ECSP13012658A - Composiciones y métodos para el tratamiento de la mielofibrosis - Google Patents

Composiciones y métodos para el tratamiento de la mielofibrosis

Info

Publication number
ECSP13012658A
ECSP13012658A ECSP13012658A ECSP13012658A EC SP13012658 A ECSP13012658 A EC SP13012658A EC SP13012658 A ECSP13012658 A EC SP13012658A EC SP13012658 A ECSP13012658 A EC SP13012658A
Authority
EC
Ecuador
Prior art keywords
methods
compositions
honeyfibrosis
treatment
amino
Prior art date
Application number
Other languages
English (en)
Inventor
Arvind Jayan
Janice Cacace
Original Assignee
Targegen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46024747&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP13012658(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Targegen Inc filed Critical Targegen Inc
Publication of ECSP13012658A publication Critical patent/ECSP13012658A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

En la presente memoria se proporcionan composiciones y métodos para tratar mielofibrosis en un sujeto. Los métodos comprenden administrar al sujeto una cantidad eficaz de compuesto que es N-terc-butil-3-[(5-metil-2-{[4-(2-pirrolidin-1-iletoxi)fenil]amino}pirimidin-4-il)amino]bencenosulfonamida o una sal farmacéuticamente aceptable del mismo o un hidrato del mismo.
ECSP13012658 2010-11-07 2013-06-04 Composiciones y métodos para el tratamiento de la mielofibrosis ECSP13012658A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41092410P 2010-11-07 2010-11-07

Publications (1)

Publication Number Publication Date
ECSP13012658A true ECSP13012658A (es) 2013-08-30

Family

ID=46024747

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012658 ECSP13012658A (es) 2010-11-07 2013-06-04 Composiciones y métodos para el tratamiento de la mielofibrosis

Country Status (36)

Country Link
US (5) US10391094B2 (es)
EP (2) EP2635282B1 (es)
JP (1) JP6133211B2 (es)
KR (4) KR20200083676A (es)
CN (2) CN103282036B (es)
AU (2) AU2010363329A1 (es)
BR (1) BR112013011184A2 (es)
CA (2) CA2816957A1 (es)
CL (1) CL2013001252A1 (es)
CO (1) CO6801724A2 (es)
DK (1) DK2635282T3 (es)
DO (1) DOP2013000097A (es)
EC (1) ECSP13012658A (es)
ES (1) ES2930650T3 (es)
HR (1) HRP20221269T1 (es)
HU (1) HUE060254T2 (es)
IL (1) IL226101A (es)
LT (1) LT2635282T (es)
MA (1) MA34723B1 (es)
MX (2) MX360246B (es)
MY (1) MY161164A (es)
NI (1) NI201300038A (es)
NZ (1) NZ611363A (es)
PE (1) PE20140389A1 (es)
PH (1) PH12013500924A1 (es)
PL (1) PL2635282T3 (es)
PT (1) PT2635282T (es)
RS (1) RS63996B1 (es)
RU (1) RU2616262C2 (es)
SG (1) SG190134A1 (es)
SI (1) SI2635282T1 (es)
SM (1) SMT202200453T1 (es)
TW (1) TWI531389B (es)
UA (1) UA114076C2 (es)
WO (2) WO2012060847A1 (es)
ZA (1) ZA201303423B (es)

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US8604042B2 (en) 2005-11-01 2013-12-10 Targegen, Inc. Bi-aryl meta-pyrimidine inhibitors of kinases
WO2012060847A1 (en) * 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
WO2013059548A1 (en) * 2011-10-19 2013-04-25 Sanofi Compositions and methods for treating cancer using jak2 inhibitor
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WO2017018385A1 (ja) * 2015-07-24 2017-02-02 公立大学法人名古屋市立大学 骨髄線維症の状態の診断を補助する方法、予後の予測を補助する方法、及び治療効果のモニター方法、並びにそれらの方法に用いるマーカー及び装置
CN105919955A (zh) * 2016-06-13 2016-09-07 佛山市腾瑞医药科技有限公司 一种鲁索利替尼制剂及其应用
HUE067225T2 (hu) 2016-07-27 2024-10-28 Acceleron Pharma Inc Mielofibrózis kezelésére szolgáló készítmények
JP7169005B2 (ja) * 2018-01-16 2022-11-10 深▲チェン▼市塔吉瑞生物医薬有限公司 キナーゼ活性を阻害するためのジフェニルアミノピリミジン系化合物
CN113286584A (zh) * 2018-09-25 2021-08-20 生物医学影响公司 治疗骨髓增生性病症的方法
EA202190751A1 (ru) * 2018-09-25 2021-06-28 Импакт Биомедисинс, Инк. Способы лечения миелопролиферативных расстройств
EP3923948A4 (en) * 2019-02-12 2022-11-16 Impact Biomedicines, Inc. CRYSTALLINE SHAPES OF A JAK2 INHIBITOR
FR3092581A1 (fr) * 2019-02-12 2020-08-14 Impact Biomedicines, Inc Formes cristallines d'un inhibiteur de jak2
JP2022549506A (ja) 2019-09-27 2022-11-25 ディスク・メディシン・インコーポレイテッド 骨髄線維症および関連状態を処置するための方法
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JP7675724B2 (ja) * 2019-12-20 2025-05-13 インターベット インターナショナル ベー． フェー． ピラゾール医薬組成物
WO2021207051A1 (en) * 2020-04-06 2021-10-14 Bristol-Myers Squibb Company Methods of treating acute respiratory disorders
KR20230012539A (ko) 2020-05-13 2023-01-26 디스크 메디슨, 인크. 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
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CL2013001252A1 (es) 2014-03-28
ES2930650T3 (es) 2022-12-20
IL226101A0 (en) 2013-06-27
PT2635282T (pt) 2023-01-05
WO2012061833A1 (en) 2012-05-10
MA34723B1 (fr) 2013-12-03
MX2013005020A (es) 2013-07-29
KR20240029118A (ko) 2024-03-05
PE20140389A1 (es) 2014-03-26
CN108125923A (zh) 2018-06-08
CN103282036B (zh) 2018-01-26
US10391094B2 (en) 2019-08-27
MX381913B (es) 2025-03-13
RU2616262C2 (ru) 2017-04-13
US20130252988A1 (en) 2013-09-26
US20130243853A1 (en) 2013-09-19
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DK2635282T3 (da) 2022-10-17
IL226101A (en) 2017-12-31
PL2635282T3 (pl) 2023-02-06
HRP20221269T1 (hr) 2022-12-23
MY161164A (en) 2017-04-14
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