DK240386A - Morphinanderivater - Google Patents

Morphinanderivater Download PDF

Info

Publication number: DK240386A
Authority: DK; Denmark
Prior art keywords: morphinan
Prior art date: 1985-05-23

Application number

DK240386A

Other languages

Danish (da)

English (en)

Other versions

DK240386D0 (da

Inventor

Laszlo Revesz

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-23

Filing date

1986-05-22

Publication date

1986-11-24

1986-05-22 Application filed by Sandoz Ag filed Critical Sandoz Ag

1986-05-22 Publication of DK240386D0 publication Critical patent/DK240386D0/da

1986-11-24 Publication of DK240386A publication Critical patent/DK240386A/da

Links

INAXVFBXDYWQFN-XHSDSOJGSA-N morphinan Chemical compound C1C2=CC=CC=C2[C@]23CCCC[C@H]3[C@@H]1NCC2 INAXVFBXDYWQFN-XHSDSOJGSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Addiction (AREA)
Psychiatry (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK240386A 1985-05-23 1986-05-22 Morphinanderivater DK240386A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3518525		1985-05-23

Publications (2)

Publication Number	Publication Date
DK240386D0 DK240386D0 (da)	1986-05-22
DK240386A true DK240386A (da)	1986-11-24

Family

ID=6271435

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK240386A DK240386A (da)	1985-05-23	1986-05-22	Morphinanderivater

Country Status (18)

Country	Link
JP (1)	JPS61271275A (fr)
AU (1)	AU594954B2 (fr)
BE (1)	BE904796A (fr)
DK (1)	DK240386A (fr)
ES (1)	ES8802318A1 (fr)
FI (1)	FI862124L (fr)
FR (1)	FR2582309B1 (fr)
GB (1)	GB2175898B (fr)
GR (1)	GR861318B (fr)
HU (1)	HU196376B (fr)
IL (1)	IL78872A0 (fr)
IT (1)	IT1203791B (fr)
LU (1)	LU86435A1 (fr)
NL (1)	NL8601188A (fr)
NZ (1)	NZ216250A (fr)
PH (1)	PH23341A (fr)
SE (1)	SE8602308L (fr)
ZA (1)	ZA863873B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4857533A (en) *	1988-12-15	1989-08-15	Baker Cummins Pharmaceuticals, Inc.	Method of treatment for autoimmune diseases
US4863928A (en) *	1989-01-04	1989-09-05	Baker Cummins Pharmaceuticals, Inc.	Method of treatment for arthritic and inflammatory diseases
US4923875A (en) *	1989-07-10	1990-05-08	Baker Cummins Pharmaceuticals, Inc.	Method for treatment of mast cell-mediated dermatologic disorders
JP2906654B2 (ja) *	1989-11-28	1999-06-21	東レ株式会社	免疫抑制剤及びその製造方法
US5057322A (en) *	1990-08-10	1991-10-15	Baker Cummins Dermatologicals, Inc.	Method of treating mast cell disease
US6323212B1 (en)	1992-01-23	2001-11-27	Toray Industries, Inc.	Morphinan derivative and its pharmaceutical applications
EP0661283B1 (fr) *	1993-07-19	1998-10-21	Toray Industries, Inc.	Agent de protection de cellules cerebrales
EP0663401B1 (fr)	1993-07-23	2000-06-07	Toray Industries, Inc.	Derive de morphinane et application medicale
ES2188888T3 (es) *	1996-01-10	2003-07-01	Glaxosmithkline Spa	Derivados morfinoides 8ii) con condensados con heterociclos.
ATE359076T1 (de) *	1996-11-25	2007-05-15	Toray Industries	Mittel gegen juckreiz
WO1999005146A1 (fr) *	1997-07-25	1999-02-04	Toray Industries, Inc.	Remedes contre l'hyponatremie
US7923454B2 (en)	2002-05-17	2011-04-12	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US7501433B2 (en)	2002-05-17	2009-03-10	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
AU2003234621A1 (en)	2002-05-17	2003-12-02	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
JP4957489B2 (ja) *	2002-10-09	2012-06-20	東レ株式会社	含窒素環状置換基を有するモルヒナン誘導体またはその薬理学的に許容される酸付加塩を含有する医薬
US8017622B2 (en)	2003-05-16	2011-09-13	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
EP2252150B1 (fr) *	2008-02-14	2018-04-11	Alkermes, Inc.	Composés opioïdes sélectifs
ES2631197T3 (es) *	2012-12-14	2017-08-29	Purdue Pharma Lp	Análogos de piridonamorfinano y actividad biológica sobre los receptores opiodes
WO2014091297A1 (fr) *	2012-12-14	2014-06-19	Purdue Pharma L.P.	Morphinanes spirocycliques et leur utilisation
AR096851A1 (es) *	2013-07-11	2016-02-03	H Lundbeck As	Sales que no forman hidratos ni solvatos de nalmefeno
CA2951697A1 (fr) *	2014-06-13	2015-12-17	Purdue Pharma L.P.	Derives d'azamophinan et leur utilisation

