996-02-27
KR940002113B1 (ko) 1994-03-17
CN1053666C (zh) 2000-06-21
DK207688D0 (da) 1988-04-15
KR960006145B1 (ko) 1996-05-09
NL980011I2 (nl) 1998-10-01
DE3856515T2 (de) 2002-08-14
US5723648A (en) 1998-03-03
DE3856434D1 (de) 2000-11-30
EP0287951A2 (en) 1988-10-26
US5563138A (en) 1996-10-08

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