ECSP056148A - Compuestos inmunosupresores y composiciones - Google Patents
Compuestos inmunosupresores y composicionesInfo
- Publication number
- ECSP056148A ECSP056148A EC2005006148A ECSP056148A ECSP056148A EC SP056148 A ECSP056148 A EC SP056148A EC 2005006148 A EC2005006148 A EC 2005006148A EC SP056148 A ECSP056148 A EC SP056148A EC SP056148 A ECSP056148 A EC SP056148A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- immunosuppressor
- compositions
- immunosuppressants
- prevention
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000003018 immunosuppressive agent Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 102000036530 EDG receptors Human genes 0.000 abstract 1
- 108091007263 EDG receptors Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000019491 signal transduction Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/12—Radicals substituted by oxygen atoms
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- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
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- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
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- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
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Abstract
La presente invención se refiere a inmunosupresores, a procesos para su producción, a sus usos y a composiciones farmacéuticas que los contienen. La invención proporciona una clase novedosa de compuestos útiles en el tratamiento o en la prevención de enfermedades o trastornos mediados por las interacciones de los linfocitos, en particular las enfermedades asociadas con la transducción de señal mediada por el receptor de EDG
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47193103P | 2003-05-19 | 2003-05-19 | |
| US56196804P | 2004-04-14 | 2004-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP056148A true ECSP056148A (es) | 2006-04-19 |
Family
ID=33479305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2005006148A ECSP056148A (es) | 2003-05-19 | 2005-11-10 | Compuestos inmunosupresores y composiciones |
Country Status (32)
| Country | Link |
|---|---|
| US (2) | US20050014728A1 (es) |
| EP (4) | EP3138835A1 (es) |
| JP (2) | JP4700616B2 (es) |
| KR (1) | KR101118779B1 (es) |
| CN (1) | CN102875413A (es) |
| AR (1) | AR044403A1 (es) |
| AU (2) | AU2004240637A1 (es) |
| BR (1) | BRPI0410741B8 (es) |
| CA (1) | CA2524047C (es) |
| CL (1) | CL2004001119A1 (es) |
| CY (1) | CY1118299T1 (es) |
| DK (1) | DK1633336T3 (es) |
| EC (1) | ECSP056148A (es) |
| ES (1) | ES2593463T3 (es) |
| HR (1) | HRP20161156T1 (es) |
| HU (1) | HUE030772T2 (es) |
| IL (1) | IL171683A (es) |
| IS (1) | IS3007B (es) |
| LT (1) | LT1633336T (es) |
| MA (1) | MA27807A1 (es) |
| MX (1) | MXPA05012462A (es) |
| MY (1) | MY150088A (es) |
| NO (1) | NO334457B1 (es) |
| NZ (1) | NZ543241A (es) |
| PE (1) | PE20050626A1 (es) |
| PL (1) | PL1633336T3 (es) |
| PT (1) | PT1633336T (es) |
| RU (1) | RU2009132108A (es) |
| SI (1) | SI1633336T1 (es) |
| TN (1) | TNSN05294A1 (es) |
| TW (1) | TWI355931B (es) |
| WO (1) | WO2004103306A2 (es) |
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