ES2029842T3 - Procedimiento para preparar un derivado de quinolina. - Google Patents

Procedimiento para preparar un derivado de quinolina.

Info

Publication number
ES2029842T3
ES2029842T3 ES198787311275T ES87311275T ES2029842T3 ES 2029842 T3 ES2029842 T3 ES 2029842T3 ES 198787311275 T ES198787311275 T ES 198787311275T ES 87311275 T ES87311275 T ES 87311275T ES 2029842 T3 ES2029842 T3 ES 2029842T3
Authority
ES
Spain
Prior art keywords
prepare
procedure
quinoline derivative
quinoline
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198787311275T
Other languages
English (en)
Inventor
Arthur Page Phillips
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of ES2029842T3 publication Critical patent/ES2029842T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Superconductors And Manufacturing Methods Therefor (AREA)
  • Secondary Cells (AREA)
  • Carbon And Carbon Compounds (AREA)

Abstract

LA PRESENTE INVENCION TRATA DEL COMPUESTO DE FORMULA (I) Y SUS SALES.
ES198787311275T 1986-12-23 1987-12-22 Procedimiento para preparar un derivado de quinolina. Expired - Lifetime ES2029842T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868630702A GB8630702D0 (en) 1986-12-23 1986-12-23 Quinoline compound

Publications (1)

Publication Number Publication Date
ES2029842T3 true ES2029842T3 (es) 1992-10-01

Family

ID=10609475

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198787311275T Expired - Lifetime ES2029842T3 (es) 1986-12-23 1987-12-22 Procedimiento para preparar un derivado de quinolina.

Country Status (22)

Country Link
US (1) US4937248A (es)
EP (1) EP0272910B1 (es)
JP (1) JPS63166866A (es)
KR (1) KR880007514A (es)
AT (1) ATE65993T1 (es)
AU (1) AU594220B2 (es)
CA (1) CA1318671C (es)
DE (1) DE3772015D1 (es)
DK (1) DK163429C (es)
ES (1) ES2029842T3 (es)
FI (1) FI90768C (es)
GB (1) GB8630702D0 (es)
GR (1) GR3002445T3 (es)
HU (1) HU196991B (es)
IE (1) IE60619B1 (es)
IL (1) IL84917A (es)
MX (1) MX9203788A (es)
MY (1) MY102277A (es)
NZ (1) NZ223036A (es)
PH (1) PH23448A (es)
PT (1) PT86448B (es)
ZA (1) ZA879615B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166160A (en) * 1986-12-23 1992-11-24 Burroughs Wellcome Co. Quinoline compound
GB8820174D0 (en) * 1988-08-25 1988-09-28 Wellcome Found Quinoline compound
TR200000764T2 (tr) * 1997-09-24 2001-03-21 Orion Corporation Fosfolamban inhibitörleri olarak, 1-okza, aza ve tiyanaftalin-2-on'ların biseterleri.
US6667313B1 (en) 1999-08-27 2003-12-23 Ligand Pharmaceuticals Inc. 8-substituted-6-triflouromethyl-9-pyrido [3,2-G] quinoline compounds as androgen receptor modulators
US6566372B1 (en) 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
PL353792A1 (en) 1999-08-27 2003-12-01 Ligand Pharmaceuticals Incorporatedligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
WO2001019770A2 (en) 1999-09-14 2001-03-22 Ligand Pharmaceuticals Incorporated Rxr modulators with improved pharmacologic profile
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP4709759B2 (ja) 2003-08-22 2011-06-22 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲン受容体モジュレーター化合物としての６−シクロアミノ−２−キノリノン誘導体
MX2009013293A (es) 2007-06-04 2010-02-15 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA3100941C (en) 2011-03-01 2024-03-05 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
EP3718557A3 (en) 2013-02-25 2020-10-21 Bausch Health Ireland Limited Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
EA201592263A1 (ru) 2013-06-05 2016-05-31 Синерджи Фармасьютикалз, Инк. Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования
KR20160042039A (ko) 2013-08-09 2016-04-18 알데릭스, 인코포레이티드 인산염 수송을 억제하기 위한 화합물 및 방법
WO2020237096A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Combination for lowering serum phosphate in a patient

