ECSP088626A - Compuestos para el tratamiento de trastornos inflamatorios - Google Patents

Compuestos para el tratamiento de trastornos inflamatorios

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Publication number
ECSP088626A
ECSP088626A EC2008008626A ECSP088626A ECSP088626A EC SP088626 A ECSP088626 A EC SP088626A EC 2008008626 A EC2008008626 A EC 2008008626A EC SP088626 A ECSP088626 A EC SP088626A EC SP088626 A ECSP088626 A EC SP088626A
Authority
EC
Ecuador
Prior art keywords
compounds
treatment
inflammatory disorders
aggrecanase
tace
Prior art date
Application number
EC2008008626A
Other languages
English (en)
Inventor
Joseph A Kozlowski
Michael K Wong
Bandarpalle B Shankar
Guowel Zhou
Brian J Lavey
Neng Yang Shih
Ling Tong
Kristin E Rosner
M Arshad Siddiqui
Chaoyang Dai
Dansu Li
Vinay M Girijavallabhan
Janeta Popovici-Muller
Wensheng Yu
De-Yi Yang
Seong-Heon Kim
Aneta M Micula
Razia Rizvi
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38038495&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088626(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of ECSP088626A publication Critical patent/ECSP088626A/es

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    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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Abstract

Esta invención se refiere a compuestos de fórmula (I): (I)o una de sus sales, solvatos o isómeros aceptables para uso farmacéutico, que pueden ser útiles para el tratamiento de enfermedades o afecciones mediadas por las MMP, ADAM, TACE, agrecanasa, TNF-a o combinaciones de las mismas.
EC2008008626A 2006-01-17 2008-07-16 Compuestos para el tratamiento de trastornos inflamatorios ECSP088626A (es)

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EC2008008625A ECSP088625A (es) 2006-01-17 2008-07-16 Compuestos para el tratamiento de trastornos inflamatorios

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KR (2) KR20080085222A (es)
CN (2) CN101410390A (es)
AR (2) AR059037A1 (es)
AU (2) AU2007207711A1 (es)
BR (2) BRPI0706599A2 (es)
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EC (2) ECSP088626A (es)
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NO (2) NO20083567L (es)
PE (2) PE20071241A1 (es)
RU (2) RU2008133383A (es)
TW (2) TW200736247A (es)
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PE20071241A1 (es) 2008-01-14
US7772263B2 (en) 2010-08-10
AR059037A1 (es) 2008-03-12
WO2007084451A1 (en) 2007-07-26
CA2637198A1 (en) 2007-07-26
JP2009523797A (ja) 2009-06-25
AR059036A1 (es) 2008-03-12
EP1973900B1 (en) 2017-04-05
US7683088B2 (en) 2010-03-23
KR20080085221A (ko) 2008-09-23
EP1973901B1 (en) 2014-12-17
RU2008133383A (ru) 2010-02-27
KR20080085222A (ko) 2008-09-23
EP1973901A1 (en) 2008-10-01
IL192691A0 (en) 2009-02-11
AU2007207711A1 (en) 2007-07-26
WO2007084455A1 (en) 2007-07-26
US7524842B2 (en) 2009-04-28
TW200736247A (en) 2007-10-01
PE20071240A1 (es) 2008-01-14
NO20083567L (no) 2008-10-16
JP2009523796A (ja) 2009-06-25
BRPI0706599A2 (pt) 2011-03-29
US8178553B2 (en) 2012-05-15
US20090156586A1 (en) 2009-06-18
TW200738688A (en) 2007-10-16
CA2637196A1 (en) 2007-07-26
EP1973900A1 (en) 2008-10-01
IL192690A0 (en) 2009-02-11
US20070265299A1 (en) 2007-11-15
BRPI0706598A2 (pt) 2011-04-05
NO20083568L (no) 2008-10-16
AU2007207707A1 (en) 2007-07-26
ECSP088625A (es) 2008-08-29
RU2008133382A (ru) 2010-02-27
CN101410390A (zh) 2009-04-15
ZA200806072B (en) 2009-04-29
CN101405286A (zh) 2009-04-08
US20100120838A1 (en) 2010-05-13
US20070197564A1 (en) 2007-08-23

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