DZ2978A1 - Composés chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant. - Google Patents

Composés chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant.

Info

Publication number: DZ2978A1
Authority: DZ; Algeria
Prior art keywords: pharmaceutical compositions; compositions containing; chemical compounds; new chemical; compounds modulating
Prior art date: 1998-12-23

Application number

DZ990278A

Other languages

English (en)

Inventor

Duncan Robert Armour

Blanda Luzia Christa Stammen

Manoussos Perros

David Anthony Price

Anthony Wood

Martin Paul Edwards

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-12-23

Filing date

1999-12-22

Publication date

2004-07-04

1998-12-23 Priority claimed from GBGB9828420.1A external-priority patent/GB9828420D0/en

1999-09-18 Priority claimed from GBGB9922009.7A external-priority patent/GB9922009D0/en

1999-12-22 Application filed by Pfizer filed Critical Pfizer

2004-07-04 Application granted granted Critical

2004-07-04 Publication of DZ2978A1 publication Critical patent/DZ2978A1/fr

Links

150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
AIDS & HIV (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Tropical Medicine & Parasitology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Compression, Expansion, Code Conversion, And Decoders (AREA)
Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

DZ990278A 1998-12-23 1999-12-22 Composés chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant. DZ2978A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9828420.1A GB9828420D0 (en)	1998-12-23	1998-12-23	CCR5 antagonists useful as anti-hiv agents
GBGB9922009.7A GB9922009D0 (en)	1999-09-18	1999-09-18	CCR5 Modulators

Publications (1)

Publication Number	Publication Date
DZ2978A1 true DZ2978A1 (fr)	2004-07-04

Family

ID=26314900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ990278A DZ2978A1 (fr)	1998-12-23	1999-12-22	Composés chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant.

Country Status (37)

Country	Link
US (1)	US7217714B1 (fr)
EP (1)	EP1140920A1 (fr)
JP (2)	JP3522691B2 (fr)
KR (1)	KR20010099931A (fr)
CN (1)	CN1150192C (fr)
AP (1)	AP2001002187A0 (fr)
AR (2)	AR023345A1 (fr)
AU (1)	AU769449B2 (fr)
BG (1)	BG105709A (fr)
BR (1)	BR9916585A (fr)
CA (1)	CA2350573C (fr)
CR (1)	CR6393A (fr)
CZ (1)	CZ20012297A3 (fr)
DZ (1)	DZ2978A1 (fr)
EA (1)	EA200100588A1 (fr)
EE (1)	EE200100344A (fr)
GE (1)	GEP20043161B (fr)
HK (1)	HK1039942B (fr)
HN (1)	HN1999000221A (fr)
HR (1)	HRP20010478A2 (fr)
HU (1)	HUP0104910A3 (fr)
ID (1)	ID29031A (fr)
IL (1)	IL143510A0 (fr)
IS (1)	IS5941A (fr)
MA (1)	MA26715A1 (fr)
NO (1)	NO20013149L (fr)
NZ (1)	NZ511796A (fr)
OA (1)	OA11732A (fr)
PA (1)	PA8488101A1 (fr)
PE (1)	PE20001371A1 (fr)
PL (1)	PL349091A1 (fr)
SK (1)	SK8762001A3 (fr)
TN (1)	TNSN99253A1 (fr)
TR (2)	TR200200938T2 (fr)
UY (1)	UY25869A1 (fr)
WO (1)	WO2000039125A1 (fr)
YU (1)	YU40701A (fr)

Families Citing this family (55)