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2616855A (en) * 1948-01-15 1952-11-04 Procter & Gamble Detergent composition
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
JPS5777676A (en) * 1980-10-31 1982-05-15 Otsuka Pharmaceut Co Ltd Carbostyril derivative
PT79699B (en) * 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
NZ212209A (en) * 1984-05-29 1988-08-30 Pfizer Quinolone derivatives and pharmaceutical compositions
US4760064A (en) * 1984-12-18 1988-07-26 Otsuka Pharmaceutical Co., Ltd. Carbostyril compounds, compositions containing same and processes for preparing same
US4845100A (en) * 1985-04-12 1989-07-04 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same
FR2580646A1 (fr) * 1985-04-19 1986-10-24 Synthelabo Derives de 2(1h)-quinolinone, leur preparation et leur application en therapeutique
GB8529362D0 (en) * 1985-11-28 1986-01-02 Pfizer Ltd Quinolone cardiac stimulants
DK111387A (da) * 1986-03-05 1987-09-06 Otsuka Pharma Co Ltd Carbostyrilderivater og salte deraf, laegemiddel indeholdende saadanne derivater samt fremgangsmaade til fremstilling af derivaterne
US4886809A (en) * 1986-07-31 1989-12-12 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives and salts thereof

Also Published As

Publication number Publication date
IL84917A (en) 1991-08-16
FI875666A0 (fi) 1987-12-22
IE873490L (en) 1988-06-23
MX9203788A (es) 1992-07-01
JPS63166866A (ja) 1988-07-11
PT86448B (pt) 1990-11-20
MY102277A (en) 1992-05-15
DK680887A (da) 1988-06-24
FI875666L (fi) 1988-06-24
GB8630702D0 (en) 1987-02-04
AU8293387A (en) 1988-06-23
DK163429C (da) 1992-07-20
ATE65993T1 (de) 1991-08-15
HUT45984A (en) 1988-09-28
FI90768C (fi) 1994-03-25
AU594220B2 (en) 1990-03-01
CA1318671C (en) 1993-06-01
DK680887D0 (da) 1987-12-22
IE60619B1 (en) 1994-07-27
PH23448A (en) 1989-08-07
DK163429B (da) 1992-03-02
GR3002445T3 (en) 1992-12-30
HU196991B (en) 1989-02-28
ZA879615B (en) 1989-08-30
IL84917A0 (en) 1988-06-30
DE3772015D1 (de) 1991-09-12
KR880007514A (ko) 1988-08-27
EP0272910A1 (en) 1988-06-29
FI90768B (fi) 1993-12-15
EP0272910B1 (en) 1991-08-07
PT86448A (en) 1988-01-01
US4937248A (en) 1990-06-26
NZ223036A (en) 1990-11-27

Similar Documents

Publication Publication Date Title
MX9203338A (es) Nuevos derivados del oxico a_nor-esteroide-3-carboxilico.
ES2029786T3 (es) Procedimiento para preparar nuevos derivados de quinolina.
ES8800172A1 (es) Procedimiento para la preparacion de 3-ariluracilos
FR2375218A1 (fr) 2-imidazoline-5-ones a substitution chirale
ES8801222A1 (es) Un procedimiento para la preparacion de nuevos derivados de ciclopenta(d)pirimidina
DE3772015D1 (de) Chinolinverbindung.
FR2362170A1 (fr) Nouvelles polyurees
FR2387989A1 (fr) Analogues des alcaloides de l'ergot
ES2032752T3 (es) Procedimiento de preparacion de derivados de la 1-bencenosulfonil-2-oxo-5-alcoxi-pirrolidina.
ES8706692A1 (es) Un metodo para preparar nuevos derivados de cefem
FR2383185A1 (es)
FR2392959A1 (fr) Amino-acides et procede d'obtention
FR2361351A1 (fr) Intermediaires de preparation d'homologues de somatostatine
FR2394514A1 (fr) Nouvel acide cyclohexanecarboxylique et ses derives
ES2038684T3 (es) Procedimiento de preparacion de derivados de octahidroindol y de compuestos intermedios de su preparacion.
ES465503A1 (es) Procedimiento para preparar n-benzoilantranilato.
FR2359832A1 (fr) 1,3,5-tris-(2-chloroformyl-oxyethyl)-isocyanurate
FR2367761A1 (fr) Derives piperidylideniques de benzo-xanthenes,
ES2055708T3 (es) Peptidos.
DE3677465D1 (de) N-glykolylneuraminsaeurederivat.
FR2362129A1 (fr) 9-hydroxyhexahydrobenzo(c)quinoleines et intermediaires de synthese
FR2398752A1 (fr) Esters tetracarboxyliques de 2,2,6,6-tetramethyl-piperidino-spiro-dioxanol
ES468127A1 (es) Un procedimiento para la preparacion de nuevos derivados de pirido (2,1-b) quinazolina
ES8507506A1 (es) Procedimiento para la obtencion de derivados de diaril-imidazol.
ES8706122A1 (es) Un procedimiento para la preparacion de agentes inotropicos de quinolona

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 272910

Country of ref document: ES