EE04851B1 - 4H-1-bensopüraan-4-ooni derivaatide kasutamine ravimi valmistamiseks silelihasrakkude proliferatsiooni inhibeerimiseks - Google Patents

4H-1-bensopüraan-4-ooni derivaatide kasutamine ravimi valmistamiseks silelihasrakkude proliferatsiooni inhibeerimiseks

Info

Publication number
EE04851B1
EE04851B1 EEP200100385A EEP200100385A EE04851B1 EE 04851 B1 EE04851 B1 EE 04851B1 EE P200100385 A EEP200100385 A EE P200100385A EE P200100385 A EEP200100385 A EE P200100385A EE 04851 B1 EE04851 B1 EE 04851B1
Authority
EE
Estonia
Prior art keywords
benzopyran
medicament
derivatives
manufacture
cell proliferation
Prior art date
Application number
EEP200100385A
Other languages
English (en)
Estonian (et)
Inventor
Campbell Patterson Winston
Ann Dumont Jennifer
Original Assignee
Aventis Pharmaceuticals Inc.
Board Of Regents, The University Of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc., Board Of Regents, The University Of Texas System filed Critical Aventis Pharmaceuticals Inc.
Publication of EE200100385A publication Critical patent/EE200100385A/xx
Publication of EE04851B1 publication Critical patent/EE04851B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
EEP200100385A 1999-02-01 2000-01-18 4H-1-bensopüraan-4-ooni derivaatide kasutamine ravimi valmistamiseks silelihasrakkude proliferatsiooni inhibeerimiseks EE04851B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24338099A 1999-02-01 1999-02-01
US09/468,665 US6399633B1 (en) 1999-02-01 1999-12-21 Use of 4-H-1-benzopryan-4-one derivatives as inhibitors of smooth muscle cell proliferation
PCT/US2000/001104 WO2000044362A2 (en) 1999-02-01 2000-01-18 The use of 4-h-1-benzopyran-4-one derivatives as inhibitors of smooth muscle cell proliferation

Publications (2)

Publication Number Publication Date
EE200100385A EE200100385A (et) 2002-12-16
EE04851B1 true EE04851B1 (et) 2007-06-15

Family

ID=22918541

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100385A EE04851B1 (et) 1999-02-01 2000-01-18 4H-1-bensopüraan-4-ooni derivaatide kasutamine ravimi valmistamiseks silelihasrakkude proliferatsiooni inhibeerimiseks

Country Status (38)

Country Link
US (1) US6399633B1 (de)
EP (1) EP1150746B1 (de)
JP (1) JP4755759B2 (de)
KR (1) KR100793047B1 (de)
CN (1) CN1219556C (de)
AP (1) AP1469A (de)
AR (1) AR042569A1 (de)
AT (1) ATE275428T1 (de)
AU (1) AU777368B2 (de)
BG (1) BG65151B1 (de)
BR (1) BR0007911A (de)
CA (1) CA2360668C (de)
CR (1) CR6448A (de)
CZ (1) CZ300395B6 (de)
DE (1) DE60013555T2 (de)
DK (1) DK1150746T3 (de)
EA (1) EA004786B1 (de)
EE (1) EE04851B1 (de)
ES (1) ES2226792T3 (de)
HK (1) HK1042445B (de)
HR (1) HRP20010521A2 (de)
HU (1) HU229263B1 (de)
ID (1) ID30180A (de)
IL (1) IL144668A (de)
ME (1) MEP10508A (de)
NO (1) NO330512B1 (de)
NZ (1) NZ512822A (de)
OA (1) OA11755A (de)
PL (1) PL197693B1 (de)
PT (1) PT1150746E (de)
RS (1) RS50242B (de)
SI (1) SI1150746T1 (de)
SK (1) SK286747B6 (de)
TR (1) TR200102223T2 (de)
TW (1) TWI273907B (de)
UA (1) UA73110C2 (de)
WO (1) WO2000044362A2 (de)
ZA (1) ZA200105596B (de)

