DK3539666T3 - Indretning til ekstrem pcr - Google Patents
Indretning til ekstrem pcr Download PDFInfo
- Publication number
- DK3539666T3 DK3539666T3 DK19166256.8T DK19166256T DK3539666T3 DK 3539666 T3 DK3539666 T3 DK 3539666T3 DK 19166256 T DK19166256 T DK 19166256T DK 3539666 T3 DK3539666 T3 DK 3539666T3
- Authority
- DK
- Denmark
- Prior art keywords
- extreme pcr
- pcr
- extreme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/02—Water baths; Sand baths; Air baths
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
- B01L7/525—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones
- B01L7/5255—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples with physical movement of samples between temperature zones by moving sample containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Clinical Laboratory Science (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Prostheses (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261651161P | 2012-05-24 | 2012-05-24 | |
| US201361811145P | 2013-04-12 | 2013-04-12 | |
| EP13793389.1A EP2855692B1 (en) | 2012-05-24 | 2013-05-23 | Extreme pcr |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3539666T3 true DK3539666T3 (da) | 2021-09-13 |
Family
ID=49624526
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13793389.1T DK2855692T3 (da) | 2012-05-24 | 2013-05-23 | Ekstrem pcr |
| DK19166256.8T DK3539666T3 (da) | 2012-05-24 | 2013-05-23 | Indretning til ekstrem pcr |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13793389.1T DK2855692T3 (da) | 2012-05-24 | 2013-05-23 | Ekstrem pcr |
Country Status (12)
| Country | Link |
|---|---|
| US (6) | US9932634B2 (da) |
| EP (5) | EP2855692B1 (da) |
| JP (3) | JP6316802B2 (da) |
| CN (2) | CN108251271A (da) |
| AU (1) | AU2013266246B2 (da) |
| CA (1) | CA2873991C (da) |
| DK (2) | DK2855692T3 (da) |
| ES (3) | ES3011358T3 (da) |
| PL (2) | PL3957748T3 (da) |
| PT (2) | PT2855692T (da) |
| SG (3) | SG11201407427WA (da) |
| WO (1) | WO2013177429A2 (da) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2855692B1 (en) | 2012-05-24 | 2019-07-24 | University of Utah Research Foundation | Extreme pcr |
| WO2015069743A1 (en) * | 2013-11-05 | 2015-05-14 | Biofire Diagnostics, Llc | Induction pcr |
| CN106661600B (zh) * | 2014-07-16 | 2021-04-06 | 唐恩生物科技股份有限公司 | 用于扩增核酸样品的等温方法 |
| US11559801B2 (en) | 2014-11-03 | 2023-01-24 | Tangen Biosciences, Inc. | Apparatus and method for cell, spore, or virus capture and disruption |
| RU2666910C1 (ru) * | 2014-11-07 | 2018-09-13 | ДжНА БИОСОЛЮШЕНЗ ГМБХ | Способ суперамплификации с пцр |
| TW201641687A (zh) * | 2014-12-31 | 2016-12-01 | 卡尤迪生物科技（北京）有限公司 | 用于進行化學反應的設備和方法 |
| WO2016106717A1 (en) * | 2014-12-31 | 2016-07-07 | Coyote Bioscience Co., Ltd. | Apparatus and methods for conducting chemical reactions |
| WO2016196827A1 (en) | 2015-06-02 | 2016-12-08 | Biofire Defense, Llc | Sample to sequence |
| CN115181781A (zh) | 2015-11-02 | 2022-10-14 | 拜奥法尔诊断有限责任公司 | 困难样品类型的样品制备 |
| DK3337615T3 (da) * | 2015-11-05 | 2022-05-09 | Univ Utah Res Found | Ekstrem pcr via revers transkription |
| CN109642198A (zh) * | 2016-02-10 | 2019-04-16 | 卡尤迪生物科技（北京）有限公司 | 用于分析核酸的方法和系统 |
| US10875026B2 (en) | 2016-02-22 | 2020-12-29 | Biofire Defense, Llc | Devices and methods for rapid PCR |
| CN109963948B (zh) | 2016-03-24 | 2023-01-24 | 拜奥法尔诊断有限责任公司 | 用于定量扩增的方法 |
