SE8602308L - Morfinanderivat - Google Patents
MorfinanderivatInfo
- Publication number
- SE8602308L SE8602308L SE8602308A SE8602308A SE8602308L SE 8602308 L SE8602308 L SE 8602308L SE 8602308 A SE8602308 A SE 8602308A SE 8602308 A SE8602308 A SE 8602308A SE 8602308 L SE8602308 L SE 8602308L
- Authority
- SE
- Sweden
- Prior art keywords
- denotes
- atoms
- hydrogen
- alkyl
- phenyl
- Prior art date
Links
- INAXVFBXDYWQFN-XHSDSOJGSA-N morphinan Chemical compound C1C2=CC=CC=C2[C@]23CCCC[C@H]3[C@@H]1NCC2 INAXVFBXDYWQFN-XHSDSOJGSA-N 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 9
- 239000001257 hydrogen Substances 0.000 abstract 9
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 150000002431 hydrogen Chemical class 0.000 abstract 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 2
- 239000012458 free base Substances 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 150000003839 salts Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000006704 (C5-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000003402 opiate agonist Substances 0.000 abstract 1
- 239000003401 opiate antagonist Substances 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3518525 | 1985-05-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8602308D0 SE8602308D0 (sv) | 1986-05-21 |
| SE8602308L true SE8602308L (sv) | 1986-11-24 |
Family
ID=6271435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8602308A SE8602308L (sv) | 1985-05-23 | 1986-05-21 | Morfinanderivat |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS61271275A (fr) |
| AU (1) | AU594954B2 (fr) |
| BE (1) | BE904796A (fr) |
| DK (1) | DK240386A (fr) |
| ES (1) | ES8802318A1 (fr) |
| FI (1) | FI862124L (fr) |
| FR (1) | FR2582309B1 (fr) |
| GB (1) | GB2175898B (fr) |
| GR (1) | GR861318B (fr) |
| HU (1) | HU196376B (fr) |
| IL (1) | IL78872A0 (fr) |
| IT (1) | IT1203791B (fr) |
| LU (1) | LU86435A1 (fr) |
| NL (1) | NL8601188A (fr) |
| NZ (1) | NZ216250A (fr) |
| PH (1) | PH23341A (fr) |
| SE (1) | SE8602308L (fr) |
| ZA (1) | ZA863873B (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4857533A (en) * | 1988-12-15 | 1989-08-15 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for autoimmune diseases |
| US4863928A (en) * | 1989-01-04 | 1989-09-05 | Baker Cummins Pharmaceuticals, Inc. | Method of treatment for arthritic and inflammatory diseases |
| US4923875A (en) * | 1989-07-10 | 1990-05-08 | Baker Cummins Pharmaceuticals, Inc. | Method for treatment of mast cell-mediated dermatologic disorders |
| JP2906654B2 (ja) * | 1989-11-28 | 1999-06-21 | 東レ株式会社 | 免疫抑制剤及びその製造方法 |
| US5057322A (en) * | 1990-08-10 | 1991-10-15 | Baker Cummins Dermatologicals, Inc. | Method of treating mast cell disease |
| JP2525552B2 (ja) * | 1992-01-23 | 1996-08-21 | 東レ株式会社 | モルヒナン誘導体および医薬用途 |
| KR100341950B1 (ko) * | 1993-07-19 | 2002-11-29 | 도레이 가부시끼가이샤 | 뇌세포보호제 |
| NZ268969A (en) * | 1993-07-23 | 1997-06-24 | Toray Industries | Morphinan derivatives and pharmaceutical compositions |
| HUP9900974A3 (en) | 1996-01-10 | 2000-09-28 | Smithkline Beecham Spa | Heterocycle-condensed morphinoid derivatives, process for the preparation thereof, their use and pharmaceutical compositions containing them |
| CN1535687A (zh) * | 1996-11-25 | 2004-10-13 | ������������ʽ���� | 止痒药物 |
