DK354482A - Fremgangsmaade til fremstilling af substituerede pyridazinderivater - Google Patents

Fremgangsmaade til fremstilling af substituerede pyridazinderivater Download PDF

Info

Publication number: DK354482A
Authority: DK; Denmark
Prior art keywords: procedure; preparing substituted; pyridazine derivatives; substituted pyridazine; derivatives
Prior art date: 1981-08-07

Application number

DK354482A

Other languages

English (en)

Other versions

DK148795C (da

DK148795B (da

Inventor

J-P Kan

K Biziere

C G Wermuth

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-07

Filing date

1982-08-06

Publication date

1983-02-08

1982-08-06 Application filed by Sanofi Sa filed Critical Sanofi Sa

1983-02-08 Publication of DK354482A publication Critical patent/DK354482A/da

1985-09-30 Publication of DK148795B publication Critical patent/DK148795B/da

1986-03-10 Application granted granted Critical

1986-03-10 Publication of DK148795C publication Critical patent/DK148795C/da

Links

PBMFSQRYOILNGV-UHFFFAOYSA-N pyridazine Chemical class C1=CC=NN=C1 PBMFSQRYOILNGV-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK354482A 1981-08-07 1982-08-06 Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf DK148795C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8115380A FR2510998B1 (fr)	1981-08-07	1981-08-07	Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR8115380		1981-08-07

Publications (3)

Publication Number	Publication Date
DK354482A true DK354482A (da)	1983-02-08
DK148795B DK148795B (da)	1985-09-30
DK148795C DK148795C (da)	1986-03-10

Family

ID=9261294

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK354382A DK148537C (da)	1981-08-07	1982-08-06	Analogifremgangsmaade til fremstilling af 3-aminopyridazinforbindelser eller farmaceutisk acceptable salte deraf
DK354482A DK148795C (da)	1981-08-07	1982-08-06	Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK354382A DK148537C (da)	1981-08-07	1982-08-06	Analogifremgangsmaade til fremstilling af 3-aminopyridazinforbindelser eller farmaceutisk acceptable salte deraf

Country Status (30)

Country	Link
US (1)	US4508720A (da)
EP (2)	EP0072726B1 (da)
JP (2)	JPS5877868A (da)
KR (2)	KR890001569B1 (da)
AR (2)	AR231441A1 (da)
AT (2)	ATE18216T1 (da)
AU (2)	AU548930B2 (da)
CA (2)	CA1179346A (da)
CS (2)	CS229940B2 (da)
DD (2)	DD202715A5 (da)
DE (2)	DE3269383D1 (da)
DK (2)	DK148537C (da)
EG (2)	EG15747A (da)
ES (2)	ES514794A0 (da)
FI (2)	FI72969C (da)
FR (1)	FR2510998B1 (da)
GR (2)	GR76429B (da)
HU (2)	HU190028B (da)
IE (2)	IE53388B1 (da)
IL (2)	IL66409A (da)
MA (2)	MA19562A1 (da)
NO (2)	NO157861C (da)
NZ (2)	NZ201518A (da)
OA (2)	OA07175A (da)
PH (1)	PH18545A (da)
PL (2)	PL137199B1 (da)
PT (2)	PT75351B (da)
SU (2)	SU1140685A3 (da)
YU (2)	YU171882A (da)
ZA (2)	ZA825512B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2540113A1 (fr) *	1983-01-27	1984-08-03	Sanofi Sa	Acides derives de la pyridazine actifs sur le systeme nerveux central
CA1218655A (en) *	1983-01-28	1987-03-03	Kathleen Biziere	Process for the preparation of pyridazine derivatives having a psychotropic action
US4628088A (en) *	1984-07-17	1986-12-09	Eli Lilly And Company	Preparation of substituted pyridazines
DE3664772D1 (en) *	1985-01-14	1989-09-07	Boehringer Ingelheim Kg	12-amino pyridazinoû4',5':3,4¨pyrroloû2,1-a¨isoquinolines, process for their preparation and use
FR2665442B1 (fr) *	1990-07-31	1992-12-04	Sanofi Sa	Derives d'alkyl-6 pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642648B1 (fr) *	1989-02-07	1991-06-21	Sanofi Sa	Utilisation de derives d'alkyl-5 pyridazine comme medicaments actifs sur le systeme cholinergique
FR2654727B1 (fr) *	1989-11-17	1992-03-27	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
US5461053A (en) *	1989-02-07	1995-10-24	Sanofi	Pyridazine derivatives
US5631255A (en) *	1989-02-07	1997-05-20	Sanofi	Pyridazine derivatives
PT93060B (pt)	1989-02-07	1995-12-29	Sanofi Sa	Processo para a obtencao de derivados de piridazina e de composicoes farmaceuticas que os contem
FR2663326B2 (fr) *	1989-11-17	1992-10-16	Sanofi Sa	Derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant.
FR2642754B1 (fr) *	1989-02-07	1991-05-24	Sanofi Sa	Nouveaux derives de la pyridazine, procede de preparation et compositions pharmaceutiques en contenant
FR2676444B1 (fr) *	1991-05-16	1995-03-10	Sanofi Elf	Nouveaux derives d'amino-3 pyridazines actifs sur le systeme nerveux central, procede de preparation et compositions pharmaceutiques en contenant.
US20100210590A1 (en) *	1995-09-27	2010-08-19	Northwestern University	Compositions and treatments for seizure-related disorders
EP2264014A1 (en) *	2001-08-31	2010-12-22	Université Louis Pasteur	Substituted pyridazines as anti-inflammatory agents and protein kinase inhibitors
US20060235021A1 (en) *	2002-08-13	2006-10-19	Wesley Blackaby	Phenylpyridazine derivatives as ligands for gaba receptors
CA2589106C (en)	2004-11-02	2015-07-21	Northwestern University	Pyridazine compounds, compositions and methods and their use in treating inflammatory diseases
JP2008518955A (ja) *	2004-11-02	2008-06-05	ノースウェスタンユニバーシティ	ピリダジン化合物および方法
US8158627B2 (en) *	2006-04-28	2012-04-17	Northwestern University	Compositions and treatments using pyridazine compounds and cholinesterase inhibitors
US20100168120A1 (en) *	2006-04-28	2010-07-01	Neuromedix Inc.	Salts of pyridazine compounds
AU2007243280A1 (en) *	2006-04-28	2007-11-08	Northwestern University	Formulations containing pyridazine compounds for treating neuroinflammatory diseases
RU2555969C1 (ru) *	2014-07-09	2015-07-10	Юлия Алексеевна Щепочкина	Керамическая масса для изготовления облицовочной плитки

