DK2365975T3 - Imidazopyridinderivativer, som inhiberer secernering af mavesyre - Google Patents

Imidazopyridinderivativer, som inhiberer secernering af mavesyre

Info

Publication number
DK2365975T3
DK2365975T3 DK09748823.3T DK09748823T DK2365975T3 DK 2365975 T3 DK2365975 T3 DK 2365975T3 DK 09748823 T DK09748823 T DK 09748823T DK 2365975 T3 DK2365975 T3 DK 2365975T3
Authority
DK
Denmark
Prior art keywords
gastric acid
acid secretion
imidazopyridine derivatives
inhibit gastric
inhibit
Prior art date
Application number
DK09748823.3T
Other languages
English (en)
Inventor
Mikael Dahlstroem
Original Assignee
Mikael Dahlstroem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mikael Dahlstroem filed Critical Mikael Dahlstroem
Application granted granted Critical
Publication of DK2365975T3 publication Critical patent/DK2365975T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK09748823.3T 2008-12-03 2009-10-27 Imidazopyridinderivativer, som inhiberer secernering af mavesyre DK2365975T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20086158A FI20086158A0 (fi) 2008-12-03 2008-12-03 Imidatsopyridiinijohdannaiset
PCT/FI2009/050861 WO2010063876A1 (en) 2008-12-03 2009-10-27 Imidazopyridine derivatives which inhibit the secretion of gastric acid

Publications (1)

Publication Number Publication Date
DK2365975T3 true DK2365975T3 (da) 2013-06-10

Family

ID=40240558

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09748823.3T DK2365975T3 (da) 2008-12-03 2009-10-27 Imidazopyridinderivativer, som inhiberer secernering af mavesyre

Country Status (22)

Country Link
US (2) US8669269B2 (da)
EP (1) EP2365975B1 (da)
JP (2) JP5702295B2 (da)
KR (1) KR101742328B1 (da)
CN (1) CN102239167B (da)
AU (1) AU2009324007B2 (da)
BR (1) BRPI0916475A2 (da)
CA (1) CA2744647C (da)
CY (1) CY1114038T1 (da)
DK (1) DK2365975T3 (da)
ES (1) ES2415894T3 (da)
FI (1) FI20086158A0 (da)
HR (1) HRP20130476T1 (da)
IL (1) IL213242A (da)
MX (1) MX2011005769A (da)
PL (1) PL2365975T3 (da)
PT (1) PT2365975E (da)
RU (1) RU2509771C2 (da)
SI (1) SI2365975T1 (da)
SM (1) SMT201300066B (da)
WO (1) WO2010063876A1 (da)
ZA (1) ZA201104838B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
ES2949232T3 (es) * 2019-11-04 2023-09-26 Cinclus Pharma Holding Ab Publ Formulación Oral de X842
JP2024530045A (ja) * 2021-11-05 2024-08-14 シンクルス・ファーマ・ホールディング・アクチエボラグ リナプラザングルレート塩酸塩の多形
JP2024542115A (ja) 2021-11-05 2024-11-13 シンクルス・ファーマ・ホールディング・アクチエボラグ リナプラザングルレートのメシラート塩の多形体
WO2023184282A1 (en) 2022-03-30 2023-10-05 Guizhou Sinorda Biomedicine Co., Ltd X842 formulation
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
KR102827602B1 (ko) * 2022-09-05 2025-07-02 연세대학교 산학협력단 Scl26a9 억제제를 유효성분으로 포함하는 위산 분비 억제용 약학 조성물
KR20250130654A (ko) 2023-01-11 2025-09-02 싱클루스 파마 홀딩 에이비 (피유비엘) 리나프라잔 글루레이트의 말레산 염의 다형체
KR20250132529A (ko) 2023-01-11 2025-09-04 싱클루스 파마 홀딩 에이비 (피유비엘) 리나프라잔 글루레이트의 하이드로브로마이드 염의 다형체
TW202432120A (zh) * 2023-02-01 2024-08-16 韓商安康尼克治療有限公司 注射用組合物、包含其之醫藥調配物以及製備該組合物之方法
CR20250351A (es) * 2023-02-01 2025-10-13 Jeil Pharmaceutical Co Ltd Formulación farmacéutica, método de preparación para la misma y composición de tableta
KR20260019468A (ko) * 2023-05-08 2026-02-10 싱클루스 파마 홀딩 에이비 (피유비엘) 위식도 역류 질환(gerd) 치료를 위한 리나프라잔 글루레이트
WO2026032974A1 (en) 2024-08-05 2026-02-12 Cinclus Pharma Holding AB (publ) Formulation of linaprazan glurate

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA81219B (en) 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
SE0102808D0 (sv) 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
SE0301905D0 (sv) 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
WO2005041961A1 (en) * 2003-11-03 2005-05-12 Astrazeneca Ab Imidazo [1,2-a] pyridine derivatives for the treatment of silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
PE20061110A1 (es) 2005-03-24 2006-10-20 Glaxo Group Ltd Derivados de imidazopiridina como antagonistas de la bomba de acido (apa)
EP1934215A1 (en) 2005-09-22 2008-06-25 Nycomed GmbH Isotopically substituted imidazopyridine derivatives for the treatment of gastrointestinal disorders
FI20086158A0 (fi) * 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset

Also Published As

Publication number Publication date
KR20110096146A (ko) 2011-08-29
AU2009324007A1 (en) 2011-07-07
US20140235666A1 (en) 2014-08-21
JP2015063548A (ja) 2015-04-09
RU2509771C2 (ru) 2014-03-20
ES2415894T3 (es) 2013-07-29
ZA201104838B (en) 2012-03-28
JP5702295B2 (ja) 2015-04-15
SI2365975T1 (sl) 2013-08-30
PT2365975E (pt) 2013-06-20
US8669269B2 (en) 2014-03-11
CN102239167B (zh) 2015-06-17
CA2744647A1 (en) 2010-06-10
MX2011005769A (es) 2011-09-15
PL2365975T3 (pl) 2013-08-30
US8993589B2 (en) 2015-03-31
HK1164277A1 (en) 2012-09-21
RU2011124169A (ru) 2013-01-10
SMT201300066B (it) 2013-09-06
BRPI0916475A2 (pt) 2019-09-10
KR101742328B1 (ko) 2017-06-01
AU2009324007B2 (en) 2014-05-08
EP2365975A1 (en) 2011-09-21
HRP20130476T1 (hr) 2013-08-31
WO2010063876A1 (en) 2010-06-10
IL213242A0 (en) 2011-07-31
US20110237619A1 (en) 2011-09-29
CN102239167A (zh) 2011-11-09
EP2365975B1 (en) 2013-03-13
IL213242A (en) 2014-01-30
JP2012510505A (ja) 2012-05-10
CY1114038T1 (el) 2016-07-27
CA2744647C (en) 2018-01-09
FI20086158A0 (fi) 2008-12-03

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