1986
- 1986-05-09 HU HU861934A patent/HU196376B/hu not_active IP Right Cessation
- 1986-05-12 NL NL8601188A patent/NL8601188A/nl not_active Application Discontinuation
- 1986-05-19 GB GB8612159A patent/GB2175898B/en not_active Expired
- 1986-05-19 PH PH33785A patent/PH23341A/en unknown
- 1986-05-21 IL IL78872A patent/IL78872A0/xx unknown
- 1986-05-21 BE BE1/011493A patent/BE904796A/fr not_active IP Right Cessation
- 1986-05-21 GR GR861318A patent/GR861318B/el unknown
- 1986-05-21 NZ NZ216250A patent/NZ216250A/en unknown
- 1986-05-21 FI FI862124A patent/FI862124L/fi not_active Application Discontinuation
- 1986-05-21 ES ES555200A patent/ES8802318A1/es not_active Expired
- 1986-05-21 AU AU57637/86A patent/AU594954B2/en not_active Expired - Fee Related
- 1986-05-21 SE SE8602308A patent/SE8602308L/xx not_active Application Discontinuation
- 1986-05-22 JP JP61118984A patent/JPS61271275A/ja active Pending
- 1986-05-22 LU LU86435A patent/LU86435A1/fr unknown
- 1986-05-22 DK DK240386A patent/DK240386A/da not_active Application Discontinuation
- 1986-05-23 FR FR8607367A patent/FR2582309B1/fr not_active Expired
- 1986-05-23 IT IT48050/86A patent/IT1203791B/it active
- 1986-05-23 ZA ZA863873A patent/ZA863873B/xx unknown

Also Published As

Publication number	Publication date
JPS61271275A (ja)	1986-12-01
FI862124A7 (fi)	1986-11-24
NL8601188A (nl)	1986-12-16
BE904796A (fr)	1986-11-21
DK240386D0 (da)	1986-05-22
SE8602308D0 (sv)	1986-05-21
GB8612159D0 (en)	1986-06-25
LU86435A1 (fr)	1986-12-05
FI862124A0 (fi)	1986-05-21
IT8648050A0 (it)	1986-05-23
ZA863873B (en)	1988-01-27
GB2175898A (en)	1986-12-10
HU196376B (en)	1988-11-28
GB2175898B (en)	1989-07-05
FI862124L (fi)	1986-11-24
AU594954B2 (en)	1990-03-22
IT1203791B (it)	1989-02-23
IL78872A0 (en)	1986-09-30
ES8802318A1 (es)	1988-05-01
HUT41737A (en)	1987-05-28
PH23341A (en)	1989-07-14
ES555200A0 (es)	1988-05-01
SE8602308L (sv)	1986-11-24
FR2582309A1 (fr)	1986-11-28
AU5763786A (en)	1986-11-27
NZ216250A (en)	1990-04-26
FR2582309B1 (fr)	1989-08-18
GR861318B (en)	1986-09-19

Legal Events

Date	Code	Title	Description
1991-01-21	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
DK240386D0 (da)	1986-05-22	Morphinanderivater
ATA155686A (de)	1993-04-15	Giesspfannenkopf
AT386920B (de)	1988-11-10	Maishaecksler
SE8600436D0 (sv)	1986-01-31	Sprengladdning
ATA122686A (de)	1989-12-15	Kettenschloss
BR8501248A (pt)	1986-10-29	Sulcador pontiagudo
ATA257585A (de)	1988-04-15	Ru-deruebungsgeraet
ATA173385A (de)	1987-03-15	Stiegenlift
BR6500481U (pt)	1986-11-25	Omeleteira
BR8505870A (pt)	1986-02-04	Comedouro
BR6501483U (pt)	1987-05-05	Expremedor
BR6500776U (pt)	1987-01-13	Miniploter
BR6501484U (pt)	1987-02-17	Vasilhame
BR6502051U (pt)	1986-02-25	Mult-sinalizador
BR6500257U (pt)	1986-10-14	Chaveiro-calendario-utilidades
BR8501720A (pt)	1985-09-17	Semeadeira-adubadeira
BR6500483U (pt)	1986-11-25	Dialisor
BR6501731U (pt)	1987-06-16	Cine-livro
BR6500027U (pt)	1985-06-04	Conzeiro
BR6501802U (pt)	1987-06-16	Mini-luminaria
BR6501183U (pt)	1987-03-31	Bonequinho
BR8503788A (pt)	1987-03-17	Semeadeira-adubadeira
BR6500852U (pt)	1987-02-10	Churrasqueira-espeto
BR6500176U (pt)	1986-09-16	Pulverizador-cobridor
BR8503827A (pt)	1985-10-22	Patrulhometro