EG14227A - N-phenoxyalkyl imidazoles as selective infibitors of the thermoboxane synthetase enzyme,pharmaceutical compositions thereof and process for their preparation - Google Patents

N-phenoxyalkyl imidazoles as selective infibitors of the thermoboxane synthetase enzyme,pharmaceutical compositions thereof and process for their preparation

Info

Publication number: EG14227A
Authority: EG; Egypt
Prior art keywords: thermoboxane; infibitors; phenoxyalkyl; imidazoles; selective
Prior art date: 1978-12-13

Application number

EG743/79A

Other languages

English (en)

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-13

Filing date

1979-12-12

Publication date

1983-12-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10501705&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG14227(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1979-12-12 Application filed by Pfizer filed Critical Pfizer

1983-12-31 Application granted granted Critical

1983-12-31 Publication of EG14227A publication Critical patent/EG14227A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Diabetes (AREA)
Cardiology (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EG743/79A 1978-12-13 1979-12-12 N-phenoxyalkyl imidazoles as selective infibitors of the thermoboxane synthetase enzyme,pharmaceutical compositions thereof and process for their preparation EG14227A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7848367		1978-12-13

Publications (1)

Publication Number	Publication Date
EG14227A true EG14227A (en)	1983-12-31

Family

ID=10501705

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG743/79A EG14227A (en)	1978-12-13	1979-12-12	N-phenoxyalkyl imidazoles as selective infibitors of the thermoboxane synthetase enzyme,pharmaceutical compositions thereof and process for their preparation

Country Status (34)