| US11786906B2 (en) | 2016-04-15 | 2023-10-17 | Biofire Defense, Llc | Resistive heaters and anisotropic thermal transfer |
| SG10201700260XA (en) * | 2016-06-10 | 2018-01-30 | Star Array Pte Ltd | Rapid thermal cycling for sample analyses and processing |
| WO2017213586A1 (en) * | 2016-06-10 | 2017-12-14 | Star Array Pte Ltd | Rapid thermal cycling for sample analyses and processing |
| US11090652B2 (en) | 2016-07-28 | 2021-08-17 | Biofire Defense, Llc | Self-contained nucleic acid processing |
| JP2018023360A (ja) * | 2016-07-29 | 2018-02-15 | セイコーエプソン株式会社 | 核酸増幅反応方法、試薬、および試薬の使用方法 |
| US10434515B2 (en) | 2016-10-03 | 2019-10-08 | University Of Utah Research Foundation | Thermal gradient plug flow microfluidic devices for extreme PCR |
| EP3562592B1 (en) * | 2016-12-29 | 2025-04-23 | BioFire Defense, LLC | Fast pcr with molecular crowding |
| US11192103B2 (en) | 2017-05-04 | 2021-12-07 | University Of Utah Research Foundation | Micro-fluidic device for rapid PCR |
| KR102205804B1 (ko) | 2017-05-24 | 2021-01-22 | 바이오파이어 디펜스, 엘엘씨 | 사용 시점에서 어레이의 배기를 위한 시스템 및 방법 |
| CN107502657A (zh) * | 2017-07-12 | 2017-12-22 | 浙江大学 | 一种极速pcr（聚合酶链式反应）扩增和终点检测方法 |
| US11398296B2 (en) | 2017-07-21 | 2022-07-26 | Biofire Diagnostics, Llc | Detection using concurrent melting curves |
| CN107930716B (zh) * | 2017-12-31 | 2023-05-09 | 江苏科泰检测技术服务有限公司 | 检测室用自动旋转式梯度恒温水浴锅及其使用方法 |
| CN108251501A (zh) * | 2018-02-08 | 2018-07-06 | 中国农业大学 | 一种转基因作物双重基因的可视化定量筛查新方法 |
| JP7590954B2 (ja) | 2018-04-20 | 2024-11-27 | バイオファイア・ダイアグノスティクス，リミテッド・ライアビリティ・カンパニー | シーケンシングデータの正規化および定量化のための方法 |
| WO2019236978A1 (en) | 2018-06-07 | 2019-12-12 | Biofire Diagnostics, Llc | Rapid thermocycling methods |
| KR102116118B1 (ko) * | 2018-07-18 | 2020-05-27 | 주식회사 케이티앤지 | 에어로졸 생성장치의 히터의 온도를 구간별로 제어하는 방법 및 그 방법을 구현하기 위한 에어로졸 생성장치 |
| GB201812192D0 (en) | 2018-07-26 | 2018-09-12 | Ttp Plc | Variable temperature reactor, heater and control circuit for the same |
| CN108752418B (zh) * | 2018-08-08 | 2024-01-30 | 湖南科技学院 | 一种多通道多肽合成反应装置及其操作方法 |
| US12390812B2 (en) | 2018-12-19 | 2025-08-19 | Nuclein, Llc | Apparatus and methods for molecular diagnostics |
| CN110114475B (zh) * | 2018-12-20 | 2021-06-18 | 广州市华南医学研究中心 | 一种极速核酸扩增的方法及其设备和应用 |
| EP3898230A4 (en) | 2018-12-21 | 2022-09-28 | BioFire Diagnostics, LLC | APPARATUS, METHODS AND SYSTEMS FOR IN-SITU SEALING REACTION VESSELS |
| US20220064707A1 (en) * | 2019-01-17 | 2022-03-03 | Northwestern University | Rapid reverse transcription quantitative polymerase chain reaction |
| US10865441B2 (en) | 2019-03-13 | 2020-12-15 | Abclonal Science, Inc. | Mutant Taq polymerase for faster amplification |
| CN110387325A (zh) * | 2019-08-13 | 2019-10-29 | 广州市华南医学研究中心 | 一种极速pcr反应检测装置及检测方法 |
| CN111154844B (zh) * | 2020-04-07 | 2020-09-04 | 中国农业大学 | 一种基于超速pcr与功能核酸的可视化检测方法 |
| CN111974480A (zh) * | 2020-09-02 | 2020-11-24 | 杭州潘达科技有限公司 | 一种稳定效果好的具有多隔层的恒温水浴锅 |
| JP7641487B2 (ja) * | 2020-11-27 | 2025-03-07 | キュアバック マニュファクチャリング ゲーエムベーハー | キャピラリーポリメラーゼ連鎖反応によってｄｎａ産物を調製するためのデバイス |
| CN113967487B (zh) * | 2021-10-11 | 2022-12-02 | 华中科技大学 | 一种喷嘴、液滴光热操控系统及其应用 |
| GB202115637D0 (en) | 2021-11-01 | 2021-12-15 | Anglia Ruskin Univ Higher Education Corporation | Nucleic acid amplification method |
| CN114214465A (zh) * | 2022-01-26 | 2022-03-22 | 山东仕达思生物产业有限公司 | 一种缩短新型冠状病毒检测时间的引物、探针、试剂盒及检测方法 |
| KR102821115B1 (ko) * | 2022-10-04 | 2025-06-16 | 한국광기술원 | Pcr 유전자 증폭 장치 |
