DK493689D0 - Topisk ophthalmisk laegemiddel - Google Patents

Topisk ophthalmisk laegemiddel

Info

Publication number: DK493689D0
Authority: DK; Denmark
Prior art keywords: weight; eye; suspension; ophthalmic medicament; mosm
Prior art date: 1988-02-08

Application number

DK493689A

Other languages

English (en)

Other versions

DK493689A (da

DK167344B1 (da

Inventor

Santosh Kumar Chandrasekaran

Roy Duane Archibald

Jeffrey Paul Davis

Yansheng Su

Original Assignee

Insite Vision Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-08

Filing date

1989-10-06

Publication date

1989-10-06

1989-10-06 Application filed by Insite Vision Inc filed Critical Insite Vision Inc

1989-10-06 Publication of DK493689D0 publication Critical patent/DK493689D0/da

1989-12-01 Publication of DK493689A publication Critical patent/DK493689A/da

1993-10-18 Application granted granted Critical

1993-10-18 Publication of DK167344B1 publication Critical patent/DK167344B1/da

Links

230000000699 topical effect Effects 0.000 title abstract 2
229940023490 ophthalmic product Drugs 0.000 title 1
239000000725 suspension Substances 0.000 abstract 4
239000003814 drug Substances 0.000 abstract 3
KUQWZSZYIQGTHT-UHFFFAOYSA-N hexa-1,5-diene-3,4-diol Chemical compound C=CC(O)C(O)C=C KUQWZSZYIQGTHT-UHFFFAOYSA-N 0.000 abstract 2
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
239000007900 aqueous suspension Substances 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
229920006037 cross link polymer Polymers 0.000 abstract 1
239000003431 cross linking reagent Substances 0.000 abstract 1
239000000839 emulsion Substances 0.000 abstract 1
239000012530 fluid Substances 0.000 abstract 1
FAOZLTXFLGPHNG-KNAQIMQKSA-N fluorometholone Chemical compound C([C@@]12C)=CC(=O)C=C1[C@@H](C)C[C@@H]1[C@]2(F)[C@@H](O)C[C@]2(C)[C@@](O)(C(C)=O)CC[C@H]21 FAOZLTXFLGPHNG-KNAQIMQKSA-N 0.000 abstract 1
229960001048 fluorometholone Drugs 0.000 abstract 1
239000000178 monomer Substances 0.000 abstract 1
230000003204 osmotic effect Effects 0.000 abstract 1
239000002245 particle Substances 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1
230000000379 polymerizing effect Effects 0.000 abstract 1
238000013268 sustained release Methods 0.000 abstract 1
239000012730 sustained-release form Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Ophthalmology & Optometry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
Liquid Crystal Substances (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK493689A 1988-02-08 1989-10-06 Topisk ophthalmisk laegemiddel samt fremgangsmaade til fremstilling af dette DK167344B1 (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US15376288A	1988-02-08	1988-02-08
US15376288		1988-02-08
US30111489A	1989-01-25	1989-01-25
US30111489		1989-01-25
US8900451		1989-02-08
PCT/US1989/000451 WO1989006964A1 (en)	1988-02-08	1989-02-08	Ophthalmic suspensions

Publications (3)

Publication Number	Publication Date
DK493689D0 true DK493689D0 (da)	1989-10-06
DK493689A DK493689A (da)	1989-12-01
DK167344B1 DK167344B1 (da)	1993-10-18

Family

ID=26850837

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK493689A DK167344B1 (da)	1988-02-08	1989-10-06	Topisk ophthalmisk laegemiddel samt fremgangsmaade til fremstilling af dette
DK047793A DK168727B1 (da)	1988-02-08	1993-04-27	Ophthalmisk præparat samt fremgangsmåde til fremstilling heraf

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK047793A DK168727B1 (da)	1988-02-08	1993-04-27	Ophthalmisk præparat samt fremgangsmåde til fremstilling heraf

Country Status (10)

