DK211283A - Benzothiazolinforbindelser - Google Patents

Benzothiazolinforbindelser Download PDF

Info

Publication number: DK211283A
Authority: DK; Denmark
Prior art keywords: hydrogen; image; substituted; alkyl; hydroxyl
Prior art date: 1981-09-12

Application number

DK211283A

Other languages

English (en)

Other versions

DK211283D0 (da

DK164403C (da

DK164403B (da

Inventor

Jun-Ichi Iwao

Tadashi Iso

Masayuki Oya

Original Assignee

Santen Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-09-12

Filing date

1983-05-11

Publication date

1983-05-11

1983-05-11 Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd

1983-05-11 Publication of DK211283D0 publication Critical patent/DK211283D0/da

1983-05-11 Publication of DK211283A publication Critical patent/DK211283A/da

1992-06-22 Publication of DK164403B publication Critical patent/DK164403B/da

1992-11-16 Application granted granted Critical

1992-11-16 Publication of DK164403C publication Critical patent/DK164403C/da

Links

IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
125000001589 carboacyl group Chemical group 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
208000024172 Cardiovascular disease Diseases 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
125000001188 haloalkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000547 substituted alkyl group Chemical group 0.000 abstract 1
-1 sulphamoyl Chemical group 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK211283A 1981-09-12 1983-05-11 Analogifremgangsmaade til fremstilling af benzothiazolinderivater DK164403C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP14414881		1981-09-12
JP56144148A JPS5846079A (ja)	1981-09-12	1981-09-12	ベンゾチアゾリン環を有するエ−テル類
JP8200363		1982-09-10
PCT/JP1982/000363 WO1983000865A1 (fr)	1981-09-12	1982-09-10	Composes de benzothiazoline

Publications (4)

Publication Number	Publication Date
DK211283D0 DK211283D0 (da)	1983-05-11
DK211283A true DK211283A (da)	1983-05-11
DK164403B DK164403B (da)	1992-06-22
DK164403C DK164403C (da)	1992-11-16

Family

ID=15355326

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK211283A DK164403C (da)	1981-09-12	1983-05-11	Analogifremgangsmaade til fremstilling af benzothiazolinderivater

Country Status (18)

Country	Link
US (3)	US4479949A (da)
JP (1)	JPS5846079A (da)
AT (1)	AT379592B (da)
AU (1)	AU541223B2 (da)
BE (1)	BE894358A (da)
CA (1)	CA1169860A (da)
CH (1)	CH654001A5 (da)
DE (1)	DE3248957T1 (da)
DK (1)	DK164403C (da)
ES (2)	ES8308552A1 (da)
FI (1)	FI68232C (da)
FR (1)	FR2512820B1 (da)
GB (1)	GB2115815B (da)
IT (1)	IT1196423B (da)
NL (1)	NL8220310A (da)
NO (1)	NO831653L (da)
SE (1)	SE444681B (da)
WO (1)	WO1983000865A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS56164877A (en) *	1980-05-23	1981-12-18	Fujitsu Ltd	Manufacture of head for thermal printer
JPS5846079A (ja) *	1981-09-12	1983-03-17	Santen Pharmaceut Co Ltd	ベンゾチアゾリン環を有するエ−テル類
DK143684A (da) *	1983-03-12	1984-09-13	Bayer Ag	Anvendelse af pyrazolonderivater som lipoxygenasehaemmer ved terapi af isaer ischaemi og hjerterytmeforstyrrelser
JPS60139679A (ja) *	1983-12-27	1985-07-24	Santen Pharmaceut Co Ltd	２−アリ−ルベンゾチアゾリン誘導体
JPS60207396A (ja) *	1984-03-31	1985-10-18	ロ−ム株式会社	配線基板
JPS61110568A (ja) *	1984-10-31	1986-05-28	アルカテル・エヌ・ブイ	プリンタ装置
US4728651A (en) *	1985-10-24	1988-03-01	Hoechst-Roussel Pharmaceuticals Inc.	Antihypertensive thieno-isoxazoles and -pyrazoles
JPS62221679A (ja) *	1986-03-19	1987-09-29	Santen Pharmaceut Co Ltd	ベンゾチアゾリン誘導体
US5147881A (en) *	1990-11-14	1992-09-15	Pfizer Inc	4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5541204A (en) *	1994-12-02	1996-07-30	Bristol-Myers Squibb Company	Aryloxypropanolamine β 3 adrenergic agonists
EP1496053B1 (en)	2002-03-29	2012-06-20	Santen Pharmaceutical Co., Ltd.	Kappa-opioid receptor agonist comprising a 2-phenylbenzothiazoline derivative
CA2907921C (en) *	2013-03-22	2021-09-07	Ayumi Pharmaceutical Corporation	Inhibition of il-2 production