Country	Link
US (2)	US4602016A (da)
JP (1)	JPS585197B2 (da)
KR (1)	KR830001243B1 (da)
AR (1)	AR227637A1 (da)
AT (1)	AT373879B (da)
AU (1)	AU517892B2 (da)
BE (1)	BE880584A (da)
CA (1)	CA1108137A (da)
CH (1)	CH644597A5 (da)
CS (1)	CS216517B2 (da)
DD (1)	DD147943A5 (da)
DE (1)	DE2950019A1 (da)
DK (1)	DK471479A (da)
EG (1)	EG14227A (da)
ES (1)	ES8101556A1 (da)
FI (1)	FI70888C (da)
FR (1)	FR2444031A1 (da)
GB (1)	GB2038821B (da)
GR (1)	GR73003B (da)
HU (1)	HU183016B (da)
IE (1)	IE49318B1 (da)
IL (1)	IL58917A (da)
IT (1)	IT1194900B (da)
LU (1)	LU81985A1 (da)
NL (1)	NL177749C (da)
NO (1)	NO153135C (da)
NZ (1)	NZ192360A (da)
PH (1)	PH15056A (da)
PL (1)	PL134005B1 (da)
PT (1)	PT70571A (da)
SE (1)	SE444937B (da)
SU (1)	SU878195A3 (da)
YU (1)	YU301879A (da)
ZA (1)	ZA796708B (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4350696A (en) *	1980-03-08	1982-09-21	Pfizer Inc.	Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
US4444775A (en) *	1981-06-22	1984-04-24	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridines
DE3148291A1 (de) *	1981-12-05	1983-06-09	Basf Ag, 6700 Ludwigshafen	Harnstoffderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
JPS58113178A (ja) *	1981-12-28	1983-07-05	Yamanouchi Pharmaceut Co Ltd	「お」−（１−イミダゾリル）アルキルオキシ（またはチオ）ベンゼン誘導体
US4588732A (en) *	1982-12-21	1986-05-13	Ciba-Geigy Corporation	Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US4470986A (en) *	1982-12-21	1984-09-11	Ciba-Geigy Corporation	Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors
NL8301550A (nl) *	1983-05-03	1984-12-03	Gist Brocades Nv	Imidazolethanol esters.
US4511573A (en) *	1983-05-17	1985-04-16	Ciba-Geigy Corporation	3-Substituted-2-(heteroaryl) indoles
PH22076A (en) *	1983-08-25	1988-05-20	Daiichi Seiyaku Co	Benzocycloalkane derivative
IT1212791B (it) *	1983-11-24	1989-11-30	Medea Res Srl	Derivato imidazolico adattivita' vasodilatatrice ed antitrombotica, sua preparazione e composizioni farmaceutiche che lo contengono.
ES8601148A1 (es) *	1984-12-10	1985-11-16	Ferrer Int	Procedimiento de obtencion de nuevos derivados imidazoliletoxiindanicos.
JPH0625141B2 (ja) *	1985-01-16	1994-04-06	三共株式会社	イミダゾ−ル誘導体およびその製法
NO166644C (no)	1986-01-28	1991-08-21	Sankyo Co	Analogifremgangsmaate til fremstilling av tianaftenderivater.
ATE90076T1 (de)	1986-03-27	1993-06-15	Merck Frosst Canada Inc	Tetrahydrocarbazole ester.
JPS63179840A (ja) *	1986-07-24	1988-07-23	Yamanouchi Pharmaceut Co Ltd	新規化学物質
DE3860908D1 (de) *	1987-04-03	1990-12-06	Cl Pharma	Neue 2-thienyloxyessigsaeurederivate, ein verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
JPH01125372A (ja) *	1988-09-12	1989-05-17	Yamanouchi Pharmaceut Co Ltd	イミダゾリルアルキルオキシベンゼン誘導体
DE4204686A1 (de) *	1992-02-17	1993-08-19	Gruenenthal Gmbh	Imidazolylphenolderivate, diese enthaltende arzneimittel sowie ein verfahren zur herstellung dieser verbindungen und arzneimitteln
ES2201104T3 (es) *	1994-04-26	2004-03-16	Roche Palo Alto Llc	Derivados de benzociclohexilimidazoltiona.
AU2890899A (en) *	1998-03-13	1999-09-27	Pozen, Inc.	Prophylaxis and treatment of migraine headaches with thromboxane synthetase inhibitors and/or receptor antagonists
ES2172436B1 (es)	2000-10-31	2004-01-16	Almirall Prodesfarma Sa	Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
JP2005533830A (ja) *	2002-07-09	2005-11-10	ビー．エム．アール．エイ．コーポレイションベスローテンフェンノートシャップ	トロンボキサンａ２受容体アンタゴニストおよびｃｏｘ−２阻害剤の薬剤の組み合わせ
JP2007508242A (ja) *	2003-08-07	2007-04-05	ビー．エム．アール．エイ．コーポレイションベスローテンフェンノートシャップ	トロンボキサンａ２受容体アンタゴニストとシクロオキシゲネーゼ−１の阻害剤との組み合わせを伴う組成物および方法
KR101275814B1 (ko) *	2006-06-23	2013-06-18	삼성에스디아이 주식회사	분산제 화합물 및 그의 제조방법
EP2234608A2 (en)	2007-12-11	2010-10-06	Viamet Pharmaceuticals, Inc.	Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties
CN101811974B (zh) *	2010-04-15	2012-12-12	合肥医工医药有限公司	4-(3-(二甲氨基)丙氧基)-3,5-二甲氧基苯甲酸、其制法及医药用途
CN101851209B (zh) *	2010-06-21	2012-09-19	合肥医工医药有限公司	咪唑乙基香草酸醚、其制备方法及其医药用途
CA2874621A1 (en) *	2012-05-22	2013-11-28	Genentech, Inc.	N-substituted benzamides and their use in the treatment of pain
AU2013334664A1 (en)	2012-10-26	2015-05-07	Merck Sharp & Dohme Corp.	N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels
WO2023240378A1 (zh) *	2022-06-13	2023-12-21	南京医工医药技术有限公司	咪唑烷基香草酸醚衍生物及其用途
CN114736161B (zh) *	2022-06-13	2022-09-13	南京医工医药技术有限公司	咪唑烷基香草酸醚衍生物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3534061A (en) *	1967-12-04	1970-10-13	Parke Davis & Co	N-(alpha-(p-methoxyphenyl)-beta-nitrostyryl)-phenoxyalkyl pyrroles
US4085209A (en) *	1975-02-05	1978-04-18	Rohm And Haas Company	Preparation and safening effect of 1-substituted imidazole metal salt complexes
US4078071A (en) *	1976-03-08	1978-03-07	Syntex (U.S.A.) Inc.	Derivatives of substituted N-alkyl imidazoles
JPS5951943B2 (ja) *	1978-08-21	1984-12-17	キツセイ薬品工業株式会社	新規なイミダゾ−ル誘導体