| WO1999005146A1 (fr) * | 1997-07-25 | 1999-02-04 | Toray Industries, Inc. | Remedes contre l'hyponatremie |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| WO2003097608A2 (fr) | 2002-05-17 | 2003-11-27 | Jenken Biosciences, Inc. | Composes opioides et de type opioide et leurs utilisations |
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| JP4957489B2 (ja) * | 2002-10-09 | 2012-06-20 | 東レ株式会社 | 含窒素環状置換基を有するモルヒナン誘導体またはその薬理学的に許容される酸付加塩を含有する医薬 |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| JP2011512360A (ja) * | 2008-02-14 | 2011-04-21 | アルカーメス，インコーポレイテッド | 選択的オピオイド化合物 |
| ES2631197T3 (es) * | 2012-12-14 | 2017-08-29 | Purdue Pharma Lp | Análogos de piridonamorfinano y actividad biológica sobre los receptores opiodes |
| EP2931726B1 (fr) * | 2012-12-14 | 2017-01-25 | Purdue Pharma LP | Morphinanes spirocycliques et leur utilisation |
| AR096851A1 (es) * | 2013-07-11 | 2016-02-03 | H Lundbeck As | Sales que no forman hidratos ni solvatos de nalmefeno |
| CA2951697A1 (fr) * | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Derives d'azamophinan et leur utilisation |
-
1986
- 1986-05-09 HU HU861934A patent/HU196376B/hu not_active IP Right Cessation
- 1986-05-12 NL NL8601188A patent/NL8601188A/nl not_active Application Discontinuation
- 1986-05-19 PH PH33785A patent/PH23341A/en unknown
- 1986-05-19 GB GB8612159A patent/GB2175898B/en not_active Expired
- 1986-05-21 FI FI862124A patent/FI862124L/fi not_active Application Discontinuation
- 1986-05-21 BE BE1/011493A patent/BE904796A/fr not_active IP Right Cessation
- 1986-05-21 NZ NZ216250A patent/NZ216250A/en unknown
- 1986-05-21 GR GR861318A patent/GR861318B/el unknown
- 1986-05-21 IL IL78872A patent/IL78872A0/xx unknown
- 1986-05-21 SE SE8602308A patent/SE8602308L/xx not_active Application Discontinuation
- 1986-05-21 AU AU57637/86A patent/AU594954B2/en not_active Expired - Fee Related
- 1986-05-21 ES ES555200A patent/ES8802318A1/es not_active Expired
- 1986-05-22 LU LU86435A patent/LU86435A1/fr unknown
- 1986-05-22 DK DK240386A patent/DK240386A/da not_active Application Discontinuation
- 1986-05-22 JP JP61118984A patent/JPS61271275A/ja active Pending
- 1986-05-23 ZA ZA863873A patent/ZA863873B/xx unknown
- 1986-05-23 IT IT48050/86A patent/IT1203791B/it active
- 1986-05-23 FR FR8607367A patent/FR2582309B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI862124A7 (fi) | 1986-11-24 |
| NZ216250A (en) | 1990-04-26 |
| HUT41737A (en) | 1987-05-28 |
| GB2175898A (en) | 1986-12-10 |
| ES8802318A1 (es) | 1988-05-01 |
| GB2175898B (en) | 1989-07-05 |
| FI862124L (fi) | 1986-11-24 |
| FI862124A0 (fi) | 1986-05-21 |
| NL8601188A (nl) | 1986-12-16 |
| AU5763786A (en) | 1986-11-27 |
| GB8612159D0 (en) | 1986-06-25 |
| DK240386D0 (da) | 1986-05-22 |
| BE904796A (fr) | 1986-11-21 |
| GR861318B (en) | 1986-09-19 |
| AU594954B2 (en) | 1990-03-22 |
| IT1203791B (it) | 1989-02-23 |
| LU86435A1 (fr) | 1986-12-05 |
| FR2582309A1 (fr) | 1986-11-28 |
| PH23341A (en) | 1989-07-14 |
| IT8648050A0 (it) | 1986-05-23 |
| ZA863873B (en) | 1988-01-27 |
| SE8602308D0 (sv) | 1986-05-21 |
| FR2582309B1 (fr) | 1989-08-18 |
| DK240386A (da) | 1986-11-24 |
| IL78872A0 (en) | 1986-09-30 |
| ES555200A0 (es) | 1988-05-01 |
| JPS61271275A (ja) | 1986-12-01 |
| HU196376B (en) | 1988-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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