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2996512A (en) *		1961-08-15		Therapeutic derivatives of aryl-
US3117124A (en) *	1957-03-20	1964-01-07	Olin Mathieson	Benzothiazole, benzothiazine, and benzothiazepine compounds
FR1255312A (fr) *	1957-10-31	1961-03-10	Crookes Lab Ltd	Dérivés des aryl-benzothiazoles et leur mode de préparation
GB1058822A (en) *	1963-07-30	1967-02-15	Ici Ltd	3-amino-2-hydroxypropoxy heterocyclic derivatives
BE754245A (fr) *	1969-08-01	1970-12-31	Sumitomo Chemical Co	Derives d'acides phenoxy carboxyliques
US3574218A (en) *	1969-08-11	1971-04-06	Egyt Gyogyszervegyeszeti Gyar	2-aryl- or aralkyl-substituted benzazole derivatives
US3720683A (en) *	1970-09-02	1973-03-13	Squibb & Sons Inc	2-phenyl-3-acylbenzothiazolines and their oxides
JPS5371071A (en) *	1976-12-08	1978-06-24	Teijin Ltd	Alpha-phenoxyacetic acid derivs.
JPS57179175A (en) *	1981-04-30	1982-11-04	Shinzo Kano	Preparation of 2-benzothiazolinone derivative or salt thereof
JPS5846079A (ja) *	1981-09-12	1983-03-17	Santen Pharmaceut Co Ltd	ベンゾチアゾリン環を有するエ−テル類

1981
- 1981-09-12 JP JP56144148A patent/JPS5846079A/ja active Pending
1982
- 1982-09-07 IT IT23146/82A patent/IT1196423B/it active
- 1982-09-10 GB GB08311096A patent/GB2115815B/en not_active Expired
- 1982-09-10 CA CA000411159A patent/CA1169860A/en not_active Expired
- 1982-09-10 NL NL8220310A patent/NL8220310A/nl not_active Application Discontinuation
- 1982-09-10 ES ES515655A patent/ES8308552A1/es not_active Expired
- 1982-09-10 BE BE2/59831A patent/BE894358A/fr not_active IP Right Cessation
- 1982-09-10 AU AU89026/82A patent/AU541223B2/en not_active Ceased
- 1982-09-10 US US06/503,160 patent/US4479949A/en not_active Expired - Lifetime
- 1982-09-10 AT AT0904882A patent/AT379592B/de not_active IP Right Cessation
- 1982-09-10 CH CH2716/83A patent/CH654001A5/de not_active IP Right Cessation
- 1982-09-10 DE DE823248957T patent/DE3248957T1/de active Granted
- 1982-09-10 WO PCT/JP1982/000363 patent/WO1983000865A1/ja not_active Ceased
- 1982-09-13 FR FR8215454A patent/FR2512820B1/fr not_active Expired
1983
- 1983-04-26 SE SE8302352A patent/SE444681B/sv not_active IP Right Cessation
- 1983-04-27 FI FI831431A patent/FI68232C/fi not_active IP Right Cessation
- 1983-05-10 NO NO831653A patent/NO831653L/no unknown
- 1983-05-11 DK DK211283A patent/DK164403C/da not_active IP Right Cessation
- 1983-05-13 ES ES522386A patent/ES8407033A1/es not_active Expired
1984
- 1984-05-21 US US06/612,322 patent/US4552969A/en not_active Expired - Fee Related
- 1984-05-21 US US06/612,323 patent/US4558125A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK211283D0 (da)	1983-05-11
IT1196423B (it)	1988-11-16
ES515655A0 (es)	1983-09-16
GB2115815B (en)	1985-06-19
ES522386A0 (es)	1984-08-16
DE3248957T1 (de)	1983-10-20
CA1169860A (en)	1984-06-26
DK164403C (da)	1992-11-16
IT8223146A0 (it)	1982-09-07
SE444681B (sv)	1986-04-28
FR2512820B1 (fr)	1986-11-21
NO831653L (no)	1983-05-10
FI68232C (fi)	1985-08-12
GB8311096D0 (en)	1983-05-25
FI68232B (fi)	1985-04-30
AT379592B (de)	1986-01-27
ATA904882A (de)	1985-06-15
AU8902682A (en)	1983-03-28
ES8407033A1 (es)	1984-08-16
US4558125A (en)	1985-12-10
NL8220310A (nl)	1983-08-01
BE894358A (fr)	1983-01-03
SE8302352L (sv)	1983-04-26
DE3248957C2 (da)	1989-09-21
GB2115815A (en)	1983-09-14
US4552969A (en)	1985-11-12
JPS5846079A (ja)	1983-03-17
US4479949A (en)	1984-10-30
DK164403B (da)	1992-06-22
FI831431A0 (fi)	1983-04-27
FI831431L (fi)	1983-04-27
ES8308552A1 (es)	1983-09-16
AU541223B2 (en)	1984-12-20
FR2512820A1 (fr)	1983-03-18
CH654001A5 (de)	1986-01-31
WO1983000865A1 (fr)	1983-03-17
SE8302352D0 (sv)	1983-04-26