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EP1118858A3 (fr) *	2000-01-12	2003-07-09	Pfizer Limited	Méthode d'essai
EP1526134B1 (fr) *	2000-05-26	2008-09-03	Pfizer Limited	Derives de triazolyltropane comme modulateurs de ccr5
US6511994B2 (en)	2000-10-11	2003-01-28	Merck & Co., Inc.	Modulators of CCR5 chemokine receptor activity
US6531484B2 (en)	2000-10-11	2003-03-11	Merck & Co., Inc.	Pyrrolidine modulators of CCR5 chemokine receptor activity
US6855724B2 (en)	2002-04-08	2005-02-15	Agouron Pharmaceuticals, Inc.	Tropane derivatives useful in therapy
US7202259B2 (en)	2002-11-18	2007-04-10	Euro-Celtique S.A.	Therapeutic agents useful for treating pain
WO2004050024A2 (fr)	2002-11-27	2004-06-17	Incyte Corporation	Derives de la 3-aminopyrrolidine modulateurs des recepteurs de la chemoquine
EP1571146A4 (fr) *	2002-12-10	2010-09-01	Ono Pharmaceutical Co	Composes heterocycliques contenant de l'azote et leur utilisation medicale
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US7332508B2 (en)	2002-12-18	2008-02-19	Novo Nordisk A/S	Substituted homopiperidine, piperidine or pyrrolidine derivatives
JP4736043B2 (ja)	2003-03-14	2011-07-27	小野薬品工業株式会社	含窒素複素環誘導体およびそれらを有効成分とする薬剤
EP1619193A4 (fr)	2003-04-18	2010-08-11	Ono Pharmaceutical Co	Compose de spiropiperidine et son utilisation medicinale
CA2579609A1 (fr)	2003-09-10	2005-03-17	Virochem Pharma Inc.	Composes de spirohydantoine et procedes de modulation de l'activite des recepteurs de chimiokine
WO2005044192A2 (fr) *	2003-10-28	2005-05-19	Amgen Inc.	Composes triazole et utilisations associees
WO2005075455A2 (fr)	2004-01-30	2005-08-18	Euro-Celtique S.A.	Procedes d'elaboration de composes de 4-tetrazolyl-4-phenylpiperidine
TW200610761A (en) *	2004-04-23	2006-04-01	Astrazeneca Ab	Chemical compounds
TWI396686B (zh)	2004-05-21	2013-05-21	Takeda Pharmaceutical	環狀醯胺衍生物、以及其製品和用法
ATE382623T1 (de)	2004-06-09	2008-01-15	Hoffmann La Roche	Octahydropyrrolo(3,4-c)pyrrolderivate und deren verwendung als antivirale mitteln
SE0401656D0 (sv) *	2004-06-24	2004-06-24	Astrazeneca Ab	Chemical compounds
WO2006004142A1 (fr) *	2004-06-30	2006-01-12	Banyu Pharmaceutical Co., Ltd.	Dérivés de biaryles
AU2005283326B2 (en)	2004-09-13	2011-07-21	Ono Pharmaceutical Co., Ltd.	Nitrogenous heterocyclic derivative and medicine containing the same as an active ingredient
GB0510139D0 (en) *	2005-05-18	2005-06-22	Addex Pharmaceuticals Sa	Novel compounds B1
GB0510141D0 (en) *	2005-05-18	2005-06-22	Addex Pharmaceuticals Sa	Novel compounds B3
EP1889622A4 (fr)	2005-05-31	2009-12-23	Ono Pharmaceutical Co	Compose de spiropiperidine et son utilisation medicinale
US7665658B2 (en)	2005-06-07	2010-02-23	First Data Corporation	Dynamic aggregation of payment transactions
CA2612325A1 (fr) *	2005-06-15	2006-12-28	Anormed Inc.	Composes de liaison au recepteur de la chimiokine
WO2006136917A1 (fr) *	2005-06-22	2006-12-28	Pfizer Limited	Derives de triazolylpiperidine et leur utilisation a des fins therapeutiques
HUP0500920A2 (en) *	2005-10-05	2007-07-30	Richter Gedeon Nyrt	Oxadiazole derivatives, process for their preparation and their use
EP1940781A1 (fr)	2005-10-19	2008-07-09	F.Hoffmann-La Roche Ag	Phénylacétamides en tant qu'inhibiteurs de nnrt
WO2007049771A1 (fr)	2005-10-28	2007-05-03	Ono Pharmaceutical Co., Ltd.	Compose contenant un groupe basique et son utilisation
PT1961744E (pt)	2005-11-18	2013-05-15	Ono Pharmaceutical Co	Composto que contém um grupo básico e sua utilização
EP1963303A2 (fr) *	2005-12-08	2008-09-03	Pfizer Limited	Composes chimiques
RU2008140144A (ru)	2006-03-10	2010-04-20	Оно Фармасьютикал Ко., Лтд. (Jp)	Азотосодержащее гетероциклическое производное и фармацевтическое средство, включающее такое производное в качестве активного ингредиента
US8618122B2 (en)	2006-05-16	2013-12-31	Ono Pharmaceutical Co., Ltd.	Compound having acidic group which may be protected, and use thereof
WO2008016006A1 (fr)	2006-07-31	2008-02-07	Ono Pharmaceutical Co., Ltd.	Composé auquel un groupe cyclique est lié par une liaison spiro et son utilisation
DE602007013573D1 (de)	2006-08-16	2011-05-12	Hoffmann La Roche	Nicht-nukleosidische reverse-transkriptase-hemmer
ES2550152T3 (es)	2006-12-13	2015-11-04	F. Hoffmann-La Roche Ag	Derivados de 2-(piperidin-4-il)-4-fenoxi-o fenilamino-pirimidina como inhibidores no nucleósidos de transcriptasa inversa
WO2009010480A1 (fr) *	2007-07-13	2009-01-22	Euroscreen S.A.	Dérivés de benzylamide de l'acide 1-{2-[(diphényl)amino]-éthyl}-pipéridine-4-carboxylique et composés associés comme agonistes de ccr5 pour le traitement de maladies immunes et inflammatoires
WO2009027820A2 (fr)	2007-08-31	2009-03-05	Purdue Pharma L.P.	Composés de pipéridine de type quinoxaline substituée et leurs utilisations
WO2010129351A1 (fr)	2009-04-28	2010-11-11	Schepens Eye Research Institute	Procédé pour identifier et pour traiter une dégénérescence maculaire liée à l'âge
CN102822163B (zh)	2009-12-23	2016-01-20	艾恩伍德医药品股份有限公司	Crth2调节剂
US20130259830A1 (en)	2010-07-12	2013-10-03	Ironwood Pharmaceuticals, Inc.	Crth2 modulators
WO2012009137A1 (fr)	2010-07-12	2012-01-19	Ironwood Pharmaceuticals, Inc.	Modulateurs de crth2
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1999
- 1999-11-30 US US09/451,826 patent/US7217714B1/en not_active Expired - Fee Related
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- 1999-12-01 PL PL99349091A patent/PL349091A1/xx not_active Application Discontinuation
- 1999-12-01 SK SK876-2001A patent/SK8762001A3/sk unknown
- 1999-12-01 HR HR20010478A patent/HRP20010478A2/hr not_active Application Discontinuation
- 1999-12-01 AU AU12904/00A patent/AU769449B2/en not_active Ceased
- 1999-12-01 KR KR1020017008078A patent/KR20010099931A/ko not_active Ceased
- 1999-12-01 EA EA200100588A patent/EA200100588A1/ru unknown
- 1999-12-01 EP EP99956267A patent/EP1140920A1/fr not_active Withdrawn
- 1999-12-01 WO PCT/IB1999/001913 patent/WO2000039125A1/fr not_active Ceased
- 1999-12-01 EE EEP200100344A patent/EE200100344A/xx unknown
- 1999-12-01 TR TR2002/00938T patent/TR200200938T2/xx unknown
- 1999-12-01 IL IL14351099A patent/IL143510A0/xx unknown
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- 1999-12-01 JP JP2000591036A patent/JP3522691B2/ja not_active Expired - Fee Related
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- 1999-12-01 CA CA002350573A patent/CA2350573C/fr not_active Expired - Fee Related
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- 1999-12-01 YU YU40701A patent/YU40701A/sh unknown
- 1999-12-01 CZ CZ20012297A patent/CZ20012297A3/cs unknown
- 1999-12-01 HK HK02101506.3A patent/HK1039942B/zh not_active IP Right Cessation
- 1999-12-01 CN CNB998149810A patent/CN1150192C/zh not_active Expired - Fee Related
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- 1999-12-21 UY UY25869A patent/UY25869A1/es unknown
- 1999-12-22 DZ DZ990278A patent/DZ2978A1/fr active
- 1999-12-22 TN TNTNSN99253A patent/TNSN99253A1/fr unknown
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- 1999-12-23 PA PA19998488101A patent/PA8488101A1/es unknown
- 1999-12-23 HN HN1999000221A patent/HN1999000221A/es unknown
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2001
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- 2001-06-22 NO NO20013149A patent/NO20013149L/no not_active Application Discontinuation
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Also Published As