1979
- 1979-11-07 DK DK471479A patent/DK471479A/da not_active Application Discontinuation
- 1979-11-19 US US06/095,755 patent/US4602016A/en not_active Expired - Lifetime
- 1979-12-10 GB GB7942535A patent/GB2038821B/en not_active Expired
- 1979-12-10 AR AR279215A patent/AR227637A1/es active
- 1979-12-11 NL NLAANVRAGE7908899,A patent/NL177749C/xx not_active IP Right Cessation
- 1979-12-11 ES ES486782A patent/ES8101556A1/es not_active Expired
- 1979-12-11 PT PT70571A patent/PT70571A/pt unknown
- 1979-12-11 YU YU03018/79A patent/YU301879A/xx unknown
- 1979-12-11 IL IL58917A patent/IL58917A/xx unknown
- 1979-12-11 IT IT41669/79A patent/IT1194900B/it active
- 1979-12-11 ZA ZA00796708A patent/ZA796708B/xx unknown
- 1979-12-11 NZ NZ192360A patent/NZ192360A/xx unknown
- 1979-12-11 GR GR60727A patent/GR73003B/el unknown
- 1979-12-11 HU HU79PI699A patent/HU183016B/hu unknown
- 1979-12-11 FI FI793868A patent/FI70888C/fi not_active IP Right Cessation
- 1979-12-11 SE SE7910204A patent/SE444937B/sv unknown
- 1979-12-12 LU LU81985A patent/LU81985A1/fr unknown
- 1979-12-12 CS CS798708A patent/CS216517B2/cs unknown
- 1979-12-12 IE IE2403/79A patent/IE49318B1/en unknown
- 1979-12-12 JP JP54161382A patent/JPS585197B2/ja not_active Expired
- 1979-12-12 NO NO794069A patent/NO153135C/no unknown
- 1979-12-12 PL PL1979220351A patent/PL134005B1/pl unknown
- 1979-12-12 AT AT0783379A patent/AT373879B/de not_active IP Right Cessation
- 1979-12-12 AU AU53725/79A patent/AU517892B2/en not_active Ceased
- 1979-12-12 FR FR7930438A patent/FR2444031A1/fr active Granted
- 1979-12-12 DE DE19792950019 patent/DE2950019A1/de not_active Ceased
- 1979-12-12 SU SU792854456A patent/SU878195A3/ru active
- 1979-12-12 EG EG743/79A patent/EG14227A/xx active
- 1979-12-12 BE BE0/198542A patent/BE880584A/fr not_active IP Right Cessation
- 1979-12-12 CA CA341,691A patent/CA1108137A/en not_active Expired
- 1979-12-12 KR KR1019790004397A patent/KR830001243B1/ko not_active Expired
- 1979-12-13 PH PH23412A patent/PH15056A/en unknown
- 1979-12-13 DD DD79217645A patent/DD147943A5/de unknown
- 1979-12-13 CH CH1106279A patent/CH644597A5/de not_active IP Right Cessation
1985
- 1985-03-21 US US06/714,422 patent/US4636500A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR830001242A (ko)	1983-04-29
HU183016B (en)	1984-04-28
IT1194900B (it)	1988-09-28
IT7941669A0 (it)	1979-12-11
PH15056A (en)	1982-06-03
NO153135C (no)	1986-01-22
LU81985A1 (fr)	1980-04-22
DK471479A (da)	1980-06-14
FI70888B (fi)	1986-07-18
PL134005B1 (en)	1985-07-31
SU878195A3 (ru)	1981-10-30
NO794069L (no)	1980-06-16
FI793868A7 (fi)	1980-06-14
CH644597A5 (de)	1984-08-15
NL177749B (nl)	1985-06-17
CS216517B2 (en)	1982-11-26
JPS585197B2 (ja)	1983-01-29
KR830001243B1 (ko)	1983-06-27
AR227637A1 (es)	1982-11-30
CA1108137A (en)	1981-09-01
PL220351A1 (da)	1980-12-01
JPS5585572A (en)	1980-06-27
GR73003B (da)	1984-01-24
IE49318B1 (en)	1985-09-18
AU5372579A (en)	1980-06-19
ZA796708B (en)	1981-08-26
DD147943A5 (de)	1981-04-29
ATA783379A (de)	1983-07-15
SE7910204L (sv)	1980-06-14
NL177749C (nl)	1985-11-18
DE2950019A1 (de)	1980-07-10
IL58917A0 (en)	1980-03-31
NO153135B (no)	1985-10-14
ES486782A0 (es)	1980-12-16
AT373879B (de)	1984-02-27
US4602016A (en)	1986-07-22
FR2444031A1 (fr)	1980-07-11
NL7908899A (nl)	1980-06-17
ES8101556A1 (es)	1980-12-16
SE444937B (sv)	1986-05-20
PT70571A (en)	1980-01-01
FR2444031B1 (da)	1983-06-10
GB2038821B (en)	1982-12-08
GB2038821A (en)	1980-07-30
YU301879A (en)	1983-01-21
US4636500A (en)	1987-01-13
NZ192360A (en)	1982-02-23
AU517892B2 (en)	1981-09-03
BE880584A (fr)	1980-06-12
FI70888C (fi)	1986-10-27
IE792403L (en)	1980-06-13
IL58917A (en)	1984-03-30