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1345880A (en) *	1971-06-18	1974-02-06	Cepbepe	Pyridazine derivatives

1981
- 1981-08-07 FR FR8115380A patent/FR2510998B1/fr not_active Expired
1982
- 1982-07-21 NO NO822509A patent/NO157861C/no unknown
- 1982-07-21 NO NO822510A patent/NO157102C/no unknown
- 1982-07-23 IE IE1779/82A patent/IE53388B1/en not_active IP Right Cessation
- 1982-07-23 IE IE1778/82A patent/IE53387B1/en not_active IP Right Cessation
- 1982-07-26 GR GR68868A patent/GR76429B/el unknown
- 1982-07-26 GR GR68873A patent/GR76430B/el unknown
- 1982-07-27 IL IL66409A patent/IL66409A/xx unknown
- 1982-07-27 IL IL66408A patent/IL66408A/xx unknown
- 1982-07-29 AU AU86553/82A patent/AU548930B2/en not_active Ceased
- 1982-07-29 US US06/402,906 patent/US4508720A/en not_active Expired - Fee Related
- 1982-07-29 AU AU86554/82A patent/AU548931B2/en not_active Ceased
- 1982-07-30 PT PT75351A patent/PT75351B/pt not_active IP Right Cessation
- 1982-07-30 EP EP82401425A patent/EP0072726B1/fr not_active Expired
- 1982-07-30 ZA ZA825512A patent/ZA825512B/xx unknown
- 1982-07-30 PT PT75350A patent/PT75350B/pt not_active IP Right Cessation
- 1982-07-30 DE DE8282401424T patent/DE3269383D1/de not_active Expired
- 1982-07-30 DE DE8282401425T patent/DE3262671D1/de not_active Expired
- 1982-07-30 AT AT82401424T patent/ATE18216T1/de not_active IP Right Cessation
- 1982-07-30 AT AT82401425T patent/ATE12227T1/de not_active IP Right Cessation
- 1982-07-30 ZA ZA825513A patent/ZA825513B/xx unknown
- 1982-07-30 EP EP82401424A patent/EP0074863B1/fr not_active Expired
- 1982-08-02 MA MA19773A patent/MA19562A1/fr unknown
- 1982-08-02 MA MA19771A patent/MA19560A1/fr unknown
- 1982-08-03 CS CS825799A patent/CS229940B2/cs unknown
- 1982-08-03 CS CS825800A patent/CS229941B2/cs unknown
- 1982-08-04 EG EG82474A patent/EG15747A/xx active
- 1982-08-04 EG EG473/82A patent/EG15788A/xx active
- 1982-08-06 JP JP57137833A patent/JPS5877868A/ja active Pending
- 1982-08-06 NZ NZ201518A patent/NZ201518A/en unknown
- 1982-08-06 SU SU823476698A patent/SU1140685A3/ru active
- 1982-08-06 FI FI822748A patent/FI72969C/fi not_active IP Right Cessation
- 1982-08-06 OA OA57767A patent/OA07175A/xx unknown
- 1982-08-06 PH PH27679A patent/PH18545A/en unknown
- 1982-08-06 JP JP57137832A patent/JPS5877867A/ja active Granted
- 1982-08-06 PL PL1982237808A patent/PL137199B1/pl unknown
- 1982-08-06 PL PL1982237809A patent/PL130647B1/pl unknown
- 1982-08-06 DK DK354382A patent/DK148537C/da not_active IP Right Cessation
- 1982-08-06 NZ NZ201520A patent/NZ201520A/xx unknown
- 1982-08-06 HU HU822545A patent/HU190028B/hu not_active IP Right Cessation
- 1982-08-06 FI FI822747A patent/FI72968C/fi not_active IP Right Cessation
- 1982-08-06 SU SU823475704A patent/SU1138024A3/ru active
- 1982-08-06 YU YU01718/82A patent/YU171882A/xx unknown
- 1982-08-06 YU YU01720/82A patent/YU172082A/xx unknown
- 1982-08-06 HU HU822542A patent/HU189166B/hu not_active IP Right Cessation
- 1982-08-06 CA CA000408844A patent/CA1179346A/en not_active Expired
- 1982-08-06 ES ES514794A patent/ES514794A0/es active Granted
- 1982-08-06 OA OA57768A patent/OA07176A/xx unknown
- 1982-08-06 CA CA000408843A patent/CA1174240A/en not_active Expired
- 1982-08-06 ES ES514795A patent/ES514795A0/es active Granted
- 1982-08-06 AR AR290242A patent/AR231441A1/es active
- 1982-08-06 DK DK354482A patent/DK148795C/da not_active IP Right Cessation
- 1982-08-06 AR AR290243A patent/AR231637A1/es active
- 1982-08-07 KR KR8203557A patent/KR890001569B1/ko not_active Expired
- 1982-08-07 KR KR8203558A patent/KR880001624B1/ko not_active Expired
- 1982-08-09 DD DD82242356A patent/DD202715A5/de unknown
- 1982-08-09 DD DD82242359A patent/DD202549A5/de unknown

Also Published As

Publication number	Publication date
FR2510998A1 (fr)	1983-02-11
JPH0459312B2 (da)	1992-09-21
OA07176A (fr)	1984-04-30
NO157102B (no)	1987-10-12
NO822509L (no)	1983-02-08
FI72968C (fi)	1987-08-10
AU548931B2 (en)	1986-01-09
AR231637A1 (es)	1985-01-31
PT75350A (fr)	1982-08-01
KR890001569B1 (ko)	1989-05-08
HU189166B (en)	1986-06-30
SU1140685A3 (ru)	1985-02-15
KR840001159A (ko)	1984-03-28
IE53387B1 (en)	1988-10-26
KR840001145A (ko)	1984-03-28
EP0072726A1 (fr)	1983-02-23
PL237809A1 (en)	1983-02-28
PT75350B (fr)	1984-08-01
PT75351A (fr)	1982-08-01
KR880001624B1 (ko)	1988-09-02
GR76429B (da)	1984-08-10
FI72969C (fi)	1987-08-10
EP0074863A1 (fr)	1983-03-23
DD202549A5 (de)	1983-09-21
ATE18216T1 (de)	1986-03-15
IL66409A0 (en)	1982-11-30
FI822748A0 (fi)	1982-08-06
CA1174240A (en)	1984-09-11
AR231441A1 (es)	1984-11-30
CS229940B2 (en)	1984-07-16
FI72968B (fi)	1987-04-30
IE821778L (en)	1983-02-07
AU8655482A (en)	1983-02-10
IL66409A (en)	1985-09-29
ES8305737A1 (es)	1983-04-16
ES8305738A1 (es)	1983-04-16
ZA825513B (en)	1983-06-29
PL137199B1 (en)	1986-05-31
ZA825512B (en)	1983-06-29
NZ201520A (en)	1985-04-30
HU190028B (en)	1986-08-28
NO157102C (no)	1988-01-20
YU171882A (en)	1985-03-20
DK354382A (da)	1983-02-08
AU8655382A (en)	1983-02-10
NO822510L (no)	1983-02-08
FI822747A0 (fi)	1982-08-06
PH18545A (en)	1985-08-09
DK148795C (da)	1986-03-10
DK148537C (da)	1986-01-13
NO157861B (no)	1988-02-22
ATE12227T1 (de)	1985-04-15
NO157861C (no)	1988-06-01
IE53388B1 (en)	1988-10-26
EG15747A (en)	1986-06-30
PL130647B1 (en)	1984-08-31
IE821779L (en)	1983-02-07
ES514795A0 (es)	1983-04-16
IL66408A0 (en)	1982-11-30
SU1138024A3 (ru)	1985-01-30
ES514794A0 (es)	1983-04-16
FI822748L (fi)	1983-02-08
EP0072726B1 (fr)	1985-03-20
CA1179346A (en)	1984-12-11
DK148537B (da)	1985-07-29
DE3262671D1 (en)	1985-04-25
EP0074863B1 (fr)	1986-02-26
FI822747L (fi)	1983-02-08
YU172082A (en)	1985-03-20
FR2510998B1 (fr)	1986-01-10
DK148795B (da)	1985-09-30
PT75351B (fr)	1984-08-01
DE3269383D1 (en)	1986-04-03
EG15788A (en)	1986-09-30
IL66408A (en)	1985-12-31
MA19562A1 (fr)	1983-04-01
AU548930B2 (en)	1986-01-09
GR76430B (da)	1984-08-10
JPS5877867A (ja)	1983-05-11
PL237808A1 (en)	1983-02-28
OA07175A (fr)	1984-04-30
JPS5877868A (ja)	1983-05-11
CS229941B2 (en)	1984-07-16
MA19560A1 (fr)	1983-04-01
DD202715A5 (de)	1983-09-28
FI72969B (fi)	1987-04-30
NZ201518A (en)	1985-04-30
US4508720A (en)	1985-04-02