Country	Link
EP (1)	EP0362321B1 (da)
JP (1)	JP2814637B2 (da)
AT (1)	ATE91408T1 (da)
CA (1)	CA1336500C (da)
DE (1)	DE68907545T2 (da)
DK (2)	DK167344B1 (da)
ES (1)	ES2012634A6 (da)
IE (1)	IE63392B1 (da)
NO (1)	NO176696C (da)
WO (1)	WO1989006964A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5192535A (en) *	1988-02-08	1993-03-09	Insite Vision Incorporated	Ophthalmic suspensions
US5188826A (en) *	1988-02-08	1993-02-23	Insite Vision Incorporated	Topical ophthalmic suspensions
US5521222A (en) *	1989-09-28	1996-05-28	Alcon Laboratories, Inc.	Topical ophthalmic pharmaceutical vehicles
US5461081A (en) *	1989-09-28	1995-10-24	Alcon Laboratories, Inc.	Topical ophthalmic pharmaceutical vehicles
FR2653018A1 (fr)	1989-10-17	1991-04-19	Merck Sharp & Dohme	Composition ophtalmique non solide a base de microparticules de polymere contenant au moins un principe actif en suspension dans un milieu dispersant et procede de preparation de ladite composition.
US6017521A (en) *	1989-10-31	2000-01-25	Columbia Laboratories, Inc.	Use of polycarboxylic acid polymers to treat vaginal infections
HU227563B1 (en) *	1989-10-31	2011-08-29	Columbia Lab Bermuda Ltd	Process for production of composition for moisturizing of tissue
ATE113841T1 (de) *	1989-10-31	1994-11-15	Columbia Lab Inc	Mittel zur feuchthaltung vaginalen gewebes.
DE69012955T2 (de) *	1989-10-31	1995-02-09	Columbia Laboratories, Inc., Miami, Fla.	Verfahren zur Feuchthaltung von Gewebe und Mittel dazu.
US5124154A (en) *	1990-06-12	1992-06-23	Insite Vision Incorporated	Aminosteroids for ophthalmic use
AU8444291A (en) *	1990-08-21	1992-03-17	Oramed, Inc.	Controlled release formulations and method
US5686094A (en) *	1991-04-01	1997-11-11	Theratech, Inc.	Controlled release formulations for the treatment of xerostomia
CA2055522A1 (en) *	1990-12-12	1992-06-13	Masako Andoh	Microspheres for ophthalmic use
JP2873530B2 (ja) *	1991-12-13	1999-03-24	参天製薬株式会社	ニュートン型粘性を示すカルボキシビニルポリマー含有点眼液基剤
US5292517A (en) *	1992-02-25	1994-03-08	Allergan, Inc.	pH sensitive, reversible gelling, copolymeric erodible drug delivery system
AU5599594A (en) *	1992-11-16	1994-06-08	Ciba-Geigy Ag	Polyvinyl alcohol/borate ophthalmic drug delivery system
JPH08503951A (ja) *	1992-12-02	1996-04-30	インサイト・ビジョン・インコーポレイテッド	シクロデキストリンとポリマーを用いた薬剤供給系
US5340572A (en) *	1993-02-08	1994-08-23	Insite Vision Incorporated	Alkaline ophthalmic suspensions
WO1995005803A1 (en) *	1993-08-20	1995-03-02	Alcon Laboratories, Inc.	Topical ophthalmic pharmaceutical vehicles
US5474985A (en) *	1993-12-22	1995-12-12	The Regents Of The University Of California	Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
JPH09510961A (ja) *	1994-01-14	1997-11-04	ジュニアシャヒニアン，リー	持続性および長期間の角膜鎮痛の方法
US5422116A (en) *	1994-02-18	1995-06-06	Ciba-Geigy Corporation	Liquid ophthalmic sustained release delivery system
IL114193A (en) *	1994-06-20	2000-02-29	Teva Pharma	Ophthalmic pharmaceutical compositions based on sodium alginate
US5789169A (en) *	1994-11-03	1998-08-04	Regents Of The University Of California	Methods for the diagnosis of glaucoma
US5606043A (en)	1994-11-03	1997-02-25	The Regents Of The University Of California	Methods for the diagnosis of glaucoma
US5849879A (en) *	1994-11-03	1998-12-15	The Regents Of The University Of California	Methods for the diagnosis of glaucoma
US5603929A (en) *	1994-11-16	1997-02-18	Alcon Laboratories, Inc.	Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
AUPN327695A0 (en) *	1995-05-30	1995-06-22	Chemeq Pty. Limited	Chemotherapeutic compositions
US5674888A (en) *	1995-06-07	1997-10-07	University Of California	Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) *	1995-06-07	1997-02-04	Regents Of The University Of California	Methods for the cyto-protection of the trabecular meshwork
ZA966579B (en) *	1995-08-04	1998-02-02	Wakamoto Pharma Co Ltd	O/W emulsion composition for eye drops.
US6596777B1 (en)	1997-05-29	2003-07-22	Mcneil-Ppc, Inc.	Moisture containing compositions that are spreadable onto and adherable to biomembranes
US7138511B1 (en)	1997-01-28	2006-11-21	The Regents Of The University Of California	Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6475724B1 (en)	1997-01-28	2002-11-05	The Regents Of The University Of California	Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6171788B1 (en)	1997-01-28	2001-01-09	The Regents Of The University Of California	Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
DE19729879C2 (de) *	1997-07-11	1999-07-08	Mann Gerhard Chem Pharm Fab	Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin
US6258350B1 (en)	1999-01-20	2001-07-10	Alcon Manufacturing, Ltd.	Sustained release ophthalmic formulation
US6699492B2 (en) *	1999-03-31	2004-03-02	Insite Vision Incorporated	Quinolone carboxylic acid compositions and related methods of treatment
CA2456833A1 (en)	2001-08-10	2003-02-20	Masahiro Inohara	Polysaccharide-containing compositions and use thereof
US7001615B1 (en)	2001-12-07	2006-02-21	Alcon, Inc.	Sustained release ophthalmic, otic and nasal suspension
JP4777477B2 (ja) *	2009-09-30	2011-09-21	ロート製薬株式会社	点眼剤
TW201309343A (zh) *	2011-02-10	2013-03-01	參天製藥股份有限公司	經改善親水性藥物之藥物移行性之水性組成物
EP2758031A1 (en)	2011-09-22	2014-07-30	Bausch & Lomb Incorporated	Ophthalmic gel compositions
MX2015002208A (es)	2012-08-31	2015-05-08	Bausch & Lomb	Composiciones oftalmicas con acidos grasos omega-3.
EP3470059B1 (en)	2015-01-26	2020-04-01	Bausch & Lomb Incorporated	Ophthalmic suspension composition
CN113366025A (zh)	2019-01-30	2021-09-07	鲍希与洛姆伯股份有限公司	交联的聚合物网络及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3947573A (en) *	1969-12-01	1976-03-30	Burton, Parsons And Company, Inc.	Opthalmic solution
JPS6056684B2 (ja) *	1977-11-07	1985-12-11	東興薬品工業株式会社	点眼剤
US4271143A (en) *	1978-01-25	1981-06-02	Alcon Laboratories, Inc.	Sustained release ophthalmic drug dosage
US4478818A (en) *	1982-12-27	1984-10-23	Alza Corporation	Ocular preparation housing steroid in two different therapeutic forms
US4474751A (en) *	1983-05-16	1984-10-02	Merck & Co., Inc.	Ophthalmic drug delivery system utilizing thermosetting gels
ATE151286T1 (de) *	1983-11-14	1997-04-15	Columbia Lab Inc	Bioadhäsive mittel

1989
- 1989-02-01 IE IE32389A patent/IE63392B1/en not_active IP Right Cessation
- 1989-02-07 CA CA000590266A patent/CA1336500C/en not_active Expired - Lifetime
- 1989-02-07 ES ES8900427A patent/ES2012634A6/es not_active Expired - Fee Related
- 1989-02-08 AT AT89902873T patent/ATE91408T1/de not_active IP Right Cessation
- 1989-02-08 EP EP89902873A patent/EP0362321B1/en not_active Expired - Lifetime
- 1989-02-08 WO PCT/US1989/000451 patent/WO1989006964A1/en not_active Ceased
- 1989-02-08 DE DE89902873T patent/DE68907545T2/de not_active Expired - Lifetime
- 1989-02-08 JP JP1502665A patent/JP2814637B2/ja not_active Expired - Lifetime
- 1989-10-06 DK DK493689A patent/DK167344B1/da not_active IP Right Cessation
- 1989-10-06 NO NO894001A patent/NO176696C/no not_active IP Right Cessation
1993
- 1993-04-27 DK DK047793A patent/DK168727B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK493689A (da)	1989-12-01
EP0362321B1 (en)	1993-07-14
EP0362321A4 (en)	1991-05-08
DK168727B1 (da)	1994-05-30
NO176696B (no)	1995-02-06
ES2012634A6 (es)	1990-04-01
ATE91408T1 (de)	1993-07-15
NO894001D0 (no)	1989-10-06
NO176696C (no)	1995-05-16
CA1336500C (en)	1995-08-01
DK167344B1 (da)	1993-10-18
DE68907545D1 (de)	1993-08-19
NO894001L (no)	1989-12-08
DE68907545T2 (de)	1993-10-28
IE63392B1 (en)	1995-04-19
WO1989006964A1 (en)	1989-08-10
JPH02503201A (ja)	1990-10-04
IE890323L (en)	1989-08-08
EP0362321A1 (en)	1990-04-11
JP2814637B2 (ja)	1998-10-27
DK47793A (da)	1993-04-27
DK47793D0 (da)	1993-04-27

Legal Events

Date	Code	Title	Description
1993-10-18	B1	Patent granted (law 1993)
2009-02-23	PUP	Patent expired

Publication	Publication Date	Title
DE68907545D1 (de)	1993-08-19	Ophthalmische suspensionen.
ES2103815T3 (es)	1997-10-01	Suspensiones oftalmicas.
ATE192332T1 (de)	2000-05-15	Alkalische ophthalmische suspensionen
CA2086120A1 (en)	1992-01-07	Topical ophthalmic suspensions
DE3484165D1 (de)	1991-04-04	Vernetzte poroese polymere fuer eine kontrollierte wirkstoffabgabe.
CA2181715A1 (en)	1995-08-24	Liquid ophthalmic sustained release delivery system
KR920011478A (ko)	1992-07-24	안과용 미소구