DK424387A - Humant placenta angiogen faktor, der er i stand til at stimulere syntesen af papillaer endothelial celleprotease, dna syntese og vandring - Google Patents

Humant placenta angiogen faktor, der er i stand til at stimulere syntesen af papillaer endothelial celleprotease, dna syntese og vandring

Info

Publication number
DK424387A
DK424387A DK424387A DK424387A DK424387A DK 424387 A DK424387 A DK 424387A DK 424387 A DK424387 A DK 424387A DK 424387 A DK424387 A DK 424387A DK 424387 A DK424387 A DK 424387A
Authority
DK
Denmark
Prior art keywords
angiogenic factor
synthesis
humant
angiogen
papilla
Prior art date
Application number
DK424387A
Other languages
English (en)
Other versions
DK424387D0 (da
Inventor
David A Moscatelli
Daniel B Rifkin
Andreas Sommer
Original Assignee
Synergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27420052&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK424387(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Synergen Inc filed Critical Synergen Inc
Publication of DK424387D0 publication Critical patent/DK424387D0/da
Publication of DK424387A publication Critical patent/DK424387A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/515Angiogenesic factors; Angiogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • C12N15/625DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/035Fusion polypeptide containing a localisation/targetting motif containing a signal for targeting to the external surface of a cell, e.g. to the outer membrane of Gram negative bacteria, GPI- anchored eukaryote proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK424387A 1985-12-17 1987-08-14 Humant placenta angiogen faktor, der er i stand til at stimulere syntesen af papillaer endothelial celleprotease, dna syntese og vandring DK424387A (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80987385A 1985-12-17 1985-12-17
US88855486A 1986-07-16 1986-07-16
US89582986A 1986-08-12 1986-08-12
PCT/US1986/002669 WO1987003885A1 (en) 1985-12-17 1986-12-12 Human placenta angiogenic factor capable of stimulating capillary endothelial cell protease synthesis, dna synthesis and migration

Publications (2)

Publication Number Publication Date
DK424387D0 DK424387D0 (da) 1987-08-14
DK424387A true DK424387A (da) 1987-08-14

Family

ID=27420052

Family Applications (1)

Application Number Title Priority Date Filing Date
DK424387A DK424387A (da) 1985-12-17 1987-08-14 Humant placenta angiogen faktor, der er i stand til at stimulere syntesen af papillaer endothelial celleprotease, dna syntese og vandring

Country Status (15)

Country Link
EP (1) EP0226181B1 (da)
JP (1) JPH10262668A (da)
KR (1) KR960015442B1 (da)
AT (1) ATE107315T1 (da)
AU (2) AU6774887A (da)
DE (1) DE3689921T2 (da)
DK (1) DK424387A (da)
ES (1) ES2056787T3 (da)
FI (1) FI93843C (da)
IE (1) IE863281L (da)
IL (1) IL80944A (da)
NO (1) NO177859C (da)
NZ (1) NZ218631A (da)
PT (1) PT83939B (da)
WO (1) WO1987003885A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5852177A (en) * 1987-02-24 1998-12-22 Takeda Chemical Industries, Ltd. Basic fibroblast growth factor (bFGF) muteins
US4900673A (en) * 1988-03-28 1990-02-13 President And Fellows Of Harvard College Mutant human angiogenin (angiogenesis factor with superior angiogenin activity) genes therefor and methods of expression
CA2002261A1 (en) * 1988-11-07 1990-05-07 Andreas Sommer High molecular weight human angiogenic factors
CA2108277A1 (en) * 1992-02-14 1993-08-15 Mitsuru Watanuki Preparation for the therapy of respiratory tract diseases
GB9203533D0 (en) * 1992-02-19 1992-04-08 Erba Carlo Spa Use of the conjugate between a fibroblast growth factor and a saporin in treating ocular pathologies
US6749850B1 (en) * 1999-08-18 2004-06-15 The General Hospital Corporation Methods, compositions and kits for promoting recovery from damage to the central nervous system
KR101004086B1 (ko) 2002-06-18 2010-12-27 에자이 알앤드디 매니지먼트 가부시키가이샤 유전자 치료용 초대 배양 지방세포
US8182840B2 (en) * 2005-09-27 2012-05-22 Tissue Tech, Inc. Amniotic membrane preparations and purified compositions and therapy for scar reversal and inhibition
CN111100191A (zh) * 2018-10-26 2020-05-05 神威药业集团有限公司 源于人胎盘的活性蛋白质或多肽及其用途
EP4545971A3 (en) 2020-07-16 2025-08-06 Caregen Co., Ltd. Peptide with neutralizing activity against severe acute respiratory syndrome coronavirus 2

