DK680887A - Quinolinforbindelse og farmaceutiske praeparater med indhold af en saadan forbindelse - Google Patents

Quinolinforbindelse og farmaceutiske praeparater med indhold af en saadan forbindelse

Info

Publication number
DK680887A
DK680887A DK680887A DK680887A DK680887A DK 680887 A DK680887 A DK 680887A DK 680887 A DK680887 A DK 680887A DK 680887 A DK680887 A DK 680887A DK 680887 A DK680887 A DK 680887A
Authority
DK
Denmark
Prior art keywords
connection
quinol
pharmaceutical preparations
preparations containing
pharmaceutical
Prior art date
Application number
DK680887A
Other languages
English (en)
Other versions
DK163429B (da
DK163429C (da
DK680887D0 (da
Inventor
Arthur Page Phillips
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK680887D0 publication Critical patent/DK680887D0/da
Publication of DK680887A publication Critical patent/DK680887A/da
Publication of DK163429B publication Critical patent/DK163429B/da
Application granted granted Critical
Publication of DK163429C publication Critical patent/DK163429C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Secondary Cells (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK680887A 1986-12-23 1987-12-22 Carbostyrilderivat og farmaceutisk acceptable salte deraf, saadanne forbindelser til anvendelse som positive inotropiske midler, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater, farmaceutiske praeparater indeholdende en saadan forbindelse, samt fremgangsmaade til forbindelsernes fremstilling DK163429C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8630702 1986-12-23
GB868630702A GB8630702D0 (en) 1986-12-23 1986-12-23 Quinoline compound

Publications (4)

Publication Number Publication Date
DK680887D0 DK680887D0 (da) 1987-12-22
DK680887A true DK680887A (da) 1988-06-24
DK163429B DK163429B (da) 1992-03-02
DK163429C DK163429C (da) 1992-07-20

Family

ID=10609475

Family Applications (1)

Application Number Title Priority Date Filing Date
DK680887A DK163429C (da) 1986-12-23 1987-12-22 Carbostyrilderivat og farmaceutisk acceptable salte deraf, saadanne forbindelser til anvendelse som positive inotropiske midler, anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater, farmaceutiske praeparater indeholdende en saadan forbindelse, samt fremgangsmaade til forbindelsernes fremstilling

Country Status (22)

Country Link
US (1) US4937248A (da)
EP (1) EP0272910B1 (da)
JP (1) JPS63166866A (da)
KR (1) KR880007514A (da)
AT (1) ATE65993T1 (da)
AU (1) AU594220B2 (da)
CA (1) CA1318671C (da)
DE (1) DE3772015D1 (da)
DK (1) DK163429C (da)
ES (1) ES2029842T3 (da)
FI (1) FI90768C (da)
GB (1) GB8630702D0 (da)
GR (1) GR3002445T3 (da)
HU (1) HU196991B (da)
IE (1) IE60619B1 (da)
IL (1) IL84917A (da)
MX (1) MX9203788A (da)
MY (1) MY102277A (da)
NZ (1) NZ223036A (da)
PH (1) PH23448A (da)
PT (1) PT86448B (da)
ZA (1) ZA879615B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8820174D0 (en) * 1988-08-25 1988-09-28 Wellcome Found Quinoline compound
EP1017691A1 (en) * 1997-09-24 2000-07-12 Orion Corporation (Orion-Yhtyma Oy) Bisethers of 1-oxa, aza and thianaphthalen-2-ones as phospholamban inhibitors
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
KR20020038741A (ko) 1999-08-27 2002-05-23 윌리암 엘. 레스페스 안드로겐 수용체 조절 화합물 및 방법
JP2003508397A (ja) 1999-08-27 2003-03-04 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲンレセプターモジュレーターとしての8−置換−6−トリフルオロメチル−9−ピリド[3,2−g]キノリン化合物
AU7586600A (en) 1999-09-14 2001-04-17 Ligand Pharmaceuticals Incorporated Rxr modulators with improved pharmacologic profile
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
MXPA06001751A (es) 2003-08-22 2006-05-12 Ligand Pharm Inc Derivados de 6-cicloamino-2-quinolinona como compuestos moduladores de receptor de androgeno.
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
DK2681236T3 (da) 2011-03-01 2018-04-16 Synergy Pharmaceuticals Inc Fremgangsmåde til fremstilling af guanylat-cyclase-c-agonister
WO2014131024A2 (en) 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
AU2014305843B2 (en) 2013-08-09 2019-08-29 Ardelyx, Inc. Compounds and methods for inhibiting phosphate transport
EP4706758A3 (en) 2019-05-21 2026-05-06 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2616855A (en) * 1948-01-15 1952-11-04 Procter & Gamble Detergent composition
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
US4710507A (en) * 1983-12-22 1987-12-01 Pfizer Inc. Quinolone inotropic agents
CA1292234C (en) * 1984-05-29 1991-11-19 Simon Fraser Campbell Heterocyclic-substituted quinolone inotropic agents
US4760064A (en) * 1984-12-18 1988-07-26 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds, compositions containing same and processes for preparing same
US4845100A (en) * 1985-04-12 1989-07-04 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same
FR2580646A1 (fr) * 1985-04-19 1986-10-24 Synthelabo Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
ES2053480T3 (es) * 1986-07-31 1994-08-01 Otsuka Pharma Co Ltd Un procedimiento para preparar un derivado de carboestirilo.

Also Published As

Publication number Publication date
KR880007514A (ko) 1988-08-27
DK163429B (da) 1992-03-02
DK163429C (da) 1992-07-20
AU594220B2 (en) 1990-03-01
MY102277A (en) 1992-05-15
GB8630702D0 (en) 1987-02-04
US4937248A (en) 1990-06-26
FI875666A0 (fi) 1987-12-22
ES2029842T3 (es) 1992-10-01
FI90768C (fi) 1994-03-25
DK680887D0 (da) 1987-12-22
PT86448A (en) 1988-01-01
EP0272910B1 (en) 1991-08-07
IE873490L (en) 1988-06-23
GR3002445T3 (en) 1992-12-30
ATE65993T1 (de) 1991-08-15
NZ223036A (en) 1990-11-27
MX9203788A (es) 1992-07-01
FI875666L (fi) 1988-06-24
IL84917A0 (en) 1988-06-30
HU196991B (en) 1989-02-28
AU8293387A (en) 1988-06-23
EP0272910A1 (en) 1988-06-29
HUT45984A (en) 1988-09-28
JPS63166866A (ja) 1988-07-11
FI90768B (fi) 1993-12-15
DE3772015D1 (de) 1991-09-12
IE60619B1 (en) 1994-07-27
PH23448A (en) 1989-08-07
IL84917A (en) 1991-08-16
PT86448B (pt) 1990-11-20
ZA879615B (en) 1989-08-30
CA1318671C (en) 1993-06-01

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