Legal Events

Date	Code	Title	Description
1998-05-11	PBP	Patent lapsed

Publication	Publication Date	Title
SE7907121L (sv)	1981-02-28	Ftalimidinderivat
NO820264L (no)	1982-08-03	Fremgangsmaate for fremstilling av 2-penemforbindelser
SE8101409L (sv)	1981-09-07	Karbostyrilderivat och forfarande for framstellning derav
IT1171880B (it)	1987-06-10	Derivati di 2-ammino-3-acilammino-6-benzilammino-piridina aventi azione antiepilettica e procedimento per la loro produzione
ATE24001T1 (de)	1986-12-15	Substituierte 1-hydroxyethyl-triazolyl-derivate.
FI823923A0 (fi)	1982-11-16	Antifibrinolytiskt aktiva foereningar
SE7602144L (sv)	1976-09-13	Kvaternera imidazoliumforeningar
DE3266708D1 (en)	1985-11-07	Pyridazinone derivatives, process for their preparation and their use as fungicides
ES8308552A1 (es)	1983-09-16	Un procedimiento para la preparacion de derivados de benzotiazolina.
YU310580A (en)	1983-04-30	Process for obtaining new benzothiazole derivatives
ES8203870A1 (es)	1982-04-01	Procedimiento para preparar difenilbutil-1-acilpiperazinas
FI810145L (fi)	1981-07-23	Nya substituerade 1,8-dihydroxi-9-(10h)antracenoner foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel
DK392579A (da)	1980-03-22	Fremgangsmaade til fremstilling af 4,5-methano-bufadienolid-rhamnosider
DE3363575D1 (en)	1986-06-26	Furyloxazolylacetic acid derivatives, process for preparing same and pharmaceutical compositions containing same
NO834566L (no)	1984-06-14	Fremgangsmaate ved fremstilling av imidazolderivater
NO870077L (no)	1987-07-10	Nye tyroninderivater.
ATE17851T1 (de)	1986-02-15	Imidazolylkarbonsaeure, deren derivate und herstellung.
DE3168178D1 (en)	1985-02-21	2-(n-aryl-n-1,2,3-thiadiazolyl-carbonyl)-aminobutyrolactones, their preparation, fungicides containing them and their use as fungicides
DE3362036D1 (en)	1986-03-13	Ketene-o,o-acetates and process for their preparation
GB1124272A (en)	1968-08-21	Novel 2 - amino - 2,3 - dihydro - 3,3 - polymethylene - 5 - benzofuranols and derivatives thereof
DE3270999D1 (de)	1986-06-12	N-substituted-tetrahydroisophthalimide derivatives
SE8701524D0 (sv)	1987-04-10	Nya sulfonamider och deras framstellningsforfarande
JPS51133243A (en)	1976-11-18	Process for preparing phthalamic acid ester derivatives
ES451291A1 (es)	1977-10-01	Un procedimiento para la preparacion de derivados de tieno- tiacina.
CH653840GA3 (en)	1986-01-31	Process for protecting keratin-containing materials from attack by keratin-eating insects and 5-phenylcarbamoylbarbituric acid compounds