DK3609898T3 - Forbindelser, der er nyttige som ret-hæmmere - Google Patents

Forbindelser, der er nyttige som ret-hæmmere Download PDF

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Publication number
DK3609898T3
DK3609898T3 DK18719276.0T DK18719276T DK3609898T3 DK 3609898 T3 DK3609898 T3 DK 3609898T3 DK 18719276 T DK18719276 T DK 18719276T DK 3609898 T3 DK3609898 T3 DK 3609898T3
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DK
Denmark
Prior art keywords
compounds useful
ret inhibitors
ret
inhibitors
compounds
Prior art date
Application number
DK18719276.0T
Other languages
English (en)
Inventor
Allan Jordan
Rebecca Newton
George Hynd
Jonathan Mark Sutton
Bohdan Waszkowycz
Original Assignee
Cancer Research Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of DK3609898T3 publication Critical patent/DK3609898T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
DK18719276.0T 2017-04-13 2018-04-13 Forbindelser, der er nyttige som ret-hæmmere DK3609898T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1705971.8A GB201705971D0 (en) 2017-04-13 2017-04-13 Inhibitor compounds
PCT/GB2018/050986 WO2018189553A1 (en) 2017-04-13 2018-04-13 Compounds useful as ret inhibitors

Publications (1)

Publication Number Publication Date
DK3609898T3 true DK3609898T3 (da) 2022-09-05

Family

ID=58744532

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18719276.0T DK3609898T3 (da) 2017-04-13 2018-04-13 Forbindelser, der er nyttige som ret-hæmmere

Country Status (21)

Country Link
US (4) US11352361B2 (da)
EP (2) EP3609898B1 (da)
JP (3) JP7277376B2 (da)
CN (2) CN110506043B (da)
AU (3) AU2018252251B2 (da)
BR (1) BR112019021231A2 (da)
CA (1) CA3059134A1 (da)
CY (1) CY1125896T1 (da)
DK (1) DK3609898T3 (da)
ES (1) ES2925077T3 (da)
GB (1) GB201705971D0 (da)
HR (1) HRP20221040T1 (da)
HU (1) HUE059716T2 (da)
LT (1) LT3609898T (da)
PL (1) PL3609898T3 (da)
PT (1) PT3609898T (da)
RS (1) RS63514B1 (da)
RU (1) RU2760669C2 (da)
SI (1) SI3609898T1 (da)
SM (1) SMT202200345T1 (da)
WO (1) WO2018189553A1 (da)

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Also Published As

Publication number Publication date
CA3059134A1 (en) 2018-10-18
SMT202200345T1 (it) 2022-09-14
JP7536949B2 (ja) 2024-08-20
SI3609898T1 (sl) 2022-11-30
HUE059716T2 (hu) 2022-12-28
WO2018189553A1 (en) 2018-10-18
PT3609898T (pt) 2022-08-25
US20200157107A1 (en) 2020-05-21
AU2024213175A1 (en) 2024-09-12
CN110506043A (zh) 2019-11-26
EP3609898B1 (en) 2022-06-01
EP3609898A1 (en) 2020-02-19
US11352361B2 (en) 2022-06-07
US20240132504A1 (en) 2024-04-25
RU2019132155A (ru) 2021-05-13
JP2020516636A (ja) 2020-06-11
AU2022202325A1 (en) 2022-04-28
CN115785100A (zh) 2023-03-14
HRP20221040T1 (hr) 2022-11-11
JP7277376B2 (ja) 2023-05-18
RU2019132155A3 (da) 2021-05-13
CN110506043B (zh) 2022-11-01
AU2022202325B2 (en) 2024-05-23
RS63514B1 (sr) 2022-09-30
RU2760669C2 (ru) 2021-11-29
US20220348585A1 (en) 2022-11-03
BR112019021231A2 (pt) 2020-04-28
CN115785100B (zh) 2025-01-07
PL3609898T3 (pl) 2022-09-26
US11680068B2 (en) 2023-06-20
LT3609898T (lt) 2022-09-12
JP2024161432A (ja) 2024-11-19
CY1125896T1 (el) 2026-02-25
AU2018252251B2 (en) 2022-03-31
EP4105219A1 (en) 2022-12-21
ES2925077T3 (es) 2022-10-13
US20250243202A1 (en) 2025-07-31
JP2023103326A (ja) 2023-07-26
GB201705971D0 (en) 2017-05-31
AU2018252251A1 (en) 2019-10-17

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