| EP4622974A1 (en) | 2022-11-22 | 2025-10-01 | bioMérieux | New nucleic acid binding compounds and uses |
| JP2026511043A (ja) * | 2023-03-20 | 2026-04-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | ポリメラーゼ連鎖反応（ｐｃｒ）を用いた核酸を増幅するための方法およびシステム |
| WO2025003077A1 (fr) * | 2023-06-28 | 2025-01-02 | bioMérieux | Fabrication de kits d'amplification en chaine par polymerase optimisant une phase de denaturation de l'amplification |
| KR20260032911A (ko) * | 2023-06-28 | 2026-03-10 | 비오메리으 | 증폭 혼성화 단계를 최적화하는 중합효소 연쇄 증폭 키트의 제조 |
| WO2025141105A1 (en) | 2023-12-27 | 2025-07-03 | bioMérieux | Specific probes for the detection of nucleic acids, methods and uses |
| CN119177164A (zh) * | 2024-11-12 | 2024-12-24 | 东莞市松山湖中心医院 | 一种高速pcr扩增加热装置 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2065719A1 (en) * | 1991-04-30 | 1992-10-31 | John B. Findlay | Nucleic acid amplification and detection methods using rapid polymerase chain reaction cycle |
| US5436149A (en) | 1993-02-19 | 1995-07-25 | Barnes; Wayne M. | Thermostable DNA polymerase with enhanced thermostability and enhanced length and efficiency of primer extension |
| AU7551594A (en) * | 1993-07-29 | 1995-02-28 | MURASHIGE, Kate H. | Method for recognition of the nucleotide sequence of a purified dna segment |
| DE69638318D1 (de) | 1995-06-07 | 2011-02-17 | Gilead Sciences Inc | Nukleinsäureliganden, die an DNA-Polymerasen binden und diese inhibieren |
| AU7073096A (en) | 1995-09-19 | 1997-04-09 | University Of Massachusetts | Inhibited biological degradation of oligodeoxynucleotides |
| EP1033411B1 (en) * | 1996-06-04 | 2006-02-22 | University of Utah Research Foundation | Fluorescent donor-acceptor pair |
| US6210882B1 (en) | 1998-01-29 | 2001-04-03 | Mayo Foundation For Medical Education And Reseach | Rapid thermocycling for sample analysis |
| US6780588B2 (en) * | 2001-05-07 | 2004-08-24 | Applera Corporation | Methods for the reduction of stutter in microsatellite amplification |
| KR20030073875A (ko) | 2002-03-13 | 2003-09-19 | 주식회사 하이닉스반도체 | 반도체소자의 소자분리패턴 형성방법 |
| US20040241655A1 (en) * | 2003-05-29 | 2004-12-02 | Yuchi Hwang | Conditional touchdown multiplex polymerase chain reaction |
| US8232091B2 (en) * | 2006-05-17 | 2012-07-31 | California Institute Of Technology | Thermal cycling system |
| KR20080029233A (ko) | 2006-09-28 | 2008-04-03 | 삼성전자주식회사 | 핵산 증폭 및 혼성화를 단일 고체 지지체에서 수행하는방법 및 장치 |
| JP5191041B2 (ja) | 2007-04-05 | 2013-04-24 | エフ．ホフマン−ラ ロシュ アーゲー | 急速ワンステップｒｔ−ｐｃｒ |
| WO2009105499A1 (en) * | 2008-02-20 | 2009-08-27 | Termaat Joel R | Thermocycler and sample vessel for rapid amplification of dna |
| CA2658520C (en) | 2008-03-19 | 2016-11-08 | F. Hoffmann-La Roche Ag | Nucleic acid amplification in the presence of modified randomers |
| DK2279263T3 (da) | 2008-04-30 | 2013-11-11 | Integrated Dna Tech Inc | Rnase-h-baserede assays med anvendelse af modificerede rna-monomerer |
| US8349563B2 (en) * | 2008-11-18 | 2013-01-08 | Life Technologies Corporation | Sequence amplification with target primers |
| CN101407850B (zh) * | 2008-11-20 | 2011-01-05 | 江苏出入境检验检疫局动植物与食品检测中心 | 猴痘病毒的pcr快速检测试剂盒及检测方法 |
| WO2010104478A1 (en) * | 2009-03-10 | 2010-09-16 | Agency For Science, Technology And Research | Apparatus for processing a biological and/or chemical sample |