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209587A (en) * 1978-12-29 1980-06-24 Monsanto Company Production of tumor angiogenesis factor by cell culture
US4225670A (en) * 1978-12-29 1980-09-30 Monsanto Company Production of tumor angiogenesis factor by cell culture
DE3110560A1 (de) * 1981-03-18 1982-10-14 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen "angiotropine der leukozyten und des entzuendungsgewebes: eine neue klasse natuerlicher chemotropischer mitogene fuer das richtungswachstum von blutgefaessen und zur neovaskularisierung von geweben"
US4529590A (en) * 1982-12-27 1985-07-16 Leveen Robert F Production of angiogenetic factor
GB2146523B (en) * 1983-09-13 1987-01-07 Ward Page Faulk Preparation for stimulating growth of blood vessels prepared from amniochorionic tissue and macrophages
ATE105868T1 (de) * 1985-09-12 1994-06-15 Scios Nova Inc Rekombinanter fibroblast-wachstumsfaktor.
IL81650A0 (en) * 1986-02-24 1987-09-16 Robapharm Ag Purified human angiogenic factor,method for its preparation and pharmaceutical preparations

Also Published As

Publication number Publication date
JPH10262668A (ja) 1998-10-06
NO177859C (no) 1995-12-06
FI882891L (fi) 1988-06-16
KR960015442B1 (ko) 1996-11-14
EP0226181A3 (en) 1989-03-08
FI882891A0 (fi) 1988-06-16
AU650649B2 (en) 1994-06-30
EP0226181B1 (en) 1994-06-15
AU6774887A (en) 1987-07-15
NO873437L (no) 1987-08-14
IL80944A (en) 1994-10-07
IL80944A0 (en) 1987-03-31
PT83939B (pt) 1989-05-31
KR880700820A (ko) 1988-04-12
ES2056787T3 (es) 1994-10-16
AU7629991A (en) 1991-08-08
DE3689921D1 (de) 1994-07-21
DK424387D0 (da) 1987-08-14
EP0226181A2 (en) 1987-06-24
FI93843C (fi) 1995-06-12
ATE107315T1 (de) 1994-07-15
NZ218631A (en) 1991-07-26
PT83939A (en) 1987-01-01
FI93843B (fi) 1995-02-28
NO177859B (no) 1995-08-28
WO1987003885A1 (en) 1987-07-02
IE863281L (en) 1987-06-17
NO873437D0 (no) 1987-08-14
DE3689921T2 (de) 1994-09-22

Similar Documents

Publication Publication Date Title
DK58789D0 (da) Proteiner med faktor viii-aktivitet, fremgangsmaade til deres fremstilling ved anvendelse af genetisk konstruerede celler og farmaceutiske kompositioner indeholdende proteinerne
AR006188A1 (es) "composicion farmaceutica para inhibir la actividad de serinproteasa, metodo in vitro para inhibir la actividad de serinproteasa y metodo para preparar dicha composicion".
DK601786A (da) Hidtil ukendte prokoagulationsproteiner
NO177678C (no) Fremgangsmåte for fremstilling av et terapeutisk aktivt, rekombinant protein som har ASP-aktivitet, ekspresjonssystem samt DNA som koder for nevnte protein
DE68929043D1 (de) Für androgen-rezeptor-protein kodierende dna
ATE113961T1 (de) Therapeutische peptide.
DK424387A (da) Humant placenta angiogen faktor, der er i stand til at stimulere syntesen af papillaer endothelial celleprotease, dna syntese og vandring
NO960309L (no) Agonister og antagonister for humaninterleukin-10
DK421787D0 (da) Dna-konstruktion, der er i stand til at dirigere ekispression og sekretion af biologisk aktive pdgf-analoger i eukaryotiske celler, samt saadanne celler transformeret hermed og fremgangsmaade til fremstilling af pdgf-analogerne under anvendelse af disse
DE3777845D1 (de) Pharmazeutischer stoff fuer die behandlung von myelogener leukaemie.
ATE110742T1 (de) Peptid-verbindungen.
NO914720L (no) Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner
DK288789A (da) Peptider og syreadditionssalte deraf, deres fremstilling og anvendelse
ATE168698T1 (de) Zubereitungen zur verwendung bei der behandlung von psoriasis und von neuropsychiatrischen krankheiten
DE3881467D1 (de) Vasokonstriktor-peptid.
DK595187A (da) Minactivin og fremgangsmaade til fremstilling deraf
IT1226713B (it) Procedimento per la preparazione di interleuchina 1 beta umana ricombinante in forma omogenea.
DE3680140D1 (de) Behandlung von parasiterkrankungen.
PT85226A (en) Process for the preparation of novel trombolytic proteins
CO4480761A1 (es) Metodo para movilizar celulas tronco hematopoyeticas

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment