DK2099460T3 - 6-alkoxyalkylestradiolderivater og fremgangsmåder til anvendelse - Google Patents

6-alkoxyalkylestradiolderivater og fremgangsmåder til anvendelse

Info

Publication number
DK2099460T3
DK2099460T3 DK07868944.5T DK07868944T DK2099460T3 DK 2099460 T3 DK2099460 T3 DK 2099460T3 DK 07868944 T DK07868944 T DK 07868944T DK 2099460 T3 DK2099460 T3 DK 2099460T3
Authority
DK
Denmark
Prior art keywords
stradiold
alcoxylkyl
derivatives
methods
stradiold derivatives
Prior art date
Application number
DK07868944.5T
Other languages
English (en)
Inventor
James Yarger
Original Assignee
Endece Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endece Llc filed Critical Endece Llc
Application granted granted Critical
Publication of DK2099460T3 publication Critical patent/DK2099460T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK07868944.5T 2006-11-30 2007-11-29 6-alkoxyalkylestradiolderivater og fremgangsmåder til anvendelse DK2099460T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86798006P 2006-11-30 2006-11-30
PCT/US2007/085913 WO2008067450A2 (en) 2006-11-30 2007-11-29 6-alkoxyalkyl estradiol derivatives and methods of use

Publications (1)

Publication Number Publication Date
DK2099460T3 true DK2099460T3 (da) 2017-01-02

Family

ID=39468717

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07868944.5T DK2099460T3 (da) 2006-11-30 2007-11-29 6-alkoxyalkylestradiolderivater og fremgangsmåder til anvendelse

Country Status (11)

Country Link
EP (1) EP2099460B1 (da)
JP (1) JP5290189B2 (da)
KR (1) KR101499266B1 (da)
CN (1) CN101594874B (da)
AU (1) AU2007325092B2 (da)
BR (1) BRPI0721050A2 (da)
CA (1) CA2670773C (da)
DK (1) DK2099460T3 (da)
ES (1) ES2604079T3 (da)
MX (1) MX342437B (da)
WO (1) WO2008067450A2 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10174070B2 (en) 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
BR112013005843A2 (pt) * 2010-09-14 2019-12-10 Endece Llc derivativos de er-beta 6-substituído por desmetil-estradiol
CN106420767A (zh) * 2011-03-21 2017-02-22 安德斯有限责任公司 用于神经轴突的髓鞘再生的6‑取代的雌二醇衍生物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3377363A (en) 1966-04-13 1968-04-09 Abbott Lab delta5(10)-6-hydroxymethyl-estrene compounds
DD258820A1 (de) * 1986-06-13 1988-08-03 Adw Ddr Verfahren zur herstellung von 6beta-hydroxy-methyl-androsta-1,4-dien-3,17-dion
US5504074A (en) * 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
DE19633349A1 (de) 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten
IT1317031B1 (it) 2000-05-17 2003-05-26 Sigma Tau Ind Farmaceuti Procedimento migliorato per la preparazione di (e,z)3-(2-amminoetossimmino)-androstano-6, 17-dione e di suoi analoghi.
ATE548375T1 (de) * 2004-01-16 2012-03-15 Cedarburg Pharmaceuticals Inc Exemestan und zwischenprodukte davon und verfahren zu dessen herstellung
US7419972B2 (en) * 2004-07-02 2008-09-02 Schering Ag 2-substituted estra-1,3,5(10)-trien-17-ones as inhibitors of 17β-hydroxy steroid dehydrogenase type 1
BRPI0616639A2 (pt) * 2005-09-30 2011-06-28 Endece Llc compostos de exemestano de (s)-6-metiloxaalquila e métodos de uso relacionados
TWI392682B (zh) * 2006-04-13 2013-04-11 Sigma Tau Ind Farmaceuti 作為心血管疾病的治療藥物之雄甾烷和雄甾烯的胺基衍生物

Also Published As

Publication number Publication date
KR101499266B1 (ko) 2015-03-05
EP2099460A4 (en) 2010-03-24
KR20090101914A (ko) 2009-09-29
EP2099460B1 (en) 2016-09-07
AU2007325092A1 (en) 2008-06-05
CA2670773A1 (en) 2008-06-05
CN101594874B (zh) 2017-02-08
AU2007325092B2 (en) 2013-04-11
WO2008067450A3 (en) 2008-07-17
MX342437B (es) 2016-09-29
JP5290189B2 (ja) 2013-09-18
WO2008067450A2 (en) 2008-06-05
EP2099460A2 (en) 2009-09-16
BRPI0721050A2 (pt) 2014-07-29
ES2604079T3 (es) 2017-03-02
JP2010511625A (ja) 2010-04-15
MX2009005803A (es) 2009-08-26
CN101594874A (zh) 2009-12-02
CA2670773C (en) 2013-01-22

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