| DK2539472T3 (da) | 2010-02-26 | 2015-08-24 | Hennessy Lori | Hurtig pcr til str genotypebestemmelse |
| DK3109326T3 (da) | 2010-06-21 | 2022-02-14 | Life Technologies Corp | Sammensætning og fremgangsmåde til nukleinsyresyntese og amplifikation under anvendelse af rt |
| JP2012118055A (ja) * | 2010-11-12 | 2012-06-21 | Sony Corp | 反応処理装置及び反応処理方法 |
| US9168530B2 (en) * | 2010-12-17 | 2015-10-27 | Bjs Ip Ltd. | Methods and systems for fast PCR heating |
| US10273532B2 (en) * | 2012-03-09 | 2019-04-30 | National Institute Of Advanced Industrial Science And Technology | Nucleic acid amplification method |
| EP2855692B1 (en) | 2012-05-24 | 2019-07-24 | University of Utah Research Foundation | Extreme pcr |
| US9353409B2 (en) | 2013-01-15 | 2016-05-31 | Jun Euihum Lee | Compositions and methods for RT-PCR |
| WO2015069743A1 (en) * | 2013-11-05 | 2015-05-14 | Biofire Diagnostics, Llc | Induction pcr |
-
2013
- 2013-05-23 EP EP13793389.1A patent/EP2855692B1/en active Active
- 2013-05-23 PL PL21184359.4T patent/PL3957748T3/pl unknown
- 2013-05-23 CA CA2873991A patent/CA2873991C/en active Active
- 2013-05-23 PT PT137933891T patent/PT2855692T/pt unknown
- 2013-05-23 PL PL19166256T patent/PL3539666T3/pl unknown
- 2013-05-23 SG SG11201407427WA patent/SG11201407427WA/en unknown
- 2013-05-23 ES ES21184359T patent/ES3011358T3/es active Active
- 2013-05-23 EP EP21184359.4A patent/EP3957748B1/en active Active
- 2013-05-23 ES ES13793389T patent/ES2749700T3/es active Active
- 2013-05-23 US US14/403,369 patent/US9932634B2/en active Active
- 2013-05-23 DK DK13793389.1T patent/DK2855692T3/da active
- 2013-05-23 EP EP25227871.8A patent/EP4699698A2/en active Pending
- 2013-05-23 AU AU2013266246A patent/AU2013266246B2/en active Active
- 2013-05-23 SG SG10201800645WA patent/SG10201800645WA/en unknown
- 2013-05-23 PT PT191662568T patent/PT3539666T/pt unknown
- 2013-05-23 EP EP19166256.8A patent/EP3539666B1/en active Active
- 2013-05-23 DK DK19166256.8T patent/DK3539666T3/da active
- 2013-05-23 ES ES19166256T patent/ES2889348T3/es active Active
- 2013-05-23 CN CN201810059052.4A patent/CN108251271A/zh active Pending
- 2013-05-23 WO PCT/US2013/042473 patent/WO2013177429A2/en not_active Ceased
- 2013-05-23 SG SG10201810110RA patent/SG10201810110RA/en unknown
- 2013-05-23 EP EP24191572.7A patent/EP4442366A3/en active Pending
- 2013-05-23 JP JP2015514196A patent/JP6316802B2/ja active Active
- 2013-05-23 CN CN201380039367.8A patent/CN104662160B/zh active Active
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2018
- 2018-02-07 US US15/890,843 patent/US10144960B2/en active Active
- 2018-03-27 JP JP2018060111A patent/JP6731012B2/ja active Active
- 2018-11-02 US US16/179,383 patent/US11021744B2/en active Active
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2020
- 2020-04-07 JP JP2020069158A patent/JP7032818B2/ja active Active
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2021
- 2021-04-29 US US17/244,000 patent/US11834708B2/en active Active
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2023
- 2023-10-25 US US18/494,072 patent/US20240068021A1/en active Pending
-
2025
- 2025-12-17 US US19/423,536 patent/US20260110023A1/en active Pending
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| BR112014000755A2 (pt) | dispositivo de entrada | |
| DE112011104942A5 (de) | Eingabevorrichtung | |
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