EE200300306A - Oksübensamiidi derivaadid, nende valmistamine ja kasutamine Xa-teguri inhibiitoritena ning neid sisaldav ravimpreparaat - Google Patents
Oksübensamiidi derivaadid, nende valmistamine ja kasutamine Xa-teguri inhibiitoritena ning neid sisaldav ravimpreparaatInfo
- Publication number
- EE200300306A EE200300306A EEP200300306A EEP200300306A EE200300306A EE 200300306 A EE200300306 A EE 200300306A EE P200300306 A EEP200300306 A EE P200300306A EE P200300306 A EEP200300306 A EE P200300306A EE 200300306 A EE200300306 A EE 200300306A
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- Estonia
- Prior art keywords
- factor
- compounds
- formula
- preparation
- inhibitors
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229940123583 Factor Xa inhibitor Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 108010054265 Factor VIIa Proteins 0.000 abstract 3
- 108010074860 Factor Xa Proteins 0.000 abstract 3
- 229940012414 factor viia Drugs 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000001435 Thromboembolism Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000002785 anti-thrombosis Effects 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 125000002837 carbocyclic group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000002441 reversible effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D213/40—Acylated substituent nitrogen atom
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
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- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00128477A EP1217000A1 (de) | 2000-12-23 | 2000-12-23 | Faktor Xa und Faktor VIIa Inhibitoren |
| PCT/EP2001/014842 WO2002051831A1 (en) | 2000-12-23 | 2001-12-15 | Oxybenzamides derivatives as factor xa inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200300306A true EE200300306A (et) | 2003-10-15 |
Family
ID=8170811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300306A EE200300306A (et) | 2000-12-23 | 2001-12-15 | Oksübensamiidi derivaadid, nende valmistamine ja kasutamine Xa-teguri inhibiitoritena ning neid sisaldav ravimpreparaat |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US6953857B2 (de) |
| EP (2) | EP1217000A1 (de) |
| JP (1) | JP4238029B2 (de) |
| KR (1) | KR20030063465A (de) |
| CN (1) | CN1481376A (de) |
| AT (1) | ATE293617T1 (de) |
| AU (1) | AU2002219193B2 (de) |
| BR (1) | BR0116473A (de) |
| CA (1) | CA2432572C (de) |
| CZ (1) | CZ20031759A3 (de) |
| DE (1) | DE60110263T2 (de) |
| DK (1) | DK1349847T3 (de) |
| EE (1) | EE200300306A (de) |
| ES (1) | ES2240339T3 (de) |
| HR (1) | HRP20030505A2 (de) |
| HU (1) | HUP0401053A2 (de) |
| IL (2) | IL156588A0 (de) |
| MX (1) | MXPA03005398A (de) |
| NO (1) | NO20032820L (de) |
| NZ (1) | NZ526615A (de) |
| PL (1) | PL362519A1 (de) |
| PT (1) | PT1349847E (de) |
| RU (1) | RU2003122522A (de) |
| SI (1) | SI1349847T1 (de) |
| SK (1) | SK7802003A3 (de) |
| WO (1) | WO2002051831A1 (de) |
| ZA (1) | ZA200304094B (de) |
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