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US7563810B2 (en) 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
KR101224235B1 (ko) 2003-04-11 2013-01-25 메디뮨 엘엘씨 재조합 ｉｌ­９ 항체 및 그의 용도
US20060228350A1 (en) * 2003-08-18 2006-10-12 Medimmune, Inc. Framework-shuffling of antibodies
EP1660186B1 (de) 2003-08-18 2013-12-25 MedImmune, LLC Humanisierung von antikörpern
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EP1869192B1 (de) 2005-03-18 2016-01-20 MedImmune, LLC Rahmenmischung von antikörpern
KR20080025174A (ko) 2005-06-23 2008-03-19 메디뮨 인코포레이티드 응집 및 단편화 프로파일이 최적화된 항체 제제
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EP4063391A1 (de) 2012-07-25 2022-09-28 Celldex Therapeutics, Inc. Anti-kit-antikörper und verwendungen davon
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JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
EP3003390B1 (de) 2013-06-06 2021-07-07 Pierre Fabre Médicament Anti-c10orf54-antikörper und verwendungen davon
CN105764526B (zh) 2013-08-26 2020-12-15 生物技术研发公司 编码抗唾液酸化路易斯a抗原的人抗体的核酸
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Also Published As

Publication number Publication date
HRP20010521A2 (en) 2002-08-31
CZ20012804A3 (cs) 2002-08-14
KR100793047B1 (ko) 2008-01-10
MEP10508A (en) 2010-06-10
EA200100742A1 (ru) 2001-12-24
OA11755A (en) 2005-07-19
ZA200105596B (en) 2002-10-07
SK286747B6 (sk) 2009-04-06
EP1150746B1 (de) 2004-09-08
NO20013335L (no) 2001-09-25
JP2002535356A (ja) 2002-10-22
AR042569A1 (es) 2005-06-29
PL350735A1 (en) 2003-01-27
US6399633B1 (en) 2002-06-04
DK1150746T3 (da) 2005-01-10
HUP0200804A3 (en) 2004-03-29
HK1042445A1 (en) 2002-08-16
TWI273907B (en) 2007-02-21
CZ300395B6 (cs) 2009-05-06
TR200102223T2 (tr) 2004-12-21
SK10862001A3 (sk) 2002-07-02
ID30180A (id) 2001-11-08
CA2360668C (en) 2009-03-17
AP1469A (en) 2005-09-26
IL144668A0 (en) 2002-05-23
DE60013555T2 (de) 2005-09-29
CA2360668A1 (en) 2000-08-03
PL197693B1 (pl) 2008-04-30
NO330512B1 (no) 2011-05-09
SI1150746T1 (en) 2005-02-28
JP4755759B2 (ja) 2011-08-24
RS50242B (sr) 2009-07-15
BG105751A (en) 2002-02-28
AU3209800A (en) 2000-08-18
NZ512822A (en) 2005-01-28
CN1338958A (zh) 2002-03-06
ES2226792T3 (es) 2005-04-01
IL144668A (en) 2005-06-19
PT1150746E (pt) 2004-12-31
EP1150746A2 (de) 2001-11-07
WO2000044362A2 (en) 2000-08-03
EA004786B1 (ru) 2004-08-26
WO2000044362A3 (en) 2001-04-05
AP2001002218A0 (en) 2001-09-30
EE200100385A (et) 2002-12-16
HK1042445B (zh) 2006-01-13
YU54401A (sh) 2004-05-12
BG65151B1 (bg) 2007-04-30
AU777368B2 (en) 2004-10-14
ATE275428T1 (de) 2004-09-15
NO20013335D0 (no) 2001-07-05
KR20010093309A (ko) 2001-10-27
HU229263B1 (en) 2013-10-28
CN1219556C (zh) 2005-09-21
DE60013555D1 (de) 2004-10-14
UA73110C2 (en) 2005-06-15
CR6448A (es) 2004-03-17
HUP0200804A2 (hu) 2002-12-28
BR0007911A (pt) 2001-10-16

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