Publication number	Publication date
PE20001371A1 (es)	2000-12-14
TR200200938T2 (tr)	2002-05-21
PL349091A1 (en)	2002-07-01
HUP0104910A3 (en)	2003-12-29
NO20013149D0 (no)	2001-06-22
JP3522691B2 (ja)	2004-04-26
CZ20012297A3 (cs)	2002-09-11
HK1039942B (zh)	2004-12-03
IL143510A0 (en)	2002-04-21
JP2004099618A (ja)	2004-04-02
KR20010099931A (ko)	2001-11-09
BR9916585A (pt)	2001-10-16
PA8488101A1 (es)	2002-02-21
TNSN99253A1 (fr)	2005-11-10
AU1290400A (en)	2000-07-31
CA2350573C (fr)	2007-01-30
NZ511796A (en)	2003-11-28
CA2350573A1 (fr)	2000-07-06
AR023345A1 (es)	2002-09-04
CN1150192C (zh)	2004-05-19
BG105709A (en)	2002-02-28
NO20013149L (no)	2001-08-23
UY25869A1 (es)	2001-08-27
EP1140920A1 (fr)	2001-10-10
TR200101867T2 (tr)	2001-11-21
HK1039942A1 (en)	2002-05-17
MA26715A1 (fr)	2004-12-20
EE200100344A (et)	2002-10-15
EA200100588A1 (ru)	2002-02-28
AP2001002187A0 (en)	2001-06-30
YU40701A (sh)	2004-05-12
AU769449B2 (en)	2004-01-29
HUP0104910A2 (en)	2002-10-28
CR6393A (es)	2004-03-24
US7217714B1 (en)	2007-05-15
AR023363A1 (es)	2002-09-04
SK8762001A3 (en)	2003-02-04
HN1999000221A (es)	2001-02-02
GEP20043161B (en)	2004-01-26
ID29031A (id)	2001-07-26
WO2000039125A1 (fr)	2000-07-06
CN1331691A (zh)	2002-01-16
IS5941A (is)	2001-05-15
HRP20010478A2 (en)	2002-06-30
OA11732A (en)	2005-05-12
JP2002533461A (ja)	2002-10-08

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MA26715A1 (fr)	2004-12-20	Composes chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant.
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FR2708608B1 (fr)	1995-10-27	Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
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DZ2155A1 (fr)	2002-10-26	Aazétidines, procédé pour leur préparation, et co mpositions pharmaceutiques les contenant.