Legal Events

Date	Code	Title	Description
1994-04-25	PBP	Patent lapsed

Publication	Publication Date	Title
DK249581A (da)	1981-12-14	Fremgangsmaade til fremstilling af pyridazinderivater
DK470583A (da)	1984-04-14	Fremgangsmaade til fremstilling af 1-phenyl-2-piperidinopropanolderivater
DK112582A (da)	1982-09-17	Fremgangsmaade til fremstilling af triazolonderivater
DK354482A (da)	1983-02-08	Fremgangsmaade til fremstilling af substituerede pyridazinderivater
DK358782A (da)	1983-02-12	Fremgangsmaade til fremstilling af pyridazinderivater
DK150070C (da)	1987-11-09	Analogifremgangsmaade til fremstilling af n-dihydrothiazolyl-3-quinolincarboxamidderivater
DK316480A (da)	1981-01-24	Fremgangsmaade til fremstilling af pyridazinderivater
DK349682A (da)	1983-03-01	Fremgangsmaade til fremstilling af imidazoquinazolinderivater
DK312082A (da)	1983-01-14	Fremgangsmaade til fremstilling af benzothiazolsulfonamidderivater
DK160555C (da)	1991-09-16	Fremgangsmaade til fremstilling af eburnamoninderivater
DK156722C (da)	1990-02-19	Analogifremgangsmaade til fremstilling af 2-piperazinopyrimidinderivater
DK153583A (da)	1983-10-09	Fremgangsmaade til fremstilling af substituerede penemderivater
DK116982A (da)	1982-09-18	Fremgangsmaade til fremstilling af alkylendioxybenzenderivater
DK489381A (da)	1982-05-07	Fremgangsmaade til fremstilling af aminopropoxyphenylderivater
DK553582A (da)	1983-06-15	Fremgangsmaade til fremstilling af naphthoxyalkylaminer
DK372081A (da)	1982-02-24	Fremgangsmaade til fremstilling af fluorerede pentendiaminderivater
DK501781A (da)	1982-05-14	Fremgangsmaade til fremstilling af 2-oxoazetidin-derivater
DK4982A (da)	1982-07-10	Fremgangsmaade til fremstilling af pyridinylsubstituerede benzimidazolderivater
DK252981A (da)	1981-12-28	Fremgangsmaade til fremstilling af pyrimidinderivater
DK71783D0 (da)	1983-02-18	Fremgangsmade til fremstilling af pyrimidonderivater
DK395880A (da)	1981-03-20	Fremgangsmaade til fremstilling af pyridazinderivater
DK231581A (da)	1981-12-03	Fremgangsmaade til fremstilling af phenoxyaminopropanolderivater
DK371981A (da)	1982-02-24	Fremgangsmaade til fremstilling af aminoacetonitrilderivater
DK375882A (da)	1983-02-27	Fremgangsmaade til fremstilling af benzisoxazolderivater
DK245682A (da)	1982-12-03	Fremgangsmaade til fremstilling af basisk substituerede phenylacetonitril-forbindelser