Publication	Publication Date	Title
GB2038821B (en)	1982-12-08	N-(phenoxyalkyl)imidazoles as selective inhibitors of the thromboxane synthetase enzyme pharmaceutical compositions thereof and process for their preparation
IL56734A0 (en)	1979-05-31	Phemoxyalkylcarboxylic acid derivatives,process for their preparation and pharmaceutical compositions containing thesame
DE3068020D1 (en)	1984-07-05	Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions
DE2962122D1 (en)	1982-03-25	17-alkylcarbonates of corticoids, process for their preparation and their use as medicines against dermatoses
PT70707A (en)	1980-02-01	Process for preparing n-benzyl-imidazoles as selective inhibitors of the thromboxane synthetase enzyme and pharmaceutical compositions
CY1250A (en)	1984-08-31	N-heterocyclyl-4-piperdinamines,methods for their preparation and pharmaceutical compositions comprising them
DE2960954D1 (en)	1981-12-24	1-aryloxy-3-nitratoalkylamino-2-propanols, process for their preparation and pharmaceutical compositions
DE3062586D1 (en)	1983-05-11	2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same
DE3161260D1 (en)	1983-12-01	Imidazole derivatives, process for their preparation and pharmaceutical compositions thereof
IL59104A (en)	1984-02-29	Heterotricyclic derivatives,process for their preparation and pharmaceutical compositions incorporating them
IL57040A (en)	1984-08-31	Imidazole derivatives,their preparation and pharmaceutical compositions containing them
IL57229A0 (en)	1979-09-30	Hydroxypropyl-imidazole derivatives,their production and pharmaceutical compositions containing them
DE2963573D1 (en)	1982-10-21	Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them
IL58377A (en)	1987-02-27	4-phenyl-1,3-benzodiazepines,method of preparing the same and pharmaceutical compositions comprising them
DE2964209D1 (en)	1983-01-13	Spiro-furanohydantoin derivatives, process for their preparation and pharmaceutical compositions containing them
DE3062884D1 (en)	1983-06-01	Spiro-hydantoin derivatives, process for their preparation and pharmaceutical compositions thereof
GB2019837A (en)	1979-11-07	N-Oxacyclic-alkylpiperidyl-diazacompounds, process for their manufacture and pharmaceutical compositions containing them
IL57115A (en)	1982-04-30	Hydrazone-beta-lactam antibiotics,their production and pharmaceutical compositions containing them
DE3361610D1 (en)	1986-02-06	Enzyme derivatives, process for preparing them and pharmaceutical compositions containing them
DE2966413D1 (en)	1983-12-22	Pyrimidinone derivatives, processes for preparing them and pharmaceutical compositions containing them
DE2862404D1 (en)	1984-06-20	Hydantoin derivatives, their preparation and pharmaceutical compositions containing them
DE3060894D1 (en)	1982-11-11	Benzimidazolone derivatives, process for their preparation and pharmaceutical compositions containing them
ZA794580B (en)	1981-04-29	N-phenylindoline derivatives,their production and pharmaceutical compositions containing them
DE3060079D1 (en)	1982-01-21	Spiro-quinolylhydantoins, process for their preparation and pharmaceutical compositions thereof
IL62747A (en)	1984-10-31	2-guanidinothiazole derivatives,process for the preparation thereof and pharmaceutical compositions comprising the same